Best TWAS P=1.04e-19 · Best GWAS P=1.14e-30 conditioned to 6.41e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PVRL2 | 0.04 | 0.01 | blup | 55 | 0.02 | 1.5e-03 | -2.5 | 5.5 | 2.8e-08 | -0.21 | 0.04 | 0.03 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | APOC1 | 0.05 | 0.00 | blup | 47 | 0.01 | 4.3e-02 | -5.7 | -9.1 | 1.0e-19 | 0.34 | 0.01 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | APOE | 0.06 | 0.00 | blup | 49 | 0.01 | 4.5e-02 | -5.7 | -7.7 | 1.8e-14 | 0.30 | 0.02 | 0.16 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | APOE | 0.12 | 0.05 | blup | 47 | 0.07 | 9.5e-06 | 5.2 | 7.8 | 7.2e-15 | -0.36 | 0.18 | 0.44 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TOMM40 | 0.08 | 0.07 | enet | 13 | 0.07 | 2.2e-07 | 1.8 | -5.1 | 3.1e-07 | 0.53 | 0.89 | 0.11 | TRUE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | APOC4 | 0.13 | 0.10 | blup | 34 | 0.13 | 3.2e-08 | 4.0 | 6.1 | 8.4e-10 | -0.06 | 0.96 | 0.00 | TRUE |
| 7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | APOC2 | 0.20 | 0.14 | enet | 10 | 0.14 | 7.9e-05 | 4.8 | -8.5 | 1.8e-17 | 0.36 | 0.10 | 0.38 | FALSE |