Best TWAS P=1.52e-07 · Best GWAS P=8.57e-07 conditioned to 0.0202
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | MSH6 | 0.15 | 0.17 | enet | 12 | 0.16 | 3.5e-12 | 4.1 | 5.2 | 2.4e-07 | 0.58 | 0.06 | 0.84 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | MSH6 | 0.11 | 0.06 | enet | 6 | 0.12 | 5.3e-12 | 4.1 | 5.2 | 1.5e-07 | 0.58 | 0.01 | 0.94 | TRUE |