Best TWAS P=3.81e-08 · Best GWAS P=1.05e-07 conditioned to 0.185
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | AS3MT | 0.17 | 0.16 | lasso | 9 | 0.15 | 4.5e-18 | 4.6 | -5.4 | 7.5e-08 | -0.65 | 0.16 | 0.83 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | NT5C2 | 0.13 | 0.07 | enet | 12 | 0.08 | 5.0e-05 | 3.8 | 5.3 | 1.3e-07 | 0.47 | 0.23 | 0.73 | TRUE |
| 3 | GTEx | Brain Cerebellar Hemisphere | NT5C2 | 0.15 | 0.10 | enet | 8 | 0.07 | 9.2e-03 | 4.7 | -5.2 | 1.8e-07 | -0.64 | 0.08 | 0.44 | FALSE |
| 4 | GTEx | Liver | ACTR1A | 0.15 | 0.00 | lasso | 10 | 0.00 | 4.6e-01 | -2.5 | -5.5 | 5.1e-08 | -0.56 | 0.04 | 0.36 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C10orf32 | 0.06 | 0.06 | blup | 54 | 0.08 | 1.2e-07 | 4.8 | -5.2 | 2.3e-07 | -0.73 | 0.05 | 0.94 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | AS3MT | 0.04 | 0.05 | enet | 3 | 0.04 | 8.6e-06 | 5.1 | -5.2 | 2.6e-07 | -0.77 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Rectum Adenocarcinoma | C10orf32 | 0.17 | 0.14 | blup | 52 | 0.14 | 3.2e-04 | 5.1 | -5.5 | 3.8e-08 | -0.77 | 0.01 | 0.81 | TRUE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | AS3MT | 0.23 | 0.18 | lasso | 3 | 0.18 | 1.8e-17 | 5.2 | -5.2 | 1.7e-07 | -0.76 | 0.00 | 0.99 | FALSE |