Best TWAS P=5.66e-12 · Best GWAS P=2.93e-14 conditioned to 9.39e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | GAB1 | 0.04 | 0.03 | lasso | 4 | 0.02 | 0.00494 | 6.7 | -6.6 | 4.4e-11 | 0.66 | 0.25 | 0.24 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | GAB1 | 0.06 | 0.07 | lasso | 2 | 0.07 | 0.00008 | 6.7 | 6.9 | 5.7e-12 | -0.70 | 0.00 | 0.98 | TRUE |