[Hub]/) : Traits : Triglycerides :

chr16:30,347,731-31,860,399

Best TWAS P=8.16e-09 · Best GWAS P=1.22e-07 conditioned to 0.562

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KAT8 0.06 0.07 lasso 1 0.07 3.9e-09 -5.1 5.1 2.6e-07 -0.92 0.03 0.97 FALSE
2 CommonMind Brain Pre-frontal Cortex ZNF646 0.04 0.06 lasso 7 0.04 4.5e-06 -5.3 5.4 8.7e-08 -0.97 0.02 0.98 FALSE
3 GTEx Adrenal Gland KAT8 0.11 0.06 enet 11 0.07 1.8e-03 -5.1 5.6 2.1e-08 -0.92 0.04 0.87 FALSE
4 GTEx Artery Aorta KAT8 0.23 0.20 lasso 4 0.20 2.7e-11 -5.1 5.3 1.2e-07 -0.90 0.04 0.96 FALSE
5 GTEx Brain Cerebellar Hemisphere KAT8 0.12 0.23 lasso 3 0.18 2.9e-05 -5.1 5.1 2.8e-07 -0.95 0.03 0.86 FALSE
6 GTEx Brain Cortex KAT8 0.14 0.14 lasso 3 0.10 8.9e-04 -5.5 5.7 1.2e-08 -0.91 0.02 0.89 FALSE
7 GTEx Brain Frontal Cortex BA9 KAT8 0.16 0.20 lasso 1 0.17 2.6e-05 -5.2 5.2 2.4e-07 -0.94 0.03 0.88 FALSE
8 GTEx Breast Mammary Tissue KAT8 0.23 0.14 lasso 10 0.17 4.4e-09 -5.1 5.2 2.6e-07 -0.82 0.04 0.95 FALSE
9 GTEx Esophagus Mucosa BCKDK 0.05 0.05 enet 6 0.06 8.7e-05 -5.3 -5.8 8.2e-09 0.87 0.03 0.92 TRUE
10 GTEx Liver PRSS53 0.22 0.08 lasso 5 0.11 5.5e-04 -5.4 5.5 4.3e-08 -0.92 0.02 0.90 FALSE
11 GTEx Liver VKORC1 0.22 0.20 lasso 5 0.22 1.1e-06 -5.3 5.4 7.0e-08 -0.97 0.03 0.97 FALSE
12 GTEx Liver PRSS36 0.13 0.03 enet 34 0.04 2.2e-02 4.2 5.3 1.0e-07 -0.65 0.05 0.48 FALSE
13 GTEx Ovary KAT8 0.16 0.09 lasso 4 0.06 1.2e-02 -5.1 5.2 1.7e-07 -0.89 0.04 0.77 FALSE
14 GTEx Prostate KAT8 0.19 0.09 lasso 3 0.13 3.8e-04 -5.1 5.2 1.8e-07 -0.88 0.04 0.62 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic KAT8 0.30 0.20 enet 15 0.26 1.9e-14 3.5 5.2 2.2e-07 -0.78 0.09 0.91 FALSE
16 GTEx Stomach KAT8 0.12 0.03 lasso 5 0.07 2.9e-04 3.6 5.3 1.2e-07 -0.78 0.05 0.92 FALSE
17 GTEx Thyroid KAT8 0.21 0.12 lasso 6 0.15 2.2e-11 -5.2 5.3 1.3e-07 -0.85 0.04 0.96 FALSE
18 GTEx Whole Blood HSD3B7 0.06 0.06 lasso 4 0.06 2.6e-06 -5.0 -5.2 2.4e-07 0.97 0.04 0.96 FALSE
19 GTEx Whole Blood ZNF668 0.05 0.06 lasso 3 0.06 5.9e-06 -5.2 -5.2 2.0e-07 0.89 0.04 0.96 FALSE
20 ROSMAP Brain Pre-frontal Cortex KAT8 0.13 0.16 lasso 5 0.16 4.2e-20 -5.1 5.3 1.1e-07 -0.91 0.03 0.96 FALSE
21 YFS Blood ZNF668 0.10 0.12 bslmm 232 0.12 1.5e-36 -5.3 -5.2 1.6e-07 0.97 0.03 0.97 FALSE
22 The Cancer Genome Atlas Glioblastoma Multiforme MYST1 0.18 0.07 blup 35 0.11 4.2e-04 -5.3 5.4 5.2e-08 -0.93 0.02 0.90 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZNF668 0.03 0.01 lasso 3 0.01 2.5e-02 -5.3 -5.5 3.8e-08 0.96 0.01 0.87 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma VKORC1 0.03 0.04 lasso 3 0.04 3.2e-05 -5.3 5.3 1.2e-07 -0.99 0.02 0.98 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF668 0.02 0.02 blup 32 0.02 2.9e-03 -5.2 -5.4 6.0e-08 0.95 0.01 0.93 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma MYST1 0.16 0.08 blup 34 0.12 1.5e-13 -5.1 5.4 5.6e-08 -0.80 0.02 0.98 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF668 0.02 0.01 enet 8 0.02 3.1e-03 -5.3 -5.1 2.9e-07 0.90 0.02 0.81 FALSE
28 The Cancer Genome Atlas Liver Hepatocellular Carcinoma VKORC1 0.10 0.03 enet 7 0.07 3.8e-04 -5.1 5.5 2.9e-08 -0.94 0.02 0.96 FALSE
29 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MYST1 0.03 0.05 blup 34 0.03 2.1e-03 -5.3 5.4 5.1e-08 -0.94 0.02 0.92 FALSE
30 The Cancer Genome Atlas Pancreatic Adenocarcinoma MYST1 0.22 0.15 blup 36 0.21 2.1e-09 -5.2 5.6 1.6e-08 -0.85 0.02 0.98 FALSE
31 The Cancer Genome Atlas Rectum Adenocarcinoma MYST1 0.13 0.05 blup 35 0.06 1.9e-02 -5.2 5.4 6.2e-08 -0.92 0.01 0.61 FALSE
32 The Cancer Genome Atlas Testicular Germ Cell Tumors MYST1 0.13 0.06 blup 34 0.12 6.8e-05 -5.1 5.4 8.4e-08 -0.91 0.02 0.94 FALSE