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chr17:36,211,659-37,605,364

Best TWAS P=8.09e-11 · Best GWAS P=4.88e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PCGF2 0.14 0.12 lasso 2 0.12 6.1e-10 6.2 6.1 1.1e-09 0.98 0 1.00 FALSE
2 GTEx Adrenal Gland PCGF2 0.34 0.09 lasso 6 0.11 8.5e-05 6.2 5.6 2.4e-08 0.87 0 0.98 FALSE
3 GTEx Artery Tibial PCGF2 0.38 0.27 lasso 8 0.31 4.3e-25 6.2 6.0 2.6e-09 0.95 0 1.00 FALSE
4 GTEx Brain Cerebellum PCGF2 0.25 0.29 lasso 3 0.26 2.4e-08 6.1 -6.2 6.9e-10 -0.83 0 1.00 FALSE
5 GTEx Cells Transformed fibroblasts PCGF2 0.34 0.28 lasso 4 0.30 3.2e-23 6.2 5.6 1.8e-08 0.94 0 1.00 FALSE
6 GTEx Colon Transverse PCGF2 0.29 0.21 lasso 5 0.20 6.2e-10 6.2 6.2 5.7e-10 1.00 0 1.00 FALSE
7 GTEx Esophagus Mucosa PCGF2 0.32 0.24 lasso 7 0.23 1.8e-15 6.2 6.2 6.8e-10 0.97 0 1.00 FALSE
8 GTEx Esophagus Muscularis PCGF2 0.21 0.15 lasso 8 0.13 3.3e-08 6.2 5.7 9.7e-09 0.96 0 1.00 FALSE
9 GTEx Heart Atrial Appendage PCGF2 0.18 0.13 lasso 3 0.09 6.1e-05 6.2 6.2 7.2e-10 1.00 0 1.00 FALSE
10 GTEx Lung PCGF2 0.25 0.17 lasso 7 0.17 4.8e-13 6.2 5.8 6.4e-09 0.97 0 1.00 FALSE
11 GTEx Pancreas PCGF2 0.29 0.12 lasso 5 0.07 5.3e-04 6.2 5.9 3.2e-09 0.96 0 0.97 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic PCGF2 0.39 0.23 lasso 4 0.21 6.9e-12 6.2 6.2 6.2e-10 1.00 0 1.00 FALSE
13 GTEx Skin Sun Exposed Lower leg PCGF2 0.36 0.30 lasso 7 0.32 1.3e-26 6.2 6.5 8.1e-11 0.97 0 1.00 TRUE
14 YFS Blood PCGF2 0.03 0.02 enet 7 0.03 2.1e-11 6.2 5.7 1.0e-08 0.79 0 1.00 FALSE
15 The Cancer Genome Atlas Bladder Urothelial Carcinoma PCGF2 0.14 0.06 blup 35 0.11 1.1e-09 6.1 5.6 2.1e-08 0.82 0 1.00 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma PCGF2 0.06 0.06 blup 37 0.05 4.4e-11 6.2 6.2 6.7e-10 0.85 0 1.00 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma PCGF2 0.23 0.23 lasso 3 0.22 9.8e-13 6.2 6.2 5.1e-10 0.99 0 1.00 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PCGF2 0.13 0.06 blup 37 0.09 7.0e-10 6.2 5.4 5.8e-08 0.85 0 1.00 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PCGF2 0.24 0.15 lasso 5 0.18 2.2e-19 6.2 5.9 3.0e-09 0.93 0 1.00 FALSE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PCGF2 0.05 0.03 lasso 3 0.04 1.0e-05 4.5 5.9 3.7e-09 0.89 0 1.00 FALSE
21 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CISD3 0.11 0.06 blup 33 0.04 1.9e-03 6.1 -5.7 1.3e-08 -0.78 0 0.98 FALSE
22 The Cancer Genome Atlas Pancreatic Adenocarcinoma PCGF2 0.28 0.16 lasso 4 0.13 3.4e-06 6.2 6.1 8.0e-10 0.97 0 1.00 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma PCGF2 0.18 0.14 lasso 4 0.16 2.4e-16 6.2 5.8 8.0e-09 0.94 0 1.00 FALSE
24 The Cancer Genome Atlas Stomach Adenocarcinoma PCGF2 0.14 0.04 enet 8 0.16 6.8e-12 -2.3 5.5 4.4e-08 0.76 0 1.00 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma PCGF2 0.27 0.22 enet 9 0.25 1.4e-24 6.2 5.6 2.5e-08 0.88 0 1.00 FALSE