Best TWAS P=4.83e-10 · Best GWAS P=4.73e-08 conditioned to 0.0404
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CLIP3 | 0.19 | 0.02 | enet | 39 | 0.10 | 4.6e-08 | -4.2 | 5.8 | 5.8e-09 | 0.59 | 0.02 | 0.92 | FALSE |
| 2 | GTEx | Muscle Skeletal | TBCB | 0.15 | 0.00 | enet | 33 | 0.05 | 1.3e-05 | 5.0 | -6.0 | 2.5e-09 | -0.42 | 0.02 | 0.25 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | WDR62 | 0.35 | 0.08 | enet | 35 | 0.22 | 2.3e-18 | 3.0 | 6.2 | 5.5e-10 | 0.63 | 0.12 | 0.87 | FALSE |
| 4 | YFS | Blood | CLIP3 | 0.47 | 0.11 | bslmm | 324 | 0.23 | 9.4e-74 | 5.0 | 5.3 | 1.1e-07 | 0.46 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CLIP3 | 0.16 | 0.01 | enet | 12 | 0.05 | 1.3e-05 | 5.0 | 6.2 | 4.8e-10 | 0.62 | 0.01 | 0.49 | TRUE |