[Hub]/) : Traits : Schizophrenia (2014) :

chr3:51,616,334-53,778,875

Best TWAS P=4.12e-11 · Best GWAS P=6.31e-10 conditioned to 0.232

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RP5-966M1.6 0.11 0.07 lasso 5 0.05 6.6e-03 -5.0 -5.2 1.7e-07 0.56 0.24 0.19 FALSE
2 GTEx Artery Aorta TMEM110 0.19 0.08 enet 16 0.10 6.0e-06 -5.1 -5.2 2.4e-07 0.63 0.69 0.28 FALSE
3 GTEx Artery Aorta ITIH4-AS1 0.38 0.45 lasso 10 0.42 1.4e-24 -5.1 -5.1 3.0e-07 0.56 0.73 0.27 FALSE
4 GTEx Artery Tibial GNL3 0.08 0.06 lasso 3 0.06 3.0e-05 5.6 5.9 3.3e-09 -0.87 0.13 0.86 FALSE
5 GTEx Artery Tibial GLYCTK 0.04 0.02 enet 4 0.01 4.9e-02 5.4 5.5 3.5e-08 -0.68 0.07 0.79 FALSE
6 GTEx Brain Cerebellum GNL3 0.14 0.07 enet 43 0.09 1.3e-03 -4.5 5.7 1.4e-08 -0.81 0.24 0.63 FALSE
7 GTEx Brain Cerebellum GLYCTK 0.15 0.10 lasso 12 0.11 3.2e-04 5.5 -5.6 2.4e-08 0.62 0.05 0.89 FALSE
8 GTEx Brain Cerebellum GLYCTK-AS1 0.09 0.14 lasso 8 0.12 1.6e-04 5.5 -5.5 3.9e-08 0.63 0.06 0.64 FALSE
9 GTEx Brain Nucleus accumbens basal ganglia TMEM110 0.13 0.07 lasso 3 0.05 1.5e-02 -4.8 -5.3 8.6e-08 0.64 0.14 0.10 FALSE
10 GTEx Breast Mammary Tissue NEK4 0.06 0.03 enet 7 0.06 7.8e-04 4.9 5.5 2.9e-08 -0.76 0.06 0.79 FALSE
11 GTEx Breast Mammary Tissue NT5DC2 0.13 0.12 enet 11 0.08 9.9e-05 6.1 6.4 2.0e-10 -0.92 0.01 0.98 FALSE
12 GTEx Breast Mammary Tissue (Female) NEK4 0.02 -0.01 lasso 2 0.01 1.4e-01 5.6 5.5 2.8e-08 -0.63 0.04 0.19 FALSE
13 GTEx Breast Mammary Tissue (Female) NT5DC2 0.09 0.08 lasso 1 0.06 5.9e-03 6.1 6.1 1.2e-09 -0.96 0.02 0.79 FALSE
14 GTEx Cells EBV-transformed lymphocytes ITIH4-AS1 0.11 0.05 enet 10 0.02 5.1e-02 6.1 -6.6 4.1e-11 0.84 0.03 0.88 TRUE
15 GTEx Cells EBV-transformed lymphocytes RP5-966M1.6 0.16 0.07 enet 19 0.11 1.8e-04 -5.4 -6.3 3.0e-10 0.89 0.04 0.95 FALSE
16 GTEx Cells Transformed fibroblasts NEK4 0.07 0.11 lasso 5 0.08 7.2e-07 4.8 5.7 1.0e-08 -0.88 0.12 0.88 FALSE
17 GTEx Colon Sigmoid NT5DC2 0.08 0.07 enet 8 0.06 4.5e-03 4.4 5.3 1.2e-07 -0.90 0.04 0.84 FALSE
18 GTEx Colon Transverse ITIH4-AS1 0.20 0.03 lasso 4 0.05 2.4e-03 -5.0 -5.4 5.8e-08 0.52 0.30 0.15 FALSE
19 GTEx Esophagus Mucosa NEK4 0.05 0.03 lasso 8 0.02 2.4e-02 5.4 5.5 3.7e-08 -0.80 0.14 0.80 FALSE
20 GTEx Esophagus Mucosa GLYCTK 0.11 0.11 lasso 3 0.10 3.8e-07 5.4 5.5 4.2e-08 -0.63 0.05 0.95 FALSE
21 GTEx Esophagus Muscularis NEK4 0.06 0.00 lasso 3 0.02 2.8e-02 5.6 6.0 2.8e-09 -0.78 0.15 0.70 FALSE
22 GTEx Esophagus Muscularis GNL3 0.06 0.12 lasso 1 0.10 1.5e-06 5.6 5.6 2.1e-08 -0.90 0.08 0.92 FALSE
23 GTEx Esophagus Muscularis GLYCTK 0.09 0.10 lasso 4 0.08 9.7e-06 5.5 5.3 9.7e-08 -0.70 0.09 0.91 FALSE
24 GTEx Lung GLYCTK 0.12 0.09 lasso 6 0.08 1.5e-06 5.5 6.3 4.0e-10 -0.73 0.04 0.96 FALSE
25 GTEx Lung TMEM110 0.13 0.10 lasso 7 0.07 8.4e-06 -4.9 -5.2 1.8e-07 0.58 0.81 0.19 FALSE
26 GTEx Lung ITIH4-AS1 0.32 0.26 lasso 6 0.26 8.0e-20 -5.0 -5.5 3.4e-08 0.56 0.73 0.27 FALSE
27 GTEx Lung GLYCTK-AS1 0.11 0.09 lasso 5 0.09 3.0e-07 5.5 6.0 1.9e-09 -0.78 0.04 0.96 FALSE
28 GTEx Muscle Skeletal ITIH4-AS1 0.06 0.03 lasso 4 0.06 2.3e-06 -4.3 -5.5 4.5e-08 0.78 0.28 0.72 FALSE
29 GTEx Pituitary SFMBT1 0.16 0.01 enet 9 0.02 1.2e-01 -4.5 -5.4 5.8e-08 0.73 0.12 0.49 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic RP5-966M1.6 0.17 0.06 lasso 5 0.04 4.2e-03 -5.0 -5.4 5.6e-08 0.49 0.46 0.17 FALSE
31 GTEx Spleen GLYCTK 0.56 0.14 enet 10 0.13 4.1e-04 5.6 5.5 3.0e-08 -0.64 0.05 0.90 FALSE
32 GTEx Spleen GLYCTK-AS1 0.32 0.08 enet 18 0.09 2.2e-03 5.6 5.3 1.4e-07 -0.61 0.06 0.79 FALSE
33 GTEx Testis NT5DC2 0.11 0.16 enet 8 0.11 1.0e-05 4.9 5.4 8.5e-08 -0.88 0.07 0.92 FALSE
34 GTEx Thyroid NEK4 0.09 0.09 lasso 4 0.10 4.1e-08 -4.5 5.2 2.2e-07 -0.81 0.44 0.56 FALSE
35 GTEx Thyroid GLYCTK 0.13 0.19 lasso 3 0.17 7.1e-13 5.5 5.5 3.1e-08 -0.64 0.04 0.96 FALSE
36 GTEx Thyroid GLYCTK-AS1 0.08 0.07 enet 10 0.08 9.7e-07 5.5 5.2 1.5e-07 -0.64 0.06 0.94 FALSE
37 GTEx Whole Blood ITIH4-AS1 0.33 0.24 lasso 7 0.25 9.7e-23 -5.0 -5.5 4.9e-08 0.57 0.72 0.28 FALSE
38 METSIM Adipose GNL3 0.04 0.06 enet 25 0.05 4.5e-08 -4.4 5.2 2.3e-07 -0.80 0.50 0.50 FALSE
39 NTR Blood TMEM110 0.02 0.01 blup 391 0.01 1.1e-04 -5.4 -5.6 2.6e-08 0.79 0.02 0.98 FALSE
40 NTR Blood WDR82 0.02 0.03 blup 325 0.03 4.9e-09 5.4 -5.4 7.3e-08 0.73 0.03 0.97 FALSE
41 ROSMAP Brain Pre-frontal Cortex NEK4 0.04 0.05 blup 359 0.05 1.1e-06 5.6 6.2 4.5e-10 -0.88 0.07 0.93 FALSE
42 ROSMAP Brain Pre-frontal Cortex GNL3 0.15 0.23 enet 16 0.22 2.0e-28 5.6 6.0 2.5e-09 -0.90 0.09 0.91 FALSE
43 ROSMAP Brain Pre-frontal Cortex GLYCTK 0.05 0.08 lasso 5 0.08 2.5e-10 5.4 5.4 6.5e-08 -0.63 0.05 0.95 FALSE
44 ROSMAP Brain Pre-frontal Cortex TMEM110 0.02 0.01 blup 321 0.02 9.7e-04 -5.1 -5.6 1.7e-08 0.86 0.09 0.77 FALSE
45 YFS Blood GLYCTK 0.15 0.14 enet 17 0.13 1.1e-41 5.5 5.5 4.8e-08 -0.62 0.05 0.95 FALSE
46 YFS Blood GNL3 0.02 0.03 enet 11 0.03 2.9e-09 -4.8 5.9 3.7e-09 -0.85 0.40 0.60 FALSE
47 YFS Blood PPM1M 0.07 0.06 lasso 4 0.07 3.8e-22 5.5 5.3 8.6e-08 -0.60 0.03 0.97 FALSE
48 The Cancer Genome Atlas Bladder Urothelial Carcinoma ITIH4 0.04 0.03 blup 53 0.03 7.4e-04 -5.1 -6.1 8.3e-10 0.82 0.04 0.85 FALSE
49 The Cancer Genome Atlas Breast Invasive Carcinoma GLT8D1 0.10 0.01 enet 7 0.03 4.4e-06 -2.2 -5.7 1.0e-08 0.68 0.00 0.84 FALSE
50 The Cancer Genome Atlas Breast Invasive Carcinoma SPCS1 0.08 0.04 lasso 2 0.04 4.7e-08 5.6 -5.7 1.6e-08 0.90 0.00 1.00 FALSE
51 The Cancer Genome Atlas Colon Adenocarcinoma ITIH4 0.08 0.09 blup 53 0.08 3.1e-05 -4.9 -5.6 2.3e-08 0.64 0.34 0.53 FALSE
52 The Cancer Genome Atlas Glioblastoma Multiforme ITIH4 0.10 0.02 blup 53 0.05 1.2e-02 -5.1 -5.3 1.2e-07 0.68 0.04 0.22 FALSE
53 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ITIH4 0.04 0.02 blup 53 0.03 3.0e-04 -4.7 -5.2 1.7e-07 0.79 0.20 0.43 FALSE
54 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ITIH4 0.23 0.01 enet 7 0.02 1.6e-02 -4.6 -6.2 4.5e-10 0.69 0.03 0.95 FALSE
55 The Cancer Genome Atlas Brain Lower Grade Glioma ITIH4 0.17 0.16 lasso 5 0.14 3.1e-15 -5.1 -5.3 9.0e-08 0.59 0.64 0.36 FALSE
56 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM110 0.13 0.06 blup 59 0.08 3.3e-09 -5.4 -5.5 3.3e-08 0.80 0.08 0.92 FALSE
57 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ITIH4 0.14 0.08 lasso 3 0.10 7.0e-12 -5.4 -5.7 1.5e-08 0.71 0.10 0.90 FALSE
58 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SPCS1 0.04 0.03 enet 1 0.03 2.9e-04 5.6 -5.6 2.1e-08 0.90 0.00 0.91 FALSE
59 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ITIH4 0.05 0.02 blup 53 0.02 1.1e-02 -5.0 -6.1 1.3e-09 0.75 0.06 0.44 FALSE
60 The Cancer Genome Atlas Rectum Adenocarcinoma ITIH4 0.12 0.09 blup 53 0.06 1.4e-02 -4.7 -5.7 1.5e-08 0.85 0.03 0.54 FALSE
61 The Cancer Genome Atlas Soft Tissue Sarcoma ITIH4 0.03 0.03 lasso 4 0.03 5.1e-03 -5.4 -5.5 4.1e-08 0.75 0.03 0.57 FALSE
62 The Cancer Genome Atlas Thyroid Carcinoma ITIH4 0.20 0.12 enet 8 0.16 6.0e-15 -5.0 -5.7 1.5e-08 0.50 0.70 0.30 FALSE
63 The Cancer Genome Atlas Thyroid Carcinoma PBRM1 0.15 0.14 enet 9 0.16 7.0e-15 6.0 -5.8 7.0e-09 0.85 0.00 1.00 FALSE