Best TWAS P=6.1e-13 · Best GWAS P=7.55e-13 conditioned to 0.021
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DPY19L2P1 | 0.04 | 0.01 | blup | 22 | 0.02 | 3.8e-03 | -5.96 | 7.2 | 6.1e-13 | 0.81 | 0.01 | 0.92 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DPY19L1 | 0.25 | 0.02 | blup | 62 | 0.05 | 2.6e-06 | 0.57 | -5.3 | 9.5e-08 | -0.42 | 0.25 | 0.39 | FALSE |