Best TWAS P=2.46e-12 · Best GWAS P=4.03e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PPFIA2 | 0.15 | 0.09 | enet | 19 | 0.07 | 3.4e-06 | -6.9 | -6.7 | 1.5e-11 | 0.91 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Esophagus Muscularis | PPFIA2 | 0.12 | 0.14 | lasso | 3 | 0.14 | 1.1e-08 | -6.9 | -7.0 | 2.7e-12 | 0.99 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Lung | PPFIA2 | 0.13 | 0.10 | lasso | 3 | 0.09 | 2.9e-07 | -6.9 | -7.0 | 2.5e-12 | 0.96 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Nerve Tibial | PPFIA2 | 0.20 | 0.09 | enet | 36 | 0.08 | 2.1e-06 | -6.6 | -5.8 | 5.0e-09 | 0.78 | 0.03 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PPFIA2 | 0.11 | 0.08 | enet | 17 | 0.08 | 1.1e-09 | -6.9 | -6.6 | 4.9e-11 | 0.97 | 0.01 | 0.99 | FALSE |