Best TWAS P=2.61e-16 · Best GWAS P=4.05e-13 conditioned to 0.114
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | GPR35 | 0.27 | 0.02 | enet | 17 | 0.08 | 2.6e-03 | 6.9 | 5.1 | 3.0e-07 | 0.60 | 0.04 | 0.36 | FALSE |
| 2 | GTEx | Nerve Tibial | CAPN10 | 0.25 | 0.07 | lasso | 10 | 0.13 | 3.1e-09 | -7.2 | -5.9 | 3.7e-09 | -0.27 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Stomach | CAPN10 | 0.20 | 0.08 | lasso | 4 | 0.12 | 1.5e-06 | 2.9 | -5.1 | 2.8e-07 | -0.22 | 0.30 | 0.11 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PP14571 | 0.05 | 0.02 | enet | 13 | 0.02 | 5.8e-06 | -4.2 | -5.4 | 6.8e-08 | -0.07 | 0.00 | 0.91 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GPR35 | 0.05 | 0.01 | blup | 66 | 0.03 | 3.9e-04 | 6.9 | 8.2 | 2.6e-16 | 0.71 | 0.00 | 0.89 | TRUE |