[Hub]/) : Traits : Systolic Blood Pressure :

chr5:60,903,201-62,529,686

Best TWAS P=6.64e-14 · Best GWAS P=7.95e-13 conditioned to 0.446

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose KIF2A 0.05 0.02 lasso 4 0.02 1.1e-03 5.9 -7.0 2.1e-12 -0.63 0.09 0.53 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma IPO11 0.08 0.02 lasso 4 0.01 9.3e-02 7.1 7.4 1.5e-13 0.99 0.02 0.92 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma DIMT1L 0.09 0.04 lasso 3 0.04 3.0e-08 6.9 6.4 1.7e-10 0.87 0.01 0.98 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma IPO11 0.09 0.06 blup 127 0.07 1.7e-13 7.1 7.0 2.9e-12 0.92 0.02 0.98 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma KIF2A 0.05 0.02 blup 71 0.02 5.4e-06 7.1 7.1 1.0e-12 0.85 0.01 0.99 FALSE
6 The Cancer Genome Atlas Esophageal Carcinoma IPO11 0.14 0.01 lasso 12 0.01 1.1e-01 7.1 7.2 6.5e-13 0.98 0.02 0.86 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IPO11 0.07 0.02 enet 11 0.05 2.3e-06 6.9 5.7 9.6e-09 0.70 0.19 0.77 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DIMT1L 0.26 0.13 lasso 1 0.10 2.3e-06 6.9 6.9 4.2e-12 0.92 0.01 0.99 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma IPO11 0.04 0.03 enet 23 0.02 2.6e-03 7.1 5.6 2.8e-08 0.69 0.02 0.88 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma IPO11 0.06 0.03 lasso 3 0.03 4.2e-04 7.1 6.7 1.6e-11 0.96 0.02 0.93 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma KIF2A 0.06 0.02 lasso 1 0.01 3.9e-02 7.1 7.1 1.2e-12 0.92 0.01 0.88 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DIMT1L 0.06 0.01 blup 53 0.03 7.2e-05 6.9 5.4 8.2e-08 0.80 0.01 0.91 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO11 0.08 0.04 blup 127 0.05 4.2e-06 7.1 6.9 4.6e-12 0.98 0.02 0.98 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIF2A 0.05 0.03 lasso 2 0.02 1.7e-03 7.1 7.0 2.4e-12 0.92 0.01 0.96 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma IPO11 0.03 0.00 blup 127 0.01 3.0e-02 7.1 6.9 5.8e-12 0.83 0.02 0.56 FALSE
16 The Cancer Genome Atlas Rectum Adenocarcinoma DIMT1L 0.33 0.15 lasso 6 0.13 6.0e-04 7.0 6.6 5.2e-11 0.96 0.01 0.81 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma IPO11 0.08 0.01 lasso 5 0.04 1.3e-03 5.9 7.2 4.4e-13 0.85 0.02 0.75 FALSE
18 The Cancer Genome Atlas Stomach Adenocarcinoma IPO11 0.14 0.05 lasso 3 0.03 1.6e-03 7.1 7.5 6.6e-14 0.91 0.02 0.95 TRUE