Best TWAS P=8.46e-09 · Best GWAS P=4.1e-10 conditioned to 0.00271
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | WFS1 | 0.10 | 0.03 | lasso | 2 | 0.02 | 4.8e-04 | -5.2 | 5.2 | 2.5e-07 | -0.82 | 0.20 | 0.70 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | WFS1 | 0.72 | 0.49 | lasso | 13 | 0.47 | 1.3e-13 | -4.9 | 5.4 | 6.4e-08 | -0.81 | 0.27 | 0.72 | FALSE |
| 3 | GTEx | Brain Cerebellum | WFS1 | 0.44 | 0.26 | lasso | 10 | 0.27 | 9.8e-09 | -4.9 | 5.2 | 1.6e-07 | -0.81 | 0.29 | 0.70 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | WFS1 | 0.22 | 0.04 | enet | 25 | 0.08 | 2.6e-06 | -5.1 | 5.3 | 1.3e-07 | -0.81 | 0.07 | 0.92 | FALSE |
| 5 | METSIM | Adipose | WFS1 | 0.06 | 0.01 | enet | 14 | 0.02 | 1.5e-04 | -5.1 | 5.8 | 8.5e-09 | -0.73 | 0.02 | 0.97 | TRUE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | WFS1 | 0.07 | 0.10 | lasso | 3 | 0.10 | 2.6e-11 | -5.2 | 5.5 | 4.8e-08 | -0.84 | 0.22 | 0.78 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | WFS1 | 0.04 | 0.01 | blup | 76 | 0.01 | 1.6e-02 | -5.2 | 5.5 | 3.1e-08 | -0.84 | 0.06 | 0.88 | FALSE |