[Hub]/) : Traits : Triglycerides :

chr12:123,716,376-125,270,773

Best TWAS P=2.98e-09 · Best GWAS P=1.6e-08 conditioned to 0.45

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 -5.4 -5.9 3.0e-09 0.90 0.04 0.95 TRUE
2 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 -5.7 -5.5 4.6e-08 0.65 0.02 0.97 FALSE
3 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 -5.4 -5.3 9.6e-08 0.99 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 -5.2 -5.2 1.6e-07 0.95 0.03 0.36 FALSE
5 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 -5.3 -5.7 1.1e-08 0.96 0.02 0.94 FALSE
6 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 -5.3 -5.2 1.6e-07 0.95 0.03 0.92 FALSE
7 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 -5.2 -5.3 1.5e-07 0.99 0.02 0.98 FALSE
8 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 -4.6 -5.2 1.7e-07 0.86 0.04 0.95 FALSE
9 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 -5.7 -5.8 5.1e-09 0.99 0.02 0.98 FALSE
10 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 -5.3 -5.7 9.4e-09 0.92 0.02 0.98 FALSE
11 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 -5.5 -5.4 6.3e-08 0.99 0.03 0.97 FALSE
12 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 -5.4 -5.2 1.6e-07 0.93 0.02 0.97 FALSE
13 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 -5.4 -5.4 7.5e-08 0.94 0.03 0.94 FALSE
14 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 -5.2 5.9 4.3e-09 -0.93 0.02 0.98 FALSE
15 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 -5.3 -5.7 1.0e-08 0.78 0.02 0.96 FALSE
16 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 -5.2 -5.3 8.9e-08 0.98 0.02 0.75 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 -5.2 -5.3 9.7e-08 0.88 0.02 0.97 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 -4.7 -5.6 2.3e-08 0.90 0.03 0.69 FALSE