Best TWAS P=4.66e-09 · Best GWAS P=6.41e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-318A15.2 | 0.26 | 0.16 | lasso | 2 | 0.17 | 6.9e-14 | 6.1 | -5.8 | 6.9e-09 | -0.94 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Muscle Skeletal | MXRA7 | 0.37 | 0.30 | enet | 24 | 0.36 | 2.7e-36 | 6.1 | -5.2 | 2.3e-07 | -0.88 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | MXRA7 | 0.40 | 0.31 | lasso | 6 | 0.36 | 7.2e-12 | 6.2 | -5.3 | 1.1e-07 | -0.92 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | JMJD6 | 0.08 | 0.09 | blup | 37 | 0.09 | 1.5e-10 | 4.1 | -5.2 | 1.5e-07 | -0.91 | 0.19 | 0.81 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MXRA7 | 0.45 | 0.51 | lasso | 5 | 0.54 | 3.5e-71 | 6.1 | -5.9 | 4.7e-09 | -0.95 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MXRA7 | 0.31 | 0.26 | lasso | 6 | 0.36 | 2.3e-21 | 6.1 | -5.5 | 3.2e-08 | -0.85 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MXRA7 | 0.15 | 0.12 | enet | 10 | 0.17 | 2.4e-19 | 6.2 | -5.2 | 2.3e-07 | -0.85 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | MXRA7 | 0.10 | 0.07 | enet | 8 | 0.08 | 1.3e-08 | 6.2 | -5.3 | 1.1e-07 | -0.87 | 0.00 | 1.00 | FALSE |