Best TWAS P=1.73e-11 · Best GWAS P=4.61e-14 conditioned to 0.000495
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | NAT2 | 0.06 | 0.00 | blup | 92 | 0.02 | 0.00980 | 4.6 | -5.6 | 2.1e-08 | -0.64 | 0.04 | 0.12 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NAT2 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.00024 | 5.4 | -5.4 | 6.6e-08 | -0.63 | 0.25 | 0.40 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NAT2 | 0.03 | 0.01 | lasso | 2 | 0.01 | 0.02340 | 6.6 | -6.7 | 1.7e-11 | -0.84 | 0.05 | 0.62 | TRUE |