TWAS hub - DARS

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0830	0.0410	2.3e-03	0.012	NA	-0.002	NA	0.008	3.3e-02	NA	5.0e-01	NA	6.8e-02
2	GTEx	Brain Cerebellar Hemisphere	0.5170	0.1370	1.4e-03	-0.012	NA	0.039	NA	-0.007	9.6e-01	NA	3.6e-02	NA	5.5e-01
3	GTEx	Breast Mammary Tissue	0.1260	0.0570	6.1e-03	-0.003	NA	-0.006	NA	-0.004	4.7e-01	NA	9.8e-01	NA	5.8e-01
4	GTEx	Breast Mammary Tissue (Male)	0.1098	0.0997	1.7e-01	0.002	NA	0.000	NA	0.001	2.9e-01	NA	3.2e-01	NA	2.9e-01
5	GTEx	Breast Mammary Tissue (Female)	0.0592	0.0570	1.6e-01	0.048	NA	0.033	NA	0.032	1.5e-02	NA	3.7e-02	NA	3.9e-02
6	GTEx	Esophagus Mucosa	0.1200	0.0480	2.9e-04	0.050	NA	0.035	NA	0.041	2.8e-04	NA	2.0e-03	NA	9.0e-04
7	GTEx	Esophagus Muscularis	0.1220	0.0460	8.4e-05	0.110	NA	0.067	NA	0.091	3.6e-07	NA	7.0e-05	NA	3.5e-06
8	GTEx	Lung	0.0744	0.0303	7.5e-04	0.045	NA	0.027	NA	0.054	2.2e-04	NA	3.3e-03	NA	5.8e-05
9	GTEx	Nerve Tibial	0.1295	0.0549	5.9e-04	0.063	NA	0.026	NA	0.046	2.8e-05	NA	5.6e-03	NA	3.2e-04
10	GTEx	Ovary	0.2810	0.1090	1.2e-03	0.123	NA	0.098	NA	0.112	6.2e-04	NA	2.2e-03	NA	1.1e-03
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1510	0.0560	1.2e-04	0.112	NA	0.103	NA	0.101	1.1e-06	NA	3.0e-06	NA	3.5e-06
12	GTEx	Skin Sun Exposed Lower leg	0.0980	0.0390	2.9e-05	0.119	NA	0.082	NA	0.112	5.0e-10	NA	2.8e-07	NA	1.7e-09
13	GTEx	Thyroid	0.1980	0.0560	6.5e-10	0.127	NA	0.109	NA	0.151	6.6e-10	NA	1.1e-08	NA	1.3e-11
14	METSIM	Adipose	0.0892	0.0242	3.6e-11	0.067	0.088	0.080	0.087	0.083	2.8e-10	4.6e-13	5.9e-12	6.4e-13	1.8e-12
15	YFS	Blood	0.1679	0.0327	0.0e+00	0.190	0.178	0.190	0.170	0.186	8.2e-60	7.6e-56	8.2e-60	4.1e-53	1.4e-58
16	TCGA	Breast Invasive Carcinoma	0.0658	0.0293	9.3e-09	0.032	0.049	0.044	NA	0.035	3.7e-07	2.4e-10	1.9e-09	NA	8.1e-08
17	TCGA	Glioblastoma Multiforme	0.1620	0.1030	3.8e-03	0.039	0.031	0.073	NA	0.054	2.4e-02	4.1e-02	3.1e-03	NA	9.6e-03
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.0414	0.0221	1.1e-05	0.048	0.041	0.045	NA	0.049	4.2e-06	2.0e-05	8.6e-06	NA	3.5e-06
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.1029	0.0469	1.4e-11	0.085	0.094	0.106	NA	0.092	8.1e-10	1.0e-10	5.5e-12	NA	1.6e-10
20	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0930	0.0550	9.3e-05	0.074	0.064	0.049	NA	0.060	4.8e-05	1.6e-04	8.2e-04	NA	2.3e-04
21	TCGA	Lung Squamous Cell Carcinoma	0.0198	0.0123	2.7e-03	0.024	0.011	0.013	NA	0.017	8.3e-04	2.0e-02	1.1e-02	NA	3.9e-03
22	TCGA	Pancreatic Adenocarcinoma	0.0790	0.0440	7.6e-04	0.104	0.082	0.093	NA	0.095	3.9e-05	2.6e-04	9.9e-05	NA	8.8e-05
23	TCGA	Prostate Adenocarcinoma	0.0394	0.0219	2.2e-04	0.018	0.011	-0.001	NA	0.008	4.8e-03	2.0e-02	4.6e-01	NA	4.9e-02
24	TCGA	Soft Tissue Sarcoma	0.0430	0.0250	1.1e-03	0.040	0.042	0.036	NA	0.037	2.1e-03	1.6e-03	3.1e-03	NA	2.8e-03
25	TCGA	Thyroid Carcinoma	0.2150	0.1030	0.0e+00	0.154	0.176	0.189	NA	0.165	8.6e-15	7.3e-17	4.1e-18	NA	8.3e-16

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
LDL Cholesterol	8.3	13.2	19.4	3.9	3.1	0.4	3.7	4.2	4.1	4.0	4.1	0.4	4.1	4.0	4.3	2.5	4.0	2.2	3.8	4.2	3.3	3.8	4.1	4.1	4.4	4.3	4.2
Forced expiratory volume in 1-second (FEV1)	7.5	25.4	41.7	5.0	4.6	-0.9	3.8	5.7	5.6	5.6	5.7	1.1	5.8	5.5	5.8	4.7	6.5	3.3	3.2	5.4	5.7	5.3	5.8	5.8	6.2	6.0	5.7
Lung FVC	7.3	37.3	60.7	7.4	6.6	0.3	4.7	6.8	6.7	6.7	6.6	5.3	6.8	6.7	6.8	5.3	7.8	5.0	3.3	6.5	6.2	5.0	6.5	6.6	7.8	7.2	6.1
Hand grip strength (left)	7.3	19.2	28.9	5.0	2.2	0.1	1.9	5.0	5.0	5.0	5.0	1.6	5.4	5.0	5.2	4.1	5.0	4.5	3.5	4.8	5.0	4.0	5.3	4.9	5.0	5.3	4.3
Forced expiratory volume in 1-second (FEV1), Best measure	7.3	23.4	43.0	4.8	4.4	0.6	3.5	5.4	5.4	5.4	5.3	1.4	5.5	5.3	5.5	5.2	6.6	3.6	3.0	5.1	5.3	4.9	5.3	5.4	5.9	5.6	5.6
Forced vital capacity (FVC)	7.1	27.5	48.3	5.1	4.8	-0.6	3.3	5.9	5.9	5.8	6.0	0.7	6.0	5.7	6.1	4.9	7.0	3.4	3.3	5.6	5.6	5.5	6.1	6.0	6.7	6.3	5.9
Number of incorrect matches in round	6.5	10.7	16.3	4.0	0.5	0.1	1.2	4.0	4.0	4.0	3.8	2.8	3.7	4.0	3.9	2.2	3.0	3.7	3.1	3.9	3.3	2.8	3.6	3.8	3.4	3.9	3.0
Hand grip strength (right)	6.1	16.7	24.5	4.8	1.2	-0.7	0.8	4.6	4.6	4.7	4.8	1.8	5.0	4.6	4.8	3.6	4.5	4.1	3.2	4.5	4.5	4.1	4.9	4.7	4.9	4.9	4.4
Forced vital capacity (FVC), Best measure	5.9	21.6	42.1	4.5	4.2	0.4	3.1	5.3	5.2	5.1	5.1	0.9	5.2	5.0	5.3	5.2	6.5	3.7	2.4	4.9	5.0	4.6	5.1	5.2	5.9	5.3	5.3
Pulse rate, automated reading	5.8	18.7	30.2	-4.2	-1.5	1.8	-0.9	-5.2	-5.3	-5.2	-5.3	-0.7	-5.3	-5.1	-5.3	-2.8	-4.5	-3.3	-3.3	-5.1	-4.8	-4.6	-5.3	-5.4	-4.9	-5.5	-4.4
Diastolic blood pressure, automated reading	5.8	17.9	30.0	-4.0	-2.6	-0.3	-0.7	-5.0	-5.0	-5.0	-4.8	-0.9	-5.0	-5.0	-4.8	-3.6	-5.3	-4.1	-0.8	-4.9	-4.9	-4.8	-4.5	-4.8	-5.5	-4.5	-5.3
Leg fat percentage (left)	4.5	16.1	27.8	-4.4	-2.4	-0.3	-0.5	-4.8	-4.7	-4.6	-4.5	-2.2	-4.8	-4.6	-4.7	-3.6	-5.1	-2.8	-2.0	-4.7	-4.6	-3.9	-4.5	-4.5	-5.3	-4.9	-4.3
Leg fat percentage (right)	4.3	15.7	25.8	-4.3	-2.5	0.0	-1.1	-4.8	-4.7	-4.6	-4.5	-2.2	-4.8	-4.6	-4.6	-3.5	-5.0	-2.7	-2.2	-4.6	-4.4	-3.7	-4.4	-4.5	-5.1	-4.9	-4.1
Angina (self-reported)	4.3	5.7	14.1	-2.7	-1.0	-0.5	-1.3	-2.4	-2.6	-2.6	-2.7	-1.3	-2.7	-2.5	-2.5	-3.8	-2.9	-2.8	-0.6	-2.5	-2.9	-2.4	-2.4	-2.7	-2.5	-2.4	-2.5
Breast cancer (self-reported)	4.3	5.2	8.9	-2.3	-1.8	0.5	-0.8	-2.8	-2.7	-2.6	-2.5	-1.0	-2.8	-2.7	-2.7	-1.6	-2.7	-1.7	-1.4	-2.8	-2.0	-2.4	-2.5	-2.5	-3.0	-2.6	-2.6
Angina	4.1	5.3	12.3	-2.6	-0.9	-0.6	-1.4	-2.4	-2.5	-2.5	-2.7	-1.1	-2.7	-2.5	-2.4	-3.5	-2.7	-2.8	-0.8	-2.5	-2.7	-2.4	-2.4	-2.6	-2.5	-2.4	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.9	8.2	17.2	2.9	3.5	1.3	2.1	3.1	3.0	3.0	2.9	0.8	3.1	3.0	3.2	3.9	4.2	1.9	1.4	3.0	3.3	2.3	3.2	2.9	3.5	3.3	2.9
Body fat percentage	3.7	14.8	27.5	-4.6	-2.1	-0.7	-0.3	-4.6	-4.5	-4.4	-4.4	-2.6	-4.6	-4.4	-4.5	-2.8	-4.7	-2.4	-2.6	-4.4	-3.9	-3.6	-4.4	-4.4	-5.2	-4.9	-4.0
Trunk fat percentage	3.5	13.9	27.5	-4.7	-1.9	-1.2	-0.0	-4.4	-4.3	-4.2	-4.2	-3.0	-4.5	-4.2	-4.3	-2.5	-4.5	-2.5	-2.5	-4.3	-3.6	-3.4	-4.2	-4.2	-5.2	-4.7	-3.9
Alcohol intake versus 10 years previously	3.4	5.1	12.6	-2.2	-1.5	0.1	0.4	-2.5	-2.5	-2.5	-2.7	-0.4	-2.5	-2.2	-2.6	-2.1	-3.1	-0.8	-0.9	-2.2	-1.9	-2.9	-2.6	-2.9	-3.5	-2.8	-3.2
Respiratory disease	3.3	7.3	13.8	2.9	3.0	-0.5	2.6	2.9	2.8	2.8	3.0	1.1	2.8	2.6	3.0	1.3	3.2	2.1	2.2	3.2	2.6	3.1	3.0	3.1	3.7	3.0	3.4
Commuting to job workplace: Cycle	3.3	4.0	9.5	1.9	2.3	-1.2	1.3	2.2	2.2	2.1	2.1	1.0	2.1	2.0	2.1	1.0	3.1	1.8	-0.2	2.1	2.4	1.7	2.0	2.1	2.9	2.2	2.9
Leg fat mass (left)	3.3	13.1	23.6	-4.3	-2.5	-0.2	-0.6	-4.4	-4.3	-4.2	-4.1	-2.6	-4.3	-4.2	-4.2	-2.7	-4.5	-2.3	-1.8	-4.2	-4.0	-3.2	-4.0	-4.1	-4.9	-4.5	-3.6
Severe depression (siblings)	3.2	3.6	6.8	2.2	0.6	1.9	1.8	1.9	1.9	1.9	2.0	1.5	2.0	1.8	1.9	2.1	2.4	2.0	0.8	1.8	2.3	2.1	2.0	1.9	2.0	1.8	2.6
Arm fat percentage (right)	3.2	12.6	21.3	-4.1	-1.6	0.0	-0.3	-4.3	-4.2	-4.2	-4.2	-1.8	-4.3	-4.1	-4.2	-2.4	-4.2	-2.0	-2.9	-4.2	-3.7	-3.5	-4.0	-4.2	-4.6	-4.5	-3.7
Systolic blood pressure, automated reading	3.1	9.1	16.9	-2.6	-3.1	0.1	-1.8	-3.4	-3.3	-3.3	-3.2	0.0	-3.4	-3.4	-3.4	-3.4	-4.1	-2.5	-0.5	-3.2	-3.5	-3.5	-3.2	-3.2	-3.9	-3.0	-4.0
Peak expiratory flow (PEF)	3.1	7.1	16.9	3.0	4.1	-0.5	3.0	2.8	2.7	2.7	2.9	1.7	2.9	2.6	2.9	2.0	3.1	2.3	2.0	2.7	2.6	2.3	2.9	2.9	3.1	3.0	2.6
Leg fat mass (right)	3.1	12.2	21.6	-4.2	-2.5	-0.1	-0.8	-4.2	-4.1	-4.0	-4.0	-2.6	-4.2	-4.0	-4.0	-2.5	-4.3	-2.3	-1.9	-4.1	-3.8	-3.0	-3.8	-3.9	-4.7	-4.3	-3.4
Arm fat percentage (left)	3.1	12.3	20.8	-4.0	-1.6	-0.3	-0.3	-4.2	-4.2	-4.1	-4.1	-1.6	-4.3	-4.0	-4.2	-2.7	-4.2	-2.0	-2.9	-4.1	-3.6	-3.5	-4.0	-4.1	-4.6	-4.5	-3.7
Chronotype (morning person)	3.0	6.9	11.8	-1.9	-0.2	2.0	-0.9	-2.9	-3.0	-2.9	-3.1	0.9	-3.2	-2.8	-3.2	-3.4	-2.5	-1.0	-2.3	-2.7	-3.2	-3.1	-3.4	-3.1	-2.8	-3.2	-2.8
Mother’s age at death	3.0	3.8	7.2	-1.4	1.0	-2.0	0.1	-2.2	-2.3	-2.3	-2.3	0.5	-2.4	-2.2	-2.1	-2.1	-1.9	-1.9	-1.1	-2.3	-2.2	-2.7	-2.2	-2.3	-1.6	-1.9	-2.3
HDL Cholesterol	2.9	4.9	8.0	2.7	1.6	0.6	1.9	2.5	2.4	2.4	2.5	2.4	2.4	2.3	2.5	2.2	2.8	1.9	1.1	2.4	2.4	1.8	2.5	2.4	2.5	2.6	2.0
Average weekly fortified wine intake	2.9	3.4	7.1	1.7	1.8	0.3	0.6	2.3	2.2	2.2	2.0	-0.1	2.2	2.2	2.1	1.9	2.1	1.7	0.8	2.1	1.5	1.8	1.9	2.0	2.7	2.1	2.3
Body mass index (BMI)	2.8	11.9	21.5	-3.7	-1.9	0.4	-0.3	-4.3	-4.2	-4.1	-4.0	-1.2	-4.2	-4.1	-4.1	-2.5	-4.3	-2.1	-2.0	-4.0	-3.8	-3.4	-3.8	-4.0	-4.6	-4.3	-3.6
Trunk fat mass	2.7	11.8	23.0	-4.5	-1.8	-1.1	0.0	-4.0	-4.0	-3.9	-3.9	-3.3	-4.0	-3.9	-4.0	-2.0	-4.0	-2.3	-2.2	-3.9	-3.4	-3.0	-3.8	-3.9	-4.8	-4.3	-3.4
Had other major operations	2.7	3.3	6.9	-1.5	0.1	-1.0	1.2	-2.0	-1.9	-2.0	-2.0	0.6	-2.0	-2.0	-2.1	-2.0	-2.2	-0.5	-1.7	-2.1	-1.8	-2.6	-2.1	-2.0	-2.2	-1.9	-2.1
Arm fat mass (right)	2.7	10.9	19.1	-4.1	-1.7	-0.3	-0.2	-4.0	-4.0	-3.9	-3.9	-2.4	-4.0	-3.9	-3.9	-1.9	-3.9	-2.1	-2.3	-3.9	-3.5	-3.0	-3.6	-3.9	-4.4	-4.2	-3.2
Whole body fat mass	2.7	11.4	21.3	-4.3	-1.9	-0.8	-0.2	-4.0	-3.9	-3.9	-3.9	-2.8	-4.0	-3.8	-3.9	-2.1	-4.0	-2.1	-2.2	-3.9	-3.4	-3.0	-3.8	-3.9	-4.6	-4.2	-3.4
Supplements: Vitamin C	2.7	3.2	7.8	2.2	0.8	-0.8	1.1	1.9	1.9	1.9	1.9	1.8	1.9	2.0	1.8	2.0	2.3	2.8	0.4	1.7	2.3	1.6	1.6	1.8	1.6	1.6	2.1
Commuting to job workplace: Public transport	2.7	3.2	5.6	1.6	1.2	-0.5	1.8	2.1	2.1	2.0	2.1	-0.0	2.0	2.0	2.1	0.8	2.3	1.3	1.0	2.1	2.3	1.8	2.0	2.1	2.4	2.3	1.9
Blood Red Count	2.5	24.4	38.4	-6.2	-4.0	1.7	-2.6	-5.5	-5.5	-5.5	-5.5	-4.4	-5.5	-5.3	-5.7	-4.5	-6.1	-2.9	-3.3	-5.4	-5.6	-4.6	-5.6	-5.6	-5.8	-5.9	-5.0
Arm fat mass (left)	2.5	10.3	18.2	-4.0	-1.8	-0.4	-0.2	-3.9	-3.8	-3.8	-3.7	-2.4	-3.8	-3.7	-3.7	-2.0	-3.9	-2.0	-2.2	-3.8	-3.4	-2.9	-3.5	-3.7	-4.3	-4.1	-3.1
Vascular/heart problems diagnosed by doctor	2.5	6.8	12.4	2.6	1.2	-0.4	0.1	3.0	3.0	3.0	2.9	0.9	3.0	3.0	2.8	3.0	3.0	2.9	0.1	2.9	2.8	3.1	2.6	2.9	3.3	2.6	3.5
Medication: Blood pressure	2.4	4.3	8.2	-2.2	-1.4	0.6	-0.9	-2.2	-2.2	-2.3	-2.3	-1.1	-2.4	-2.2	-2.3	-2.3	-2.5	-1.8	-0.9	-2.0	-2.3	-2.4	-2.4	-2.3	-2.5	-2.2	-2.9
Type 2 Diabetes (T2D) (2012)	2.3	2.6	4.8	1.5	0.3	1.0	-0.3	2.0	1.9	1.8	1.7	0.9	1.9	1.9	2.0	2.2	1.9	1.5	0.0	2.0	0.0	1.6	2.0	1.7	2.0	1.8	2.2
Hayfever, allergic rhinitis or eczema	2.3	5.0	9.2	2.4	1.9	-3.0	2.4	2.3	2.3	2.3	2.2	1.4	2.3	2.3	2.4	1.4	2.4	1.6	2.3	2.6	1.6	2.3	2.2	2.3	3.0	2.3	2.7
Medication: Bendroflumethiazide	2.3	3.5	6.1	-2.2	-1.5	0.6	-1.8	-2.1	-2.1	-2.2	-2.0	-1.8	-2.1	-2.3	-2.1	-0.7	-1.8	-2.4	-0.8	-2.1	-1.6	-1.7	-1.9	-1.9	-2.5	-1.9	-2.2
Alzheimer’s Disease (in mother)	2.2	2.5	5.3	1.5	1.3	0.4	1.4	1.8	1.6	1.7	1.7	-0.3	2.0	1.7	1.8	1.8	2.0	0.7	1.6	1.6	1.1	1.7	1.9	1.7	2.3	1.9	2.0
Alzheimer’s Disease (including proxy)	2.2	3.2	6.8	2.1	2.6	0.6	2.3	2.0	1.8	1.9	1.8	1.5	1.9	1.9	1.9	1.2	2.6	1.4	0.7	1.9	1.5	1.1	1.6	1.8	2.4	2.0	1.5
Qualifications: None of the above	2.2	4.7	8.1	-2.5	-2.1	1.3	-1.6	-2.4	-2.4	-2.4	-2.4	-0.9	-2.5	-2.3	-2.5	-2.0	-2.6	-1.6	-1.2	-2.4	-2.5	-1.9	-2.3	-2.4	-2.9	-2.6	-2.2
Ever had hysterectomy (womb removed)	2.1	2.4	4.8	-1.8	-1.5	0.0	-1.4	-1.8	-1.8	-1.8	-1.7	-2.2	-1.7	-1.9	-1.7	-0.9	-1.7	-0.9	-0.6	-1.7	-1.5	-1.4	-1.4	-1.8	-1.9	-1.8	-1.3
Diabetes (father)	2.1	2.6	17.5	2.0	3.1	1.0	4.2	1.4	1.2	1.3	1.0	2.6	1.3	1.5	1.2	0.2	1.2	2.3	0.6	1.2	0.8	-0.1	0.9	0.9	1.5	1.2	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.7	10.1	-1.5	-1.5	0.8	-0.8	-1.9	-1.8	-1.8	-1.8	-0.2	-1.8	-1.8	-1.8	-2.1	-2.0	-3.2	-0.7	-1.7	-1.5	-1.1	-1.7	-1.8	-1.9	-1.7	-1.3
Allergy	2.1	4.8	9.2	-2.6	-2.5	2.7	-2.4	-2.3	-2.2	-2.2	-2.2	-1.3	-2.1	-2.1	-2.4	-0.4	-2.1	-1.6	-2.4	-2.5	-1.6	-2.2	-2.3	-2.3	-3.0	-2.3	-2.6
Mouth/teeth dental problems: Dentures	2.1	3.6	7.7	-2.5	-1.8	0.5	-2.8	-2.0	-2.0	-2.0	-1.9	-2.2	-2.3	-1.9	-2.0	-1.6	-1.9	-1.2	-2.4	-1.9	-1.8	-0.8	-1.9	-1.9	-1.9	-2.4	-1.3
Commuting to job workplace: Car/motor vehicle	2.1	2.5	5.9	-1.7	-2.0	0.0	-1.5	-1.8	-1.7	-1.7	-1.6	-1.3	-1.5	-1.7	-1.7	-0.5	-2.3	-1.3	-0.0	-1.6	-1.6	-1.2	-1.5	-1.7	-2.4	-1.8	-1.8
Osteoarthritis (self-reported)	2.1	2.7	7.0	-0.7	0.4	0.7	-1.4	-1.8	-1.9	-1.8	-1.8	0.7	-1.7	-1.8	-1.7	-2.6	-2.4	-2.2	-0.3	-1.8	-2.1	-1.7	-1.4	-1.7	-1.8	-1.5	-2.0
Pack years adult smoking proportion	2.0	3.0	10.5	-1.6	0.1	0.4	-0.3	-2.2	-2.2	-2.1	-2.0	0.3	-2.2	-2.2	-2.2	-0.1	-1.1	0.0	-3.2	-2.3	-0.9	-1.9	-1.9	-2.0	-1.8	-2.3	-1.4
Lung cancer (father)	2.0	2.4	4.5	-2.1	-0.9	-1.3	-0.4	-1.7	-1.7	-1.7	-1.6	-1.8	-1.6	-1.8	-1.7	-1.2	-1.1	-1.2	-1.4	-1.7	-1.3	-1.6	-1.6	-1.6	-2.0	-1.7	-1.9
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	5.4	1.4	-0.1	-0.2	0.2	2.0	2.1	2.1	2.1	-0.4	2.3	2.1	2.2	2.1	1.6	1.7	1.3	1.9	2.2	2.3	2.3	2.1	1.8	2.0	2.3
Mouth/teeth dental problems: Loose teeth	2.0	2.4	4.7	1.9	-0.3	-1.1	-0.1	1.9	1.8	1.8	1.5	0.9	1.6	1.9	1.8	2.0	2.2	0.9	1.0	1.7	1.5	1.9	1.6	1.5	1.6	1.5	1.9
Basal cell carcinoma (self-reported)	2.0	2.4	4.0	1.8	1.7	-1.3	1.6	1.9	1.8	1.8	1.7	0.5	1.7	1.8	1.8	0.3	2.0	1.7	1.4	1.8	1.5	0.6	1.6	1.6	1.6	1.9	1.0
Pack years of smoking	2.0	2.9	11.1	-1.6	-0.1	0.6	-0.6	-2.2	-2.1	-2.0	-1.9	0.3	-2.2	-2.1	-2.2	-0.2	-1.1	0.2	-3.3	-2.2	-0.8	-1.7	-2.0	-1.9	-1.7	-2.3	-1.3
Blood Eosinophil Count	1.9	14.5	24.5	4.1	-0.9	-0.8	0.3	3.7	4.2	4.2	4.8	1.0	4.3	3.9	4.3	4.4	3.9	3.8	4.1	4.4	3.9	3.4	4.8	4.8	4.9	5.0	3.6
Other serious medical condition/disability diagnosed by doctor	1.9	2.4	6.1	1.5	2.5	-1.2	2.1	1.7	1.6	1.7	1.6	0.8	1.8	1.8	1.6	1.8	1.6	0.5	0.6	1.5	1.7	1.4	1.4	1.6	1.4	1.6	1.5
Qualifications: College or University degree	1.9	6.1	10.0	2.5	2.0	-0.6	2.8	2.6	2.7	2.6	2.9	0.3	2.7	2.4	2.8	3.2	3.1	2.2	2.0	2.7	2.9	2.4	2.9	2.8	2.4	2.8	2.5
Hypertension (Self-reported)	1.9	5.2	11.3	-2.2	-1.0	1.0	0.0	-2.7	-2.7	-2.7	-2.5	-0.6	-2.6	-2.8	-2.5	-2.5	-2.7	-2.2	0.2	-2.7	-2.2	-3.1	-2.1	-2.4	-3.0	-2.1	-3.4
Myopia	1.9	2.8	5.0	1.7	0.6	0.8	1.9	2.0	1.9	1.9	1.9	1.3	1.9	1.8	1.9	1.8	1.9	1.9	0.7	2.1	2.2	1.3	1.6	1.9	1.5	1.8	1.4
Supplements: Zinc	1.8	2.0	5.2	0.9	0.6	0.2	1.4	1.5	1.5	1.6	1.5	-0.4	1.6	1.6	1.5	1.6	1.6	1.1	0.3	1.4	1.8	2.0	1.5	1.6	1.7	1.3	2.3
Medication: Aspirin	1.8	2.4	4.7	-2.2	0.7	-0.9	0.4	-1.5	-1.6	-1.6	-1.7	-1.4	-1.8	-1.5	-1.5	-1.9	-1.6	-2.0	-0.4	-1.4	-2.0	-1.7	-1.7	-1.7	-1.8	-1.5	-2.0
Medication: Aspirin	1.8	2.4	5.1	-2.3	0.4	-0.7	0.4	-1.4	-1.6	-1.6	-1.8	-1.4	-1.8	-1.5	-1.6	-1.7	-1.5	-1.8	-0.6	-1.3	-2.0	-1.8	-1.9	-1.7	-1.8	-1.6	-2.0
Allergy or Eczema	1.7	4.4	8.4	2.0	2.7	-2.5	2.9	2.0	2.0	2.0	2.0	1.2	2.0	1.9	2.0	1.6	2.3	1.4	1.9	2.2	1.4	2.5	1.9	2.1	2.7	1.9	2.8
High blood pressure	1.7	4.8	9.8	-2.2	-0.9	0.5	0.4	-2.6	-2.5	-2.5	-2.4	-1.0	-2.5	-2.6	-2.3	-2.5	-2.7	-2.3	0.3	-2.5	-2.2	-2.7	-2.0	-2.3	-2.9	-2.0	-3.1
Alcohol usually taken with meals	1.7	2.8	6.7	2.1	2.6	-1.2	1.0	1.7	1.6	1.5	1.5	2.3	1.4	1.6	1.6	1.5	2.3	1.6	-0.2	1.7	1.7	0.8	1.4	1.4	2.5	1.7	1.9
Ever highly irritable/argumentative for 2 days	1.7	2.1	4.3	1.2	0.2	-0.3	0.7	1.5	1.5	1.6	1.7	-1.2	1.6	1.5	1.4	1.4	2.0	1.0	0.7	1.6	1.6	2.1	1.6	1.7	1.8	1.5	2.0
Headache pain in last month	1.7	2.9	5.7	-1.5	-0.2	-0.7	-0.1	-2.0	-2.0	-2.1	-2.1	-0.7	-2.2	-2.1	-1.9	-2.0	-1.5	-1.9	-0.5	-2.1	-2.4	-1.6	-1.8	-2.0	-1.6	-1.9	-1.5
Medication: Ibuprofen	1.7	2.0	4.7	1.2	1.1	1.2	0.7	1.4	1.5	1.5	1.8	0.2	1.7	1.4	1.5	0.8	2.2	1.0	1.0	1.2	1.3	1.3	1.6	1.8	2.0	1.9	1.5
Illnesses of father: Heart disease	1.7	2.4	5.3	-2.3	-0.3	-1.2	0.0	-1.6	-1.6	-1.7	-1.9	-2.0	-1.8	-1.5	-1.8	-1.5	-1.1	-1.4	-1.5	-1.3	-1.6	-1.3	-2.1	-1.9	-1.5	-2.0	-1.0
Unable to work because of sickness or disability	1.7	2.2	4.9	-0.5	1.6	-0.1	1.8	-1.5	-1.6	-1.6	-1.7	1.5	-1.8	-1.6	-1.7	-1.4	-0.8	-0.4	-1.4	-1.6	-0.9	-2.2	-1.9	-1.7	-1.6	-1.6	-1.8
Hair/balding pattern: Pattern 3	1.6	2.4	5.0	-1.1	-1.9	-1.0	-0.2	-1.8	-1.8	-1.7	-1.6	-0.1	-1.5	-1.8	-1.7	-2.2	-1.6	-1.6	-0.2	-1.9	-1.9	-1.7	-1.4	-1.6	-1.4	-1.4	-2.1
Had major operations	1.6	1.8	4.5	1.0	2.1	1.8	1.7	1.6	1.4	1.3	1.2	0.9	1.2	1.4	1.5	0.8	1.6	1.6	0.6	1.4	1.0	1.1	1.1	1.3	1.8	1.3	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.7	3.2	0.5	-0.1	-0.2	0.8	1.4	1.5	1.6	1.6	-1.6	1.5	1.6	1.4	-0.4	0.9	0.9	0.9	1.5	1.7	1.8	1.4	1.7	1.1	1.5	1.6
Verbal and Numeric Reasoning (VNR)	1.4	3.2	6.8	-1.5	-0.0	-0.2	-0.5	-2.0	-2.1	-2.2	-2.1	0.4	-2.0	-2.1	-2.0	-1.2	-1.9	-1.7	-1.0	-2.0	-2.2	-2.6	-2.0	-2.2	-2.1	-1.8	-2.6
Triglycerides	1.4	2.2	5.0	-1.2	0.6	0.2	0.4	-1.6	-1.6	-1.7	-1.6	-0.1	-1.7	-1.7	-1.7	-2.2	-2.0	-1.9	-0.2	-1.6	-2.0	-1.7	-1.9	-1.6	-1.3	-1.4	-1.4
BMI	1.4	8.2	14.1	-3.0	-1.6	-0.4	-0.5	-3.4	-3.3	-3.2	-3.4	-0.5	-3.4	-3.1	-3.3	-2.4	-3.8	-2.2	-1.4	-3.2	-3.6	-2.9	-3.4	-3.4	-3.6	-3.5	-3.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	5.5	-2.4	-1.4	0.5	-0.1	-2.1	-2.0	-2.1	-1.9	-1.5	-2.2	-2.2	-2.2	-1.8	-1.7	-1.5	-0.7	-2.1	-1.7	-1.3	-2.0	-1.9	-2.3	-2.1	-1.2
Waist circumference	1.4	5.2	11.0	-2.7	-1.6	-0.3	0.3	-2.8	-2.7	-2.6	-2.6	-1.9	-2.6	-2.6	-2.6	-1.5	-3.1	-1.8	-0.6	-2.6	-2.5	-2.0	-2.3	-2.6	-3.3	-2.7	-2.3
Mouth/teeth dental problems	1.4	2.2	9.1	1.9	2.5	-1.3	3.0	1.3	1.2	1.2	1.3	2.3	1.3	1.1	1.4	0.6	1.0	1.0	1.4	1.3	1.3	-0.2	1.3	1.3	1.4	1.9	0.2
Number of full sisters	1.4	1.7	3.7	-1.6	-0.8	0.6	-0.5	-1.5	-1.5	-1.5	-1.5	-0.3	-1.4	-1.4	-1.5	-1.1	-1.9	-0.3	-1.4	-1.5	-1.4	-1.4	-1.5	-1.5	-1.5	-1.6	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	3.4	-1.2	-1.8	0.2	-0.8	-1.5	-1.5	-1.5	-1.7	-0.2	-1.6	-1.4	-1.4	-0.9	-1.7	-1.4	-1.0	-1.5	-1.3	-0.8	-1.4	-1.7	-1.2	-1.8	-1.0
Hearing aid user	1.4	1.5	3.8	-0.9	-0.8	-1.3	-2.0	-1.2	-1.2	-1.2	-1.3	0.3	-1.1	-1.1	-1.4	-1.0	-1.5	-1.0	-1.3	-1.3	-0.8	-1.2	-1.4	-1.3	-1.9	-1.4	-1.4
Supplements: Calcium	1.4	1.5	3.8	1.8	0.3	-2.0	1.6	1.3	1.3	1.3	1.4	1.2	1.4	1.3	1.2	0.5	1.1	0.5	1.4	1.1	1.4	0.8	1.3	1.4	0.8	1.6	0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	5.1	-2.1	-0.4	-0.3	0.2	-2.1	-2.1	-2.1	-2.0	-0.3	-2.3	-2.1	-2.2	-1.1	-1.6	-0.2	-1.6	-2.1	-1.5	-1.9	-2.1	-2.0	-2.2	-2.2	-1.3
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	6.2	1.2	0.9	0.0	-0.4	1.2	1.1	1.2	1.3	0.2	1.4	1.2	1.4	-0.2	1.5	-0.4	1.0	1.5	0.8	2.1	1.6	1.3	2.5	1.5	2.4
Medication: Cholesterol lowering	1.3	2.1	6.2	-0.3	1.0	-0.2	-0.5	-1.4	-1.5	-1.5	-1.5	1.8	-1.7	-1.4	-1.6	-2.5	-0.5	-1.1	-1.6	-1.3	-1.7	-2.2	-2.0	-1.5	-0.6	-1.2	-1.9
Exposure to tobacco smoke at home	1.3	1.5	2.5	1.3	-0.8	1.6	-0.5	1.4	1.5	1.5	1.4	0.2	1.5	1.5	1.3	1.1	1.1	0.8	1.1	1.6	1.1	1.1	1.2	1.4	1.1	1.4	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	3.3	1.1	-0.4	-1.6	1.0	1.2	1.3	1.3	1.5	-0.2	1.5	1.2	1.4	-0.2	0.9	0.4	1.8	1.4	1.4	1.1	1.7	1.5	1.4	1.7	1.1
Ever depressed for a whole week	1.3	1.6	2.7	1.6	1.0	-0.8	1.1	1.4	1.4	1.3	1.3	1.2	1.4	1.4	1.3	0.7	1.6	0.7	-0.3	1.4	1.6	1.3	1.3	1.2	1.6	1.3	1.6
Rheumatoid Arthritis	1.2	1.6	3.6	1.3	-0.2	-1.7	0.7	1.5	1.4	1.4	1.1	0.6	1.4	1.5	1.4	0.6	1.5	1.3	1.2	1.4	1.3	1.6	1.2	1.2	1.5	1.1	1.9
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	5.1	0.8	-0.4	-0.3	-0.6	1.1	1.1	1.1	1.2	-0.4	1.3	1.1	1.1	1.6	1.1	0.1	-0.1	1.2	1.5	2.3	1.3	1.2	1.3	0.8	1.9
Pulse wave reflection index	1.2	1.5	3.6	1.1	0.6	-1.1	0.9	1.3	1.4	1.4	1.2	0.6	1.3	1.5	1.3	1.1	1.9	1.5	0.7	1.3	1.1	1.4	1.2	1.3	1.2	1.1	1.7
Alcohol intake frequency.	1.2	2.7	5.3	-2.0	-2.2	0.6	-1.8	-1.8	-1.8	-1.7	-1.9	-1.4	-1.9	-1.6	-1.8	-0.8	-1.7	-1.8	-0.6	-1.7	-1.6	-1.1	-1.8	-1.8	-2.3	-2.0	-1.6
Qualifications: nursing, teaching	1.2	1.8	5.4	2.2	1.8	-0.9	1.6	1.1	1.1	1.0	1.1	2.3	0.9	1.0	1.2	1.2	1.5	1.3	0.4	1.1	1.0	1.2	1.3	1.1	1.9	1.1	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.7	1.2	-0.5	-1.6	-0.1	1.3	1.3	1.4	1.4	-0.3	1.2	1.3	1.4	1.4	0.7	0.1	1.6	1.3	1.5	1.5	1.5	1.4	0.8	1.4	0.9
Guilty feelings	1.2	1.8	3.5	1.0	0.5	-0.5	0.3	1.6	1.6	1.5	1.6	-0.5	1.5	1.5	1.6	1.7	1.4	0.4	1.1	1.8	1.5	1.9	1.6	1.5	1.4	1.6	1.7
Eye problems/disorders: Glaucoma	1.2	1.5	4.3	-1.3	-0.3	0.4	-0.7	-1.2	-1.3	-1.2	-1.2	-1.4	-1.1	-1.1	-1.1	-2.1	-1.7	-1.1	0.6	-1.2	-1.6	-1.2	-0.9	-1.2	-1.3	-1.1	-1.8
Mean Putamen Volume	1.1	1.3	3.1	1.2	1.4	1.3	0.7	1.1	1.0	1.1	1.0	1.5	1.0	1.1	1.1	0.6	1.2	0.9	-0.6	1.0	1.5	1.2	1.1	0.9	1.5	1.0	1.8
Illnesses of mother	1.1	1.3	3.1	0.9	0.0	-0.5	-0.2	1.4	1.4	1.4	1.2	-0.5	1.4	1.5	1.3	1.0	0.9	1.4	1.0	1.5	0.6	1.5	1.2	1.2	1.8	1.1	1.5
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	8.3	1.5	2.9	-0.4	2.9	0.9	0.9	0.9	1.1	1.6	1.1	0.8	1.0	1.5	1.6	1.2	0.0	0.9	1.5	0.1	1.1	1.1	1.1	1.4	0.7
Exposure to tobacco smoke outside home	1.1	1.5	5.4	-0.2	-0.8	2.3	-0.6	-1.2	-1.2	-1.3	-1.3	1.4	-1.3	-1.2	-1.2	-1.2	-1.6	-0.0	-1.0	-1.2	-1.0	-1.5	-1.2	-1.4	-1.2	-1.4	-1.3
Family relationship satisfaction	1.1	1.4	3.9	0.2	-0.5	-0.3	0.8	1.3	1.4	1.4	1.2	-1.6	1.1	1.5	1.2	2.0	0.7	1.9	-0.0	1.5	1.4	1.6	1.0	1.2	0.7	0.7	1.4
Alzheimer’s Disease (in father)	1.0	1.1	5.7	1.4	2.4	0.2	1.7	0.9	0.8	0.8	0.9	2.1	0.6	0.7	0.7	-0.4	1.5	1.3	-0.4	1.0	0.9	-0.3	0.5	0.8	0.9	1.0	-0.1
Bipolar Disorder (2011)	1.0	1.0	3.3	1.6	-0.5	1.6	-0.2	0.8	0.9	0.8	1.0	1.8	0.9	0.7	0.9	0.5	1.1	1.1	0.0	1.1	0.0	0.7	1.0	0.9	1.2	0.9	1.3
Fasting Glucose	1.0	1.2	2.7	-0.3	1.1	-0.9	1.5	-1.3	-1.3	-1.0	-1.3	0.8	-1.1	-0.8	-1.2	-1.6	-1.0	-0.8	-0.8	-1.2	-0.9	-1.4	-1.1	-1.2	-1.2	-1.1	-1.3
Sensitivity / hurt feelings	1.0	1.7	3.5	-0.5	-0.6	0.7	-0.4	-1.4	-1.5	-1.5	-1.5	1.4	-1.5	-1.4	-1.4	-0.7	-1.9	-1.5	-0.8	-1.3	-1.2	-1.4	-1.6	-1.6	-1.6	-1.5	-1.3
Serious illness, injury or assault to yourself	1.0	1.2	5.7	-1.0	0.9	0.6	2.4	-0.9	-1.0	-1.1	-1.3	0.3	-1.2	-0.9	-1.1	0.1	-1.0	-0.2	-1.6	-1.1	-0.9	-0.9	-1.4	-1.3	-1.1	-1.5	-0.5
Weight	1.0	5.0	10.4	-3.2	-1.6	-0.5	0.1	-2.7	-2.6	-2.5	-2.4	-3.1	-2.5	-2.5	-2.5	-0.7	-2.7	-1.5	-0.8	-2.6	-2.2	-1.5	-2.1	-2.4	-3.2	-2.8	-1.8
Hip circumference	1.0	4.5	9.5	-2.6	-1.4	-0.5	0.1	-2.5	-2.5	-2.4	-2.4	-1.7	-2.4	-2.4	-2.4	-1.3	-2.8	-1.9	-0.5	-2.5	-2.4	-1.8	-2.2	-2.5	-3.1	-2.5	-2.0
Pulse rate	1.0	1.7	3.0	-1.5	-0.8	1.7	-1.0	-1.4	-1.4	-1.4	-1.3	-1.7	-1.4	-1.5	-1.5	-0.8	-1.3	-0.2	-1.0	-1.5	-1.2	-1.2	-1.4	-1.3	-1.3	-1.6	-1.3
Glaucoma (self-reported)	1.0	1.2	3.3	-1.2	-0.5	1.1	-0.5	-1.0	-1.0	-1.0	-0.9	-1.8	-0.8	-1.0	-0.8	-1.7	-1.7	-0.7	1.0	-1.0	-1.1	-1.0	-0.6	-0.9	-1.5	-0.8	-1.8
Medication: Amlodipine	1.0	1.4	3.1	-0.3	0.9	1.7	0.3	-1.4	-1.5	-1.4	-1.3	0.9	-1.5	-1.5	-1.2	-0.8	-1.2	-0.8	0.1	-1.4	-1.4	-1.6	-1.0	-1.3	-1.1	-1.2	-1.5
Medication: Seretide 50 evohaler	1.0	1.1	5.0	1.2	1.2	-0.1	2.2	1.0	0.9	0.9	1.0	0.3	1.0	0.8	1.0	-0.7	1.0	0.3	1.1	1.0	1.4	1.1	1.1	1.1	1.1	1.0	1.2
Mood swings	1.0	1.8	4.6	-1.5	-2.1	-0.1	-0.5	-1.5	-1.4	-1.4	-1.3	-1.0	-1.5	-1.4	-1.4	-1.4	-2.1	-1.9	-0.2	-1.2	-1.3	-0.8	-1.1	-1.3	-1.8	-1.3	-1.4
Risk taking	1.0	1.5	6.3	0.3	1.2	1.4	0.4	1.1	1.1	1.1	0.9	-0.8	1.1	1.1	1.0	2.0	1.6	0.6	-0.9	1.2	1.4	1.9	0.9	0.9	1.5	0.6	2.5
Depression (Nagel 2018)	0.9	1.3	7.5	-1.5	-1.8	0.2	-1.5	-1.2	-1.1	-1.1	-1.1	-1.3	-1.0	-1.1	-1.1	-0.6	-1.1	-2.7	-0.7	-0.8	-0.8	0.2	-0.8	-1.0	-1.2	-1.1	-0.2
Body Mass Index (BMI) (2010)	0.9	1.2	5.4	-1.2	-2.3	-1.2	-2.0	-1.0	-0.8	-0.9	-0.9	-1.2	-0.9	-0.9	-1.1	0.2	-1.0	-1.5	-1.2	-0.7	-0.3	0.0	-1.3	-0.8	-1.6	-1.2	-0.3
Relative age of first facial hair	0.9	1.9	3.6	1.1	0.7	-1.8	0.3	1.5	1.5	1.4	1.5	-0.3	1.5	1.3	1.5	1.1	1.8	0.1	0.7	1.6	1.3	1.8	1.5	1.6	1.9	1.6	1.8
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.0	-0.6	0.0	-0.1	0.4	-1.2	-1.2	-1.2	-1.0	0.1	-1.1	-1.3	-1.0	-1.3	-2.0	-0.8	1.1	-1.1	-1.7	-1.2	-0.8	-1.1	-1.3	-1.0	-1.5
Current tobacco smoking	0.9	1.4	3.7	-1.3	-0.0	0.5	-0.0	-1.3	-1.3	-1.3	-1.3	-0.6	-1.2	-1.4	-1.2	-1.8	-1.9	-1.3	-0.8	-1.3	-0.9	-1.2	-1.0	-1.3	-1.3	-1.1	-1.4
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	4.7	-1.3	-1.6	-0.1	-0.4	-0.9	-0.8	-0.9	-0.8	-2.2	-0.7	-0.9	-0.9	-1.0	-1.2	-0.7	1.1	-1.0	-1.6	-0.8	-0.9	-0.8	-0.9	-0.7	-0.8
Medication: Ramipril	0.9	1.1	3.0	-0.8	0.4	1.4	0.1	-1.1	-1.2	-1.2	-1.3	0.9	-1.5	-1.1	-1.3	-1.1	-0.2	-0.2	-1.7	-1.1	-1.0	-1.1	-1.4	-1.3	-0.8	-1.4	-0.5
Qualifications: A levels/AS levels or equivalent	0.9	2.0	8.4	1.6	2.9	-0.1	2.3	1.2	1.0	1.0	1.1	1.4	1.1	1.0	1.2	2.2	2.0	0.8	-0.1	1.2	1.4	0.9	1.3	1.0	1.6	1.3	1.4
Breastfed as a baby	0.9	1.1	3.1	1.5	0.4	-0.2	1.2	0.9	1.0	1.0	1.2	1.3	1.0	0.8	1.1	0.9	1.6	0.4	0.6	0.7	1.8	0.8	1.2	1.3	1.0	1.3	0.8
Age at first live birth	0.9	1.7	3.7	1.5	1.7	0.3	1.8	1.5	1.4	1.4	1.3	0.2	1.4	1.4	1.4	1.3	1.9	0.2	1.7	1.2	0.9	0.9	1.1	1.3	1.4	1.6	0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.7	0.7	0.5	-0.6	0.2	1.3	1.2	1.2	0.9	-0.6	1.2	1.3	1.2	-1.2	1.0	-0.1	1.5	1.3	0.3	1.2	1.1	1.0	1.6	1.3	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	5.6	0.3	-0.2	0.4	0.1	1.3	1.3	1.3	1.4	-2.3	1.4	1.2	1.2	2.1	1.7	0.5	0.9	1.2	1.1	2.4	1.4	1.4	1.7	1.1	2.1
Smoking status: Current	0.9	1.4	3.4	-1.4	-0.4	0.4	-0.4	-1.3	-1.3	-1.3	-1.2	-0.9	-1.2	-1.4	-1.2	-1.7	-1.8	-1.3	-0.8	-1.3	-0.8	-1.1	-0.9	-1.2	-1.2	-1.1	-1.3
Average weekly champagne plus white wine intake	0.9	1.3	3.4	0.7	1.2	-0.4	1.3	1.3	1.3	1.2	1.2	0.0	1.2	1.2	1.2	1.8	1.4	0.2	0.1	1.2	1.7	1.0	1.1	1.2	1.1	1.4	1.1
Average weekly beer plus cider intake	0.9	1.3	4.2	-0.8	-0.3	0.1	-0.1	-1.4	-1.4	-1.3	-1.4	0.5	-1.2	-1.2	-1.3	-0.8	-1.3	-0.1	-1.0	-1.1	-1.5	-2.0	-1.2	-1.4	-1.0	-1.1	-1.7
Reaction Time	0.8	1.4	4.8	-1.3	-0.3	-1.3	0.7	-0.9	-0.9	-0.9	-1.0	-1.3	-1.0	-0.9	-0.9	-2.2	-2.1	-1.2	0.9	-0.7	-1.3	-1.1	-1.0	-1.0	-1.8	-1.0	-1.7
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.1	1.4	2.3	1.0	2.1	1.3	1.1	1.0	0.9	1.2	0.9	1.1	1.2	0.1	1.8	0.6	-0.2	1.0	1.0	1.2	0.9	0.9	1.7	1.0	1.9
Number of treatments/medications taken	0.8	1.4	3.3	-1.3	0.5	0.6	-0.0	-1.1	-1.2	-1.2	-1.2	-1.0	-1.4	-1.2	-1.2	-1.7	-1.5	-1.4	0.1	-1.1	-1.8	-1.1	-1.4	-1.1	-1.2	-1.1	-1.5
Average weekly spirits intake	0.8	0.9	1.9	1.4	0.7	-0.9	1.3	0.9	1.0	1.1	1.3	1.0	1.1	0.9	0.9	0.3	1.0	0.9	0.6	0.7	1.2	0.6	1.1	1.3	0.5	1.3	0.5
Hearing difficulty/problems: Yes	0.8	1.2	4.9	-0.9	-1.3	0.8	-1.8	-1.1	-1.1	-1.1	-1.1	-0.2	-1.0	-1.1	-1.0	0.5	-1.2	-2.2	-1.5	-1.1	-1.2	0.2	-0.9	-1.1	-0.6	-1.2	0.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	4.7	0.8	0.2	0.7	0.2	0.9	0.8	0.8	0.6	0.2	0.7	0.9	0.9	-1.0	0.5	-2.2	0.1	1.0	1.4	1.6	0.8	0.7	1.0	0.9	1.4
Medication: Co-codamol	0.8	0.9	1.9	-1.1	-0.5	-0.4	-1.1	-1.2	-1.2	-1.1	-1.0	-1.4	-1.0	-1.3	-1.1	-0.3	-0.7	-1.2	-1.2	-1.2	-0.8	-0.1	-0.7	-0.9	-0.7	-1.2	-0.3
Relative age voice broke	0.8	1.3	3.5	-1.1	-0.3	0.4	-0.5	-1.4	-1.3	-1.3	-1.2	-0.5	-1.2	-1.4	-1.4	-1.6	-0.9	-0.9	-1.9	-1.2	-0.9	-1.2	-1.3	-1.2	-0.8	-1.2	-1.2
Qualifications: CSEs or equivalent	0.8	1.1	2.2	0.8	-1.4	-0.3	-1.2	1.2	1.2	1.2	1.1	-0.1	1.3	1.3	1.2	-0.2	0.3	0.4	1.5	1.5	0.8	1.3	1.1	1.2	1.1	1.1	0.7
Father’s age at death	0.8	1.0	3.0	1.2	-1.2	-0.4	-0.4	1.1	1.2	1.3	1.1	-0.1	1.3	1.4	1.2	0.1	0.1	0.7	1.7	1.2	0.8	1.0	1.0	1.1	0.9	1.2	0.7
Number of live births	0.8	1.1	7.3	-1.6	-2.3	1.1	-1.8	-0.8	-0.6	-0.5	-0.3	-2.7	-0.5	-0.6	-0.6	0.4	-0.9	-0.8	0.1	-0.4	-0.8	0.1	-0.4	-0.2	-1.1	-0.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.5	1.0	1.0	0.4	0.9	1.0	1.0	1.0	1.2	0.6	1.2	0.9	1.0	0.8	1.6	0.8	0.4	0.8	0.8	0.9	1.1	1.2	1.6	1.3	1.2
Emphysema/chronic bronchitis	0.8	1.0	2.7	1.5	1.2	-0.7	1.3	1.0	1.0	1.0	1.0	1.6	0.9	0.9	1.1	-0.3	1.1	0.9	0.6	1.1	0.9	0.3	1.0	0.9	0.9	1.2	0.5
Migraine (self-reported)	0.8	1.0	3.8	0.6	-0.2	1.1	-0.9	0.7	0.8	0.9	1.0	-1.4	0.9	0.8	1.0	0.9	0.7	-0.9	1.6	0.6	0.7	1.9	1.2	1.1	0.9	0.9	1.3
Medication: Allopurinol	0.8	1.1	3.1	1.2	0.5	-0.2	1.0	1.1	1.1	1.2	1.2	0.7	1.2	1.2	1.1	1.3	1.1	1.8	0.2	1.2	1.3	0.7	1.1	1.1	0.9	1.0	0.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	16.3	-0.6	-3.0	1.0	-4.0	-0.2	-0.2	-0.1	-0.2	-1.6	-0.2	-0.1	-0.2	1.0	-0.0	-0.4	-0.7	-0.1	-0.3	1.0	-0.1	-0.2	-0.2	-0.6	0.7
Ever taken oral contraceptive pill	0.8	0.9	4.6	0.8	1.1	-0.6	1.7	0.7	0.7	0.8	1.0	-0.2	1.0	0.7	0.8	1.7	0.6	2.1	1.2	0.6	0.6	0.3	1.1	0.9	0.6	0.9	0.2
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.0	-1.1	-0.1	0.0	-0.7	-1.0	-1.1	-1.1	-1.2	-0.5	-1.3	-1.0	-1.2	-1.7	-0.8	-0.5	-1.0	-0.8	-1.5	-1.1	-1.4	-1.2	-0.8	-1.2	-0.9
Medication: Levothyroxine sodium	0.7	1.2	2.5	0.9	-0.6	1.0	-0.4	1.4	1.4	1.5	1.4	0.7	1.6	1.5	1.4	-0.8	0.2	1.1	1.5	1.3	0.7	0.8	1.2	1.4	0.8	1.5	0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.5	0.9	-0.5	0.8	0.4	1.0	1.0	1.0	0.9	0.4	0.9	1.1	0.8	0.8	1.0	1.4	-0.6	1.1	1.4	1.1	0.6	0.9	1.1	0.7	1.6
Tense / ‘highly strung’	0.7	1.1	2.7	-1.3	-1.0	0.2	-1.6	-1.1	-1.1	-1.1	-1.1	-0.4	-1.2	-1.0	-1.2	-0.6	-1.0	-0.6	-1.6	-1.1	-1.5	-0.8	-1.2	-1.2	-0.8	-1.3	-0.7
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	3.3	0.5	0.1	1.0	0.9	1.3	1.4	1.4	1.4	-0.6	1.6	1.4	1.4	-0.4	0.3	1.0	1.8	1.2	0.9	0.9	1.4	1.4	0.8	1.6	0.6
Mean time to correctly identify matches	0.7	1.4	3.6	-1.5	-0.8	-1.0	0.2	-1.0	-1.0	-1.0	-1.1	-1.5	-1.1	-0.9	-1.0	-1.6	-1.8	-1.5	0.4	-0.8	-1.3	-1.1	-1.1	-1.1	-1.9	-1.1	-1.7
Overall health rating	0.7	1.4	3.9	-1.3	-0.8	-0.3	0.2	-1.2	-1.2	-1.1	-1.1	-0.8	-1.5	-1.2	-1.2	-2.0	-1.8	-1.1	0.3	-1.3	-1.5	-1.0	-1.2	-1.0	-1.6	-1.1	-1.6
Loneliness, isolation	0.7	0.9	6.1	-0.2	-2.5	-1.6	-1.4	-0.6	-0.4	-0.4	-0.4	0.3	-0.7	-0.4	-0.7	-1.4	-1.1	-0.9	0.8	-0.5	-0.8	-0.5	-0.8	-0.4	-1.2	-0.5	-1.3
Schizophrenia (2014)	0.6	1.3	5.2	1.8	2.3	0.7	0.9	1.3	1.1	1.2	1.2	1.7	1.1	1.2	1.4	0.9	1.4	0.0	0.0	1.1	0.0	0.0	1.4	1.2	0.0	0.0	1.1
Heel T-Score	0.6	4.6	13.1	-1.8	-1.3	-0.7	-0.7	-2.4	-2.4	-2.5	-2.3	0.1	-2.4	-2.6	-2.4	-3.6	-2.9	-2.7	-0.9	-2.5	-1.9	-1.8	-2.1	-2.2	-2.6	-2.3	-2.1
Cardiovascular Disease	0.6	1.9	4.1	-0.9	-0.1	1.4	0.2	-1.7	-1.7	-1.6	-1.4	0.8	-1.6	-1.9	-1.4	-1.9	-1.2	-2.0	0.6	-1.8	-1.1	-1.9	-1.0	-1.2	-1.3	-0.9	-2.0
Past tobacco smoking	0.6	1.2	2.4	1.3	1.5	0.0	1.2	1.1	1.1	1.1	1.1	1.6	1.2	1.1	1.0	0.9	1.5	1.5	0.8	1.1	1.0	0.2	0.8	1.1	0.7	1.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.1	-1.8	-1.3	0.1	0.4	-0.8	-0.8	-0.8	-0.9	-1.7	-0.9	-0.7	-0.9	-0.9	-1.4	-1.2	-0.1	-0.6	-1.0	-0.4	-1.0	-0.9	-1.0	-1.0	-0.3
Asthma	0.6	1.3	4.5	1.2	2.1	-0.8	1.8	0.8	0.8	0.7	1.0	0.6	0.7	0.5	1.0	-1.2	1.3	0.8	1.3	1.1	0.8	0.7	1.1	1.1	1.9	1.2	1.1
Blood clot in the leg (DVT)	0.6	0.7	2.0	-1.0	-0.8	-0.1	-1.2	-0.7	-0.8	-0.7	-1.0	-1.2	-0.8	-0.5	-0.8	-0.9	-1.2	-1.4	-0.4	-0.7	-0.6	-0.0	-0.9	-1.0	-1.2	-1.1	-0.3
Number of full brothers	0.6	0.7	2.9	-0.6	0.0	-0.4	0.4	-0.9	-0.9	-0.8	-0.9	0.6	-0.9	-0.8	-0.8	-1.7	-1.2	-1.0	0.2	-0.6	-1.0	-1.3	-0.8	-0.9	-0.9	-0.6	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.7	0.5	-0.3	-0.5	0.9	1.1	1.1	1.1	1.0	-0.5	0.9	1.1	1.0	0.6	1.2	0.0	0.4	1.2	1.2	1.3	0.9	1.0	0.8	1.0	1.1
Smoking status: Previous	0.6	0.9	3.3	-1.1	-1.8	-0.3	-1.4	-0.8	-0.8	-0.8	-0.9	-1.5	-1.0	-0.8	-0.8	-0.7	-1.6	-1.4	0.1	-0.8	-1.2	-0.0	-0.7	-0.9	-0.6	-0.9	-0.3
Asthma (self-reported)	0.6	1.2	3.6	1.0	1.8	-0.9	1.7	0.8	0.8	0.7	1.0	0.3	0.7	0.5	1.0	-1.2	1.1	0.8	1.5	1.1	0.7	0.7	1.1	1.1	1.9	1.2	1.1
Alcohol drinker status: Never	0.6	0.7	4.4	-1.2	-0.7	0.6	-1.7	-0.5	-0.5	-0.4	-0.6	-1.6	-0.6	-0.4	-0.5	-0.8	-0.5	-2.1	0.3	-0.4	-0.9	0.3	-0.5	-0.5	-0.7	-0.5	-0.2
Ulcerative Colitis	0.5	0.8	8.0	-0.0	0.8	2.8	-0.1	0.9	0.8	0.7	0.4	-1.4	0.4	0.7	0.6	0.8	1.3	0.9	-0.2	0.6	0.8	0.5	0.2	0.5	0.4	0.4	0.7
Vitamin and mineral supplements	0.5	0.6	2.5	-0.6	-1.1	0.9	-1.6	-0.8	-0.8	-0.8	-0.7	-0.1	-0.7	-0.9	-0.6	-0.7	-1.0	-0.8	0.3	-0.7	-1.2	-0.4	-0.3	-0.7	-0.8	-0.6	-0.9
Maternal smoking around birth	0.5	0.7	2.6	0.6	-1.2	-1.1	1.3	0.7	0.8	0.7	0.9	-0.7	0.8	0.6	0.8	0.3	0.8	0.5	0.9	0.9	1.6	0.6	1.0	1.0	-0.0	0.9	0.2
Stomach or abdominal pain in last month	0.5	0.6	2.0	0.4	-1.4	0.2	-0.1	0.8	0.9	0.9	0.8	-1.0	1.0	1.0	0.7	-0.7	0.5	-0.2	1.2	0.7	-0.0	0.6	0.6	0.8	0.7	0.9	0.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	4.3	-0.3	-2.1	0.3	-1.3	-0.6	-0.4	-0.4	-0.2	0.0	-0.4	-0.6	-0.4	-1.5	-1.6	-0.7	0.7	-0.4	-0.5	-0.1	-0.2	-0.2	-0.8	-0.3	-0.7
Hair/balding pattern: Pattern 2	0.5	0.7	4.2	0.6	2.0	0.7	0.4	0.6	0.6	0.7	0.7	0.0	0.7	0.5	0.8	1.0	0.8	-0.6	1.0	0.4	0.7	0.8	0.9	0.8	0.9	1.0	0.8
Had menopause	0.5	0.6	2.3	0.5	-0.1	-1.4	-0.3	-0.7	-0.8	-0.8	-0.6	1.5	-0.8	-0.9	-0.5	0.5	-1.0	-0.2	1.0	-0.8	-0.9	-0.9	-0.2	-0.7	-0.8	-0.5	-0.9
Diabetes (self-reported)	0.5	0.8	4.7	0.4	2.1	0.9	2.2	0.9	0.7	0.6	0.4	0.6	0.4	0.7	0.6	-0.3	0.8	0.2	-0.6	0.6	0.6	0.8	0.1	0.3	0.9	0.4	1.7
Standing height	0.5	4.7	23.8	-0.4	-0.1	-1.9	0.0	2.0	2.1	2.0	2.1	-4.9	2.4	2.0	2.1	3.1	2.1	0.3	1.7	1.9	2.0	3.2	2.2	2.1	1.8	1.9	2.8
Length of working week for main job	0.5	0.5	6.4	-0.9	-1.0	-2.5	0.2	-0.3	-0.3	-0.3	-0.2	-1.3	-0.1	-0.3	-0.2	0.9	-0.2	-0.6	0.6	-0.0	-0.5	-0.0	-0.1	-0.3	-0.5	-0.2	-0.3
Birth weight of first child	0.5	0.9	2.5	0.5	-0.8	-1.3	-1.0	0.6	0.8	0.8	1.1	-0.6	0.9	0.7	0.8	1.6	1.4	0.9	0.3	0.5	1.0	1.1	1.2	1.1	1.2	0.9	0.9
Worry too long after embarrassment	0.5	0.8	1.4	1.2	1.1	-1.1	0.9	0.9	0.8	0.8	0.9	0.6	0.9	0.7	1.0	0.9	0.9	0.1	1.2	0.9	1.2	0.8	1.1	0.8	0.6	1.0	0.7
Knee pain experienced in last month	0.5	0.7	4.3	0.8	-1.6	0.2	-0.7	0.9	0.9	0.9	0.8	-0.6	0.9	1.0	1.0	-0.1	-0.3	0.1	2.1	1.0	0.4	0.9	1.0	0.7	-0.1	0.8	0.1
Illnesses of siblings: Diabetes	0.5	0.7	1.7	1.2	1.1	1.0	1.2	0.8	0.7	0.7	0.6	0.8	0.7	0.8	0.8	0.6	1.3	0.5	0.7	0.7	0.5	0.2	0.7	0.6	1.1	0.9	0.6
Diabetes diagnosed by doctor	0.5	0.8	5.7	0.5	2.3	0.4	2.4	0.8	0.6	0.5	0.2	0.9	0.2	0.7	0.5	-0.5	0.7	0.2	-0.8	0.6	0.7	0.6	-0.0	0.1	0.6	0.2	1.2
Mineral and other dietary supplements	0.5	0.6	5.6	-0.5	-1.2	2.4	-0.8	-0.6	-0.5	-0.6	-0.3	-0.8	-0.4	-0.7	-0.5	1.1	-0.3	0.0	-0.1	-0.6	-0.4	-0.7	-0.2	-0.5	-0.8	-0.4	-1.1
Medication: Gliclazide	0.5	0.6	4.5	-0.5	2.1	0.5	1.7	-0.1	-0.3	-0.4	-0.4	0.3	-0.4	-0.3	-0.3	-1.0	0.3	0.4	-1.9	-0.4	0.1	-0.4	-0.6	-0.4	0.1	-0.5	0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.4	0.5	-0.2	0.2	0.7	0.8	0.9	1.0	0.9	-0.9	0.9	1.0	0.9	0.9	0.5	0.8	1.2	0.8	0.4	0.6	0.9	0.9	0.7	1.0	0.4
Cholesterol lowering medication	0.5	0.7	3.4	1.0	1.2	1.8	0.6	0.4	0.4	0.4	0.6	1.7	0.7	0.3	0.6	-0.6	0.6	-0.1	1.6	0.3	0.6	-0.3	0.8	0.6	0.2	1.1	-0.1
Pain experienced in last month	0.5	0.9	3.3	0.6	0.6	-1.7	0.2	0.8	0.8	0.8	0.8	1.0	0.9	0.8	0.7	1.8	1.2	1.7	-0.5	0.8	1.0	0.6	0.6	0.8	1.0	0.6	1.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	2.1	-0.9	-0.8	-0.3	-1.4	-0.6	-0.7	-0.6	-0.9	-1.2	-0.7	-0.4	-0.7	-1.1	-1.1	-1.5	-0.2	-0.6	-0.7	0.0	-0.8	-0.9	-1.0	-0.9	-0.3
Bipolar Disorder (2018)	0.4	0.6	6.1	1.2	0.5	0.9	-0.1	0.5	0.4	0.5	0.4	2.5	0.3	0.5	0.5	0.6	0.8	1.2	0.0	0.6	0.0	0.1	0.3	0.4	0.5	0.3	0.6
Bipolar Disorder or Schizophrenia	0.4	1.0	5.1	1.7	2.0	0.8	1.1	0.9	0.7	0.8	0.7	2.2	0.8	0.9	1.0	0.8	1.0	0.9	0.0	0.8	0.0	0.6	0.9	0.7	0.9	0.8	0.8
Depressed Affect (Nagel 2018)	0.4	0.8	6.7	-0.2	-2.6	-0.3	-1.7	-0.6	-0.6	-0.5	-0.5	0.1	-0.4	-0.5	-0.4	-0.3	-1.5	-1.7	0.7	-0.4	-0.6	0.0	-0.0	-0.5	-0.9	-0.4	-0.7
Prostate Cancer	0.4	0.6	1.5	-0.5	-0.3	-0.2	0.2	-0.8	-0.9	-0.9	-0.9	0.5	-1.0	-0.9	-1.0	-0.7	-0.9	-0.0	-0.2	-0.9	-0.9	-1.0	-1.2	-0.9	-1.1	-1.0	-1.0
Age at First Birth	0.4	0.6	1.9	0.3	1.4	0.9	1.2	0.8	0.8	0.8	0.8	-0.2	0.7	0.8	0.7	-0.1	1.3	-0.1	-0.1	0.6	0.6	-0.1	0.6	0.8	1.1	1.0	0.2
Blood White Count	0.4	2.6	6.2	1.4	0.7	-0.2	0.6	1.9	2.1	2.0	2.0	1.0	1.8	2.0	1.7	0.5	1.9	2.4	0.9	2.4	1.4	1.1	1.4	2.0	2.5	2.0	1.4
Systolic Blood Pressure	0.4	2.1	9.8	-0.4	-1.9	-1.2	-0.5	-1.2	-1.2	-1.3	-1.3	1.0	-1.3	-1.3	-1.2	-3.1	-2.0	-1.5	1.3	-1.2	-2.1	-1.9	-1.2	-1.2	-1.2	-0.7	-2.0
Hypothyroidism (self reported)	0.4	0.8	3.8	0.4	0.7	0.9	1.5	1.0	1.0	1.0	0.9	-0.2	1.2	1.1	1.0	-1.2	-0.5	0.7	2.0	0.8	0.0	0.5	0.8	0.9	0.4	1.1	0.1
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.8	-0.0	-1.1	-0.6	-0.5	0.4	0.6	0.6	0.8	-1.0	0.5	0.4	0.5	0.2	0.5	-0.7	0.1	0.8	0.7	1.7	0.8	0.8	0.7	0.5	1.3
Diabetes (mother)	0.4	0.5	4.7	0.2	2.2	1.1	1.9	-0.3	-0.4	-0.4	-0.3	1.1	-0.5	-0.4	-0.2	-0.9	-0.2	-0.4	-0.3	-0.5	-0.2	-0.2	-0.2	-0.3	-0.1	-0.3	0.2
Medication: Atenolol	0.4	0.5	5.5	-1.0	-1.5	0.3	-1.4	-0.3	-0.2	-0.2	-0.3	-2.4	-0.3	-0.2	-0.3	-0.2	-0.3	-0.9	0.3	-0.2	-0.5	-0.1	-0.3	-0.3	-0.3	-0.2	-0.3
Sitting height	0.4	3.1	7.3	0.8	0.8	-1.8	1.5	1.8	1.8	1.8	1.8	-1.3	1.9	1.7	1.8	2.7	2.4	1.0	1.0	1.8	1.8	2.5	1.9	1.8	2.0	1.6	2.7
Heart attack	0.4	0.5	1.8	-0.8	0.2	-0.0	-0.4	-0.6	-0.7	-0.7	-0.8	-0.5	-1.0	-0.6	-0.8	-1.3	-0.3	-0.2	-0.8	-0.5	-1.2	-0.7	-1.0	-0.8	-0.4	-0.9	-0.5
Pain all over the body in last month	0.4	0.5	4.7	-0.4	2.2	0.5	1.2	-0.6	-0.7	-0.6	-0.4	-0.2	-0.6	-0.8	-0.5	-0.8	-0.1	-0.3	-0.8	-0.5	-0.1	-0.5	-0.3	-0.4	-0.5	-0.4	-0.4
Time employed in main current job	0.4	0.4	3.1	-0.6	1.0	0.4	0.5	-0.2	-0.3	-0.3	-0.3	-0.5	-0.1	-0.2	-0.2	1.8	0.9	-0.4	-1.3	-0.2	0.4	-1.0	-0.2	-0.3	-0.5	-0.0	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	3.1	0.7	-0.1	1.0	0.5	0.3	0.4	0.5	0.7	0.4	0.6	0.3	0.6	1.1	-0.1	-0.4	1.8	0.4	0.4	0.5	0.8	0.8	-0.3	0.8	-0.2
Depression (self-reported)	0.4	0.5	1.6	-0.0	-0.2	0.9	0.3	0.8	0.8	0.8	0.7	-1.3	0.6	0.8	0.6	-0.5	0.4	-0.1	1.1	0.7	0.2	1.1	0.6	0.7	0.4	0.6	0.8
Medication: Lansoprazole	0.4	0.5	3.6	0.1	-0.1	1.9	0.2	-0.5	-0.5	-0.4	-0.6	1.5	-0.6	-0.3	-0.7	-0.8	-0.2	0.0	-1.1	-0.5	-0.3	-0.2	-0.7	-0.6	-0.4	-0.9	-0.1
Impedance of arm (left)	0.4	1.8	3.6	0.7	1.3	-1.9	0.8	1.8	1.7	1.6	1.4	-0.9	1.6	1.7	1.5	1.0	1.7	0.4	-0.2	1.5	1.8	1.4	1.1	1.4	1.5	1.4	1.1
Gout (self-reported)	0.4	0.6	2.2	0.7	1.2	-0.8	1.5	0.5	0.6	0.7	0.6	0.9	0.6	0.7	0.6	0.9	0.9	1.4	-0.8	0.6	1.2	-0.0	0.4	0.6	0.3	0.5	0.2
Birth weight	0.4	0.9	1.5	0.6	-0.2	0.3	0.0	1.2	1.2	1.2	1.1	-1.2	1.2	1.2	1.1	1.2	1.0	0.5	0.8	1.2	0.6	1.1	1.1	1.0	1.2	1.1	1.1
Shortness of breath walking on level ground	0.4	0.5	2.0	-0.9	-0.6	-1.0	0.3	-0.5	-0.6	-0.6	-0.7	-1.4	-0.7	-0.5	-0.6	-0.5	-0.4	-1.2	-0.3	-0.6	-0.7	0.1	-0.8	-0.7	-0.4	-0.9	0.1
Eye problems/disorders: None of the above	0.4	0.4	3.3	-0.3	1.5	0.1	0.7	0.0	0.2	0.1	0.4	-0.1	0.2	0.0	0.0	1.8	0.9	1.5	-0.9	-0.0	0.4	0.1	-0.0	0.4	0.0	-0.0	0.6
Neck or shoulder pain in last month	0.4	0.6	2.8	-0.5	-1.2	1.5	-0.8	-0.7	-0.7	-0.7	-0.8	-0.1	-0.7	-0.6	-0.7	-0.5	-0.6	-1.7	-0.5	-0.7	-0.6	-0.5	-0.7	-0.7	-0.9	-0.6	-0.7
Age at last live birth	0.4	0.6	4.5	0.7	1.5	2.1	1.4	0.7	0.6	0.6	0.4	-0.4	0.6	0.7	0.6	0.6	0.7	-0.3	1.3	0.6	0.4	-0.1	0.4	0.4	0.2	0.8	-0.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.8	-0.5	0.4	-0.9	0.7	-0.8	-0.8	-0.8	-0.8	0.3	-0.9	-0.8	-0.8	-0.5	-0.6	-0.5	-0.9	-0.9	-0.8	-0.8	-0.7	-0.8	-0.6	-0.7	-0.7
Eye problems/disorders: Cataract	0.4	0.5	3.3	-0.3	-1.8	-0.7	-0.9	-0.3	-0.2	-0.3	-0.3	-1.0	-0.4	-0.3	-0.2	-1.1	-0.9	-1.4	0.8	-0.4	-0.5	-0.3	-0.1	-0.3	0.1	0.1	-0.5
Medication for cholesterol	0.4	0.6	2.4	-0.3	-1.0	-0.3	-1.6	0.3	0.4	0.4	0.2	-1.3	0.2	0.5	0.1	0.7	0.5	-0.5	-1.4	0.5	0.1	1.4	-0.1	0.3	1.0	-0.1	1.4
High cholesterol (Self-reported)	0.4	0.8	8.1	1.3	1.3	-0.1	-0.3	0.3	0.4	0.3	0.6	2.9	0.3	0.1	0.3	-0.6	1.3	-0.8	-0.1	0.3	0.6	-0.2	0.3	0.7	1.2	1.1	0.1
Medication: Paracetamol	0.4	0.7	2.5	-0.2	-0.4	0.1	-0.5	0.6	0.7	0.7	0.8	-1.6	0.8	0.5	0.7	0.3	0.6	-1.0	1.1	0.7	0.5	1.4	1.1	0.9	0.8	1.0	1.1
Medication: Atorvastatin	0.4	0.4	1.7	0.2	0.1	0.8	0.6	-0.2	-0.3	-0.4	-0.7	1.3	-0.6	-0.1	-0.4	-1.3	-0.4	-0.9	0.6	-0.4	-0.9	-1.1	-0.6	-0.7	-0.2	-0.2	-0.7
Fractured/broken bones in last 5 years	0.4	0.5	1.7	0.5	-0.2	0.5	-0.0	0.7	0.7	0.7	0.7	0.5	0.6	0.7	0.7	1.2	0.8	-0.3	-0.1	0.8	1.3	0.8	0.8	0.8	0.3	0.7	0.7
Age started oral contraceptive pill	0.4	0.4	2.1	-0.6	-1.3	-1.4	-0.7	-0.4	-0.2	-0.3	-0.1	-1.5	-0.4	-0.4	-0.2	-0.5	-0.7	-0.9	1.1	-0.3	-0.8	-0.1	-0.1	-0.0	-0.5	-0.0	-0.7
Alcohol drinker status: Previous	0.4	0.4	2.6	-0.8	-0.5	-0.9	0.7	-0.5	-0.4	-0.3	-0.3	-0.9	-0.4	-0.4	-0.5	-0.4	-0.6	-1.6	1.1	-0.4	-0.5	-0.2	-0.4	-0.2	-0.9	-0.2	-0.7
Schizophrenia (2018)	0.3	0.6	4.8	1.2	2.2	0.3	1.6	0.7	0.5	0.7	0.6	0.9	0.8	0.8	0.9	0.5	0.7	0.0	0.0	0.6	0.0	0.0	0.9	0.6	0.0	0.0	0.5
Irritable Bowel Disease (IBD)	0.3	0.8	6.7	-0.3	1.5	2.6	-1.7	-0.1	-0.4	-0.6	-0.6	-0.4	-0.6	-0.5	-0.4	0.4	0.6	-0.6	-1.9	-0.4	-0.7	0.1	-0.8	-0.6	-0.0	-0.8	0.4
Ulcerative Colitis (UC)	0.3	0.6	8.2	-0.0	0.9	2.9	-0.9	0.2	0.0	-0.1	-0.3	-0.0	-0.3	0.0	-0.1	0.4	0.9	0.2	-1.7	-0.1	0.2	-0.0	-0.5	-0.3	0.1	-0.4	0.5
Crohns Disease (2012)	0.3	0.5	4.0	0.3	-0.1	2.0	-2.0	0.3	0.2	0.1	0.4	-0.6	0.4	-0.0	0.4	0.3	0.4	0.5	-0.1	0.2	0.2	0.8	0.5	0.3	0.6	0.1	1.0
HbA1C	0.3	0.3	3.3	-1.0	-0.3	-0.7	-0.3	-0.4	-0.4	-0.4	-0.3	-1.8	-0.1	-0.4	-0.4	0.0	-0.5	0.2	-0.6	-0.3	-1.0	-0.4	-0.2	-0.4	-0.7	-0.4	-0.4
Lupus	0.3	0.5	3.8	-1.4	-0.8	-1.9	-0.4	-0.6	-0.6	-0.6	-0.7	-1.7	-0.6	-0.6	-0.6	0.0	-1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.3	0.4	1.4	-0.8	-0.3	1.0	-0.1	-0.4	-0.3	-0.7	-0.2	1.1	-0.9	-0.9	-0.5	0.5	-1.2	0.2	0.0	-0.5	0.0	-0.7	-0.7	-0.3	-0.5	-0.7	-0.9
Smoking Status	0.3	0.6	4.9	-1.0	-1.4	-0.4	-0.7	-0.3	-0.3	-0.3	-0.3	-2.2	-0.1	-0.2	-0.2	-1.1	-1.7	-0.7	0.7	-0.3	-0.6	0.2	0.1	-0.4	-0.4	-0.3	-0.1
Tanning	0.3	3.1	6.6	1.2	1.6	-0.5	1.0	2.2	2.2	2.1	2.3	-0.6	1.5	2.0	2.0	1.2	2.2	2.3	0.4	2.6	2.2	1.7	1.6	2.2	1.4	1.8	1.9
Medication for hormone replacement therapy	0.3	0.4	1.4	0.4	0.7	-1.1	1.1	-0.1	-0.1	-0.2	-0.1	1.2	-0.2	-0.2	-0.1	-0.6	-0.6	1.0	0.9	-0.1	-0.5	-0.9	-0.1	-0.1	-0.5	-0.1	-1.0
Medication: Metformin	0.3	0.4	2.8	0.3	0.7	0.7	0.6	-0.0	-0.1	-0.2	-0.3	1.2	-0.5	-0.1	-0.3	-1.2	0.3	-0.2	-1.7	-0.3	-0.1	-0.3	-0.6	-0.4	0.5	-0.3	0.4
Multivitamins +/- minerals	0.3	0.3	2.8	-0.0	1.3	-1.4	1.7	0.2	0.2	0.2	0.1	-0.2	0.1	0.2	-0.1	0.2	0.4	0.3	-0.9	0.0	0.7	-0.4	-0.4	0.1	0.1	0.1	0.1
Supplements: Glucosamine	0.3	0.3	3.3	-0.0	1.4	-1.8	0.1	-0.2	-0.3	-0.2	-0.1	-0.0	-0.2	-0.3	-0.1	-1.2	-0.6	-0.6	0.6	-0.0	-0.2	-0.0	0.0	-0.0	-0.1	-0.1	-0.3
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	0.5	-1.1	0.2	0.8	0.4	0.6	0.6	0.7	0.2	0.6	0.6	0.3	1.0	0.6	0.5	-0.2	0.6	1.0	0.8	0.2	0.7	-0.0	0.3	0.7
Worrier / anxious feelings	0.3	0.5	1.0	-0.7	0.8	-0.9	1.0	-0.5	-0.6	-0.6	-0.9	0.1	-0.7	-0.4	-0.7	0.3	-0.9	-0.6	-0.8	-0.5	-1.0	-0.3	-1.0	-0.9	-0.5	-0.9	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	3.5	-0.5	0.2	0.3	0.6	0.3	0.3	0.3	0.5	-1.9	0.4	0.2	0.4	-0.6	0.0	-1.4	0.9	0.4	0.4	0.9	0.6	0.5	0.3	0.6	0.8
Happiness	0.3	0.3	2.0	0.1	1.4	1.1	1.3	0.5	0.4	0.4	0.2	-0.8	0.2	0.5	0.3	-0.1	0.3	-0.2	-0.5	0.4	0.8	0.5	-0.0	0.2	0.1	0.1	0.6
Noisy workplace	0.3	0.4	2.7	-0.8	0.1	0.2	1.6	0.1	-0.1	-0.0	-0.6	-1.3	-0.2	0.3	0.0	-0.4	-0.9	-0.8	0.8	-0.2	-0.8	0.2	-0.3	-0.6	-0.6	-0.5	0.4
Prospective memory result	0.3	0.4	1.0	0.5	-0.7	-1.0	-0.7	0.7	0.8	0.8	0.7	-0.0	0.5	0.7	0.7	-0.1	0.9	-0.0	0.6	0.7	0.3	0.7	0.7	0.8	0.6	0.8	0.4
Hair/balding pattern: Pattern 4	0.3	0.7	2.2	-0.4	0.4	1.5	0.3	-0.8	-0.8	-0.8	-0.9	0.2	-1.0	-0.8	-0.9	-0.2	-1.1	-1.2	-0.4	-0.8	-0.7	-0.8	-1.1	-0.9	-1.4	-0.9	-0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.5	0.4	-0.1	0.9	0.5	0.4	0.4	0.4	0.3	0.3	0.5	0.4	0.4	1.2	1.2	0.7	-0.6	0.3	0.8	0.7	0.5	0.4	0.4	0.1	0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.6	0.8	0.1	-1.6	0.4	0.2	0.3	0.3	0.7	0.7	0.2	0.1	0.4	-0.8	0.2	-0.1	1.1	0.4	0.4	0.0	0.4	0.7	0.4	0.8	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.0	-0.1	-0.6	-0.8	0.3	-0.7	-0.6	-0.7	-0.3	-0.2	-0.5	-0.8	-0.5	-0.6	-0.4	-0.5	0.5	-0.6	-0.2	-0.8	-0.3	-0.3	-1.0	-0.2	-1.0
High blood pressure (siblings)	0.3	0.4	2.3	-0.2	-0.5	0.7	-0.0	-0.6	-0.5	-0.5	-0.4	-0.2	-0.7	-0.6	-0.5	-1.5	-0.9	-1.0	1.1	-0.7	-0.7	-0.4	-0.3	-0.3	-0.7	-0.3	-0.8
Wheeze or whistling in the chest in last year	0.3	0.5	4.0	-0.4	1.9	0.7	2.0	-0.4	-0.6	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.3	-0.3	-0.2	-0.5	-0.1	-0.3	-0.6	-0.5	-0.5	-0.6	-0.0
Number of children fathered	0.3	0.3	2.3	-0.7	-0.7	-1.1	-0.2	0.3	0.3	0.3	0.3	-1.5	0.4	0.4	0.2	0.3	0.5	0.8	-0.8	0.3	0.5	0.4	0.2	0.3	-0.2	0.0	0.1
Heart disease (mother)	0.3	0.4	1.7	-0.0	-0.2	-0.9	0.9	-0.4	-0.4	-0.4	-0.4	0.9	-0.7	-0.4	-0.4	0.5	0.1	-0.7	-1.0	-0.4	0.8	-0.9	-0.5	-0.4	-1.3	-0.3	-1.1
Comparative height size at age 10	0.3	1.8	11.4	-0.9	0.4	-3.2	1.2	0.9	0.9	0.9	0.8	-3.4	1.1	0.9	1.0	2.3	0.6	-0.6	1.4	0.6	1.0	1.5	1.0	0.8	0.3	0.8	1.3
Suffer from ‘nerves’	0.3	0.5	2.0	-0.6	-0.9	-1.4	-1.0	-0.4	-0.4	-0.4	-0.6	0.1	-0.7	-0.3	-0.6	-1.1	-1.1	0.1	-0.2	-0.3	-1.1	-0.6	-0.9	-0.7	-0.7	-0.7	-0.8
Long-standing illness, disability or infirmity	0.3	0.4	3.2	0.1	1.4	0.0	1.8	-0.2	-0.3	-0.4	-0.5	0.8	-0.5	-0.3	-0.4	-0.6	-0.4	-0.9	-0.2	-0.5	-0.3	-0.2	-0.6	-0.5	-0.4	-0.4	-0.0
Ever had bowel cancer screening	0.3	0.3	1.7	-0.3	0.3	-0.3	-0.5	-0.4	-0.4	-0.4	-0.4	0.0	-0.5	-0.3	-0.6	-1.3	-0.5	0.0	-0.6	-0.4	-1.0	-0.9	-0.9	-0.4	-0.4	-0.4	-0.9
Commuting to job workplace: Walk	0.3	0.4	2.0	0.7	0.5	-0.3	0.6	0.4	0.4	0.4	0.4	1.4	0.3	0.3	0.4	-0.8	1.0	-0.4	-0.5	0.2	0.8	0.4	0.5	0.5	0.9	0.6	0.6
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.9	0.3	0.4	-0.7	0.8	0.7	0.6	0.5	0.5	-0.2	0.6	0.6	0.8	1.4	-0.1	-0.4	1.2	0.5	0.7	0.5	0.7	0.4	-0.3	0.6	0.3
Medication: Blood pressure	0.3	0.5	1.7	-0.1	-0.3	0.4	0.4	-0.9	-0.9	-0.9	-0.7	0.5	-0.7	-1.0	-0.6	-0.2	-0.8	-0.3	0.9	-1.0	-0.3	-1.0	-0.1	-0.7	-1.3	-0.5	-1.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	3.1	-0.7	-1.8	0.3	-0.6	-0.3	-0.1	-0.1	-0.0	-1.2	-0.2	-0.2	-0.4	-0.7	-0.7	-0.4	0.0	-0.3	-0.1	0.8	-0.4	0.0	-0.8	-0.5	-0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.1	-0.6	1.5	-1.2	0.4	-0.1	-0.2	-0.2	-0.4	-0.1	-0.3	-0.2	-0.3	-1.5	-0.3	-0.2	-1.0	-0.3	-0.4	0.3	-0.6	-0.3	0.2	-0.6	0.7
Ever smoked	0.3	0.5	1.5	-0.9	-0.9	-0.2	0.0	-0.5	-0.6	-0.6	-0.7	-1.2	-0.7	-0.6	-0.6	-0.5	-1.0	-1.1	-1.1	-0.6	-0.4	0.2	-0.4	-0.7	-0.2	-0.8	0.3
Arm fat-free mass (left)	0.3	1.3	6.4	-1.9	-1.3	-0.2	-0.5	-1.5	-1.3	-1.3	-1.0	-2.5	-1.1	-1.4	-1.1	0.5	-1.1	-0.7	0.2	-1.4	-1.3	-0.2	-0.6	-1.0	-1.3	-1.3	-0.3
Irritability	0.3	0.5	2.8	-0.5	-1.1	0.2	-1.7	-0.6	-0.6	-0.7	-0.6	-0.8	-0.5	-0.7	-0.5	0.0	-0.2	-1.3	-0.4	-0.6	-0.7	-0.3	-0.2	-0.6	-0.2	-0.4	-0.5
Arm predicted mass (left)	0.3	1.6	7.3	-2.1	-1.5	-0.2	-0.8	-1.6	-1.4	-1.4	-1.2	-2.7	-1.2	-1.5	-1.2	0.5	-1.1	-0.7	-0.0	-1.5	-1.4	-0.3	-0.8	-1.2	-1.4	-1.4	-0.4
Schizophrenia vs Biploar Disorder	0.2	0.2	0.6	-0.1	0.3	-0.6	-0.2	-0.7	-0.7	-0.6	-0.5	-0.4	-0.5	-0.6	-0.5	-0.1	-0.7	-0.8	0.0	-0.7	0.0	-0.3	-0.3	-0.5	-0.5	-0.4	-0.6
Crohns Disease (2017)	0.2	0.5	3.4	-0.3	0.7	0.7	-1.9	-0.4	-0.6	-0.7	-0.7	-0.1	-0.5	-0.7	-0.5	0.0	0.0	-0.9	-1.1	-0.5	-1.3	0.2	-0.7	-0.7	0.1	-0.8	0.4
Major Depression (MDD)	0.2	0.3	2.5	-0.4	0.1	0.6	-0.2	-0.5	-0.6	-0.2	-0.6	0.4	-0.4	0.1	-0.6	-0.0	-0.1	0.2	-1.6	-0.3	-0.5	-0.0	-0.8	-0.7	-0.3	-0.9	0.3
Breast Cancer	0.2	0.5	3.6	-0.8	-0.4	-0.1	-0.3	-0.4	-0.3	-0.4	-0.5	-0.7	-0.5	-0.3	-0.5	-1.9	-1.1	-0.9	0.1	-0.3	-0.5	-0.7	-0.8	-0.4	-0.8	-0.4	-1.1
Coronary Artery Disease (CAD)	0.2	0.2	0.9	-0.3	-1.0	0.6	-0.8	-0.2	-0.2	-0.5	-0.3	0.0	-0.3	-0.5	-0.2	0.3	-0.1	-0.6	0.0	0.0	0.0	0.6	-0.1	-0.3	0.3	-0.4	0.9
Height	0.2	3.0	53.4	-2.5	0.1	-1.3	1.5	0.3	0.4	0.4	0.7	-7.3	0.6	0.2	0.5	1.5	0.8	0.4	1.4	0.1	0.8	1.0	1.0	0.6	0.1	0.5	0.7
Leg fat-free mass (left)	0.2	1.1	4.3	-1.8	-0.9	-0.1	0.2	-1.4	-1.3	-1.2	-1.0	-2.1	-1.1	-1.3	-1.1	0.6	-0.9	-0.5	-0.6	-1.3	-0.8	-0.3	-0.7	-1.0	-1.4	-1.3	-0.5
Townsend deprivation index at recruitment	0.2	0.3	2.4	0.3	0.8	0.8	1.0	-0.3	-0.2	-0.2	-0.1	1.6	-0.4	-0.2	-0.3	-0.1	0.2	-0.3	-1.4	-0.5	0.9	-0.2	-0.3	-0.1	-0.5	-0.2	-0.1
Leg predicted mass (left)	0.2	1.2	4.4	-1.9	-0.9	-0.2	0.3	-1.4	-1.3	-1.2	-1.0	-2.1	-1.1	-1.4	-1.1	0.6	-0.9	-0.5	-0.5	-1.3	-0.8	-0.4	-0.7	-1.0	-1.5	-1.3	-0.5
Financial difficulties in last 2 years	0.2	0.3	1.0	0.4	0.0	-0.7	-0.1	0.3	0.4	0.5	0.8	-0.4	0.5	0.3	0.6	-0.3	0.3	-0.3	0.5	0.3	1.0	0.5	0.8	0.8	0.5	0.8	-0.1
Medication: Simvastatin	0.2	0.3	2.6	0.3	1.5	1.6	0.0	-0.1	-0.1	-0.1	0.2	0.2	0.1	-0.3	-0.0	-0.6	0.4	-0.4	-0.1	0.0	0.3	-0.4	0.1	0.2	0.1	0.4	-0.4
Illnesses of siblings	0.2	0.3	0.8	0.0	-0.1	-0.9	0.2	0.6	0.6	0.6	0.4	-0.5	0.8	0.6	0.6	0.5	-0.1	0.5	0.5	0.7	0.3	0.6	0.6	0.4	0.5	0.4	0.6
Impedance of arm (right)	0.2	1.2	2.0	0.4	1.0	-1.4	0.5	1.4	1.3	1.2	1.0	-1.4	1.3	1.3	1.2	1.2	1.4	-0.1	0.1	1.1	1.4	1.1	1.0	1.0	1.1	1.2	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.8	-0.7	-0.2	0.5	-0.3	-0.4	-0.4	-0.5	-0.6	-0.4	-0.7	-0.4	-0.6	-1.0	-0.3	0.1	-1.4	-0.3	-0.4	0.0	-0.8	-0.6	-0.2	-0.9	0.2
Loud music exposure frequency	0.2	0.2	1.6	-0.1	-0.2	1.3	-0.1	0.2	0.3	0.3	0.3	-0.0	0.4	0.2	0.4	0.7	0.1	0.3	-0.8	0.3	0.5	0.8	0.5	0.3	0.4	0.1	1.0
Medication: Paracetamol	0.2	0.3	1.6	-0.4	-0.3	-0.5	-0.2	0.2	0.3	0.3	0.4	-1.2	0.4	0.2	0.4	-0.4	0.2	-1.3	0.9	0.3	0.1	0.8	0.7	0.5	0.7	0.7	0.7
Arm fat-free mass (right)	0.2	1.2	5.7	-1.9	-1.3	-0.6	-0.4	-1.4	-1.2	-1.2	-0.9	-2.4	-1.0	-1.3	-1.0	0.2	-1.1	-0.6	0.3	-1.2	-1.2	-0.2	-0.6	-0.9	-1.3	-1.1	-0.3
Comparative body size at age 10	0.2	0.5	4.0	0.6	0.4	0.6	0.0	0.3	0.4	0.5	0.7	0.9	0.4	0.3	0.4	1.0	0.7	2.0	-1.0	0.3	1.1	0.2	0.6	0.7	0.5	0.4	0.3
Pulse wave peak to peak time	0.2	0.3	1.6	-0.2	0.1	0.4	-0.5	0.4	0.5	0.4	0.6	-1.3	0.5	0.4	0.5	0.7	-0.1	-0.0	-0.3	0.4	1.0	0.7	0.6	0.6	0.1	0.4	0.0
Medication for pain relief, constipation, heartburn	0.2	0.3	1.9	0.6	-0.0	0.3	-0.5	-0.2	-0.3	-0.2	-0.3	1.4	-0.2	-0.2	-0.3	0.9	0.2	0.9	-1.3	-0.2	0.4	-0.4	-0.3	-0.4	-0.3	-0.5	0.0
Arm predicted mass (right)	0.2	1.0	6.4	-1.8	-1.5	-0.4	-0.5	-1.2	-1.0	-1.0	-0.8	-2.5	-0.8	-1.1	-0.9	0.5	-1.0	-0.5	0.4	-1.0	-1.1	0.0	-0.5	-0.7	-1.1	-1.0	-0.1
Leg pain on walking	0.2	0.2	1.6	0.7	-1.0	0.1	0.1	0.1	0.1	0.2	0.1	-0.0	0.2	0.2	0.2	-0.5	-0.7	-0.5	1.3	0.0	-0.2	0.8	0.5	0.1	0.1	0.1	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	2.3	0.3	1.5	1.2	-0.1	-0.1	-0.1	-0.0	0.2	0.6	-0.0	-0.2	-0.1	-0.1	0.1	0.2	-1.0	-0.1	0.2	0.4	0.0	0.2	0.2	-0.1	0.3
Average weekly red wine intake	0.2	0.3	1.7	-0.4	0.5	-0.8	-0.1	-0.5	-0.5	-0.5	-0.5	-0.8	-0.5	-0.6	-0.5	-1.2	-0.4	-1.3	-0.0	-0.4	-0.1	-0.5	-0.4	-0.5	-0.4	-0.3	-0.5
Friendships satisfaction	0.2	0.3	2.8	0.2	-0.1	1.1	-0.1	0.1	0.0	0.1	-0.1	0.1	-0.1	0.2	-0.1	0.8	0.1	0.8	-1.7	0.2	-0.1	0.4	-0.3	-0.3	0.3	-0.5	0.7
Osteoporosis (self-reported)	0.2	0.3	1.5	0.3	1.1	-0.2	1.2	0.6	0.4	0.5	0.3	0.3	0.6	0.5	0.4	-0.5	0.6	0.2	-0.6	0.5	0.8	-0.3	0.2	0.3	0.3	0.5	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	1.5	-0.4	-0.4	0.1	-1.2	-0.2	-0.2	-0.2	0.0	-1.1	0.1	-0.3	0.1	0.3	-0.2	-0.5	0.4	-0.2	-0.2	0.8	0.7	0.0	0.4	-0.0	0.5
Number of self-reported non-cancer illnesses	0.2	0.3	2.4	0.3	0.8	0.5	0.7	0.3	0.2	0.1	0.1	0.2	0.2	0.1	0.3	-1.5	-0.6	-0.6	1.5	0.1	-0.7	0.3	0.3	0.2	0.7	0.4	0.3
Miserableness	0.2	0.3	2.2	-0.1	-1.5	-0.1	-0.2	-0.3	-0.3	-0.3	-0.3	0.6	-0.3	-0.3	-0.3	-1.1	-1.0	-0.8	0.3	-0.2	-0.4	-0.2	-0.1	-0.3	-0.2	-0.1	-0.4
Wears glasses or contact lenses	0.2	0.2	1.5	0.4	0.3	1.2	-0.3	0.5	0.4	0.4	0.4	0.0	0.2	0.4	0.4	0.3	0.8	0.4	0.0	0.4	0.9	-0.1	0.3	0.4	0.0	0.4	0.1
Financial situation satisfaction	0.2	0.2	1.0	0.5	0.8	0.6	1.0	0.2	0.2	0.3	0.3	-0.0	0.3	0.3	0.4	-0.6	-0.2	0.0	0.9	0.1	0.5	-0.2	0.4	0.3	-0.2	0.4	-0.3
Basal metabolic rate	0.2	0.9	6.5	-1.8	-1.1	-0.2	-0.0	-1.1	-1.0	-0.9	-0.7	-2.5	-0.8	-1.0	-0.8	0.9	-0.7	-0.4	-0.0	-1.0	-0.7	0.0	-0.4	-0.7	-1.1	-1.0	-0.1
Number of operations (self-reported)	0.2	0.3	0.9	-0.3	0.6	0.9	0.4	-0.3	-0.5	-0.6	-0.5	0.6	-0.5	-0.5	-0.6	0.0	-0.2	0.1	-0.9	-0.6	-0.3	-0.9	-0.7	-0.6	-0.5	-0.5	-0.3
Heart disease (siblings)	0.2	0.3	1.3	0.6	-0.8	-0.6	-0.5	-0.1	-0.2	-0.2	-0.2	1.2	-0.2	-0.2	-0.2	0.0	0.6	1.1	-0.9	-0.2	0.5	-0.7	-0.3	-0.2	-0.4	-0.3	-0.5
Impedance of whole body	0.2	1.0	4.1	0.2	0.4	-2.0	-0.1	1.3	1.2	1.1	1.0	-1.6	1.1	1.2	1.0	0.2	0.8	-0.3	0.5	1.1	1.0	1.2	0.7	1.0	0.8	0.9	0.7
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.7	-0.0	0.2	-1.1	0.7	-0.1	-0.1	-0.2	-0.2	1.3	-0.3	-0.3	-0.2	-1.0	0.1	-0.8	0.1	-0.1	-0.1	-0.5	-0.4	-0.1	-0.4	-0.1	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.9	0.4	-0.9	-0.4	-0.9	-0.0	-0.1	-0.1	-0.1	0.6	-0.0	-0.0	0.1	0.3	-0.7	-0.9	1.0	0.1	-0.6	0.2	0.4	-0.2	-0.2	0.1	-0.2
Worry (Nagel 2018)	0.1	0.1	1.4	-0.1	0.2	-1.2	-0.1	0.0	-0.1	-0.2	-0.3	-0.2	-0.1	-0.0	0.0	0.6	-0.3	-0.2	0.4	-0.0	-0.6	0.1	-0.0	-0.4	-0.1	-0.2	0.2
Ovarian Cancer	0.1	0.1	0.7	-0.0	0.4	0.8	0.4	-0.1	-0.0	-0.0	0.2	0.0	0.0	-0.1	-0.2	0.3	-0.2	0.7	0.3	0.1	0.1	-0.7	-0.2	0.1	-0.3	0.2	-0.8
Primary Biliary Cirrhosis	0.1	0.2	1.4	-0.3	1.0	0.6	1.2	-0.2	-0.1	-0.1	0.1	-0.3	-0.0	-0.2	-0.1	0.1	0.6	0.2	0.0	-0.2	-0.4	-0.2	-0.0	0.1	0.6	0.2	0.2
Waist Hip Ratio (WHR)	0.1	0.3	1.9	0.1	-0.5	0.5	0.6	0.4	0.5	0.5	0.6	-0.9	0.5	0.4	0.5	0.0	0.1	-0.3	1.4	0.4	0.5	0.3	0.7	0.6	0.5	0.9	0.2
Lung FEV1/FVC ratio	0.1	0.5	2.4	-0.1	-1.4	-0.2	0.7	-0.6	-0.4	-0.3	-0.3	0.7	-0.3	-0.3	-0.5	-0.5	-1.6	-0.6	1.1	-0.4	-0.1	-0.4	-0.4	-0.3	-1.4	-0.3	-0.7
Neuroticism	0.1	0.2	1.6	0.4	-0.3	-0.2	-1.3	0.3	0.4	0.4	0.4	0.5	0.3	0.3	0.4	0.2	-0.0	-0.8	0.3	0.5	0.2	0.7	0.4	0.4	0.5	0.6	0.5
Hair Pigment	0.1	4.0	18.4	3.5	2.6	0.3	0.8	1.8	1.7	1.8	1.8	4.3	1.9	1.8	1.9	0.6	2.5	1.5	0.7	1.5	1.9	1.5	2.0	1.8	2.6	2.0	2.2
Impedance of leg (right)	0.1	0.6	1.8	0.4	-0.1	-0.6	-1.4	1.0	0.9	0.8	0.8	-1.3	0.8	0.8	0.8	0.1	0.4	-0.3	0.9	0.8	0.6	1.1	0.6	0.8	0.8	0.8	0.6
Fed-up feelings	0.1	0.3	1.0	1.0	-0.2	0.4	-0.0	0.5	0.5	0.5	0.6	0.9	0.6	0.5	0.5	0.3	0.0	-0.2	0.4	0.7	0.7	0.4	0.7	0.5	0.3	0.7	0.3
Taking other prescription medications	0.1	0.2	1.2	0.9	0.6	0.9	0.3	0.3	0.3	0.3	0.2	1.1	0.2	0.4	0.2	-0.6	0.1	-0.4	0.9	0.3	-0.3	0.2	0.0	0.2	0.2	0.4	0.2
High blood pressure (mother)	0.1	0.2	1.2	0.0	0.3	1.1	-0.2	0.3	0.3	0.3	0.5	-0.7	0.3	0.2	0.4	0.4	0.5	-0.2	0.1	0.2	0.7	0.7	0.5	0.5	0.0	0.4	0.4
Impedance of leg (left)	0.1	0.7	2.3	0.3	0.0	-1.3	-0.7	1.1	1.0	1.0	0.9	-1.5	1.0	1.0	0.9	-0.1	0.3	-0.2	1.4	0.9	0.5	1.0	0.7	0.9	0.6	0.9	0.5
Nervous feelings	0.1	0.2	1.6	-0.1	1.3	-0.3	0.2	-0.0	-0.2	-0.2	-0.3	-0.1	-0.3	-0.1	0.0	0.9	-0.2	-0.6	-0.2	-0.4	-0.3	0.1	-0.1	-0.4	-0.3	-0.3	0.1
Hearing difficulty/problems with background noise	0.1	0.2	1.3	0.5	1.1	1.1	0.2	0.0	-0.0	-0.1	0.1	0.9	-0.0	-0.2	0.2	0.3	-0.2	-0.8	0.3	-0.0	0.3	0.2	0.5	0.1	0.0	0.3	-0.1
Fluid intelligence score	0.1	0.2	0.7	0.3	0.7	-0.1	0.6	-0.1	-0.1	-0.2	0.0	0.7	-0.0	-0.4	-0.1	0.9	0.8	-0.2	-0.2	-0.1	-0.0	-0.6	0.1	0.0	0.1	0.2	-0.6
Neuroticism score	0.1	0.3	2.2	-0.5	-0.4	-1.5	-0.3	-0.3	-0.3	-0.4	-0.4	-0.4	-0.5	-0.3	-0.3	-0.1	-0.7	-1.2	0.0	-0.1	-0.4	0.1	-0.3	-0.4	-0.4	-0.3	-0.2
Trunk fat-free mass	0.1	0.5	4.3	-0.7	-0.9	0.1	-0.4	-0.1	0.1	0.1	0.4	-2.1	0.4	0.0	0.2	1.7	0.4	0.3	0.6	0.0	0.2	0.9	0.6	0.4	0.2	0.2	0.9
Falls in the last year	0.1	0.2	1.3	-0.0	0.3	-0.5	0.9	0.2	0.2	0.2	0.4	-0.9	0.3	0.1	0.3	-0.5	-0.4	-0.2	1.1	0.1	0.1	-0.0	0.4	0.3	0.1	0.6	-0.1
Pulse wave Arterial Stiffness index	0.1	0.2	0.9	0.1	-0.1	-0.5	0.5	-0.3	-0.3	-0.3	-0.5	0.8	-0.4	-0.2	-0.4	-0.5	0.2	-0.0	0.2	-0.3	-0.9	-0.4	-0.5	-0.4	0.0	-0.3	0.2
Trunk predicted mass	0.1	0.5	4.2	-0.7	-0.8	0.1	-0.3	-0.0	0.1	0.2	0.4	-2.1	0.4	0.0	0.3	1.7	0.5	0.3	0.6	0.1	0.2	0.9	0.7	0.4	0.3	0.2	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	1.0	0.3	0.0	-0.6	0.1	-0.1	-0.2	-0.2	-0.2	0.6	0.0	-0.1	-0.3	-0.2	-0.0	0.2	-0.2	-0.2	-0.2	-1.0	-0.4	-0.3	-0.3	-0.0	-0.8
Health satisfaction	0.1	0.2	1.7	-0.2	0.5	1.3	0.9	0.1	0.1	0.1	0.0	-0.6	-0.1	0.2	0.1	0.3	0.2	-0.2	0.3	0.1	0.2	0.2	-0.0	0.0	-0.1	0.0	0.5
Medication: Omeprazole	0.1	0.1	0.9	-0.4	-0.2	0.2	0.3	-0.3	-0.2	-0.2	-0.1	-0.6	-0.2	-0.3	-0.3	-1.0	-0.4	-0.0	-0.1	-0.3	-0.1	-0.3	-0.1	-0.0	-0.2	-0.1	-0.5
Chest pain or discomfort	0.1	0.1	1.1	-0.2	0.2	-1.0	-0.2	-0.0	-0.0	-0.1	0.0	-0.2	-0.2	-0.2	-0.1	-0.3	0.4	-0.3	-0.6	0.1	-0.1	0.2	-0.1	0.1	0.5	-0.0	0.4
Whole body fat-free mass	0.1	0.4	4.5	-1.1	-0.9	0.1	-0.2	-0.5	-0.4	-0.3	-0.1	-2.1	-0.1	-0.4	-0.2	1.3	-0.1	0.0	0.3	-0.4	-0.2	0.5	0.2	-0.1	-0.4	-0.3	0.5
Leg fat-free mass (right)	0.1	0.7	3.8	-1.6	-0.7	-0.4	0.6	-1.1	-1.0	-0.9	-0.7	-2.0	-0.7	-1.0	-0.8	0.8	-0.6	-0.3	-0.1	-1.0	-0.5	-0.2	-0.4	-0.7	-1.1	-0.9	-0.2
Back pain experienced in last month	0.1	0.1	0.8	0.2	-0.9	0.6	0.1	0.1	0.1	0.1	0.2	-0.5	-0.0	0.0	0.1	-0.4	0.1	0.1	0.0	-0.0	0.1	0.3	0.3	0.2	0.3	0.1	0.3
Whole body water mass	0.1	0.4	4.9	-1.2	-1.0	-0.2	-0.1	-0.6	-0.5	-0.4	-0.2	-2.2	-0.2	-0.5	-0.3	1.2	-0.2	-0.0	0.3	-0.5	-0.3	0.5	0.1	-0.2	-0.5	-0.4	0.4
Leg predicted mass (right)	0.1	0.8	4.0	-1.6	-0.7	-0.4	0.7	-1.1	-1.0	-0.9	-0.7	-2.0	-0.8	-1.0	-0.8	0.8	-0.7	-0.4	-0.2	-1.0	-0.5	-0.2	-0.4	-0.7	-1.2	-0.9	-0.3
Illnesses of father: High blood pressure	0.1	0.2	0.9	0.3	-0.3	-0.0	-0.9	-0.3	-0.4	-0.3	-0.3	1.0	-0.3	-0.3	-0.3	0.6	0.2	-0.1	-0.1	-0.6	-0.5	-0.3	-0.4	-0.3	-0.1	-0.3	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	1.1	-0.1	0.2	0.6	0.2	-0.2	-0.3	-0.2	-0.2	-0.1	-0.3	-0.3	-0.3	-1.0	-0.5	0.1	-0.0	-0.3	-0.2	-0.4	-0.2	-0.2	-0.2	-0.3	-0.7
Blood Platelet Count	0.0	0.4	3.5	-0.1	1.6	-0.1	1.9	0.3	0.2	0.1	-0.1	0.3	-0.0	0.3	0.0	0.7	-0.1	1.1	-0.6	0.3	-0.2	0.2	-0.4	-0.2	0.1	-0.4	0.4
Age when periods started (menarche)	0.0	0.1	0.3	-0.6	0.5	0.4	0.0	0.2	0.2	0.1	-0.1	-0.6	0.1	0.2	0.0	0.1	0.2	0.1	-0.4	0.3	-0.3	0.1	-0.3	-0.0	0.4	-0.1	0.3
Medication: Lisinopril	0.0	0.1	0.3	0.0	-0.4	0.0	0.1	-0.1	-0.1	-0.1	0.0	-0.2	-0.1	-0.2	-0.0	-0.3	0.2	-0.2	0.3	-0.3	0.5	-0.1	0.0	0.1	-0.5	-0.0	-0.4

Hub : Genes

DARS

Models

Trait associations