TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Schizophrenia (2014)
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chr3:63,121,945-64,546,545
Best TWAS P=9.12e-10 · Best GWAS P=1.54e-09 conditioned to 1
63.2M
63.4M
63.6M
63.8M
64M
64.2M
64.4M
64.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
THOC7
0.10
0.10
lasso
5
0.06
2.7e-08
6.0
-6.1
9.1e-10
-1.00
0.00
1.00
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
THOC7
0.18
0.15
bslmm
599
0.16
2.1e-20
6.0
-5.4
7.7e-08
-0.91
0.00
1.00
FALSE
2
GTEx
Brain Cerebellum
THOC7
0.27
0.10
lasso
3
0.12
1.9e-04
5.7
-5.3
1.4e-07
-0.76
0.02
0.93
FALSE