Best TWAS P=8.32e-08 · Best GWAS P=7.83e-08 conditioned to 0.233
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | NCOA6 | 0.10 | 0.08 | lasso | 14 | 0.05 | 7.7e-03 | -4.5 | -5.1 | 2.7e-07 | 0.79 | 0.04 | 0.86 | FALSE |
| 2 | GTEx | Thyroid | TP53INP2 | 0.09 | 0.05 | lasso | 7 | 0.04 | 3.7e-04 | -4.7 | 5.4 | 8.3e-08 | -0.91 | 0.03 | 0.97 | TRUE |
| 3 | YFS | Blood | TP53INP2 | 0.02 | 0.02 | lasso | 15 | 0.01 | 1.3e-05 | -5.3 | 5.3 | 1.2e-07 | -0.86 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | NCOA6 | 0.06 | 0.03 | lasso | 1 | 0.02 | 2.0e-02 | -5.2 | -5.2 | 1.6e-07 | 0.84 | 0.02 | 0.81 | FALSE |