583 significantly associated models · 156 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 1781220 | 3261925 | 7 | 2 | 1.9e-11 | 2.1e-11 | 6.7e-01 | 100 | LOC115110 RP3-395M20.9 |
2 | 1 | 7314655 | 8738937 | 2 | 1 | 6.4e-10 | 3.4e-11 | 1.3e-02 | 86 | ERRFI1 |
3 | 1 | 19515061 | 21114833 | 2 | 4 | 1.9e-31 | 3.0e-42 | 1.5e-01 | 99 | OTUD3 PLA2G5 |
4 | 1 | 67357596 | 67972435 | 1 | 1 | 1.4e-09 | 2.0e-41 | 5.8e-38 | 9 | IL23R |
5 | 1 | 154473660 | 155862966 | 1 | 1 | 2.4e-07 | 1.7e-07 | 1.0e+00 | 100 | THBS3 |
6 | 1 | 160851894 | 162630958 | 4 | 1 | 1.9e-19 | 2.2e-21 | 1.1e-06 | 74 | FCGR2A |
7 | 1 | 200014178 | 201528243 | 2 | 1 | 7.1e-12 | 4.3e-16 | 1.6e-07 | 58 | CAMSAP1L1 |
8 | 2 | 60466491 | 62460013 | 8 | 2 | 2.4e-18 | 4.3e-23 | 1.6e-04 | 85 | PEX13 PUS10 |
9 | 2 | 199443880 | 201021954 | 1 | 1 | 1.4e-12 | 9.8e-13 | 1.0e+00 | 100 | SATB2 |
10 | 2 | 240827284 | 242265313 | 3 | 2 | 2.6e-16 | 4.0e-13 | 1.1e-01 | 95 | GPR35 PP14571 |
11 | 3 | 47884239 | 50932324 | 37 | 2 | 8.8e-20 | 2.2e-21 | 1.0e+00 | 100 | FAM212A PRKAR2A |
12 | 4 | 74173715 | 75555721 | 1 | 1 | 1.8e-07 | 2.2e-07 | 1.0e+00 | 100 | CXCL5 |
13 | 4 | 122842267 | 123530993 | 1 | 1 | 2.1e-08 | 1.5e-07 | 1.7e-02 | 79 | KIAA1109 |
14 | 5 | 12225 | 1390349 | 5 | 1 | 4.8e-11 | 3.1e-09 | 1.7e-01 | 95 | EXOC3 |
15 | 5 | 158501850 | 159005439 | 1 | 1 | 5.3e-17 | 1.1e-18 | 2.9e-03 | 89 | IL12B |
16 | 5 | 176043333 | 177426530 | 2 | 1 | 2.1e-08 | 4.5e-08 | 5.3e-01 | 99 | RGS14 |
17 | 6 | 110883139 | 112621834 | 3 | 2 | 7.6e-09 | 4.5e-11 | 9.3e-03 | 84 | C6orf3 KIAA1919 |
18 | 7 | 2032803 | 3581391 | 2 | 1 | 2.6e-10 | 3.9e-11 | 4.9e-02 | 91 | AMZ1 |
19 | 7 | 72674074 | 73952169 | 3 | 1 | 5.2e-08 | 3.9e-07 | 8.7e-01 | 100 | WBSCR26 |
20 | 7 | 106847492 | 108340749 | 4 | 1 | 6.0e-20 | 4.1e-21 | 3.6e-04 | 86 | DLD |
21 | 7 | 127878155 | 129393341 | 2 | 1 | 1.8e-10 | 3.2e-10 | 1.0e+00 | 100 | IRF5 |
22 | 9 | 4287179 | 6472714 | 4 | 2 | 1.2e-13 | 6.8e-17 | 4.1e-03 | 88 | CD274 IGHEP2 |
23 | 9 | 116849447 | 118266112 | 1 | 1 | 9.3e-12 | 5.9e-15 | 5.1e-05 | 73 | TNFSF15 |
24 | 9 | 138558883 | 140142299 | 7 | 3 | 4.9e-16 | 1.4e-16 | 1.0e+00 | 100 | CARD9 RP11-611D20.2 |
25 | 11 | 1613255 | 2161858 | 2 | 1 | 1.8e-08 | 1.4e-07 | 1.0e+00 | 100 | LSP1 |
26 | 11 | 75678647 | 77069746 | 1 | 1 | 9.9e-08 | 5.3e-14 | 4.0e-08 | 47 | LRRC32 |
27 | 12 | 67971319 | 69424500 | 1 | 1 | 4.5e-08 | 1.3e-31 | 1.2e-25 | 20 | MDM1 |
28 | 15 | 41006523 | 42468786 | 1 | 1 | 2.1e-07 | 2.2e-07 | 1.0e+00 | 100 | RTF1 |
29 | 16 | 23149956 | 24929475 | 1 | 1 | 4.2e-08 | 1.8e-08 | 6.8e-02 | 90 | PRKCB |
30 | 16 | 27691641 | 29595483 | 9 | 1 | 6.5e-08 | 4.2e-07 | 8.5e-01 | 100 | SULT1A1 |
31 | 16 | 29790709 | 31224521 | 1 | 1 | 2.4e-07 | 6.9e-07 | 1.2e-01 | 90 | ITGAL |
32 | 16 | 67872251 | 69294770 | 1 | 1 | 1.5e-08 | 3.8e-08 | 1.0e+00 | 100 | ZFP90 |
33 | 17 | 37083464 | 39502398 | 15 | 2 | 3.9e-17 | 7.2e-18 | 3.9e-02 | 94 | RAPGEFL1 SMARCE1 |
34 | 17 | 39863901 | 41538783 | 5 | 2 | 1.0e-09 | 2.0e-11 | 4.3e-01 | 99 | HSD17B1P1 PTRF |
35 | 20 | 61576647 | 62912463 | 9 | 2 | 1.3e-12 | 3.0e-11 | 5.8e-01 | 99 | RGS19 STMN3 |
36 | 21 | 45398656 | 45902320 | 1 | 1 | 3.4e-12 | 1.8e-13 | 4.8e-04 | 78 | ICOSLG |
37 | 22 | 34997079 | 36433816 | 2 | 1 | 2.5e-07 | 4.5e-07 | 1.0e+00 | 100 | TOM1 |
38 | 22 | 39064209 | 40479448 | 1 | 1 | 1.2e-09 | 3.1e-10 | 1.5e-05 | 53 | SYNGR1 |
39 | 22 | 49656585 | 51055900 | 1 | 1 | 3.1e-09 | 1.5e-10 | 1.0e+00 | 100 | PIM3 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Whole Blood | 15 | 0.75 | 2.2 |
GTEx | Brain Frontal Cortex BA9 | 7 | 0.76 | 2.1 |
GTEx | Ovary | 3 | 0.33 | 2.1 |
GTEx | Spleen | 11 | 0.78 | 2.1 |
GTEx | Adipose Visceral Omentum | 6 | 0.29 | 2.0 |
GTEx | Adrenal Gland | 5 | 0.34 | 2.0 |
GTEx | Artery Coronary | 5 | 0.42 | 2.0 |
GTEx | Brain Cerebellar Hemisphere | 12 | 0.81 | 2.0 |
GTEx | Brain Hypothalamus | 3 | 0.51 | 2.0 |
GTEx | Cells EBV-transformed lymphocytes | 5 | 0.35 | 2.0 |
GTEx | Colon Sigmoid | 8 | 0.55 | 2.0 |
GTEx | Esophagus Gastroesophageal Junction | 5 | 0.35 | 2.0 |
GTEx | Esophagus Mucosa | 15 | 0.45 | 2.0 |
GTEx | Esophagus Muscularis | 18 | 0.56 | 2.0 |
GTEx | Heart Atrial Appendage | 11 | 0.70 | 2.0 |
GTEx | Lung | 11 | 0.38 | 2.0 |
GTEx | Pancreas | 7 | 0.43 | 2.0 |
GTEx | Prostate | 3 | 0.36 | 2.0 |
GTEx | Skin Not Sun Exposed Suprapubic | 8 | 0.33 | 2.0 |
GTEx | Skin Sun Exposed Lower leg | 16 | 0.44 | 2.0 |
GTEx | Stomach | 8 | 0.55 | 2.0 |
GTEx | Uterus | 4 | 0.71 | 2.0 |
GTEx | Vagina | 1 | 0.16 | 2.0 |
NTR | Blood | 14 | 0.58 | 2.0 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 9 | 0.54 | 2.0 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 4 | 0.58 | 2.0 |
GTEx | Adipose Subcutaneous | 7 | 0.20 | 1.9 |
GTEx | Artery Aorta | 7 | 0.24 | 1.9 |
GTEx | Artery Tibial | 15 | 0.40 | 1.9 |
GTEx | Brain Caudate basal ganglia | 3 | 0.33 | 1.9 |
GTEx | Brain Cerebellum | 9 | 0.45 | 1.9 |
GTEx | Brain Cortex | 4 | 0.39 | 1.9 |
GTEx | Brain Nucleus accumbens basal ganglia | 2 | 0.23 | 1.9 |
GTEx | Brain Putamen basal ganglia | 2 | 0.32 | 1.9 |
GTEx | Breast Mammary Tissue | 5 | 0.25 | 1.9 |
GTEx | Breast Mammary Tissue (Female) | 3 | 0.18 | 1.9 |
GTEx | Cells Transformed fibroblasts | 12 | 0.29 | 1.9 |
GTEx | Colon Transverse | 6 | 0.29 | 1.9 |
GTEx | Heart Left Ventricle | 5 | 0.33 | 1.9 |
GTEx | Muscle Skeletal | 8 | 0.28 | 1.9 |
GTEx | Nerve Tibial | 15 | 0.35 | 1.9 |
GTEx | Pituitary | 4 | 0.36 | 1.9 |
GTEx | Testis | 12 | 0.38 | 1.9 |
GTEx | Thyroid | 12 | 0.30 | 1.9 |
METSIM | Adipose | 14 | 0.30 | 1.9 |
ROSMAP | Brain Pre-frontal Cortex | 17 | 0.39 | 1.9 |
YFS | Blood | 24 | 0.52 | 1.9 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 6 | 0.29 | 1.9 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 2 | 0.20 | 1.9 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 9 | 0.33 | 1.9 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 9 | 0.44 | 1.9 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 12 | 0.41 | 1.9 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.19 | 1.9 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.00 | 1.9 |
GTEx | Brain Hippocampus | 1 | 0.19 | 1.8 |
GTEx | Breast Mammary Tissue (Male) | 3 | 0.25 | 1.8 |
GTEx | Liver | 2 | 0.28 | 1.8 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.22 | 1.8 |
CommonMind | Brain Pre-frontal Cortex | 14 | 0.26 | 1.8 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 7 | 0.42 | 1.8 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 13 | 0.29 | 1.8 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.18 | 1.8 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 9 | 0.36 | 1.8 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 7 | 0.44 | 1.8 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 7 | 0.53 | 1.8 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 2 | 0.19 | 1.8 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 7 | 0.42 | 1.8 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 6 | 0.47 | 1.8 |
The Cancer Genome Atlas | Thyroid Carcinoma | 21 | 0.41 | 1.8 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.15 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 9 | 0.22 | 1.7 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 13 | 0.30 | 1.7 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 3 | 0.27 | 1.7 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 16 | 0.35 | 1.7 |