Best TWAS P=2.07e-105 · Best GWAS P=1.5e-115 conditioned to 1.49e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LPL | 0.09 | 0.00 | bslmm | 668 | 0.02 | 1.0e-03 | -22 | 15.5 | 2.8e-54 | -0.62 | 0.04 | 0.86 | FALSE |
| 2 | METSIM | Adipose | LZTS1 | 0.06 | 0.01 | bslmm | 639 | 0.01 | 2.9e-03 | -1 | -5.7 | 9.2e-09 | 0.18 | 0.16 | 0.04 | TRUE |
| 3 | NTR | Blood | LPL | 0.08 | 0.05 | bslmm | 667 | 0.06 | 5.5e-20 | -18 | -17.8 | 4.4e-71 | 0.91 | 0.02 | 0.98 | FALSE |
| 4 | YFS | Blood | LPL | 0.06 | 0.07 | lasso | 2 | 0.06 | 6.5e-20 | -21 | -20.5 | 8.2e-94 | 0.89 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LPL | 0.03 | 0.00 | blup | 88 | 0.00 | 1.3e-01 | -12 | -21.8 | 2.1e-105 | 0.67 | 0.07 | 0.14 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LPL | 0.09 | 0.12 | lasso | 4 | 0.11 | 3.5e-12 | -22 | 21.5 | 1.6e-102 | -0.59 | 1.00 | 0.00 | TRUE |