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chr4:507,001-2,058,475

Best TWAS P=5.07e-10 · Best GWAS P=4.81e-12 conditioned to 0.00162

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	UVSSA	0.30	0.14	enet	44	0.28	1.4e-22	-5.00	5.1	3.1e-07	-0.62	0.64	0.36	FALSE
2	GTEx	Adrenal Gland	CTBP1-AS2	0.23	0.23	lasso	5	0.19	1.7e-07	-5.15	-5.4	5.3e-08	0.88	0.62	0.34	FALSE
3	GTEx	Artery Aorta	UVSSA	0.33	0.06	enet	30	0.28	7.2e-16	4.13	5.5	3.1e-08	-0.54	0.27	0.71	FALSE
4	GTEx	Artery Tibial	UVSSA	0.27	0.01	enet	40	0.14	1.9e-11	-2.84	5.2	1.5e-07	-0.34	0.72	0.20	FALSE
5	GTEx	Artery Tibial	CRIPAK	0.42	0.09	enet	50	0.34	1.3e-27	-5.00	5.2	2.2e-07	-0.43	0.95	0.05	FALSE
6	GTEx	Brain Cerebellar Hemisphere	CTBP1-AS2	0.54	0.35	enet	11	0.34	1.1e-09	-4.91	-5.2	1.8e-07	0.88	0.29	0.71	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	UVSSA	0.24	0.00	enet	33	0.04	2.8e-02	-5.21	5.2	1.9e-07	-0.49	0.03	0.61	FALSE
8	GTEx	Breast Mammary Tissue	MAEA	0.35	0.07	enet	58	0.24	1.1e-12	-4.43	-6.0	2.4e-09	0.54	0.39	0.61	FALSE
9	GTEx	Breast Mammary Tissue	UVSSA	0.23	0.07	enet	30	0.24	1.5e-12	2.75	5.6	1.8e-08	-0.59	0.10	0.89	FALSE
10	GTEx	Breast Mammary Tissue	CRIPAK	0.42	0.12	enet	35	0.39	5.2e-21	1.84	5.1	2.7e-07	-0.35	0.98	0.01	FALSE
11	GTEx	Breast Mammary Tissue (Male)	MAEA	0.42	0.15	lasso	10	0.23	4.7e-06	-4.43	-5.2	2.0e-07	0.62	0.04	0.89	FALSE
12	GTEx	Breast Mammary Tissue (Male)	CRIPAK	0.21	-0.01	enet	17	0.03	7.1e-02	3.14	5.3	1.1e-07	-0.54	0.04	0.54	FALSE
13	GTEx	Breast Mammary Tissue (Female)	UVSSA	0.21	0.02	enet	24	0.05	1.3e-02	2.85	5.4	7.9e-08	-0.45	0.06	0.35	FALSE
14	GTEx	Cells Transformed fibroblasts	UVSSA	0.28	0.13	enet	43	0.20	4.8e-15	-5.15	5.5	3.7e-08	-0.77	0.27	0.73	FALSE
15	GTEx	Colon Transverse	UVSSA	0.29	0.17	enet	28	0.23	2.1e-11	2.75	5.5	3.2e-08	-0.56	0.44	0.53	FALSE
16	GTEx	Lung	UVSSA	0.42	0.12	lasso	15	0.26	3.2e-20	2.75	5.3	9.5e-08	-0.67	0.97	0.03	FALSE
17	GTEx	Muscle Skeletal	UVSSA	0.15	0.07	lasso	7	0.07	5.2e-07	-4.81	5.9	2.7e-09	-0.77	0.90	0.08	FALSE
18	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	1.84	5.2	2.0e-07	-0.50	0.99	0.01	FALSE
19	GTEx	Nerve Tibial	CTBP1	0.09	0.02	lasso	5	0.01	5.1e-02	-4.43	-5.4	5.8e-08	0.86	0.02	0.94	FALSE
20	GTEx	Pancreas	MAEA	0.29	0.12	enet	20	0.24	2.3e-10	-3.97	-5.2	2.0e-07	0.65	0.13	0.86	FALSE
21	GTEx	Pituitary	UVSSA	0.43	0.07	lasso	7	0.24	9.3e-07	2.75	5.2	2.4e-07	-0.73	0.10	0.85	FALSE
22	GTEx	Pituitary	CRIPAK	0.39	0.06	enet	29	0.13	4.6e-04	-5.09	5.7	1.4e-08	-0.64	0.08	0.64	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	MAEA	0.16	0.04	lasso	11	0.08	3.8e-05	3.80	-5.6	1.9e-08	0.65	0.03	0.95	FALSE
24	GTEx	Skin Sun Exposed Lower leg	CRIPAK	0.36	0.09	enet	40	0.35	8.7e-30	3.80	5.4	5.6e-08	-0.45	0.99	0.01	FALSE
25	GTEx	Spleen	MAEA	0.39	0.16	lasso	8	0.24	6.8e-07	-4.81	-5.4	5.5e-08	0.64	0.06	0.73	FALSE
26	GTEx	Testis	CTBP1	0.20	0.20	lasso	3	0.19	7.0e-09	-5.15	-5.2	2.1e-07	0.89	0.50	0.50	FALSE
27	GTEx	Thyroid	MAEA	0.30	0.18	enet	34	0.37	6.7e-30	-4.43	-5.5	4.4e-08	0.72	0.19	0.81	FALSE
28	GTEx	Vagina	CRIPAK	0.42	0.04	enet	36	0.29	1.9e-07	0.94	5.7	1.4e-08	-0.47	0.05	0.58	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC100130872	0.07	0.00	blup	44	0.00	1.6e-01	-5.09	5.3	1.2e-07	-0.69	0.01	0.35	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100130872	0.08	0.03	blup	44	0.04	8.9e-05	3.94	6.2	5.1e-10	-0.83	0.00	0.96	TRUE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPON2	0.15	0.10	enet	10	0.11	1.1e-11	4.13	6.0	2.5e-09	-0.55	0.01	0.82	FALSE