Best TWAS P=1.75e-08 · Best GWAS P=3.26e-11 conditioned to 0.000173
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LCMT2 | 0.19 | 0.05 | enet | 19 | 0.05 | 3.1e-05 | 4.8 | -5.2 | 1.6e-07 | -0.50 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Artery Tibial | LCMT2 | 0.25 | 0.03 | enet | 33 | 0.08 | 6.5e-07 | 4.8 | -5.6 | 1.8e-08 | -0.50 | 0.02 | 0.95 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CATSPER2 | 0.04 | 0.04 | blup | 12 | 0.04 | 1.5e-09 | 4.7 | -5.3 | 1.5e-07 | -0.48 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | CKMT1A | 0.07 | 0.05 | blup | 6 | 0.05 | 2.7e-03 | 4.3 | -5.2 | 1.8e-07 | -0.51 | 0.00 | 0.51 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CKMT1A | 0.02 | 0.02 | enet | 5 | 0.01 | 2.7e-02 | 4.5 | -5.3 | 1.0e-07 | -0.49 | 0.00 | 0.47 | TRUE |