Hub : Traits :

Pulse rate, automated reading

2151 significantly associated models · 506 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 5611729 7016109 2 1 2.6e-11 9.0e-18 6.2e-08 60 ICMT
2 1 25615377 26988026 3 1 2.0e-08 1.8e-09 2.8e-02 87 SLC30A2
3 1 28011854 29594563 3 1 6.1e-09 1.6e-08 3.5e-02 86 SNHG12
4 1 39258674 40737589 5 1 1.8e-11 5.8e-09 2.3e-01 96 BMP8A
5 1 44779991 46844530 6 2 1.5e-09 2.3e-42 6.2e-40 6 GPBP1L1 ZSWIM5
6 1 66304567 67938108 3 2 2.0e-17 5.0e-25 8.5e-09 69 SGIP1 TCTEX1D1
7 1 71163715 73435171 1 1 2.4e-08 9.4e-09 4.9e-04 63 NEGR1
8 1 87215608 87884808 1 1 1.0e-07 1.2e-08 5.5e-08 9 LOC339524
9 1 155739430 157406190 2 2 8.1e-09 3.4e-12 1.2e-03 78 MEF2D MRPL24
10 1 173331762 175860452 3 2 1.7e-11 3.3e-09 3.8e-01 98 ANKRD45 KIAA0040
11 1 201099275 202607593 4 1 2.2e-10 3.9e-09 9.2e-01 100 IPO9
12 1 206802184 208664733 3 2 1.6e-18 2.1e-51 1.4e-30 42 CD34 CD55
13 1 236170665 237625236 1 1 5.1e-12 2.8e-07 1.4e-01 92 ACTN2
14 2 16998604 18537483 3 1 1.4e-19 1.2e-15 3.9e-01 99 RAD51AP2
15 2 26653457 28414302 16 1 7.5e-29 1.2e-27 1.0e+00 100 FNDC4
16 2 47224927 48727280 1 1 5.8e-11 8.8e-10 8.9e-02 92 MSH6
17 2 53583159 54976770 1 1 1.6e-07 3.8e-08 4.9e-02 87 HMGB1P31
18 2 64168232 65573478 1 1 2.2e-07 5.6e-06 8.7e-03 67 SERTAD2
19 2 135972093 137435625 2 1 3.7e-08 3.0e-08 1.0e+00 100 DARS
20 2 159577307 160334363 1 1 7.0e-09 2.4e-14 6.8e-07 58 TANC1
21 2 178280031 180379917 9 10 6.2e-20 2.4e-117 NaN NaN AC009948.5 FKBP7 OSBPL6 PRKRA RBM45 RP11-171I2.5 TTN TTN-AS1
22 2 187360440 189122229 3 1 2.2e-24 2.5e-24 1.0e+00 100 CALCRL
23 2 190357442 192254289 6 1 6.4e-12 4.5e-11 2.9e-02 89 TMEM194B
24 2 200134004 202036478 2 1 1.9e-09 8.6e-13 7.9e-05 70 C2orf47
25 2 219403022 221058583 6 3 2.3e-18 1.0e-29 3.3e-11 66 DES OBSL1 RP11-316O14.1
26 2 227498520 228912778 1 1 1.6e-13 4.8e-12 7.3e-01 100 MFF
27 2 231564626 234168951 5 3 7.5e-22 3.2e-23 1.0e+00 100 B3GNT7 EFHD1
28 3 14781364 16261420 5 1 6.5e-11 3.9e-10 1.5e-04 63 EAF1-AS1
29 3 40537829 41986787 1 1 5.5e-08 5.9e-08 1.1e-01 91 CTNNB1
30 3 46919379 51077419 46 7 1.4e-28 1.5e-26 NaN NaN AMT CSPG5 MST1 RBM6 TRAIP
31 3 51306844 54077726 15 12 1.1e-15 4.9e-17 NaN NaN DCP1A GLT8D1 GNL3 NEK4 RFT1 RP11-155D18.12 TKT TMEM110
32 3 65739897 67250048 1 1 1.1e-08 8.4e-11 1.7e-03 76 LRIG1
33 3 121346656 122929314 5 2 8.1e-14 2.9e-14 1.0e+00 100 CSTA WDR5B
34 3 140350567 141867638 1 1 2.4e-16 3.9e-17 1.0e+00 100 ZBTB38
35 3 156300190 157010086 1 1 7.8e-08 7.9e-08 1.4e-07 4 LEKR1
36 3 171513388 172365832 1 1 4.2e-08 3.3e-21 3.9e-22 -5 FNDC3B
37 3 178356269 179864765 4 1 4.4e-25 4.3e-25 1.0e+00 100 AC007620.3
38 3 182942402 184700426 4 1 9.6e-10 3.3e-12 2.0e-05 62 PSMD2
39 4 507001 2058475 7 1 5.1e-10 4.8e-12 1.6e-03 79 LOC100130872
40 4 5575751 7002344 1 1 8.5e-09 4.1e-10 2.7e-03 77 WFS1
41 4 77938810 79439935 1 1 7.8e-08 1.1e-05 2.1e-01 92 CNOT6L
42 4 82578407 83991529 1 1 1.5e-07 2.1e-09 3.8e-03 77 HNRNPD
43 4 158997448 160525502 1 1 3.6e-11 6.3e-11 1.0e+00 100 FNIP2
44 5 44129083 45516364 2 1 4.5e-08 2.9e-08 1.0e-01 91 RP11-53O19.3
45 5 74731732 75253311 1 1 8.1e-08 8.2e-09 7.2e-03 78 POC5
46 5 86867897 88427942 1 1 2.0e-09 1.1e-09 9.4e-02 92 TMEM161B-AS1
47 5 122045488 123432250 3 1 6.5e-14 1.2e-13 3.2e-01 98 CEP120
48 5 136262454 139475611 11 10 3.9e-30 3.9e-30 1.0e+00 100 CDC25C DNAJC18 HNRNPA0 MYOT REEP2 RP11-381K20.5
49 5 171876084 173289036 2 2 1.2e-10 1.2e-16 1.5e-10 40 ATP6V0E1 BNIP1
50 6 6701209 8115492 2 1 2.3e-17 4.5e-14 5.6e-02 94 DSP
51 6 25296606 26689223 1 1 1.7e-07 6.7e-11 2.3e-06 48 U91328.19
52 6 33856903 35549670 3 1 2.0e-11 2.8e-10 1.0e+00 100 C6orf106
53 6 36014161 37590303 3 2 1.1e-13 5.5e-23 2.1e-10 59 PPIL1
54 6 41058968 42587818 2 1 6.2e-09 1.8e-14 4.2e-12 18 MED20
55 6 53184508 54821152 2 1 9.8e-12 1.7e-13 1.6e-03 82 C6orf142
56 6 105033213 106549398 1 1 8.1e-09 2.0e-09 1.0e+00 100 PREP
57 6 118089396 120041948 5 5 2.3e-56 5.1e-74 3.1e-05 95 C6orf204 MCM9 RP11-351A11.1
58 6 120704438 122457698 3 6 2.3e-46 7.6e-109 4.0e-10 92 C6orf170 GJA1 TBC1D32
59 6 133961374 134468561 1 1 1.2e-16 1.4e-16 5.6e-03 89 TCF21
60 7 34711663 35471882 2 1 6.1e-13 7.6e-13 2.1e-02 90 DPY19L2P1
61 7 75059331 75803132 1 1 1.9e-07 1.8e-06 1.0e+00 100 POM121C
62 7 93345774 93883599 1 1 2.0e-07 3.4e-29 4.5e-24 19 BET1
63 7 98244565 101185166 45 14 1.8e-82 4.7e-76 NaN NaN AP4M1 ARPC1A CYP3A5 GATS GIGYF1 MEPCE PPP1R35 TFR2 TRIM56 ZKSCAN5
64 7 115619298 117135212 1 1 6.2e-13 1.2e-13 1.0e+00 100 MET
65 7 122624770 124081532 4 1 6.1e-13 4.0e-14 1.0e+00 100 WASL
66 7 130101373 131880252 2 1 9.1e-12 9.7e-25 1.6e-14 44 MKLN1-AS2
67 7 134650544 136074356 4 1 9.1e-10 7.8e-09 1.0e+00 100 SLC13A4
68 9 16448628 18201083 1 1 2.2e-07 9.4e-07 1.0e-01 89 CNTLN
69 9 35213538 36597142 2 1 2.8e-15 2.9e-15 1.0e+00 100 LINC00961
70 9 98302535 99734369 3 1 1.8e-07 1.1e-07 1.7e-02 80 HSD17B3
71 9 122669622 124303632 4 1 9.8e-10 1.5e-09 3.7e-01 98 RP11-27I1.4
72 9 127035761 129422783 3 1 1.8e-24 3.4e-25 7.0e-04 89 MAPKAP1
73 10 29001607 30716397 2 1 4.2e-12 3.4e-14 1.1e-16 -20 SVIL
74 10 42607692 43946295 1 1 2.7e-07 1.1e-09 8.6e-04 70 AL022344.7
75 10 49667361 51094660 1 1 7.0e-08 5.8e-09 4.9e-05 51 C10orf128
76 10 62920670 63459183 1 1 1.3e-08 2.2e-12 3.8e-05 66 TMEM26
77 10 74714177 76323150 10 1 5.3e-12 2.4e-10 9.0e-03 83 FUT11
78 10 100679684 103018321 8 3 6.3e-12 4.4e-12 7.2e-03 85 NDUFB8 SEC31B SLC25A28
79 10 112157994 112846298 1 1 9.9e-11 2.9e-11 6.2e-03 83 RBM20
80 10 114740745 116183647 1 1 2.7e-11 1.9e-10 3.6e-02 89 CASP7
81 11 10089027 10577397 1 1 6.1e-08 3.1e-07 8.3e-01 100 ADM
82 11 13288698 14975818 1 1 2.9e-12 9.1e-12 1.0e+00 100 SPON1
83 11 32168691 32702734 1 1 2.0e-07 1.3e-11 1.2e-07 39 WT1
84 11 47305669 48783497 1 1 2.8e-07 2.8e-07 2.4e-03 65 PTPRJ
85 11 56742853 58166421 1 1 1.4e-07 7.6e-07 7.3e-01 100 ZDHHC5
86 11 60465487 63110149 17 3 5.2e-38 1.3e-38 2.6e-02 97 EML3 FADS1 TMEM216
87 11 63295034 66184140 5 2 1.1e-09 1.7e-09 1.4e-03 72 FKBP2 RNASEH2C
88 11 77231939 78828001 1 1 5.2e-08 1.2e-07 1.0e+00 100 GAB2
89 11 101404645 102797829 1 1 2.2e-09 2.2e-09 1.0e+00 100 RP11-864G5.3
90 11 122700789 123312063 1 1 7.5e-08 1.7e-07 5.7e-01 99 ASAM
91 12 19826892 21533355 1 1 3.6e-09 3.8e-15 4.6e-08 52 PDE3A
92 12 24273423 27168878 3 2 1.1e-15 1.3e-80 2.2e-74 8 BCAT1 SSPN
93 12 27234999 28643213 4 1 3.3e-11 7.7e-11 8.7e-02 93 LOC100133893
94 12 32831091 34826574 2 5 1.9e-35 4.0e-65 NaN NaN ALG10 SYT10
95 12 38044044 39998144 2 1 4.5e-17 7.0e-19 9.4e-04 86 ALG10B
96 12 48605088 50364707 8 1 1.2e-11 1.6e-08 9.9e-02 92 RP11-302B13.5
97 12 64762194 65335717 1 1 1.5e-13 1.8e-26 4.7e-15 46 RASSF3
98 12 80954858 82853038 1 1 2.5e-12 4.0e-12 1.0e+00 100 PPFIA2
99 12 109591369 111699146 9 1 8.2e-12 1.4e-11 1.0e+00 100 GPN3
100 12 122318723 124162750 3 1 2.3e-12 9.9e-11 3.0e-04 69 ABCB9
101 13 41092698 42640341 2 1 2.8e-08 4.1e-08 1.0e+00 100 NAA16
102 14 20843889 22255090 1 1 9.3e-19 6.4e-32 1.3e-18 44 ARHGEF40
103 14 22670975 25605046 16 12 7.1e-79 4.0e-169 2.9e-34 81 CBLN3 CMTM5 HOMEZ NGDN PSMB5 RBM23 RP11-66N24.4 SLC22A17 SLC7A8 THTPA
104 14 51775331 53232305 1 1 1.6e-07 1.7e-08 4.1e-03 74 NID2
105 14 77570478 79097679 1 1 1.3e-09 5.1e-10 9.1e-03 82 ADCK1
106 14 85303548 86791228 1 1 5.5e-50 3.1e-50 1.0e+00 100 FLRT2
107 14 90643934 92390620 2 1 4.1e-13 1.6e-15 4.0e-09 46 C14orf159
108 14 101850676 103494612 2 1 7.2e-08 9.7e-09 1.7e-02 83 ZNF839
109 15 62636766 64056437 2 1 8.5e-09 1.6e-08 8.8e-02 91 LACTB
110 15 71418503 74291976 7 10 6.1e-49 3.9e-59 0.0e+00 -537 HCN4 HEXA MYO9A NEO1 NR2E3 RP11-1006G14.4
111 15 83167559 84434423 2 1 2.4e-10 9.9e-09 1.2e-03 68 BTBD1
112 15 98944630 100367846 2 1 1.6e-07 3.6e-07 1.8e-01 93 RP11-6O2.4
113 16 86671 934180 1 1 2.7e-07 4.9e-05 7.6e-01 99 LA16c-OS12.2
114 16 3608256 5479168 3 2 9.4e-08 5.4e-10 5.1e-09 11 NUDT16L1 RP11-95P2.1
115 16 15369019 16832414 1 1 7.2e-08 1.8e-30 3.7e-26 15 ABCC1
116 16 29905882 31860399 7 1 4.4e-10 4.7e-09 9.0e-01 100 RNF40
117 16 52772129 54235440 2 1 8.3e-16 3.0e-14 9.4e-01 100 RBL2
118 16 66143181 68210165 2 2 6.4e-09 2.8e-09 2.8e-03 75 ATP6V0D1 NAE1
119 16 69354963 69975360 1 1 2.8e-07 3.3e-09 2.6e-03 74 NFAT5
120 17 4156620 5556453 2 1 4.2e-08 5.9e-07 8.9e-01 100 INCA1
121 17 14509122 16109675 3 1 5.9e-14 4.4e-12 4.4e-09 28 TEKT3
122 17 16419425 18325085 9 2 5.1e-13 4.1e-12 8.3e-01 100 FLCN SREBF1
123 17 26716917 28172357 1 1 9.1e-08 8.3e-08 1.0e+00 100 MYO18A
124 17 36211659 37605364 2 1 8.1e-11 4.9e-10 1.0e+00 100 PCGF2
125 17 44788310 45876022 2 1 4.7e-09 1.7e-11 7.2e-04 75 GOSR2
126 17 73972187 75405078 3 1 4.7e-09 6.4e-10 1.0e+00 100 MXRA7
127 19 35807727 37300554 3 1 4.8e-10 4.7e-08 4.0e-02 86 CLIP3
128 19 38444944 39951086 4 1 2.4e-16 5.1e-17 1.0e-02 91 ACTN4
129 19 40000075 41953928 4 3 1.6e-13 1.8e-14 2.8e-01 98 C19orf47 C19orf54
130 20 35835657 37654024 4 5 9.9e-51 4.1e-116 2.3e-17 86 KIAA1755 TGM2 VSTM2L
131 20 39114404 40516054 1 1 1.6e-07 1.9e-11 9.1e-06 56 RP3-511B24.6
132 20 60781573 62912463 2 2 3.4e-09 2.7e-10 3.2e-04 68 PRPF6 TCFL5
133 22 38192452 40338284 16 6 2.5e-20 2.9e-20 1.0e+00 100 AL021707.1 CBX6 CBY1 GTPBP1 RP3-508I15.9 SUN2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.24 1 0 0.0 0.00 1.0e+00 NEK4
Bipolar Disorder or Schizophrenia 1.49 6 5 11.1 0.76 4.9e-02 EFHD1 GIGYF1 GLT8D1 NEK4 REEP2 RP11-53O19.3
Depressed Affect (Nagel 2018) 1.27 6 0 0.0 -0.49 3.2e-01 AL021707.1 CBY1 MST1 RBM6 RP3-508I15.9 SUN2
Depression (Nagel 2018) 1.24 1 1 2.2 0.00 1.0e+00 ZDHHC5
Intelligence (Savage-Jansen 2018) 1.50 11 6 13.3 -0.51 9.0e-02 AMT CTNNB1 HSD17B3 MST1 NEGR1 NEK4 RBL2 RBM6 RP11-302B13.5 SREBF1 ZDHHC5
Neuroticism (Nagel 2018) 1.08 2 1 2.2 0.00 1.0e+00 TMEM161B-AS1 ZDHHC5
Schizophrenia (2018) 1.42 7 1 2.2 0.89 7.1e-03 EFHD1 GIGYF1 GLT8D1 NEK4 REEP2 RP11-53O19.3 SREBF1
Worry (Nagel 2018) 1.18 2 1 2.2 0.00 1.0e+00 GLT8D1 NEK4
Alzheimer’s Disease (including proxy) 1.05 2 0 0.0 0.00 1.0e+00 GATS RNF40
Crohns Disease (2017) 1.47 7 4 8.9 0.45 2.7e-01 FADS1 FNDC4 FUT11 MST1 RBM6 RFT1 ZBTB38
Irritable Bowel Disease (IBD) 1.45 6 3 6.7 -0.10 8.1e-01 AMT FNDC4 GIGYF1 MST1 RBM6 TCTEX1D1
Ulcerative Colitis (UC) 1.26 4 3 6.7 -0.73 1.6e-01 AMT MST1 RBM6 TCTEX1D1
Major Depression (MDD) 1.58 2 1 2.2 0.00 1.0e+00 NEGR1 ZDHHC5
Reaction Time 1.38 7 0 0.0 -0.36 4.3e-01 ALG10 C2orf47 FKBP2 LA16c-OS12.2 MXRA7 RP11-302B13.5 SREBF1
Verbal and Numeric Reasoning (VNR) 1.46 7 5 11.1 -0.52 1.9e-01 MST1 NEGR1 NEK4 RAD51AP2 RBL2 RBM6 SREBF1
Breast Cancer 1.21 3 2 4.4 0.00 1.0e+00 ADM RP11-53O19.3 ZBTB38
Age at First Birth 1.49 3 1 2.2 0.00 1.0e+00 MST1 RBM6 TMEM110
Bipolar Disorder (2011) 1.72 2 1 2.2 0.00 1.0e+00 NEK4 RP11-302B13.5
Body Mass Index (BMI) (2010) 1.50 3 1 2.2 0.00 1.0e+00 NEGR1 POM121C PSMD2
Coronary Artery Disease (CAD) 1.41 2 0 0.0 0.00 1.0e+00 SREBF1 TCF21
Crohns Disease (2012) 1.38 3 2 4.4 0.96 4.0e-02 FADS1 MST1 RBM6
Fasting Glucose 1.74 3 2 4.4 0.00 1.0e+00 FADS1 FNDC4 RP3-511B24.6
HDL Cholesterol 1.85 8 4 8.9 -0.43 2.5e-01 BMP8A C6orf106 FADS1 GNL3 LACTB PDE3A PTPRJ RBM6
LDL Cholesterol 1.32 5 2 4.4 0.08 9.0e-01 C6orf106 DARS FADS1 POC5 TMEM216
Lupus 0.87 1 0 0.0 0.00 1.0e+00 TMEM194B
Schizophrenia (2014) 1.56 8 3 6.7 0.75 1.9e-02 EFHD1 GIGYF1 GLT8D1 NEK4 REEP2 RP11-53O19.3 SREBF1 ZDHHC5
Triglycerides 3.13 2 2 4.4 0.00 1.0e+00 FADS1 FNDC4
Ulcerative Colitis 1.26 2 2 4.4 0.00 1.0e+00 MST1 RBM6
Blood Eosinophil Count 0.81 18 9 20.0 -0.10 7.0e-01 ABCB9 AMT CDC25C CSTA DARS FADS1 GPN3 NEK4 NFAT5 PTPRJ RBM6 RNF40 SLC13A4 SLC30A2 SLC7A8 SREBF1 TRAIP ZDHHC5
Blood Platelet Count 1.54 48 36 80.0 0.39 6.1e-03 ACTN4 AL021707.1 AP4M1 ARPC1A BNIP1 C10orf128 C6orf106 CBY1 CEP120 CYP3A5 DNAJC18 FADS1 FKBP2 FNDC4 GIGYF1 GPBP1L1 GTPBP1 HSD17B3 ICMT KIAA1755 LA16c-OS12.2 LACTB MEF2D MEPCE MET MRPL24 MST1 POC5 PPP1R35 RNASEH2C RNF40 RP11-27I1.4 RP11-864G5.3 RP11-95P2.1 RP3-508I15.9 RP3-511B24.6 SERTAD2 SUN2 SVIL TFR2 TGM2 TMEM216 VSTM2L WASL WT1 ZDHHC5 ZKSCAN5 ZNF839
Blood Red Count 1.96 43 31 68.9 0.31 3.4e-02 ADM AMT ARPC1A BMP8A C6orf106 C6orf170 CDC25C DARS FADS1 FNDC4 GAB2 GATS GIGYF1 GJA1 GLT8D1 GOSR2 GPBP1L1 GPN3 HNRNPA0 LA16c-OS12.2 MAPKAP1 MED20 MFF MST1 MYO9A NEK4 NFAT5 NR2E3 PPP1R35 PSMD2 RBM6 RNASEH2C RNF40 SERTAD2 SREBF1 TFR2 TMEM110 TMEM194B TRAIP TRIM56 ZBTB38 ZDHHC5 ZKSCAN5
Blood White Count 1.16 28 21 46.7 0.05 7.7e-01 ACTN4 ARPC1A C10orf128 C19orf54 C6orf106 C6orf204 CALCRL CEP120 FADS1 FNDC3B FNDC4 GNL3 HSD17B3 INCA1 KIAA1755 MXRA7 PTPRJ RBM6 RFT1 RNF40 RP11-864G5.3 SREBF1 SVIL TCTEX1D1 TGM2 TMEM110 ZKSCAN5 ZSWIM5
Heel T-Score 1.77 43 34 75.6 0.34 1.8e-02 AL021707.1 AMT ANKRD45 BMP8A C10orf128 C6orf204 CALCRL CBX6 CBY1 CEP120 CTNNB1 EML3 FADS1 FLCN GAB2 GIGYF1 GJA1 GLT8D1 GTPBP1 LEKR1 LOC100130872 MSH6 MST1 NAE1 NEGR1 PCGF2 PTPRJ RBM6 RFT1 RNASEH2C RNF40 RP11-95P2.1 RP3-508I15.9 RP3-511B24.6 SEC31B SERTAD2 SREBF1 SUN2 TANC1 TCTEX1D1 TRAIP ZBTB38 ZDHHC5
BMI 1.94 38 26 57.8 0.35 1.9e-02 ABCB9 ANKRD45 AP4M1 ARPC1A BMP8A C14orf159 C6orf106 C6orf142 CEP120 CSPG5 CTNNB1 CYP3A5 DNAJC18 FKBP2 FNDC4 GAB2 GLT8D1 GPBP1L1 GPN3 HCN4 HEXA IPO9 MEF2D MST1 MYO9A NEGR1 NEK4 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 TMEM161B-AS1 ZKSCAN5 ZNF839
Height 2.06 72 56 124.4 -0.31 5.6e-03 ADM AMT ANKRD45 ARHGEF40 ARPC1A ATP6V0E1 B3GNT7 BNIP1 C19orf54 C6orf106 CALCRL CBLN3 CBX6 CBY1 CEP120 CMTM5 CTNNB1 DNAJC18 DPY19L2P1 EFHD1 FADS1 FNDC3B FNDC4 GAB2 GIGYF1 GJA1 GNL3 GOSR2 GPBP1L1 GTPBP1 HMGB1P31 HNRNPD HSD17B3 LA16c-OS12.2 LOC339524 MAPKAP1 MED20 MEF2D MKLN1-AS2 MRPL24 MYO9A NFAT5 NGDN NR2E3 NUDT16L1 POM121C PRPF6 PSMD2 PTPRJ RBL2 REEP2 RFT1 RNF40 RP11-171I2.5 RP11-27I1.4 RP11-316O14.1 RP11-864G5.3 RP11-95P2.1 RP3-508I15.9 SLC13A4 SLC25A28 SLC30A2 SPON1 SREBF1 SSPN SUN2 TCTEX1D1 TMEM110 ZBTB38 ZDHHC5 ZKSCAN5 ZNF839
Waist Hip Ratio (WHR) 2.26 24 20 44.4 0.30 8.5e-02 ADM ALG10 AMT C14orf159 C6orf106 CALCRL CNOT6L EML3 GLT8D1 GNL3 MEF2D NEK4 PDE3A PTPRJ RBL2 REEP2 RFT1 RNASEH2C RP11-95P2.1 SREBF1 SSPN TMEM110 TRAIP ZBTB38
Systolic Blood Pressure 1.55 33 19 42.2 -0.14 4.3e-01 C2orf47 C6orf142 CD34 CEP120 CSPG5 CSTA CTNNB1 DNAJC18 FNDC4 FUT11 GOSR2 HOMEZ MAPKAP1 MEF2D MKLN1-AS2 MST1 NAA16 NUDT16L1 POM121C PTPRJ RNASEH2C RP3-511B24.6 SEC31B SGIP1 SLC13A4 SLC22A17 SNHG12 SREBF1 TCF21 TMEM161B-AS1 TMEM194B WASL ZDHHC5
Smoking Status 1.42 7 4 8.9 -0.48 1.9e-01 AMT ARPC1A CSPG5 LA16c-OS12.2 MAPKAP1 MSH6 ZKSCAN5
Allergy or Eczema 1.12 9 4 8.9 0.25 5.2e-01 ARPC1A C6orf106 CALCRL CDC25C CYP3A5 MYOT NEGR1 SREBF1 ZBTB38
Cardiovascular Disease 1.29 11 5 11.1 0.42 2.0e-01 CSPG5 FNDC4 GOSR2 MAPKAP1 NEGR1 NFAT5 POM121C RNASEH2C RNF40 TCF21 TMEM161B-AS1
Hypothyroidism (self reported) 1.13 3 2 4.4 -0.98 2.3e-02 FADS1 GIGYF1 TMEM194B
Respiratory disease 1.06 1 1 2.2 0.00 1.0e+00 FADS1
Type 2 Diabetes (T2D) (2018) 1.70 7 6 13.3 0.08 8.7e-01 BMP8A FNDC4 LOC100133893 NFAT5 RBL2 RBM6 WFS1
Lung FEV1/FVC ratio 1.64 35 18 40.0 -0.37 2.5e-02 ADM AP4M1 ATP6V0D1 BMP8A BTBD1 C6orf106 CALCRL CEP120 DCP1A DES EML3 GAB2 GJA1 GPBP1L1 HNRNPD KIAA0040 LOC100133893 MEF2D MET MFF NEGR1 NEK4 PCGF2 RAD51AP2 RFT1 RNF40 RP11-351A11.1 RP11-53O19.3 RP11-95P2.1 SERTAD2 SREBF1 TCF21 ZBTB38 ZDHHC5 ZSWIM5
Lung FVC 1.33 24 16 35.6 -0.17 4.1e-01 ATP6V0D1 B3GNT7 BTBD1 C6orf106 C6orf204 CD55 CEP120 DARS EFHD1 EML3 GATS LA16c-OS12.2 MEF2D MSH6 NFAT5 RNASEH2C RP11-171I2.5 RP11-316O14.1 SLC30A2 SREBF1 TCF21 TMEM194B WDR5B ZBTB38
Neuroticism 1.17 4 1 2.2 -0.25 7.5e-01 GAB2 SLC22A17 TMEM161B-AS1 ZDHHC5
Chronotype (morning person) 1.72 8 4 8.9 0.74 1.5e-02 ALG10 ALG10B HNRNPD MYO9A NR2E3 REEP2 SYT10 ZDHHC5
Hair Pigment 0.32 16 8 17.8 -0.24 3.1e-01 ADM BMP8A BTBD1 EFHD1 FADS1 FNDC4 GAB2 GIGYF1 MEPCE MSH6 NEO1 REEP2 RNASEH2C RP11-302B13.5 TRIM56 ZBTB38
Tanning 0.23 5 4 8.9 -0.71 1.8e-01 FNDC4 GAB2 LEKR1 NEK4 TCTEX1D1
Hand grip strength (left) 1.34 7 3 6.7 0.13 7.8e-01 C2orf47 DARS MEPCE NFAT5 NUDT16L1 RP11-171I2.5 ZBTB38
Number of treatments/medications taken 1.30 1 1 2.2 0.00 1.0e+00 RBM6
Average weekly spirits intake 1.47 1 0 0.0 0.00 1.0e+00 MST1
Frequency of depressed mood in last 2 weeks 1.07 1 0 0.0 0.00 1.0e+00 ZDHHC5
Hearing difficulty/problems: Yes 1.12 2 0 0.0 0.00 1.0e+00 GPBP1L1 TTN-AS1
Relative age of first facial hair 1.44 6 3 6.7 -0.18 7.3e-01 C6orf106 FNDC4 MED20 MKLN1-AS2 RP11-381K20.5 ZBTB38
Systolic blood pressure, automated reading 1.46 11 2 4.4 -0.22 5.2e-01 GOSR2 MAPKAP1 MKLN1-AS2 NFAT5 POM121C RBM23 SEC31B SGIP1 SLC22A17 TMEM194B ZDHHC5
Eye problems/disorders: Diabetes related eye disease 1.13 1 0 0.0 0.00 1.0e+00 WFS1
Angina 1.17 1 1 2.2 0.00 1.0e+00 TCF21
Medication: Co-codamol 1.14 1 0 0.0 0.00 1.0e+00 ABCB9
Medication: Metformin 1.59 3 2 4.4 0.00 1.0e+00 FNDC4 RBL2 WFS1
Diabetes (father) 1.19 1 0 0.0 0.00 1.0e+00 FNDC4
Pack years adult smoking proportion 1.35 1 0 0.0 0.00 1.0e+00 AMT
Impedance of leg (right) 1.46 23 16 35.6 0.37 7.4e-02 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 FNDC4 GLT8D1 HNRNPD MED20 NEGR1 NEK4 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RP11-302B13.5 SREBF1 TMEM110 TMEM161B-AS1 VSTM2L
Leg fat-free mass (left) 2.04 30 24 53.3 -0.18 3.2e-01 ABCB9 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNF40 SLC30A2 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Trunk fat percentage 1.69 24 17 37.8 0.56 2.8e-03 ABCB9 C6orf106 C6orf142 CNOT6L CTNNB1 DARS EML3 FKBP2 HNRNPD MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP ZBTB38 ZKSCAN5
Hand grip strength (right) 1.35 9 3 6.7 -0.40 2.8e-01 C6orf106 DARS GNL3 MEPCE NFAT5 PSMD2 RFT1 RP11-171I2.5 ZBTB38
Current tobacco smoking 1.24 1 1 2.2 0.00 1.0e+00 MAPKAP1
Fed-up feelings 1.38 4 1 2.2 1.00 1.7e-04 MST1 RBM6 TMEM216 ZDHHC5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.43 1 0 0.0 0.00 1.0e+00 ZDHHC5
Relative age voice broke 1.15 2 0 0.0 0.00 1.0e+00 NFAT5 RP11-95P2.1
Taking other prescription medications 1.29 1 1 2.2 0.00 1.0e+00 RBM6
Age when periods started (menarche) 1.68 14 8 17.8 -0.52 3.1e-02 AMT GAB2 GATS GLT8D1 GNL3 MED20 MSH6 NEGR1 NEK4 NFAT5 POM121C RFT1 RNASEH2C TMEM110
Heel bone mineral density (BMD) T-score, automated (left) 1.54 9 4 8.9 0.61 8.1e-02 AMT CBY1 LEKR1 MST1 RBM6 RNASEH2C SERTAD2 SUN2 TRAIP
High blood pressure 1.21 7 1 2.2 0.50 2.5e-01 MAPKAP1 NEGR1 POM121C PTPRJ RBL2 TCF21 TMEM161B-AS1
Hayfever, allergic rhinitis or eczema 1.17 5 1 2.2 0.74 1.5e-01 C6orf106 CDC25C SREBF1 U91328.19 ZBTB38
Medication: Levothyroxine sodium 1.04 1 0 0.0 0.00 1.0e+00 FADS1
Sitting height 1.97 39 27 60.0 -0.28 6.7e-02 ADM AMT ARHGEF40 ARPC1A BMP8A C2orf47 C6orf106 CALCRL CEP120 CTNNB1 DNAJC18 EFHD1 FADS1 FNDC3B FNDC4 GNL3 GOSR2 GPBP1L1 HSD17B3 KIAA1755 LA16c-OS12.2 MAPKAP1 MED20 MYO9A NEO1 NFAT5 NUDT16L1 PSMD2 RBL2 RFT1 RP11-171I2.5 RP11-95P2.1 SLC13A4 SLC30A2 TMEM110 VSTM2L ZBTB38 ZDHHC5 ZKSCAN5
Body mass index (BMI) 1.82 26 15 33.3 0.26 1.7e-01 ABCB9 ANKRD45 ARPC1A BMP8A C14orf159 C6orf106 C6orf142 CEP120 CSPG5 DARS FKBP2 FNDC4 GPN3 IPO9 MST1 NEGR1 NEK4 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 TMEM161B-AS1 U91328.19 ZKSCAN5
Impedance of leg (left) 1.50 26 15 33.3 0.38 4.9e-02 AMT ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 FNDC4 GLT8D1 GNL3 HNRNPD MED20 NEGR1 NEK4 NFAT5 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RP11-302B13.5 SREBF1 TMEM110 TMEM161B-AS1 VSTM2L
Leg predicted mass (left) 2.04 30 24 53.3 -0.18 3.1e-01 ABCB9 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNF40 SLC30A2 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Trunk fat mass 1.88 27 16 35.6 0.40 3.4e-02 ABCB9 BMP8A C6orf106 C6orf142 CEP120 CNOT6L CTNNB1 DARS FKBP2 MST1 NEGR1 NEO1 NFAT5 NUDT16L1 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP U91328.19 ZBTB38 ZKSCAN5
Waist circumference 1.82 19 14 31.1 0.47 2.9e-02 ABCB9 ARPC1A BMP8A C6orf106 CEP120 CNOT6L CTNNB1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNASEH2C RNF40 TMEM161B-AS1 ZBTB38 ZKSCAN5
Number of incorrect matches in round 1.13 1 0 0.0 0.00 1.0e+00 IPO9
Past tobacco smoking 1.42 5 0 0.0 0.33 5.9e-01 ARPC1A CSPG5 MSH6 TMEM161B-AS1 ZKSCAN5
Alcohol usually taken with meals 1.31 3 1 2.2 0.00 1.0e+00 ANKRD45 NEGR1 ZDHHC5
Nervous feelings 1.12 1 1 2.2 0.00 1.0e+00 NEK4
Forced vital capacity (FVC) 1.44 15 10 22.2 -0.60 1.4e-02 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 FNDC3B HSD17B3 MYO9A NFAT5 NR2E3 NUDT16L1 RFT1 SLC30A2 ZBTB38
Heel bone mineral density (BMD) T-score, automated (right) 1.65 11 4 8.9 0.33 3.2e-01 ALG10 AMT ANKRD45 CBY1 LEKR1 RBM6 RNASEH2C SERTAD2 SUN2 TRAIP ZBTB38
Qualifications: None of the above 1.36 5 2 4.4 0.33 5.8e-01 AMT MST1 NEGR1 RBM6 ZDHHC5
Financial difficulties in last 2 years 1.13 1 0 0.0 0.00 1.0e+00 BMP8A
Mouth/teeth dental problems 1.04 1 0 0.0 0.00 1.0e+00 SLC13A4
Heart attack 1.31 1 0 0.0 0.00 1.0e+00 TCF21
Allergy 1.11 4 1 2.2 -0.71 2.9e-01 C6orf106 CDC25C U91328.19 ZBTB38
Diabetes (self-reported) 1.69 6 3 6.7 0.08 8.8e-01 FNDC4 LOC100133893 NFAT5 RBL2 RBM6 WFS1
Hayfever/allergic rhinitis (self-reported) 1.19 1 0 0.0 0.00 1.0e+00 CYP3A5
Medication: Simvastatin 1.18 1 1 2.2 0.00 1.0e+00 FNDC4
Fluid intelligence score 1.38 5 2 4.4 -0.67 2.2e-01 MST1 NEGR1 RBL2 RBM6 SREBF1
Neuroticism score 1.02 2 1 2.2 0.00 1.0e+00 SLC22A17 ZDHHC5
Weight 2.05 27 19 42.2 0.09 6.5e-01 ABCB9 BMP8A C14orf159 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FKBP2 FNDC4 GPN3 MED20 MST1 NEGR1 NEO1 NFAT5 NUDT16L1 POC5 POM121C PSMD2 RBM6 RFT1 RNF40 RP11-95P2.1 TMEM161B-AS1 U91328.19 ZBTB38
Impedance of arm (right) 1.61 26 15 33.3 0.58 2.1e-03 ADM AMT C2orf47 CEP120 DES DPY19L2P1 EML3 FNDC4 FNIP2 GAB2 GLT8D1 GPN3 HNRNPD NEGR1 NEK4 POC5 POM121C PSMD2 RBM6 REEP2 RP11-302B13.5 RP11-316O14.1 RP11-864G5.3 U91328.19 ZDHHC5 ZNF839
Arm fat percentage (right) 1.68 21 12 26.7 0.63 1.1e-03 ABCB9 ARPC1A BMP8A C6orf106 C6orf142 CNOT6L CTNNB1 DARS FKBP2 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-1006G14.4 TMEM161B-AS1 ZDHHC5 ZKSCAN5
Trunk fat-free mass 2.09 30 24 53.3 -0.37 3.5e-02 ABCB9 ADM ARHGEF40 B3GNT7 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GOSR2 HSD17B3 MED20 MYO9A NEK4 NUDT16L1 POC5 PRPF6 PSMD2 RBL2 RBM6 RFT1 SLC30A2 TMEM110 ZBTB38
Hip circumference 1.99 29 23 51.1 -0.13 5.1e-01 ABCB9 AL021707.1 BMP8A C14orf159 C6orf106 CBY1 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC4 GPN3 MED20 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBL2 RBM6 RNF40 RP11-95P2.1 RP3-508I15.9 SREBF1 SUN2 TMEM161B-AS1 U91328.19 ZBTB38
Alcohol intake versus 10 years previously 1.65 5 2 4.4 0.98 4.4e-03 BMP8A FNDC4 MST1 NEGR1 RBM6
Worrier / anxious feelings 1.22 2 2 4.4 0.00 1.0e+00 NEK4 ZDHHC5
Frequency of tiredness / lethargy in last 2 weeks 1.24 3 2 4.4 -0.74 2.6e-01 AMT TRAIP ZDHHC5
Forced expiratory volume in 1-second (FEV1) 1.47 18 11 24.4 -0.52 2.2e-02 AMT BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 FNDC3B HSD17B3 MYO9A NFAT5 NR2E3 PCGF2 RFT1 SLC30A2 U91328.19 ZBTB38 ZDHHC5
Pulse rate 11.96 77 40 88.9 0.99 3.5e-82 AC007620.3 AC009948.5 ACTN4 AL021707.1 ALG10 ALG10B AMT ARHGEF40 ATP6V0E1 B3GNT7 BCAT1 C6orf170 C6orf204 CALCRL CBY1 CD34 CEP120 CMTM5 CTNNB1 DCP1A DES DSP EML3 FADS1 FKBP7 FLRT2 FNDC4 FNIP2 FUT11 GIGYF1 GJA1 GTPBP1 HCN4 HOMEZ IPO9 KIAA1755 LINC00961 LOC339524 MAPKAP1 MCM9 MEPCE MFF MKLN1-AS2 MXRA7 NAA16 NEK4 NEO1 NGDN OSBPL6 POC5 PPFIA2 PPP1R35 PREP RAD51AP2 RBL2 RBM23 REEP2 RP11-171I2.5 RP11-381K20.5 RP11-66N24.4 RP3-508I15.9 SLC22A17 SPON1 SREBF1 SUN2 SVIL TBC1D32 TCF21 TCTEX1D1 TEKT3 TFR2 TGM2 THTPA TKT TRAIP VSTM2L ZBTB38
Qualifications: A levels/AS levels or equivalent 1.49 4 3 6.7 -0.32 6.0e-01 MST1 NEGR1 POM121C RBM6
Mouth/teeth dental problems: Dentures 1.25 1 0 0.0 0.00 1.0e+00 RBM6
Asthma 1.02 1 0 0.0 0.00 1.0e+00 FADS1
Medication: Cholesterol lowering 1.27 1 1 2.2 0.00 1.0e+00 FNDC4
Forced expiratory volume in 1-second (FEV1), Best measure 1.48 15 9 20.0 -0.69 2.9e-03 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 FNDC3B HSD17B3 MYO9A NFAT5 NR2E3 PCGF2 RFT1 SLC30A2 ZBTB38
Impedance of arm (left) 1.66 24 15 33.3 0.51 9.0e-03 ADM AMT C2orf47 CEP120 DES DNAJC18 DPY19L2P1 EML3 FNDC4 FNIP2 GAB2 GLT8D1 GOSR2 HNRNPD NEGR1 NEK4 POC5 POM121C PSMD2 RBM6 REEP2 RP11-316O14.1 U91328.19 ZNF839
Arm fat mass (right) 1.87 27 18 40.0 0.27 1.6e-01 ABCB9 AC007620.3 ARPC1A BMP8A C6orf106 C6orf142 CEP120 CNOT6L CTNNB1 FKBP2 FNDC4 GPN3 IPO9 MED20 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 TMEM161B-AS1 U91328.19 ZBTB38 ZKSCAN5
Trunk predicted mass 2.09 32 23 51.1 -0.38 2.6e-02 ABCB9 ADM ARHGEF40 B3GNT7 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GOSR2 GPN3 HSD17B3 MED20 MYO9A NEGR1 NEK4 NUDT16L1 POC5 PRPF6 PSMD2 RBL2 RBM6 RFT1 SLC30A2 TMEM110 ZBTB38
Standing height 1.98 42 34 75.6 -0.37 9.6e-03 AMT ARHGEF40 ATP6V0E1 B3GNT7 BNIP1 C6orf106 CBX6 CEP120 CTNNB1 DNAJC18 EFHD1 FADS1 FNDC3B FNDC4 GNL3 GPBP1L1 HMGB1P31 HNRNPD HSD17B3 LA16c-OS12.2 MAPKAP1 MED20 MYO9A NFAT5 NR2E3 NUDT16L1 PRPF6 PSMD2 PTPRJ RBL2 RFT1 RP11-171I2.5 RP11-27I1.4 RP11-316O14.1 RP11-95P2.1 RP3-508I15.9 SLC13A4 SLC25A28 SLC30A2 TMEM110 ZBTB38 ZKSCAN5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.43 2 2 4.4 0.00 1.0e+00 NEGR1 SGIP1
Hair/balding pattern: Pattern 4 1.02 6 4 8.9 -0.19 7.2e-01 ATP6V0D1 CTNNB1 FADS1 MKLN1-AS2 RP3-511B24.6 ZBTB38
Birth weight of first child 1.33 5 2 4.4 0.65 2.3e-01 POM121C RP11-864G5.3 SVIL WT1 ZBTB38
Peak expiratory flow (PEF) 1.22 4 2 4.4 0.38 6.2e-01 PCGF2 SLC30A2 TCF21 TMEM194B
Pulse wave reflection index 2.42 3 1 2.2 0.00 1.0e+00 HOMEZ KIAA1755 VSTM2L
Ever highly irritable/argumentative for 2 days 1.11 1 0 0.0 0.00 1.0e+00 RBM6
Medication: Paracetamol 1.34 1 0 0.0 0.00 1.0e+00 MEF2D
Headache pain in last month 1.38 1 1 2.2 0.00 1.0e+00 MEF2D
Medication for cholesterol, blood pressure or diabetes 1.33 2 0 0.0 0.00 1.0e+00 GATS TCF21
Gout (self-reported) 1.43 2 1 2.2 0.00 1.0e+00 FNDC4 NFAT5
Hypothyroidism/myxoedema (self-reported) 1.14 3 1 2.2 -0.97 2.8e-02 FADS1 GIGYF1 TMEM194B
Birth weight 1.26 5 2 4.4 -0.63 2.6e-01 ARHGEF40 CEP120 PSMD2 RFT1 RP11-864G5.3
Chronic bronchitis/emphysema (mother) 1.17 1 0 0.0 0.00 1.0e+00 SLC30A2
Forced vital capacity (FVC), Best measure 1.45 17 10 22.2 -0.65 3.7e-03 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 FNDC3B HSD17B3 MYO9A NFAT5 NR2E3 NUDT16L1 RFT1 RNASEH2C SLC13A4 SLC30A2 ZBTB38
Body fat percentage 1.76 26 15 33.3 0.59 6.9e-04 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 DARS EML3 FKBP2 HCN4 HNRNPD MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP U91328.19 ZBTB38 ZKSCAN5
Leg fat percentage (right) 1.89 21 15 33.3 0.53 4.9e-03 ABCB9 ARPC1A C6orf106 CNOT6L DARS GPBP1L1 HCN4 HSD17B3 MET MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 U91328.19 ZKSCAN5
Arm fat-free mass (right) 2.05 31 18 40.0 -0.28 1.2e-01 ABCB9 ARHGEF40 B3GNT7 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GOSR2 GPN3 HSD17B3 MED20 NEGR1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNASEH2C RP11-864G5.3 SLC30A2 TMEM110 U91328.19 ZBTB38
Comparative body size at age 10 1.38 6 5 11.1 -0.30 5.7e-01 ATP6V0D1 CSPG5 HNRNPD NEGR1 RNF40 RP11-302B13.5
Worry too long after embarrassment 1.18 2 1 2.2 0.00 1.0e+00 TMEM161B-AS1 ZDHHC5
Wheeze or whistling in the chest in last year 1.18 2 1 2.2 0.00 1.0e+00 HSD17B3 RBM6
Age at first live birth 1.37 1 1 2.2 0.00 1.0e+00 RBM6
Qualifications: College or University degree 1.57 11 4 8.9 -0.31 3.3e-01 AMT CSPG5 DCP1A FNIP2 MST1 NEGR1 POM121C RBL2 RBM6 RP11-864G5.3 ZDHHC5
Medication for pain relief, constipation, heartburn 1.23 1 1 2.2 0.00 1.0e+00 MEF2D
Neck or shoulder pain in last month 1.13 1 0 0.0 0.00 1.0e+00 BMP8A
Medication: Blood pressure 1.29 1 0 0.0 0.00 1.0e+00 TCF21
Angina (self-reported) 1.18 1 1 2.2 0.00 1.0e+00 TCF21
Migraine (self-reported) 1.24 3 0 0.0 0.00 1.0e+00 MEF2D POC5 SVIL
Medication: Allopurinol 1.26 1 1 2.2 0.00 1.0e+00 FNDC4
Medication: Omeprazole 1.22 1 0 0.0 0.00 1.0e+00 C6orf106
Mean time to correctly identify matches 1.43 4 1 2.2 -0.03 9.7e-01 LA16c-OS12.2 MXRA7 RP11-302B13.5 SREBF1
Whole body fat mass 1.90 28 15 33.3 0.35 5.4e-02 ABCB9 ARPC1A BMP8A C6orf106 C6orf142 CEP120 CNOT6L CTNNB1 DARS DNAJC18 FKBP2 GPN3 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38 ZKSCAN5
Leg fat mass (right) 1.98 25 15 33.3 0.46 1.3e-02 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 DARS GPN3 HCN4 IPO9 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38 ZKSCAN5
Arm predicted mass (right) 2.07 30 19 42.2 -0.30 8.8e-02 ABCB9 ARHGEF40 B3GNT7 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GPN3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RP11-864G5.3 SLC30A2 TMEM110 U91328.19 ZBTB38
Alcohol intake frequency. 1.76 7 3 6.7 0.50 2.1e-01 CBY1 FNDC4 MST1 NFAT5 RBM6 SUN2 ZDHHC5
Comparative height size at age 10 1.68 25 19 42.2 -0.39 4.2e-02 ARHGEF40 B3GNT7 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GPBP1L1 HNRNPD HSD17B3 LA16c-OS12.2 MYO9A NR2E3 NUDT16L1 PRPF6 PSMD2 RBL2 RFT1 RP11-171I2.5 RP11-27I1.4 SLC13A4 SLC30A2 ZBTB38
Overall health rating 1.72 7 3 6.7 0.27 5.1e-01 C6orf106 C6orf142 FNIP2 MST1 RBL2 RBM6 ZDHHC5
Age at last live birth 1.09 1 1 2.2 0.00 1.0e+00 RBM6
Leg pain on walking 1.31 1 1 2.2 0.00 1.0e+00 RBM6
Qualifications: NVQ or HND or HNC or equivalent 1.27 1 0 0.0 0.00 1.0e+00 RBM6
Illness, injury, bereavement, stress in last 2 years 1.28 1 0 0.0 0.00 1.0e+00 BMP8A
Medication: Aspirin 1.08 1 0 0.0 0.00 1.0e+00 MEF2D
Knee pain experienced in last month 1.08 1 0 0.0 0.00 1.0e+00 RBM6
Hypertension (Self-reported) 1.21 8 1 2.2 0.55 1.6e-01 CSPG5 GATS MAPKAP1 NEGR1 POM121C PTPRJ TCF21 TMEM161B-AS1
Illnesses of father: Heart disease 1.04 1 0 0.0 0.00 1.0e+00 TCF21
Smoking status: Previous 1.47 1 0 0.0 0.00 1.0e+00 MSH6
Forced expiratory volume in 1-second (FEV1), predicted 1.56 4 2 4.4 -0.23 7.7e-01 C6orf106 MYO9A NUDT16L1 ZBTB38
Whole body fat-free mass 2.09 31 25 55.6 -0.26 1.4e-01 ABCB9 ARHGEF40 B3GNT7 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GOSR2 GPN3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PRPF6 PSMD2 RBL2 RBM6 RFT1 SLC30A2 TMEM110 ZBTB38
Leg fat-free mass (right) 2.01 32 23 51.1 -0.23 1.9e-01 ABCB9 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNF40 RP3-508I15.9 SLC13A4 SLC30A2 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Arm fat percentage (left) 1.73 21 13 28.9 0.63 1.1e-03 ABCB9 ARPC1A BMP8A C6orf106 C6orf142 CNOT6L CTNNB1 DARS FKBP2 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-1006G14.4 TMEM161B-AS1 ZDHHC5 ZKSCAN5
Average weekly red wine intake 1.27 2 1 2.2 0.00 1.0e+00 NEO1 ZDHHC5
Mood swings 1.03 1 0 0.0 0.00 1.0e+00 RBM6
Long-standing illness, disability or infirmity 1.43 3 0 0.0 0.00 1.0e+00 NEGR1 NFAT5 TMEM161B-AS1
Diabetes diagnosed by doctor 1.79 8 3 6.7 0.08 8.5e-01 AMT BMP8A FNDC4 LOC100133893 NFAT5 RBL2 RBM6 WFS1
Qualifications: nursing, teaching 1.43 3 1 2.2 0.00 1.0e+00 MST1 NEGR1 RBM6
Medication for cholesterol 1.29 1 1 2.2 0.00 1.0e+00 FNDC4
Back pain experienced in last month 1.16 1 0 0.0 0.00 1.0e+00 C6orf106
Mineral and other dietary supplements 1.60 2 0 0.0 0.00 1.0e+00 ARPC1A CYP3A5
Asthma (self-reported) 1.04 1 0 0.0 0.00 1.0e+00 FADS1
Osteoporosis (self-reported) 1.11 1 0 0.0 0.00 1.0e+00 CTNNB1
Medication: Aspirin 1.05 1 0 0.0 0.00 1.0e+00 MEF2D
Medication: Gliclazide 1.42 1 0 0.0 0.00 1.0e+00 WFS1
Smoking status: Current 1.25 2 1 2.2 0.00 1.0e+00 FNIP2 MAPKAP1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.29 7 3 6.7 -0.44 3.3e-01 BTBD1 CEP120 EML3 GJA1 NFAT5 PCGF2 SLC30A2
Whole body water mass 2.09 32 25 55.6 -0.28 1.1e-01 ABCB9 ARHGEF40 B3GNT7 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GOSR2 GPN3 HSD17B3 MED20 NEGR1 NEK4 NUDT16L1 POC5 POM121C PRPF6 PSMD2 RBL2 RBM6 RFT1 SLC30A2 TMEM110 ZBTB38
Leg predicted mass (right) 2.02 31 23 51.1 -0.20 2.7e-01 ABCB9 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNF40 SLC13A4 SLC30A2 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Arm fat mass (left) 1.89 27 19 42.2 0.35 6.0e-02 ABCB9 ARPC1A BMP8A C6orf106 CEP120 CNOT6L CTNNB1 DNAJC18 FKBP2 FNDC4 GPN3 IPO9 MED20 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 TMEM161B-AS1 U91328.19 ZBTB38 ZKSCAN5
Number of self-reported non-cancer illnesses 1.21 3 2 4.4 0.00 1.0e+00 FNDC4 NEGR1 NFAT5
Average weekly champagne plus white wine intake 1.22 1 0 0.0 0.00 1.0e+00 FADS1
Miserableness 1.25 2 1 2.2 0.00 1.0e+00 AMT RBM6
Guilty feelings 1.15 1 0 0.0 0.00 1.0e+00 ZDHHC5
Mother's age at death 1.49 1 0 0.0 0.00 1.0e+00 MAPKAP1
Eye problems/disorders: Glaucoma 1.12 1 0 0.0 0.00 1.0e+00 PTPRJ
Supplements: Fish oil (including cod liver oil) 1.49 2 0 0.0 0.00 1.0e+00 ARPC1A CYP3A5
High cholesterol (Self-reported) 1.30 2 1 2.2 0.00 1.0e+00 FNDC4 POC5
Medication: Bendroflumethiazide 1.09 1 0 0.0 0.00 1.0e+00 TCF21
Medication: Paracetamol 1.30 1 0 0.0 0.00 1.0e+00 AMT
Medication: Atorvastatin 1.42 1 1 2.2 0.00 1.0e+00 FNDC4
Ever smoked 1.46 4 2 4.4 -0.14 8.2e-01 ARPC1A CSPG5 MSH6 ZKSCAN5
Basal metabolic rate 2.09 32 25 55.6 -0.24 1.6e-01 ABCB9 ARHGEF40 BMP8A C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GPN3 HSD17B3 MED20 NEGR1 NUDT16L1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RNF40 RP11-95P2.1 SLC30A2 TMEM110 TMEM161B-AS1 U91328.19 ZBTB38
Leg fat percentage (left) 1.91 23 14 31.1 0.39 3.9e-02 ABCB9 ARPC1A C6orf106 CNOT6L DARS GPBP1L1 GPN3 HCN4 HSD17B3 MAPKAP1 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 U91328.19 ZKSCAN5
Arm fat-free mass (left) 2.05 27 17 37.8 -0.29 1.3e-01 ABCB9 ARHGEF40 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GPN3 MED20 NEGR1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RP11-864G5.3 SLC30A2 TMEM110 U91328.19 ZBTB38
Average weekly beer plus cider intake 0.98 1 0 0.0 0.00 1.0e+00 RBM6
Irritability 1.23 1 0 0.0 0.00 1.0e+00 TMEM216
Ever had prostate specific antigen (PSA) test 1.35 1 0 0.0 0.00 1.0e+00 ZBTB38
Diastolic blood pressure, automated reading 2.34 27 6 13.3 0.94 5.2e-15 ABCB9 AC007620.3 ARPC1A BNIP1 BTBD1 CEP120 CSPG5 CSTA CTNNB1 DARS GATS GIGYF1 MAPKAP1 MST1 MYO9A NR2E3 POC5 POM121C RBM6 RNF40 RP11-351A11.1 SEC31B SPON1 TMEM161B-AS1 TMEM194B TRAIP WDR5B
Vascular/heart problems diagnosed by doctor 1.24 4 1 2.2 0.44 5.6e-01 NEGR1 PTPRJ TCF21 TMEM161B-AS1
Cholesterol lowering medication 1.38 2 1 2.2 0.00 1.0e+00 CALCRL FNDC4
Pain experienced in last month 1.17 2 1 2.2 0.00 1.0e+00 BMP8A RBM6
Heart attack/myocardial infarction (self-reported) 1.30 1 0 0.0 0.00 1.0e+00 TCF21
Impedance of whole body 1.60 24 18 40.0 0.36 7.1e-02 ADM AMT BMP8A C14orf159 C2orf47 C6orf106 CBX6 CEP120 DNAJC18 EML3 FNDC4 GAB2 GLT8D1 HNRNPD NEGR1 NEK4 POC5 POM121C PSMD2 RBM6 RFT1 RP11-316O14.1 TMEM110 ZNF839
Leg fat mass (left) 1.98 28 15 33.3 0.36 4.4e-02 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 DARS DNAJC18 FKBP2 FNDC4 GPN3 HCN4 IPO9 MST1 NEGR1 NEO1 NFAT5 POC5 POM121C PSMD2 RBM6 RNF40 RP11-1006G14.4 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38 ZKSCAN5
Arm predicted mass (left) 2.04 28 16 35.6 -0.29 1.2e-01 ABCB9 ARHGEF40 BMP8A C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 EFHD1 FNDC3B FNDC4 GLT8D1 GNL3 GPN3 HSD17B3 MED20 NEGR1 POC5 POM121C PSMD2 RBL2 RBM6 RFT1 RP11-864G5.3 SLC30A2 TMEM110 U91328.19 ZBTB38

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 47 1.35 3.3
GTEx Adipose Visceral Omentum 33 1.62 3.4
GTEx Adrenal Gland 21 1.44 3.2
GTEx Artery Aorta 41 1.38 3.5
GTEx Artery Coronary 19 1.61 3.5
GTEx Artery Tibial 55 1.46 3.4
GTEx Brain Caudate basal ganglia 10 1.09 3.0
GTEx Brain Cerebellar Hemisphere 21 1.41 3.3
GTEx Brain Cerebellum 22 1.11 3.2
GTEx Brain Cortex 9 0.87 2.9
GTEx Brain Frontal Cortex BA9 10 1.08 3.0
GTEx Brain Hippocampus 2 0.38 2.6
GTEx Brain Hypothalamus 5 0.85 3.1
GTEx Brain Nucleus accumbens basal ganglia 11 1.27 3.2
GTEx Brain Putamen basal ganglia 9 1.44 4.0
GTEx Breast Mammary Tissue 31 1.57 3.3
GTEx Breast Mammary Tissue (Male) 10 0.84 3.0
GTEx Breast Mammary Tissue (Female) 24 1.46 3.3
GTEx Cells EBV-transformed lymphocytes 17 1.19 3.0
GTEx Cells Transformed fibroblasts 63 1.50 3.3
GTEx Colon Sigmoid 15 1.03 3.2
GTEx Colon Transverse 31 1.50 3.4
GTEx Esophagus Gastroesophageal Junction 26 1.80 3.5
GTEx Esophagus Mucosa 53 1.60 3.5
GTEx Esophagus Muscularis 44 1.36 3.4
GTEx Heart Atrial Appendage 32 2.03 4.6
GTEx Heart Left Ventricle 33 2.16 4.1
GTEx Liver 8 1.12 3.7
GTEx Lung 38 1.32 3.4
GTEx Muscle Skeletal 41 1.42 3.4
GTEx Nerve Tibial 76 1.76 3.7
GTEx Ovary 19 2.09 4.3
GTEx Pancreas 30 1.84 3.5
GTEx Pituitary 14 1.26 3.4
GTEx Prostate 12 1.44 3.5
GTEx Skin Not Sun Exposed Suprapubic 44 1.79 3.7
GTEx Skin Sun Exposed Lower leg 65 1.79 3.5
GTEx Small Intestine Terminal Ileum 5 1.08 3.0
GTEx Spleen 20 1.42 3.3
GTEx Stomach 24 1.65 3.5
GTEx Testis 42 1.33 3.3
GTEx Thyroid 57 1.43 3.4
GTEx Uterus 9 1.59 3.2
GTEx Vagina 14 2.20 3.5
GTEx Whole Blood 28 1.40 3.2
METSIM Adipose 50 1.08 3.0
NTR Blood 33 1.37 3.2
ROSMAP Brain Pre-frontal Cortex 58 1.32 3.3
YFS Blood 51 1.10 3.0
CommonMind Brain Pre-frontal Cortex 62 1.15 3.0
The Cancer Genome Atlas Bladder Urothelial Carcinoma 22 1.33 2.9
The Cancer Genome Atlas Breast Invasive Carcinoma 60 1.36 3.1
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 11 1.00 3.2
The Cancer Genome Atlas Colon Adenocarcinoma 29 1.40 3.3
The Cancer Genome Atlas Esophageal Carcinoma 9 1.31 2.9
The Cancer Genome Atlas Glioblastoma Multiforme 10 0.98 3.1
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 33 1.21 3.0
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 57 1.39 3.0
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 32 1.56 3.1
The Cancer Genome Atlas Brain Lower Grade Glioma 57 1.32 2.9
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 14 1.27 3.3
The Cancer Genome Atlas Lung Adenocarcinoma 42 1.43 3.0
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 21 0.84 2.9
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 20 1.26 3.0
The Cancer Genome Atlas Pancreatic Adenocarcinoma 25 1.51 3.1
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 11 0.83 3.0
The Cancer Genome Atlas Prostate Adenocarcinoma 59 1.28 3.0
The Cancer Genome Atlas Rectum Adenocarcinoma 7 1.01 3.2
The Cancer Genome Atlas Soft Tissue Sarcoma 17 1.59 3.2
The Cancer Genome Atlas Skin Cutaneous Melanoma 8 1.50 2.9
The Cancer Genome Atlas Stomach Adenocarcinoma 25 1.48 2.9
The Cancer Genome Atlas Testicular Germ Cell Tumors 15 1.17 3.3
The Cancer Genome Atlas Thyroid Carcinoma 69 1.34 3.1
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 4 0.79 3.0