TWAS
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Models
Genes
Traits
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Traits
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Pulse rate, automated reading
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chr5:122,045,488-123,432,250
Best TWAS P=6.51e-14 · Best GWAS P=1.17e-13 conditioned to 0.323
122M
122.2M
122.4M
122.6M
122.8M
123M
123.2M
123.4M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
CEP120
0.10
0.14
blup
70
0.14
2.6e-14
7.3
-7.5
6.5e-14
-0.95
0.01
0.99
TRUE
2
GTEx
Cells EBV-transformed lymphocytes
KRT8P33
0.16
-0.01
lasso
8
0.01
2.1e-01
-6.5
-5.9
3.5e-09
-0.40
0.08
0.33
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CSNK1G3
0.06
0.04
enet
10
0.05
2.3e-06
-4.8
-5.6
2.6e-08
-0.56
0.01
0.98
FALSE
1
GTEx
Artery Aorta
KRT8P33
0.10
0.04
lasso
6
0.05
9.1e-04
3.1
-5.3
1.3e-07
-0.68
0.04
0.86
FALSE