Best TWAS P=7.55e-09 · Best GWAS P=1.69e-23 conditioned to 7.48e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | SURF1 | 0.10 | 0.00 | lasso | 5 | 0.00 | 0.2480 | -6.5 | 5.8 | 7.5e-09 | 0.24 | 0.06 | 0.07 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FAM163B | 0.06 | 0.01 | lasso | 3 | 0.02 | 0.0024 | -6.5 | -5.3 | 1.3e-07 | -0.14 | 0.04 | 0.03 | FALSE |