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chr2:135,972,093-137,435,625

Best TWAS P=3.69e-08 · Best GWAS P=2.96e-08 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	The Cancer Genome Atlas	Soft Tissue Sarcoma	DARS	0.04	0.04	blup	40	0.04	1.6e-03	-5.4	-5.5	3.7e-08	0.95	0.02	0.93	TRUE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DARS	0.08	0.10	lasso	4	0.09	8.8e-05	-5.4	-5.4	8.1e-08	0.96	0.02	0.93	FALSE
6	GTEx	Thyroid	DARS	0.20	0.13	lasso	3	0.15	1.3e-11	-5.1	-5.3	9.9e-08	0.95	0.03	0.96	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	DARS	0.15	0.11	enet	4	0.10	3.0e-06	-5.1	-5.3	1.0e-07	0.97	0.03	0.97	FALSE
4	GTEx	Nerve Tibial	DARS	0.13	0.06	lasso	5	0.05	3.2e-04	-5.4	-5.3	1.1e-07	0.95	0.02	0.96	FALSE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DARS	0.02	0.02	lasso	2	0.02	3.9e-03	-5.2	-5.3	1.2e-07	0.95	0.02	0.92	FALSE
2	GTEx	Esophagus Muscularis	DARS	0.12	0.11	lasso	3	0.09	3.5e-06	-5.1	-5.3	1.4e-07	0.94	0.02	0.98	FALSE
3	GTEx	Lung	DARS	0.07	0.05	lasso	4	0.05	5.8e-05	-5.1	-5.2	1.8e-07	0.94	0.03	0.97	FALSE
1	GTEx	Esophagus Mucosa	DARS	0.12	0.05	lasso	4	0.04	9.0e-04	-5.1	-5.2	2.2e-07	0.93	0.04	0.91	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	LCT	0.02	0.02	enet	3	0.03	7.6e-07	-4.8	5.1	3.1e-07	-0.82	0.02	0.97	FALSE