TWAS
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Traits
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Traits
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Pulse rate, automated reading
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chr5:86,867,897-88,427,942
Best TWAS P=1.98e-09 · Best GWAS P=1.12e-09 conditioned to 0.0942
86.8M
87M
87.2M
87.4M
87.6M
87.8M
88M
88.2M
88.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Gastroesophageal Junction
TMEM161B-AS1
0.19
0.09
lasso
6
0.09
4.2e-04
5.5
6.0
2.0e-09
0.89
0.08
0.76
TRUE
4
GTEx
Pituitary
TMEM161B-AS1
0.22
0.23
lasso
4
0.24
8.6e-07
4.8
5.6
2.3e-08
0.87
0.12
0.75
FALSE
3
GTEx
Heart Atrial Appendage
TMEM161B-AS1
0.11
0.06
lasso
5
0.05
2.6e-03
5.6
5.3
1.1e-07
0.96
0.05
0.91
FALSE
1
GTEx
Cells Transformed fibroblasts
TMEM161B-AS1
0.13
0.10
enet
12
0.12
5.3e-09
4.6
5.3
1.2e-07
0.89
0.06
0.94
FALSE