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chr17:36,211,659-37,605,364

Best TWAS P=8.09e-11 · Best GWAS P=4.88e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP4	joint
13	GTEx	Skin Sun Exposed Lower leg	PCGF2	0.36	0.30	lasso	7	0.32	1.3e-26	6.2	6.5	8.1e-11	0.97	1.00	TRUE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	PCGF2	0.23	0.23	lasso	3	0.22	9.8e-13	6.2	6.2	5.1e-10	0.99	1.00	FALSE
6	GTEx	Colon Transverse	PCGF2	0.29	0.21	lasso	5	0.20	6.2e-10	6.2	6.2	5.7e-10	1.00	1.00	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	PCGF2	0.39	0.23	lasso	4	0.21	6.9e-12	6.2	6.2	6.2e-10	1.00	1.00	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCGF2	0.06	0.06	blup	37	0.05	4.4e-11	6.2	6.2	6.7e-10	0.85	1.00	FALSE
7	GTEx	Esophagus Mucosa	PCGF2	0.32	0.24	lasso	7	0.23	1.8e-15	6.2	6.2	6.8e-10	0.97	1.00	FALSE
4	GTEx	Brain Cerebellum	PCGF2	0.25	0.29	lasso	3	0.26	2.4e-08	6.1	-6.2	6.9e-10	-0.83	1.00	FALSE
9	GTEx	Heart Atrial Appendage	PCGF2	0.18	0.13	lasso	3	0.09	6.1e-05	6.2	6.2	7.2e-10	1.00	1.00	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PCGF2	0.28	0.16	lasso	4	0.13	3.4e-06	6.2	6.1	8.0e-10	0.97	1.00	FALSE
1	GTEx	Adipose Subcutaneous	PCGF2	0.14	0.12	lasso	2	0.12	6.1e-10	6.2	6.1	1.1e-09	0.98	1.00	FALSE
3	GTEx	Artery Tibial	PCGF2	0.38	0.27	lasso	8	0.31	4.3e-25	6.2	6.0	2.6e-09	0.95	1.00	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PCGF2	0.24	0.15	lasso	5	0.18	2.2e-19	6.2	5.9	3.0e-09	0.93	1.00	FALSE
11	GTEx	Pancreas	PCGF2	0.29	0.12	lasso	5	0.07	5.3e-04	6.2	5.9	3.2e-09	0.96	0.97	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PCGF2	0.05	0.03	lasso	3	0.04	1.0e-05	4.5	5.9	3.7e-09	0.89	1.00	FALSE
10	GTEx	Lung	PCGF2	0.25	0.17	lasso	7	0.17	4.8e-13	6.2	5.8	6.4e-09	0.97	1.00	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	PCGF2	0.18	0.14	lasso	4	0.16	2.4e-16	6.2	5.8	8.0e-09	0.94	1.00	FALSE
8	GTEx	Esophagus Muscularis	PCGF2	0.21	0.15	lasso	8	0.13	3.3e-08	6.2	5.7	9.7e-09	0.96	1.00	FALSE
14	YFS	Blood	PCGF2	0.03	0.02	enet	7	0.03	2.1e-11	6.2	5.7	1.0e-08	0.79	1.00	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CISD3	0.11	0.06	blup	33	0.04	1.9e-03	6.1	-5.7	1.3e-08	-0.78	0.98	FALSE
5	GTEx	Cells Transformed fibroblasts	PCGF2	0.34	0.28	lasso	4	0.30	3.2e-23	6.2	5.6	1.8e-08	0.94	1.00	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PCGF2	0.14	0.06	blup	35	0.11	1.1e-09	6.1	5.6	2.1e-08	0.82	1.00	FALSE
2	GTEx	Adrenal Gland	PCGF2	0.34	0.09	lasso	6	0.11	8.5e-05	6.2	5.6	2.4e-08	0.87	0.98	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	PCGF2	0.27	0.22	enet	9	0.25	1.4e-24	6.2	5.6	2.5e-08	0.88	1.00	FALSE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	PCGF2	0.14	0.04	enet	8	0.16	6.8e-12	-2.3	5.5	4.4e-08	0.76	1.00	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PCGF2	0.13	0.06	blup	37	0.09	7.0e-10	6.2	5.4	5.8e-08	0.85	1.00	FALSE