[Hub]/) : Traits : Systolic Blood Pressure :

chr5:70,709,459-72,201,058

Best TWAS P=1.4e-09 · Best GWAS P=8.8e-08 conditioned to 0.985

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MAP1B 0.21 0.19 lasso 4 0.19 2.1e-15 5.3 5.5 3.5e-08 0.97 0.00 1.00 FALSE
2 GTEx Artery Aorta MAP1B 0.23 0.20 enet 16 0.22 3.6e-12 4.7 5.5 3.7e-08 0.86 0.03 0.96 FALSE
3 GTEx Artery Tibial MAP1B 0.47 0.46 lasso 4 0.47 4.2e-41 4.7 5.1 2.8e-07 0.83 0.07 0.92 FALSE
4 GTEx Brain Frontal Cortex BA9 MAP1B 0.28 0.10 lasso 5 0.14 1.5e-04 5.3 6.1 1.4e-09 0.88 0.01 0.96 TRUE
5 GTEx Cells Transformed fibroblasts MAP1B 0.23 0.23 lasso 5 0.25 9.7e-19 4.7 5.2 2.6e-07 0.92 0.03 0.97 FALSE
6 GTEx Skin Sun Exposed Lower leg MAP1B 0.08 0.07 lasso 2 0.06 1.6e-05 4.7 5.2 1.6e-07 0.82 0.06 0.90 FALSE
7 METSIM Adipose MAP1B 0.03 0.00 blup 463 0.01 2.6e-02 4.7 5.4 5.3e-08 0.47 0.04 0.63 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAP1B 0.06 0.02 blup 104 0.04 3.1e-05 4.7 5.5 3.2e-08 0.82 0.00 0.98 FALSE