Best TWAS P=6.51e-14 · Best GWAS P=1.17e-13 conditioned to 0.323
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | 3.1 | -5.3 | 1.3e-07 | -0.68 | 0.04 | 0.86 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | KRT8P33 | 0.16 | -0.01 | lasso | 8 | 0.01 | 2.1e-01 | -6.5 | -5.9 | 3.5e-09 | -0.40 | 0.08 | 0.33 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | 7.3 | -7.5 | 6.5e-14 | -0.95 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | -4.8 | -5.6 | 2.6e-08 | -0.56 | 0.01 | 0.98 | FALSE |