[Hub]/) : Traits : Triglycerides :

chr20:43,766,067-45,235,570

Best TWAS P=2.28e-11 · Best GWAS P=4.69e-18 conditioned to 0.496

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NEURL2 0.20 0.06 lasso 3 0.06 4.2e-04 8.7 -6.4 1.4e-10 -0.87 0.00 0.98 FALSE
2 GTEx Artery Coronary PLTP 0.34 0.07 lasso 5 0.10 2.6e-04 7.2 -6.7 2.3e-11 -0.68 0.02 0.87 TRUE
3 GTEx Brain Cerebellar Hemisphere SNX21 0.41 0.09 enet 16 0.05 2.1e-02 4.9 5.8 5.3e-09 0.47 0.06 0.39 FALSE
4 GTEx Brain Cerebellar Hemisphere RP3-337O18.9 0.18 0.00 lasso 5 0.00 4.0e-01 5.5 -5.2 2.4e-07 -0.46 0.10 0.31 FALSE
5 GTEx Nerve Tibial PLTP 0.11 0.01 enet 27 0.01 4.6e-02 3.8 -6.6 3.3e-11 -0.53 0.04 0.78 TRUE
6 ROSMAP Brain Pre-frontal Cortex CTSA 0.15 0.06 enet 20 0.12 7.7e-15 7.2 -6.6 5.5e-11 -0.72 0.00 1.00 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme MMP9 0.25 0.16 enet 6 0.16 1.2e-05 4.9 -5.3 9.6e-08 -0.42 0.01 0.72 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLTP 0.17 0.03 blup 52 0.06 7.0e-07 8.5 -6.0 2.5e-09 -0.48 0.01 0.97 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma ZSWIM1 0.04 0.01 blup 41 0.01 9.5e-03 8.5 6.3 3.1e-10 0.62 0.01 0.63 TRUE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLTP 0.34 0.00 lasso 3 0.05 2.8e-03 8.7 -6.1 1.1e-09 -0.69 0.00 0.57 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma PLTP 0.15 0.03 blup 51 0.05 1.1e-03 8.7 -6.3 2.8e-10 -0.68 0.00 0.85 TRUE