Best TWAS P=1.68e-07 · Best GWAS P=3.82e-08 conditioned to 0.0542
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | PLA2G6 | 0.23 | 0.09 | lasso | 9 | 0.10 | 9.9e-08 | -5.2 | -5.2 | 1.8e-07 | 0.82 | 0.04 | 0.96 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | BAIAP2L2 | 0.09 | 0.09 | lasso | 4 | 0.09 | 5.5e-08 | -4.9 | 5.2 | 1.7e-07 | -0.87 | 0.03 | 0.97 | TRUE |