Best TWAS P=1.98e-09 · Best GWAS P=1.12e-09 conditioned to 0.0942
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TMEM161B-AS1 | 0.13 | 0.10 | enet | 12 | 0.12 | 5.3e-09 | 4.6 | 5.3 | 1.2e-07 | 0.89 | 0.06 | 0.94 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 5.5 | 6.0 | 2.0e-09 | 0.89 | 0.08 | 0.76 | TRUE |
| 3 | GTEx | Heart Atrial Appendage | TMEM161B-AS1 | 0.11 | 0.06 | lasso | 5 | 0.05 | 2.6e-03 | 5.6 | 5.3 | 1.1e-07 | 0.96 | 0.05 | 0.91 | FALSE |
| 4 | GTEx | Pituitary | TMEM161B-AS1 | 0.22 | 0.23 | lasso | 4 | 0.24 | 8.6e-07 | 4.8 | 5.6 | 2.3e-08 | 0.87 | 0.12 | 0.75 | FALSE |