Hub : Genes

DPY19L1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0250	1.4e-06	0.049	0.044	0.062	0.046	0.059	1.2e-06	4.4e-06	4.4e-08	2.3e-06	9.5e-08
2	GTEx	Adipose Subcutaneous	0.1380	0.0400	1.7e-05	0.005	NA	0.056	NA	0.065	1.1e-01	NA	2.1e-05	NA	5.4e-06
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1230	0.0450	9.7e-04	0.014	NA	0.027	NA	0.050	5.3e-02	NA	1.2e-02	NA	9.5e-04
4	GTEx	Skin Sun Exposed Lower leg	0.1520	0.0440	8.0e-05	0.071	NA	0.042	NA	0.050	1.6e-06	NA	2.0e-04	NA	5.7e-05
5	GTEx	Whole Blood	0.1060	0.0350	3.4e-04	0.024	NA	0.031	NA	0.039	2.3e-03	NA	6.7e-04	NA	1.6e-04
6	METSIM	Adipose	0.0403	0.0160	1.7e-03	-0.002	0.012	0.003	0.012	-0.001	9.6e-01	5.0e-03	1.0e-01	4.9e-03	4.2e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0625	0.0219	1.6e-04	0.066	0.029	0.040	0.035	0.057	7.6e-09	1.1e-04	6.6e-06	2.3e-05	8.1e-08
8	YFS	Blood	0.1722	0.0307	0.0e+00	0.107	0.127	0.122	0.125	0.120	3.5e-33	3.3e-39	9.6e-38	7.4e-39	4.1e-37
9	TCGA	Lung Squamous Cell Carcinoma	0.0250	0.0149	5.1e-03	0.017	0.024	0.023	NA	0.013	4.8e-03	8.3e-04	9.8e-04	NA	1.0e-02
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.0720	0.0430	3.0e-03	0.023	0.030	0.018	NA	0.018	1.0e-02	3.8e-03	2.0e-02	NA	2.2e-02
11	TCGA	Prostate Adenocarcinoma	0.2454	0.1130	2.0e-05	0.015	0.054	0.049	NA	0.038	8.3e-03	2.6e-06	7.4e-06	NA	7.0e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bipolar Disorder (2018)	2.9	4.5	8.5	-2.2	2.1	2.9	2.5	1.9	1.9	-1.7	2.3	1.9	2.5	0.7
Bipolar Disorder or Schizophrenia	1.4	3.4	10.4	-3.1	0.6	2.2	1.6	1.6	0.6	-3.2	0.3	1.6	1.1	-1.8
Depressed Affect (Nagel 2018)	0.4	0.8	4.1	0.6	-2.0	-0.6	-0.6	-0.6	-0.2	1.2	0.3	-0.4	-0.9	-0.5
Depression (Nagel 2018)	0.4	0.7	3.5	-0.3	-1.9	0.3	-0.2	-1.0	-1.1	0.2	-0.4	-0.5	-0.1	-0.9
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.8	0.6	-0.3	-0.3	-0.9	-0.5	-0.2	-0.0	-1.7	-1.1	-1.0	-0.3
Neuroticism (Nagel 2018)	0.3	0.7	2.9	0.6	-1.7	-1.0	-0.8	0.7	-0.2	0.2	0.5	-0.1	-1.2	0.5
Schizophrenia (2018)	1.1	2.3	8.2	-2.2	-0.9	0.5	-0.0	0.6	-0.8	-2.8	-1.4	0.5	-0.5	-2.9
Schizophrenia vs Biploar Disorder	0.4	0.5	2.2	-0.7	0.6	0.2	0.1	0.7	0.6	-1.5	-0.8	1.1	-0.1	-0.5
Worry (Nagel 2018)	0.5	1.1	3.9	-0.3	-0.1	0.8	0.4	2.0	0.5	-1.2	1.1	1.6	-0.2	1.4
Alzheimer’s Disease (in mother)	1.0	1.2	3.0	-0.1	1.5	0.9	1.0	0.0	1.3	0.4	1.7	-0.1	1.3	1.6
Alzheimer’s Disease (in father)	0.7	0.8	3.1	0.9	0.8	0.3	0.5	1.0	-0.4	0.8	1.0	1.0	0.5	1.8
Alzheimer’s Disease (including proxy)	0.6	0.8	3.9	0.9	0.9	0.3	0.3	0.2	-0.3	1.0	1.4	-0.1	0.7	2.0
Crohns Disease (2017)	1.1	2.5	4.3	-1.6	1.4	1.4	1.8	2.1	1.9	-1.6	1.8	1.7	1.4	-0.1
Irritable Bowel Disease (IBD)	2.2	5.2	9.1	-1.2	1.8	2.0	2.6	2.9	2.8	-1.2	3.0	2.5	2.4	1.8
Ulcerative Colitis (UC)	2.8	5.3	9.7	-0.9	1.7	2.1	2.6	2.8	2.4	-0.8	3.1	2.5	2.6	2.6
Major Depression (MDD)	0.5	0.6	1.5	1.0	1.1	-1.2	-0.7	0.1	0.4	0.7	0.2	-0.6	-0.3	1.1
Reaction Time	2.0	3.8	9.3	2.8	-2.0	-1.7	-1.8	-2.3	-1.2	3.0	-1.0	-1.8	-1.5	1.3
Verbal and Numeric Reasoning (VNR)	0.8	1.9	7.5	-1.3	-0.2	0.0	-1.1	0.1	-0.1	-2.2	-1.9	-0.3	-1.5	-2.7
Breast Cancer	0.4	1.0	2.3	0.0	0.2	-1.3	-1.5	-0.4	-1.5	-1.0	-0.3	-0.4	-1.3	-1.4
Ovarian Cancer	1.7	2.3	4.5	0.6	-1.4	-1.9	-1.8	-1.5	-2.1	0.1	-1.5	-1.2	-1.5	-1.8
Prostate Cancer	0.3	0.4	1.5	0.4	-0.1	-0.4	0.6	-0.4	-0.5	1.2	0.8	-0.7	1.0	0.2
Age at First Birth	0.4	0.6	1.9	-1.1	0.5	1.1	0.6	0.9	-0.2	-1.4	0.2	0.4	0.6	-0.6
Bipolar Disorder (2011)	1.9	1.9	4.7	-1.5	2.2	1.0	1.3	1.5	1.0	-1.2	1.6	1.4	1.1	-0.3
Body Mass Index (BMI) (2010)	0.6	0.8	4.1	-0.2	-1.0	-0.7	-0.5	-1.2	-2.0	-0.1	-0.1	-0.0	-0.7	-0.9
Coronary Artery Disease (CAD)	2.6	3.1	5.5	-1.2	2.4	1.8	2.0	2.2	2.2	-0.9	1.8	1.7	1.8	0.9
Crohns Disease (2012)	0.6	0.9	2.0	-0.5	0.3	1.4	1.4	0.6	0.9	-0.1	1.4	0.8	1.1	0.5
Mean Putamen Volume	0.2	0.3	1.4	0.4	0.5	-0.4	-0.1	-1.2	-0.5	0.8	-0.0	-0.3	0.1	0.2
Fasting Glucose	0.9	1.0	3.6	0.6	0.0	0.2	0.1	0.7	1.1	0.6	1.8	1.4	-0.3	1.9
HbA1C	0.3	0.3	1.0	-0.3	0.1	-0.4	-0.6	0.4	-0.3	-0.7	-1.0	-0.9	-0.2	-0.4
HDL Cholesterol	0.9	1.5	7.8	1.6	1.7	-0.4	0.1	0.9	0.9	1.0	0.5	-0.0	0.1	2.8
LDL Cholesterol	0.3	0.4	1.3	-0.4	-1.0	0.7	0.3	-1.1	0.3	0.1	-0.5	-0.0	0.2	-1.1
Lupus	2.7	4.1	6.1	-1.8	1.7	2.5	2.3	2.5	1.6	-1.5	2.4	2.1	2.4	0.6
Neuroticism (2016)	0.7	1.1	2.5	1.0	-1.6	-1.3	-1.5	-0.8	-1.1	0.7	0.2	-0.6	-1.2	-0.0
Primary Biliary Cirrhosis	1.9	2.7	5.2	-0.8	1.6	0.8	2.1	2.3	1.0	-0.6	2.2	1.5	2.2	1.6
Rheumatoid Arthritis	0.2	0.3	0.5	-0.6	-0.5	0.6	0.7	0.1	-0.6	-0.1	-0.3	0.7	0.6	-0.4
Schizophrenia (2014)	1.2	2.7	9.5	-2.4	-0.6	1.0	0.2	0.4	-1.1	-3.1	-1.0	1.3	-0.3	-2.9
Triglycerides	0.3	0.5	1.5	0.0	-0.6	-1.1	-1.0	-0.0	-0.4	-0.8	-0.3	-0.4	-1.2	-0.5
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.7	0.3	-0.5	-0.5	-0.3	-1.2	-1.0	1.0	0.2	-1.3	-0.5	-1.0
Ulcerative Colitis	2.4	3.5	9.3	-0.2	1.3	1.5	2.0	1.9	1.9	0.0	3.0	2.1	1.9	2.5
Blood Eosinophil Count	0.2	1.5	3.5	1.0	-1.9	-1.0	-1.1	-1.9	-1.2	1.4	-0.9	-0.7	-1.1	-0.6
Blood Platelet Count	0.8	9.0	20.5	-2.9	0.1	4.5	4.2	1.7	2.5	-1.0	3.9	3.3	3.9	0.8
Blood Red Count	0.1	1.0	2.0	-1.4	0.1	1.2	1.0	0.6	0.7	-1.4	0.8	1.2	0.8	-1.1
Blood White Count	0.1	0.4	1.8	0.1	0.5	-0.2	-0.3	0.2	1.3	-0.2	-0.6	1.1	-0.6	-0.2
Heel T-Score	0.1	1.0	2.9	-0.4	0.5	1.3	1.3	0.7	0.4	-0.2	1.0	0.8	1.4	1.7
BMI	2.6	15.1	23.9	4.2	-2.3	-4.8	-4.8	-4.1	-2.6	3.4	-3.8	-4.9	-4.7	-0.4
Height	1.7	33.4	54.3	-6.9	4.5	6.7	6.8	6.3	4.2	-6.1	5.1	7.4	5.7	0.3
Waist Hip Ratio (WHR)	0.5	2.1	6.0	-2.5	0.9	1.4	1.7	0.8	0.2	-1.9	1.3	0.8	1.9	-1.0
Systolic Blood Pressure	0.7	3.4	10.0	-2.5	0.3	1.6	0.5	1.3	1.2	-3.2	-0.8	2.9	-0.2	-2.4
Smoking Status	0.1	0.3	1.5	-0.8	-0.7	1.2	0.2	-0.3	0.5	-0.7	-0.0	0.3	0.2	-0.5
Allergy or Eczema	0.8	2.0	4.7	0.9	-0.9	-1.1	-2.0	-1.1	-1.5	-0.2	-2.2	-2.1	-1.6	-0.8
Cardiovascular Disease	0.7	2.3	9.6	-2.3	1.0	1.1	0.5	1.7	1.5	-3.1	0.0	1.4	-0.1	-1.0
Hypothyroidism (self reported)	0.9	2.1	5.5	1.6	-1.6	-1.5	-1.2	-1.6	-2.3	1.4	-0.8	-1.0	-1.4	0.9
Respiratory disease	0.4	0.9	3.0	-1.1	1.6	0.8	0.5	0.7	1.7	-1.2	0.4	0.5	0.3	0.1
Type 2 Diabetes (T2D) (2018)	0.8	1.4	3.1	-0.9	1.4	1.0	1.1	1.4	0.2	-1.0	1.8	1.3	1.3	1.0
Lung FEV1/FVC ratio	0.2	0.8	3.8	0.0	-1.9	0.2	0.1	-1.9	-0.6	0.9	0.0	-0.6	0.3	-0.2
Lung FVC	0.1	0.6	1.9	0.2	-1.4	0.7	0.1	-1.1	-0.9	0.9	1.1	-0.3	0.2	-0.4
Neuroticism	0.3	0.6	1.7	0.4	-1.3	-0.3	-0.4	0.7	-0.8	-0.2	1.0	0.8	-1.0	1.0
Chronotype (morning person)	0.5	1.1	2.9	0.3	0.2	1.0	1.3	0.2	-0.0	1.0	1.5	1.0	1.4	1.7
Hair Pigment	0.0	1.1	3.6	1.3	0.0	-1.1	-1.3	-0.5	1.1	0.8	-0.3	-1.9	-1.1	0.3
Tanning	0.1	1.3	4.2	1.0	-0.0	-0.2	0.7	0.5	0.9	1.4	1.8	1.4	0.4	2.1
Hand grip strength (left)	2.1	5.7	10.3	-2.0	3.1	2.8	2.2	3.2	2.4	-2.6	1.7	2.6	1.8	0.8
Number of treatments/medications taken	0.3	0.6	2.2	-0.0	0.3	-1.5	-0.9	0.5	-0.3	-0.7	-0.4	-1.2	-0.8	0.1
Average weekly spirits intake	0.6	0.8	2.0	-1.4	0.6	1.2	0.7	0.9	-0.1	-1.3	0.0	0.5	0.9	-0.8
Sensitivity / hurt feelings	0.6	1.1	2.2	0.6	-1.5	-1.3	-1.2	-0.8	-0.9	0.5	-0.6	-1.4	-1.1	-0.8
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.5	0.7	-1.3	-0.7	-1.2	-1.2	-1.6	0.7	-0.6	-1.3	-1.2	-0.4
Hearing difficulty/problems: Yes	0.3	0.5	2.9	0.6	0.5	0.3	0.2	-0.6	0.0	0.7	0.9	0.2	0.1	1.7
Relative age of first facial hair	0.5	0.9	2.7	-1.6	1.6	0.7	0.9	0.4	0.1	-1.6	-0.1	0.8	0.6	-0.1
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	5.5	1.2	-1.2	-0.6	-0.1	-0.9	-0.4	1.6	0.8	-1.4	0.3	2.4
Ever used hormone-replacement therapy (HRT)	4.6	5.9	11.6	3.0	-1.6	-3.4	-3.1	-2.2	-2.1	2.4	-1.6	-2.7	-2.5	0.4
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.5	-0.4	-0.7	-0.4	0.2	-0.8	-0.0	0.3	-0.1	-0.5	0.2
Systolic blood pressure, automated reading	0.4	1.1	2.7	-0.5	-1.2	-0.3	-1.0	-0.5	0.7	-1.0	-1.6	0.8	-1.4	-1.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.9	-0.6	-0.4	-0.2	-0.4	0.1	-0.6	-0.8	-0.6	0.0	-0.4	-1.0
Angina	1.2	1.5	3.9	-2.0	0.5	1.8	1.7	0.5	1.1	-1.2	0.8	1.4	1.1	0.4
Medication for hormone replacement therapy	0.2	0.2	0.5	0.7	0.1	-0.7	-0.3	-0.3	0.5	0.6	0.4	-0.5	-0.1	0.4
Vitamin and mineral supplements	1.2	1.6	3.9	-0.9	0.7	1.7	1.2	2.0	0.9	-1.4	1.1	1.6	1.2	0.7
Supplements: Zinc	1.7	1.9	5.0	0.4	-0.9	-0.9	-0.7	-1.6	-1.7	1.1	-2.0	-1.6	-0.2	-2.2
Medication: Co-codamol	1.4	1.6	4.0	-1.3	2.0	0.9	0.9	1.3	1.5	-1.4	1.5	1.3	0.6	0.6
Medication: Metformin	0.5	0.7	2.2	-1.0	-0.1	0.8	0.5	0.5	-0.7	-1.1	1.2	1.5	-0.1	-0.4
Diabetes (father)	4.2	5.2	11.4	2.3	-2.5	-1.8	-2.5	-2.5	-3.4	1.9	-2.2	-2.1	-2.3	0.0
Diabetes (mother)	1.0	1.2	4.5	0.8	-2.1	-1.0	-1.0	-0.9	-1.9	0.4	-0.6	0.1	-1.2	0.0
Severe depression (siblings)	0.2	0.2	0.8	0.4	-0.4	-0.7	-0.4	-0.5	-0.5	0.3	0.2	-0.9	-0.1	0.0
Pack years adult smoking proportion	0.7	1.0	3.8	-1.0	0.7	-0.1	-0.9	0.1	-1.1	-1.9	-1.1	-0.3	-1.0	-1.2
Impedance of leg (right)	3.2	15.5	20.9	-4.3	2.8	4.4	4.6	4.4	3.9	-4.0	3.6	4.5	4.3	0.4
Leg fat-free mass (left)	0.3	1.4	3.1	1.1	-0.4	-1.3	-1.5	-1.1	-1.1	0.6	-1.6	-1.4	-1.8	0.1
Trunk fat percentage	0.1	0.4	1.2	-0.9	0.6	-0.2	-0.3	0.1	0.5	-1.1	-0.6	-0.7	-0.5	-0.9
Hand grip strength (right)	2.6	6.9	13.8	-2.3	3.2	2.5	2.3	3.7	3.1	-2.9	1.9	3.3	1.9	0.5
Townsend deprivation index at recruitment	0.2	0.3	1.8	-0.7	-1.3	0.3	0.1	-0.4	-0.0	-0.3	0.0	-0.0	-0.3	-0.6
Current tobacco smoking	1.0	1.6	4.6	-1.4	-0.0	2.1	1.6	1.0	-0.0	-1.0	1.0	1.5	1.8	0.4
Average weekly fortified wine intake	3.8	4.5	9.3	-2.9	1.8	1.9	1.8	2.5	1.2	-3.0	1.7	2.6	1.7	-1.4
Maternal smoking around birth	1.0	1.5	5.2	1.0	1.1	0.2	0.2	1.8	0.7	0.8	1.5	1.3	0.4	2.3
Fed-up feelings	0.5	0.8	2.7	0.6	-1.7	-0.9	-1.1	-0.4	-0.4	0.4	-0.1	-0.2	-1.7	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.9	-1.0	-1.4	1.3	0.4	-0.6	-0.6	-0.5	-0.3	0.7	0.1	-0.9
Relative age voice broke	0.9	1.4	3.7	-1.2	1.6	0.1	0.6	1.6	1.1	-1.9	0.5	1.6	0.0	0.4
Taking other prescription medications	0.4	0.6	1.7	-0.0	0.8	-0.2	0.3	0.8	1.2	0.1	1.3	-0.2	0.6	1.3
Age when periods started (menarche)	1.0	2.4	7.0	2.0	-1.3	-2.6	-2.0	-1.5	-0.4	1.4	-0.8	-1.2	-1.9	-0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	0.4	-1.0	-0.7	-0.5	-0.6	-0.3	0.1	0.5	0.1	-1.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	4.5	0.7	-1.5	-0.4	0.4	-0.1	-0.2	0.9	0.8	0.1	0.4	2.1
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.9	0.8	0.7	0.6	1.0	1.4	0.3	0.9	2.2	0.8	1.1	2.2
Qualifications: CSEs or equivalent	0.3	0.4	1.7	0.9	0.1	-1.3	-0.4	-0.3	-0.6	1.0	-0.5	-0.3	0.1	0.6
Serious illness, injury or assault to yourself	0.5	0.6	1.5	-0.3	0.3	-0.8	0.6	1.2	1.2	0.1	1.0	-0.4	0.9	0.9
High blood pressure	0.4	1.1	6.2	-1.8	0.2	0.4	-0.6	0.0	0.3	-2.5	-0.8	-0.2	-0.8	-1.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.7	0.7	-0.5	-0.9	-1.1	-0.7	-0.6	0.1	-1.1	-1.6	-0.6	-0.2
Multivitamins +/- minerals	1.0	1.3	2.6	1.3	-0.6	-1.6	-1.1	-1.3	-1.1	1.4	-0.6	-1.5	-1.0	0.1
Stomach or abdominal pain in last month	0.8	1.0	2.8	0.7	-1.7	-0.3	0.4	-0.1	-1.5	1.5	1.3	-0.4	0.7	0.5
Supplements: Glucosamine	2.0	2.6	4.0	1.8	-1.3	-2.0	-1.8	-2.0	-1.2	1.7	-1.3	-1.9	-1.8	-0.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.4	0.1	0.2	0.2	0.5	0.3	-0.8	0.3	1.5	0.2	0.5	1.1
Medication: Atenolol	3.4	4.2	13.9	-3.6	2.1	1.4	1.8	1.4	1.1	-3.7	0.9	1.6	1.2	-1.4
Medication: Levothyroxine sodium	1.5	2.5	5.2	1.0	-1.3	-1.8	-2.1	-1.9	-2.3	0.3	-1.6	-1.0	-2.2	-0.7
Sitting height	0.7	5.1	10.2	-2.1	1.3	3.1	2.8	2.6	1.9	-1.8	2.0	3.2	1.9	0.8
Chronic bronchitis/emphysema (father)	0.2	0.3	0.9	0.3	0.3	-0.2	0.3	-0.7	0.4	0.5	1.0	-0.1	0.1	0.9
High blood pressure (mother)	1.4	2.0	7.0	-1.5	0.3	1.2	0.8	2.0	0.9	-2.7	1.6	1.7	0.4	0.5
Body mass index (BMI)	2.3	9.7	16.5	3.0	-2.0	-3.8	-4.1	-3.2	-2.4	2.3	-3.5	-3.8	-3.9	-0.5
Impedance of leg (left)	3.2	15.6	22.8	-4.1	3.1	4.2	4.5	4.8	4.0	-4.1	3.7	4.5	4.2	0.7
Leg predicted mass (left)	0.3	1.3	2.9	1.1	-0.3	-1.3	-1.5	-1.1	-1.1	0.6	-1.6	-1.3	-1.7	0.1
Trunk fat mass	0.1	0.4	0.9	-0.4	0.4	-0.6	-0.7	-0.1	0.2	-0.8	-0.8	-0.8	-1.0	-0.6
Waist circumference	0.9	3.4	6.1	0.7	-1.1	-2.4	-2.5	-1.8	-1.4	0.2	-2.2	-2.4	-2.5	-1.2
Number of incorrect matches in round	0.3	0.4	1.1	0.8	0.9	-0.7	-0.6	0.1	0.7	0.5	-0.4	-1.0	-0.5	-0.5
Past tobacco smoking	1.1	2.0	4.5	-0.6	1.1	1.0	2.1	1.6	0.1	-0.1	1.9	1.7	2.1	1.3
Alcohol usually taken with meals	1.9	3.1	5.1	-2.1	2.0	1.6	1.8	2.2	0.6	-2.2	1.6	1.9	1.7	0.0
Nervous feelings	0.5	1.0	2.4	-1.1	-1.5	0.6	0.1	1.1	-0.8	-1.6	0.3	1.4	-0.5	-0.6
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	6.4	2.0	-1.3	-1.5	-2.0	-1.5	-2.5	1.3	-0.9	-1.7	-1.7	0.2
Hearing difficulty/problems with background noise	0.4	0.7	2.4	0.0	0.7	1.0	0.9	-0.0	-0.2	0.3	0.9	0.9	0.8	1.5
Hair/balding pattern: Pattern 2	0.5	0.7	2.3	-0.8	-0.0	1.1	0.9	-0.3	1.5	0.0	0.3	0.4	0.8	-1.3
Had menopause	3.4	4.3	8.5	1.9	-1.1	-2.9	-2.7	-1.8	-1.7	1.5	-2.2	-2.2	-2.5	-1.3
Had other major operations	0.3	0.3	1.1	0.2	-0.3	-1.0	-0.6	0.2	0.2	-0.3	0.7	-1.0	-0.7	-0.2
Forced vital capacity (FVC)	1.4	5.3	10.8	-2.1	0.6	3.3	3.0	2.2	1.0	-1.6	3.3	2.9	2.5	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	9.4	1.2	-0.2	-0.5	0.3	0.0	0.3	1.2	1.4	-0.1	0.3	3.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	0.7	0.2	-0.1	0.3	-0.2	0.3	0.9	0.4	-0.9	0.6	0.7
Qualifications: None of the above	0.1	0.2	0.3	0.5	-0.4	-0.6	-0.5	-0.4	0.3	0.4	0.5	0.4	-0.6	0.3
Financial difficulties in last 2 years	0.3	0.4	1.3	0.6	0.0	0.3	0.1	-0.7	-0.1	1.1	0.8	-0.9	0.4	1.0
Mouth/teeth dental problems	0.4	0.6	1.6	0.9	0.1	-1.2	-0.8	-1.0	-0.5	0.9	-0.2	-0.9	-0.7	-0.9
Heart attack	1.8	2.3	5.4	-2.3	1.6	1.6	1.8	1.3	1.2	-1.7	0.6	1.2	1.4	-1.0
Allergy	0.2	0.4	1.3	0.5	-0.8	-0.1	-0.2	-0.8	-1.1	0.9	-0.4	0.1	-0.3	-0.4
Pain all over the body in last month	1.9	2.0	4.8	1.2	-1.6	-1.0	-1.5	-2.2	-1.6	1.2	-1.1	-1.6	-1.5	-0.2
Diabetes (self-reported)	0.6	1.0	2.0	-1.2	0.6	0.9	0.9	0.9	0.2	-1.4	1.4	1.4	0.8	-0.0
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	4.4	0.7	-1.8	-0.5	-0.6	-1.9	-2.1	1.2	-1.4	-0.8	-0.2	-0.1
Medication: Ramipril	0.6	0.7	3.1	-1.1	1.1	0.4	-0.1	0.8	-0.2	-1.8	-0.8	1.0	-0.5	-0.1
Medication: Simvastatin	0.1	0.2	0.4	-0.1	0.6	-0.6	-0.6	-0.2	0.2	-0.2	0.2	-0.6	-0.6	0.4
Fluid intelligence score	0.4	0.9	3.2	-1.3	-0.5	0.7	-0.3	0.3	0.0	-1.8	-1.4	0.1	-0.6	-1.4
Illnesses of siblings	0.6	0.8	2.0	0.2	0.5	1.0	1.0	0.6	1.4	0.5	1.0	1.0	0.9	1.1
Neuroticism score	0.3	0.6	1.7	0.6	-1.3	-0.8	-0.8	0.4	-1.0	0.0	0.5	0.2	-1.2	0.4
Weight	0.4	1.7	4.8	0.8	-0.4	-1.6	-1.9	-1.0	-0.9	0.2	-1.8	-1.4	-2.2	-0.4
Impedance of arm (right)	4.2	19.4	30.7	-5.5	3.3	5.5	5.5	4.3	3.7	-4.6	3.9	4.3	5.0	-0.4
Arm fat percentage (right)	0.4	1.5	4.0	0.8	-0.4	-1.4	-1.5	-1.4	-0.9	0.7	-1.5	-2.0	-1.5	-0.3
Trunk fat-free mass	0.1	0.6	1.6	1.0	0.1	-0.7	-1.1	-0.5	-0.7	0.6	-0.8	-0.3	-1.3	1.0
Hip circumference	0.4	1.9	6.0	0.4	-0.7	-1.6	-2.0	-1.1	-0.8	-0.3	-1.9	-1.4	-2.5	-0.9
Time employed in main current job	1.8	2.1	4.8	1.5	-2.2	-2.2	-1.8	-0.3	-1.9	0.9	-1.0	-1.1	-1.4	0.0
Alcohol intake versus 10 years previously	4.3	6.4	14.8	3.6	-3.4	-2.6	-1.7	-1.9	-2.1	3.9	-0.7	-2.5	-1.0	2.4
Father’s age at death	0.6	0.8	2.4	0.4	-0.3	0.4	0.8	-0.6	0.9	1.6	0.7	-0.6	1.1	1.4
Worrier / anxious feelings	0.2	0.4	1.0	0.5	-0.5	-0.3	-0.4	1.0	0.3	-0.5	0.8	0.2	-0.9	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.2	0.4	-1.3	-0.9	-0.6	-1.4	-1.1	0.9	-0.5	-1.5	-0.8	-0.5
Falls in the last year	0.1	0.1	0.5	-0.6	-0.3	0.4	0.2	0.1	0.7	-0.5	-0.2	-0.1	-0.0	-0.3
Hair/balding pattern: Pattern 3	1.8	2.7	6.4	2.3	-1.9	-1.3	-1.5	-1.9	-1.6	2.5	-0.6	-1.9	-0.9	0.3
Number of live births	2.0	2.8	5.0	1.7	-1.6	-2.0	-1.6	-2.1	-0.8	2.2	-1.5	-2.2	-1.4	-0.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	9.1	-1.6	0.4	2.8	2.6	1.5	0.6	-1.0	3.0	2.3	2.4	0.9
Pulse rate	1.7	2.9	10.5	-2.7	-0.6	3.2	1.5	-0.7	0.2	-1.7	-0.1	1.6	1.2	-2.0
Happiness	0.3	0.4	1.4	-0.8	0.0	0.4	-0.1	0.2	0.5	-0.9	-0.8	-0.5	-0.1	-1.2
Noisy workplace	0.4	0.5	1.4	0.1	0.7	0.3	0.8	0.2	0.8	0.3	1.1	0.2	1.2	1.1
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.6	-1.6	0.4	1.9	1.2	0.5	0.2	-1.7	0.8	0.2	1.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	4.5	0.9	-1.0	0.4	-0.1	-0.5	-0.4	1.2	0.2	-0.2	-0.1	2.1
Mouth/teeth dental problems: Dentures	0.3	0.4	1.5	-0.9	-0.1	0.8	0.9	0.3	0.4	-0.6	-0.2	1.2	0.6	0.1
Asthma	0.7	1.4	3.6	-1.4	1.4	1.1	0.6	1.2	1.9	-1.7	0.9	1.0	0.4	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.3	-0.2	-0.4	-0.3	0.1	-0.9	-0.3	0.4	0.1	-1.2	0.5	-0.5
Medication: Cholesterol lowering	0.4	0.7	2.2	-1.0	1.1	0.2	0.6	1.5	0.2	-1.4	0.5	0.6	0.4	0.3
Depression (self-reported)	0.9	1.0	2.1	-1.1	1.4	0.6	0.9	1.2	0.8	-1.2	0.9	0.7	1.3	0.5
Medication: Lansoprazole	9.1	10.4	17.6	-4.2	2.5	2.8	3.9	3.1	2.4	-3.4	3.1	4.0	3.9	-0.5
Prospective memory result	1.2	1.4	5.4	1.2	-2.3	-1.1	-1.1	-0.9	0.5	1.1	0.2	-0.9	-1.8	0.0
Lung cancer (father)	1.5	1.7	3.1	1.2	-1.3	-1.6	-1.2	-1.6	-1.8	1.2	-1.0	-1.5	-1.1	-0.6
Illnesses of mother	0.3	0.4	1.9	1.0	0.0	-0.6	-0.2	-0.7	-0.1	1.4	-0.5	-0.8	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	9.4	-2.1	0.6	3.1	2.4	1.6	1.0	-1.7	2.1	2.5	1.9	0.0
Pulse wave Arterial Stiffness index	0.7	0.8	2.9	0.6	-1.7	-0.4	-0.5	-1.6	0.0	1.1	-0.5	-0.0	-1.0	-0.5
Impedance of arm (left)	4.9	22.8	34.8	-5.9	3.8	5.7	5.8	4.9	3.9	-5.2	4.3	4.9	5.2	-0.8
Arm fat mass (right)	0.7	2.9	5.5	1.2	-0.8	-1.9	-2.2	-1.8	-1.5	0.8	-2.1	-2.1	-2.4	-0.5
Trunk predicted mass	0.1	0.8	2.0	1.1	-0.1	-0.8	-1.2	-0.6	-0.8	0.6	-0.9	-0.5	-1.4	0.9
Standing height	1.5	14.9	22.0	-4.5	3.5	4.5	4.3	4.5	3.2	-4.4	3.2	4.7	3.4	0.3
Length of working week for main job	0.4	0.5	1.0	1.0	0.5	-0.5	-1.0	0.1	0.5	0.4	-0.8	-0.7	-0.9	0.6
Exposure to tobacco smoke at home	0.6	0.7	1.9	1.4	0.9	-0.4	-0.7	-0.1	1.0	0.9	-0.2	0.2	-1.2	1.1
Breastfed as a baby	0.3	0.3	1.0	0.4	0.4	-0.8	-0.6	0.3	0.3	0.2	-0.9	0.1	-1.0	-0.5
Tense / ‘highly strung’	0.5	0.8	2.3	-0.1	-0.2	-0.8	-1.1	0.8	-1.5	-1.4	-0.2	0.3	-1.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.6	0.3	-1.1	-0.5	-0.9	-1.3	-1.6	-0.1	-0.5	-1.3	-0.7	0.0
Hair/balding pattern: Pattern 4	4.0	9.7	15.2	-3.9	2.5	3.2	3.1	3.9	3.1	-3.9	2.4	3.6	2.6	-0.1
Birth weight of first child	1.1	2.0	5.6	-1.6	0.9	2.4	2.1	0.7	1.0	-0.7	0.9	1.2	1.9	-0.3
Peak expiratory flow (PEF)	0.2	0.4	2.8	0.2	0.1	0.6	0.2	0.6	-0.4	-0.0	0.3	0.5	0.4	1.7
Pulse wave reflection index	1.4	1.7	4.9	1.8	-1.2	-1.6	-1.1	-1.6	-0.3	2.2	-0.3	-1.1	-1.2	0.2
Ever highly irritable/argumentative for 2 days	0.7	0.9	3.3	1.2	-0.8	-0.8	-0.4	-0.3	0.2	1.1	0.8	-1.2	-0.1	1.8
Loud music exposure frequency	1.5	1.7	7.6	2.3	0.3	-1.0	-1.0	-0.3	-0.5	1.6	-0.0	-0.6	-0.7	2.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.5	-0.0	0.4	0.6	0.9	-0.3	0.3	0.6	-0.0	-0.9	1.2	0.8
Mouth/teeth dental problems: Bleeding gums	3.9	5.1	6.4	-2.4	2.1	2.5	2.5	2.5	2.5	-2.1	1.9	2.5	2.4	0.4
Blood clot in the leg (DVT)	2.0	2.5	4.7	-1.5	1.6	1.8	2.2	1.4	0.9	-1.1	1.9	1.6	2.0	0.9
Medication: Paracetamol	3.4	5.7	13.7	1.9	-2.9	-2.7	-2.7	-2.3	-1.8	1.6	-2.2	-3.7	-2.3	-1.2
Headache pain in last month	0.2	0.4	1.3	-0.4	-0.1	0.2	0.8	0.9	0.7	-0.5	1.1	-0.1	0.8	0.3
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	4.8	1.7	-1.7	-0.4	-0.7	-1.4	-0.3	2.2	-0.8	-0.8	-0.5	-0.1
Glaucoma (self-reported)	0.8	0.9	5.1	-0.0	2.0	0.1	0.3	0.9	2.3	-0.4	0.2	-0.3	0.3	0.4
Gout (self-reported)	0.4	0.6	1.8	1.2	0.1	-0.1	-0.5	-0.6	0.8	1.3	-0.6	-0.6	-0.7	0.7
Hypothyroidism/myxoedema (self-reported)	1.7	3.2	7.5	1.6	-1.9	-2.2	-2.1	-1.7	-2.7	0.9	-1.4	-1.3	-2.2	-0.0
Medication: Amlodipine	0.4	0.6	3.2	-1.1	-0.1	-0.1	-0.2	1.1	-0.3	-1.8	0.1	0.4	-0.5	-0.4
Medication: Ventolin 100micrograms inhaler	1.5	2.0	7.0	-0.2	1.6	1.1	0.9	2.6	1.8	-0.7	1.2	1.2	0.9	1.6
Birth weight	2.2	4.7	11.6	-3.4	1.3	3.2	2.3	1.5	0.9	-2.6	0.0	2.3	2.0	-1.8
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.3	1.3	0.5	-0.6	-0.7	-0.9	-0.5	1.5	0.1	-0.6	-0.4	1.3
High blood pressure (siblings)	1.1	1.5	3.4	0.4	-1.8	-0.9	-1.4	-1.3	-1.5	0.2	-1.5	-1.6	-1.3	-0.6
Forced vital capacity (FVC), Best measure	1.5	5.5	12.1	-2.6	1.1	3.5	2.9	2.2	1.2	-2.3	2.5	3.0	2.2	-0.2
Body fat percentage	0.1	0.5	1.6	0.1	0.2	-0.9	-1.0	-0.3	0.1	-0.3	-1.0	-1.3	-1.0	-0.4
Leg fat percentage (right)	0.5	1.6	3.3	1.1	-0.5	-1.8	-1.8	-1.0	-0.2	0.6	-1.6	-1.8	-1.7	0.1
Arm fat-free mass (right)	0.5	2.5	5.5	1.9	-0.5	-2.0	-2.3	-1.1	-1.1	1.1	-1.6	-1.4	-2.4	0.5
Exposure to tobacco smoke outside home	0.8	1.1	3.6	0.9	-0.8	-0.9	-1.4	-0.7	1.4	0.8	-0.9	-0.1	-1.9	-0.9
Comparative body size at age 10	0.0	0.1	0.5	0.7	-0.2	-0.1	-0.4	-0.1	0.2	0.7	-0.3	0.1	-0.3	0.2
Number of full brothers	0.5	0.7	3.0	0.5	1.3	0.3	0.4	1.1	0.4	0.2	0.7	0.7	-0.0	1.7
Worry too long after embarrassment	0.8	1.4	3.7	1.2	-0.2	-1.9	-1.6	0.1	-1.9	0.1	-0.1	-0.7	-1.6	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.4	0.5	-0.7	-1.5	-1.2	-1.0	-1.9	-0.1	-0.7	-1.2	-0.6	-0.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.3	0.3	0.4	-1.0	-0.6	-0.1	0.4	-0.2	-0.5	-1.1	-0.4	0.6
Number of children fathered	0.8	1.0	2.4	0.2	0.4	0.6	1.2	-0.2	1.3	1.1	1.6	-0.6	1.5	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.4	-1.1	1.6	1.3	1.0	-0.0	0.9	-0.5	-0.2	0.5	0.7	-0.9
Age at first live birth	0.5	0.9	3.4	-0.2	-1.0	0.0	-0.9	-1.1	-1.3	-0.1	-0.1	-0.9	-0.7	-1.8
Pulse wave peak to peak time	1.1	1.3	3.6	-1.0	1.9	0.7	0.8	1.9	0.3	-1.5	0.8	0.4	1.3	0.6
Health satisfaction	0.2	0.3	1.0	0.4	-0.4	-0.6	-0.4	-0.4	0.3	0.5	-0.5	-1.0	-0.4	0.5
Shortness of breath walking on level ground	0.4	0.4	1.6	-1.0	-0.6	-0.2	-0.3	0.2	-0.5	-1.2	-0.5	-0.1	-0.5	-1.1
Qualifications: College or University degree	0.3	0.9	4.5	-0.9	-0.4	0.7	-0.1	-0.7	-0.8	-0.8	-0.4	-1.3	0.1	-2.1
Eye problems/disorders: None of the above	1.8	2.0	4.0	1.6	-1.2	-1.0	-1.2	-1.9	-2.0	2.0	-1.2	-1.5	-1.0	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.4	2.3	-0.2	0.6	1.5	0.5	0.1	0.9	0.1	0.0	0.3	0.3	0.9
Emphysema/chronic bronchitis	0.8	0.9	2.0	-1.0	0.7	0.6	1.0	1.1	0.7	-1.1	1.4	1.0	0.5	1.2
Medication for pain relief, constipation, heartburn	1.1	1.9	5.2	-0.9	1.4	2.1	1.5	0.9	1.1	-0.8	1.4	2.3	1.3	0.4
Neck or shoulder pain in last month	1.0	1.4	4.9	-0.3	1.5	0.0	0.9	1.3	1.8	-0.1	2.2	0.2	1.2	0.8
Medication: Blood pressure	0.3	0.6	2.5	-1.4	1.1	0.3	0.0	-0.1	-0.2	-1.6	-0.4	-0.2	0.0	-0.6
Angina (self-reported)	1.1	1.4	4.0	-2.0	0.4	1.6	1.7	0.5	0.9	-1.2	0.7	1.2	1.1	0.3
Migraine (self-reported)	0.4	0.5	1.9	-0.5	0.5	0.3	0.9	0.3	1.4	-0.2	0.5	-0.2	1.0	0.7
Medication: Ibuprofen	0.4	0.4	2.2	0.3	-0.6	-0.7	-0.1	-0.7	-0.6	0.7	-0.1	-1.5	0.2	-0.6
Medication: Allopurinol	0.5	0.6	1.5	0.9	-0.2	0.0	-0.6	-1.1	0.6	1.2	-0.9	-0.9	-0.5	-0.6
Medication: Omeprazole	0.7	0.9	2.5	1.0	0.9	-1.6	-0.8	1.1	0.8	0.3	-0.0	-0.9	-0.6	1.2
Medication: Seretide 50 evohaler	0.7	0.8	2.3	-1.1	0.6	1.3	1.0	1.5	0.1	-1.0	-0.1	1.1	0.7	-0.2
Mean time to correctly identify matches	1.9	3.6	8.0	2.6	-2.1	-2.0	-2.0	-2.2	-1.3	2.8	-0.9	-1.6	-1.6	0.6
Heart disease (mother)	0.8	1.0	3.4	-1.9	-1.0	1.3	1.2	0.0	-0.5	-1.0	0.6	0.9	0.9	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	5.4	-0.4	2.3	-0.4	-0.5	0.6	0.6	-1.4	-0.8	0.6	-0.5	0.3
Whole body fat mass	0.3	1.4	3.2	0.8	-0.3	-1.6	-1.6	-0.8	-0.6	0.3	-1.6	-1.6	-1.8	-0.2
Leg fat mass (right)	0.7	2.7	5.1	1.6	-0.7	-2.3	-2.3	-1.4	-0.6	0.9	-2.0	-2.0	-2.2	0.1
Arm predicted mass (right)	0.4	2.0	5.0	1.6	-0.6	-1.8	-2.1	-0.8	-1.1	0.7	-1.6	-1.2	-2.2	0.3
Pulse rate, automated reading	2.9	9.3	28.5	-5.0	-1.0	4.6	2.1	-1.4	-1.2	-3.2	-0.1	2.2	1.6	-5.3
Alcohol intake frequency.	1.1	2.6	4.5	1.5	-2.1	-1.9	-1.7	-1.8	-0.8	1.6	-1.3	-1.9	-1.7	-0.3
Comparative height size at age 10	1.5	8.2	12.1	-2.5	2.3	3.0	3.5	3.2	3.3	-1.9	3.1	2.9	3.4	1.6
Number of full sisters	1.5	1.9	6.9	0.4	-1.0	-0.5	-0.8	-2.6	-2.2	1.2	-1.6	-1.3	-0.6	-0.9
Suffer from ‘nerves’	0.7	1.1	2.3	1.2	-1.2	-1.5	-1.1	0.4	-1.1	0.4	0.8	0.0	-1.4	1.3
Overall health rating	0.2	0.4	1.4	0.1	-1.2	-0.8	-0.6	-0.4	0.3	0.4	-0.2	-1.2	-0.6	0.1
Chest pain or discomfort	0.7	1.1	2.5	-1.0	-0.1	1.3	1.2	1.1	1.1	-0.6	0.4	0.1	1.5	1.6
Had major operations	0.7	0.8	1.7	-1.3	1.2	0.8	1.2	-0.0	0.0	-0.5	0.7	1.1	1.3	-0.1
Age at last live birth	0.3	0.5	1.2	-0.1	-0.3	0.2	-0.8	-0.6	-1.1	-0.2	-0.3	-1.0	-0.7	-1.1
Family relationship satisfaction	0.8	1.0	2.5	0.7	-1.1	-0.4	-0.5	-1.6	-0.9	1.6	0.2	-1.6	0.3	0.3
Leg pain on walking	1.6	2.0	5.9	1.2	-2.4	-1.8	-1.5	-0.9	-1.2	1.4	-1.2	-1.5	-1.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.6	1.9	-0.2	-1.1	-0.9	-0.1	0.4	1.6	0.2	-1.1	-0.9	1.2
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.6	1.6	0.7	-1.0	-0.5	0.0	1.3	1.4	-1.0	-0.8	-0.4	0.9
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.4	-0.8	-0.3	0.1	-0.4	-0.3	-0.6	-1.3	-0.8	0.3	-0.5	-1.8
Medication: Aspirin	1.0	1.4	4.5	-1.9	-0.2	0.6	0.3	1.0	0.9	-1.8	-0.7	0.7	-0.4	-2.1
Supplements: Vitamin C	0.3	0.3	2.2	0.9	-0.0	-0.4	-0.1	-0.4	0.0	1.5	0.7	0.1	0.0	0.3
Knee pain experienced in last month	0.1	0.2	1.1	-0.5	-0.5	-0.2	-0.1	-0.2	1.1	-0.1	0.5	0.5	-0.2	-0.5
Hypertension (Self-reported)	0.6	1.5	6.8	-1.8	0.1	0.1	-0.9	-0.1	0.4	-2.6	-1.3	-0.3	-1.2	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	4.3	0.4	1.9	-0.6	0.7	0.3	2.1	0.8	1.4	0.4	1.0	1.4
Illnesses of father: Heart disease	1.0	1.4	6.2	0.9	-1.2	-1.3	-1.3	-0.4	-2.5	0.5	-0.3	-1.3	-0.9	-0.5
Illnesses of siblings: Diabetes	0.5	0.6	1.9	0.8	1.4	-1.0	-0.7	1.0	-0.3	0.3	0.3	0.2	-0.6	0.9
Smoking status: Previous	1.8	2.6	5.6	1.3	-1.4	-1.8	-2.4	-1.6	0.3	0.8	-1.6	-2.0	-2.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.7	9.9	-2.7	2.5	3.1	2.8	2.4	2.4	-2.4	1.5	2.3	2.4	0.4
Whole body fat-free mass	0.2	1.1	2.8	1.2	-0.1	-1.1	-1.4	-0.8	-0.9	0.6	-1.2	-0.8	-1.7	0.6
Leg fat-free mass (right)	0.3	1.3	3.3	1.1	-0.2	-1.3	-1.5	-1.0	-1.1	0.5	-1.5	-1.2	-1.8	0.2
Arm fat percentage (left)	0.2	1.0	2.5	0.5	-0.1	-1.2	-1.3	-0.9	-0.7	0.2	-1.3	-1.6	-1.3	-0.5
Average weekly red wine intake	1.7	2.5	6.6	-2.5	1.8	1.8	1.3	1.2	0.0	-2.6	0.9	0.7	1.4	-1.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.2	-0.6	-1.5	1.4	0.5	-0.8	-0.4	0.0	0.6	0.4	0.2	-0.4
Mood swings	0.2	0.4	1.2	0.7	-0.6	-0.7	-0.9	0.2	0.4	0.3	0.6	-0.5	-1.1	0.2
Loneliness, isolation	2.0	2.7	7.7	1.4	-2.8	-1.1	-1.3	-2.3	-1.4	2.4	0.0	-1.7	-1.0	-0.6
Long-standing illness, disability or infirmity	0.8	1.3	2.7	-1.6	0.7	1.2	1.5	0.7	1.6	-0.8	1.0	0.7	1.4	-0.0
Ever had bowel cancer screening	0.4	0.5	1.7	0.7	0.8	-0.3	0.1	-0.7	-0.0	1.1	0.9	-0.4	0.2	1.3
Diabetes diagnosed by doctor	1.2	1.9	3.5	-1.6	1.3	1.5	1.3	1.4	0.3	-1.8	1.9	1.6	1.2	0.4
Ever had stillbirth, spontaneous miscarriage or termination	6.5	6.9	12.9	0.3	-2.8	-2.1	-2.9	-2.9	-2.5	0.1	-3.0	-3.2	-3.0	-3.6
Friendships satisfaction	0.3	0.4	2.0	-0.1	-1.2	-0.1	-0.5	0.2	-1.4	-0.4	0.0	-0.2	-0.3	-0.4
Qualifications: nursing, teaching	0.4	0.6	3.1	0.7	0.1	-0.6	-0.7	-0.7	-1.0	0.5	-0.3	-1.8	-0.5	0.1
Commuting to job workplace: Walk	1.8	1.9	7.1	-2.0	-0.2	1.4	0.7	0.8	-0.7	-2.3	-0.1	2.7	0.2	-1.0
Eye problems/disorders: Cataract	1.0	1.1	2.3	-0.8	-0.1	1.4	1.5	0.8	0.8	-0.2	1.5	1.2	1.4	0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.9	1.0	-0.6	-1.1	-1.6	-1.4	-1.3	0.5	-0.8	-1.1	-2.0	0.1
Medication for cholesterol	0.2	0.4	1.6	0.3	0.8	0.3	0.5	0.1	-1.3	0.4	-0.5	0.2	1.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.8	1.1	-0.8	-0.6	-1.1	-1.7	-0.5	0.9	-0.8	-1.6	-0.9	0.7
Back pain experienced in last month	0.4	0.6	2.9	-0.6	1.3	-0.1	0.7	0.8	1.7	-0.4	0.4	0.6	0.4	0.0
Mineral and other dietary supplements	2.2	2.9	4.6	-1.7	1.5	1.9	1.7	2.1	1.5	-2.0	1.7	2.2	1.6	0.2
Breast cancer (self-reported)	0.2	0.3	0.8	-0.5	-0.0	0.6	0.8	0.2	-0.3	-0.2	0.8	0.9	0.4	-0.0
Asthma (self-reported)	0.8	1.6	4.8	-1.5	1.4	1.2	0.7	1.2	2.2	-1.8	0.7	1.0	0.3	-0.0
Osteoporosis (self-reported)	0.7	0.8	1.3	1.2	-0.7	-1.1	-0.9	-0.7	-1.1	0.7	0.2	-1.0	-0.8	1.1
Osteoarthritis (self-reported)	0.9	1.2	2.7	1.3	-0.7	-1.6	-1.1	-1.5	-0.8	1.4	-0.7	-0.9	-0.8	-0.3
Medication: Aspirin	1.0	1.3	5.4	-1.8	-0.3	0.3	0.1	0.7	0.9	-1.7	-1.0	0.4	-0.6	-2.3
Medication: Gliclazide	0.9	1.1	3.2	-1.8	0.2	0.6	0.8	0.9	-0.8	-1.8	1.1	0.9	0.7	-0.7
Illnesses of father: None of the above (group 1)	1.3	1.7	2.8	-1.3	1.4	1.4	1.6	1.3	1.6	-1.0	0.4	1.7	1.5	-0.0
Smoking status: Current	0.8	1.3	4.0	-1.2	-0.0	2.0	1.5	0.7	-0.2	-0.7	0.9	1.2	1.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	-0.3	-0.4	0.3	0.5	0.2	-0.3	0.1	0.7	0.4	0.6	-0.8
Whole body water mass	0.2	1.1	2.7	1.2	-0.1	-1.1	-1.4	-0.8	-1.0	0.7	-1.2	-0.9	-1.6	0.6
Leg predicted mass (right)	0.2	1.2	3.0	1.1	-0.1	-1.2	-1.4	-0.9	-1.1	0.5	-1.4	-1.2	-1.7	0.2
Arm fat mass (left)	0.6	2.6	5.3	1.2	-0.7	-2.0	-2.2	-1.4	-1.3	0.6	-2.1	-2.1	-2.3	-0.5
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	-0.6	0.7	-0.6	-0.0	0.7	0.2	-0.9	-0.0	0.3	-0.2	0.6
Average weekly champagne plus white wine intake	0.6	0.9	1.9	0.6	-0.7	-0.8	-1.2	-1.3	-0.8	0.8	-0.6	-0.5	-1.4	-1.1
Miserableness	0.6	1.0	3.5	0.8	-1.9	-0.6	-0.9	-1.0	-1.0	1.1	-0.9	-0.7	-1.0	-0.4
Guilty feelings	2.1	3.1	6.1	2.4	-1.7	-2.5	-1.8	-1.3	-1.5	2.1	-0.1	-1.5	-2.0	1.3
Wears glasses or contact lenses	1.2	1.3	3.8	0.1	-1.9	-1.3	-0.9	-1.1	-0.6	0.5	-1.7	-1.1	-0.9	-1.3
Ever taken oral contraceptive pill	2.7	3.0	6.9	-0.4	1.7	1.1	2.2	1.6	1.7	0.2	2.3	1.6	2.6	1.9
Hearing aid user	0.8	0.9	1.5	-1.1	1.1	0.7	0.9	1.1	1.2	-0.7	0.6	1.1	0.8	-0.3
Mother’s age at death	1.2	1.4	4.4	-1.9	-0.6	1.1	0.5	0.9	1.0	-2.1	-0.2	1.3	0.2	-1.6
Financial situation satisfaction	0.5	0.6	1.2	1.0	-1.0	-0.7	-0.4	0.7	-0.3	0.9	-0.2	-1.0	0.2	1.1
Tinnitus: Yes, now most or all of the time	3.8	4.5	7.6	-2.8	1.5	2.6	2.5	1.6	1.3	-2.3	2.5	2.5	2.2	0.1
Commuting to job workplace: Public transport	1.0	1.2	3.5	0.7	-0.8	-0.9	-1.6	-0.6	-1.1	0.2	-1.9	-0.8	-1.8	-0.1
Eye problems/disorders: Glaucoma	0.9	1.0	4.6	0.2	1.6	-0.1	0.5	1.2	2.1	-0.1	0.8	-0.2	0.6	1.2
Medication: Blood pressure	0.5	0.9	4.5	-1.3	-0.6	-0.1	-0.8	0.2	0.1	-2.1	-0.3	0.1	-1.2	-1.0
Pain type(s) experienced in last month: Hip pain	1.2	1.5	5.5	0.4	1.5	-0.4	0.7	1.2	1.3	0.2	2.0	0.4	0.9	2.3
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.1	1.3	-0.6	-1.8	-1.4	-1.1	-0.7	1.0	-1.1	-1.5	-1.4	0.0
High cholesterol (Self-reported)	0.2	0.3	1.1	-0.6	-0.0	-0.7	-0.2	0.7	1.1	-0.9	0.4	0.0	-0.5	-0.2
Medication: Bendroflumethiazide	1.5	2.2	5.5	0.8	-0.8	-1.9	-2.3	-1.5	-1.4	0.1	-1.2	-1.5	-2.2	-1.0
Medication: Paracetamol	2.9	4.5	13.2	1.5	-2.1	-2.5	-2.3	-2.0	-1.4	1.2	-2.3	-3.6	-1.9	-1.4
Medication: Lisinopril	2.2	2.8	5.9	-2.4	1.6	1.5	1.5	1.5	1.5	-2.4	2.0	1.3	1.4	-0.2
Medication: Atorvastatin	2.9	3.6	9.0	-2.3	0.9	1.7	1.8	2.9	1.8	-3.0	1.1	2.1	1.1	-0.1
Illnesses of father: High blood pressure	1.1	1.4	3.7	0.8	-1.9	-0.6	-1.4	-1.3	-1.8	0.5	-0.2	-1.0	-1.4	0.2
Alcohol drinker status: Never	0.4	0.5	3.2	0.2	-1.8	-0.2	-0.4	-0.7	-0.8	0.5	-0.3	-0.8	-0.1	-0.4
Ever smoked	1.7	2.9	6.1	0.9	-1.5	-1.2	-2.5	-2.2	-0.9	0.4	-2.4	-1.8	-2.4	-1.3
Basal metabolic rate	0.2	1.1	3.0	1.1	-0.2	-1.2	-1.5	-0.7	-0.9	0.5	-1.3	-1.0	-1.7	0.5
Leg fat percentage (left)	0.6	2.0	4.2	1.4	-0.5	-2.0	-2.0	-1.0	-0.4	0.7	-1.6	-2.0	-1.9	0.2
Arm fat-free mass (left)	0.6	3.0	6.7	2.0	-0.9	-2.1	-2.5	-1.3	-1.3	1.3	-1.8	-1.7	-2.6	0.4
Number of operations (self-reported)	0.6	1.0	3.2	-0.6	1.1	0.2	0.9	1.0	1.1	-0.5	1.8	1.2	0.6	0.7
Average weekly beer plus cider intake	3.2	4.6	7.1	2.5	-2.7	-2.1	-2.6	-2.3	-1.7	2.3	-1.8	-1.8	-2.5	-0.2
Irritability	0.8	1.3	4.2	-0.8	0.8	0.3	0.2	2.0	1.9	-1.8	0.6	1.1	-0.2	-0.1
Risk taking	3.1	4.5	10.4	3.0	0.1	-2.0	-2.3	-2.3	-1.1	2.9	-0.7	-3.2	-1.6	1.7
Ever had prostate specific antigen (PSA) test	1.6	1.8	3.6	1.2	-0.5	-1.9	-1.5	-1.2	-1.6	1.3	-1.2	-1.8	-0.9	-1.1
Fractured/broken bones in last 5 years	1.1	1.4	3.1	-1.6	1.1	0.7	1.4	0.6	0.7	-1.5	1.1	1.8	1.2	-0.0
Age started oral contraceptive pill	0.1	0.1	0.7	0.0	0.1	-0.2	-0.1	-0.1	0.2	0.0	-0.8	-0.1	-0.1	-0.2
Diastolic blood pressure, automated reading	1.9	5.8	14.5	-3.8	0.1	3.3	1.9	1.0	2.0	-3.6	0.6	3.5	0.9	-2.0
Ever depressed for a whole week	0.9	1.1	3.6	1.6	0.7	-0.2	0.2	-0.2	0.3	1.7	0.3	-1.2	0.7	1.9
Unable to work because of sickness or disability	0.8	1.1	2.8	1.7	-0.5	-1.3	-1.0	-0.3	-0.3	1.4	-0.1	-1.0	-0.9	1.5
Commuting to job workplace: Cycle	0.3	0.4	2.1	0.6	-0.4	-1.1	-0.2	0.1	-1.4	0.6	-0.0	-0.2	-0.2	0.4
Myopia	0.3	0.5	1.6	0.8	0.5	-1.0	-0.6	0.3	-0.2	0.4	-0.4	-1.3	-0.2	0.9
Vascular/heart problems diagnosed by doctor	0.6	1.7	9.0	2.3	-0.8	-1.0	-0.1	-0.9	-1.1	3.0	0.1	-0.7	0.3	0.9
Cholesterol lowering medication	0.3	0.5	3.2	-0.2	-0.7	-0.2	-0.3	0.1	1.8	-0.3	0.9	-0.3	-0.6	0.3
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.1	0.6	1.3	-1.0	-0.2	1.5	1.6	0.0	0.5	-0.2	0.0	1.8
Pain experienced in last month	0.1	0.2	0.9	0.4	0.6	0.5	0.0	0.6	-0.4	-0.2	-1.0	0.0	0.2	0.5
Supplements: Calcium	0.2	0.2	0.3	-0.5	0.3	0.3	0.6	0.3	-0.2	-0.4	0.6	-0.3	0.6	0.4
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	-0.7	-0.1	0.5	0.1	-0.4	-0.4	-0.8	-0.2	0.8	-0.7	-0.2
Heart attack/myocardial infarction (self-reported)	1.6	2.0	5.2	-2.3	1.4	1.6	1.7	1.1	0.9	-1.6	0.7	1.3	1.3	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	3.3	-1.3	1.3	1.5	1.8	1.1	1.1	-1.0	1.7	1.2	1.7	0.9
Heart disease (siblings)	2.0	2.5	5.5	-2.3	1.3	1.8	1.5	1.4	1.2	-2.1	0.9	1.7	1.4	-1.1
Alcohol drinker status: Previous	0.5	0.6	1.1	0.3	-0.7	-1.0	-0.9	-0.9	0.2	0.2	-0.6	-1.1	-1.1	-0.9
Pack years of smoking	0.6	0.9	3.0	-0.9	0.5	-0.3	-1.0	0.1	-1.1	-1.7	-1.2	-0.4	-1.0	-1.0
Impedance of whole body	4.3	22.1	32.4	-5.7	3.4	5.5	5.6	5.1	4.1	-5.2	4.2	5.0	5.0	-0.6
Leg fat mass (left)	0.7	2.9	5.6	1.7	-0.7	-2.3	-2.4	-1.4	-0.7	1.0	-2.0	-2.1	-2.4	0.2
Arm predicted mass (left)	0.5	2.7	6.5	2.0	-0.7	-2.0	-2.4	-1.2	-1.1	1.2	-1.7	-1.5	-2.5	0.5