Best TWAS P=1.41e-09 · Best GWAS P=6.85e-10 conditioned to 0.0305
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | ATG13 | 0.10 | 0.00 | lasso | 3 | 0.00 | 3.7e-01 | 6.2 | -5.2 | 1.9e-07 | -0.88 | 0.02 | 0.70 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | LRP4 | 0.68 | 0.00 | lasso | 10 | 0.00 | 5.0e-01 | -4.1 | -5.9 | 4.2e-09 | -0.67 | 0.03 | 0.16 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | ATG13 | 0.13 | 0.07 | enet | 16 | 0.07 | 2.1e-03 | 6.0 | -6.1 | 1.4e-09 | -0.81 | 0.04 | 0.78 | TRUE |
| 4 | GTEx | Esophagus Muscularis | ATG13 | 0.12 | 0.08 | enet | 16 | 0.04 | 1.2e-03 | 6.1 | -5.9 | 4.8e-09 | -0.93 | 0.03 | 0.96 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | ATG13 | 0.12 | 0.07 | lasso | 5 | 0.06 | 3.3e-04 | 5.7 | -5.2 | 2.2e-07 | -0.94 | 0.04 | 0.95 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | ATG13 | 0.08 | 0.05 | lasso | 4 | 0.05 | 5.1e-05 | 6.2 | -5.8 | 6.3e-09 | -0.96 | 0.03 | 0.96 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MDK | 0.03 | 0.02 | lasso | 3 | 0.02 | 2.3e-03 | 6.1 | -5.9 | 3.2e-09 | -0.94 | 0.01 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | HARBI1 | 0.05 | 0.02 | blup | 12 | 0.02 | 1.5e-02 | 5.8 | 5.4 | 6.4e-08 | 0.96 | 0.01 | 0.76 | FALSE |