TWAS hub - MSH6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1470	0.0560	4.5e-03	0.004	NA	0.036	NA	0.018	1.4e-01	NA	6.3e-04	NA	1.3e-02
2	GTEx	Artery Tibial	0.0857	0.0372	5.1e-03	0.036	NA	0.003	NA	0.025	7.8e-04	NA	1.8e-01	NA	4.1e-03
3	GTEx	Esophagus Muscularis	0.1100	0.0550	8.9e-03	0.035	NA	0.056	NA	0.040	3.3e-03	NA	2.5e-04	NA	1.7e-03
4	GTEx	Lung	0.1641	0.0462	1.9e-04	0.015	NA	0.032	NA	0.044	2.2e-02	NA	1.6e-03	NA	2.4e-04
5	GTEx	Nerve Tibial	0.1300	0.0404	6.6e-05	0.034	NA	0.038	NA	0.054	1.9e-03	NA	1.1e-03	NA	1.0e-04
6	GTEx	Skin Sun Exposed Lower leg	0.1990	0.0510	1.4e-06	0.115	NA	0.138	NA	0.151	9.2e-10	NA	1.6e-11	NA	1.7e-12
7	GTEx	Testis	0.2570	0.0730	8.2e-04	0.191	NA	0.165	NA	0.187	7.3e-09	NA	8.6e-08	NA	1.0e-08
8	GTEx	Thyroid	0.1480	0.0410	1.4e-05	0.171	NA	0.159	NA	0.158	4.5e-13	NA	3.5e-12	NA	3.6e-12
9	ROSMAP	Brain Pre-frontal Cortex	0.0700	0.0251	3.8e-05	0.048	0.026	0.050	0.028	0.039	7.2e-07	2.5e-04	5.1e-07	1.2e-04	8.5e-06
10	YFS	Blood	0.1018	0.0205	7.8e-16	0.037	0.069	0.076	0.076	0.079	4.4e-12	1.0e-21	8.2e-24	8.6e-24	2.0e-24
11	TCGA	Breast Invasive Carcinoma	0.0521	0.0173	1.9e-10	0.028	0.056	0.057	NA	0.053	1.5e-06	1.4e-11	1.1e-11	NA	4.0e-11
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0684	0.0285	4.5e-06	0.023	0.056	0.037	NA	0.028	1.0e-03	6.2e-07	4.5e-05	NA	3.6e-04
13	TCGA	Brain Lower Grade Glioma	0.0313	0.0150	6.0e-04	0.008	0.012	0.004	NA	0.002	3.3e-02	1.5e-02	1.1e-01	NA	1.7e-01
14	TCGA	Prostate Adenocarcinoma	0.0494	0.0238	2.2e-04	0.031	0.016	0.013	NA	0.008	2.8e-04	7.6e-03	1.3e-02	NA	4.0e-02
15	TCGA	Thyroid Carcinoma	0.1130	0.0350	1.1e-11	0.058	0.117	0.123	NA	0.117	2.3e-06	2.0e-11	5.3e-12	NA	1.9e-11
16	TCGA	Uterine Corpus Endometrial Carcinoma	0.1210	0.0650	9.6e-03	0.058	0.043	0.024	NA	0.032	1.1e-02	2.4e-02	7.2e-02	NA	4.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Smoking status: Previous	11.3	16.9	27.5	-1.9	-4.5	-4.3	-3.6	-4.9	-3.5	-3.9	-4.6	-4.3	-2.9	-4.1	-3.9	-4.8	-4.8	-5.2	-3.0
Ever smoked	10.6	18.5	35.3	-1.8	-5.2	-4.7	-4.4	-4.6	-2.7	-4.8	-5.9	-4.6	-3.1	-4.0	-3.9	-4.6	-4.8	-5.2	-2.3
Past tobacco smoking	9.5	17.4	27.6	1.7	4.7	4.5	4.0	4.7	3.2	4.2	5.2	4.6	2.9	4.0	3.9	4.8	4.8	5.2	2.5
Lung FVC	7.3	37.2	56.1	-4.8	-5.7	-6.4	-6.0	-7.5	-6.2	-5.8	-6.8	-4.8	-6.2	-7.0	-5.3	-5.6	-7.1	-6.9	-4.5
Age when periods started (menarche)	6.5	15.6	32.9	1.9	5.7	3.4	5.2	2.8	0.9	5.7	5.2	0.4	3.1	2.7	4.4	5.3	4.1	4.7	1.8
Smoking Status	6.4	15.2	26.9	-2.7	-5.2	-4.1	-3.7	-3.7	-1.0	-4.7	-5.2	-4.5	-1.9	-2.9	-3.8	-4.9	-4.2	-5.0	-1.5
Fasting Glucose	6.0	7.1	17.0	-0.6	-1.9	-2.9	-2.4	-3.0	-3.6	-1.8	-2.2	-3.5	-1.8	-4.1	-1.6	-1.8	-3.5	-3.2	-2.2
Pulse rate, automated reading	5.8	18.8	42.9	2.5	5.9	4.0	3.5	4.7	1.3	4.8	5.3	3.9	2.5	2.5	5.6	6.5	4.3	5.5	2.2
Blood clot in the leg (DVT)	4.9	6.3	9.2	-0.1	-2.5	-2.9	-1.8	-2.6	-2.3	-2.1	-2.6	-2.6	-2.1	-2.3	-2.8	-2.9	-3.0	-2.9	-2.9
Medication: Co-codamol	4.8	5.5	9.2	-2.5	-3.0	-1.5	-1.8	-2.5	-1.0	-2.5	-2.9	-2.4	-1.6	-2.0	-2.5	-2.7	-2.9	-3.0	-1.5
Chronic bronchitis/emphysema (father)	4.8	5.6	8.8	-2.4	-2.9	-1.8	-2.3	-2.5	-1.7	-3.0	-2.7	-1.0	-2.2	-1.9	-2.4	-3.0	-2.5	-2.9	-1.8
Qualifications: NVQ or HND or HNC or equivalent	4.6	5.5	10.4	-0.7	-2.1	-2.4	-1.7	-2.8	-3.1	-2.0	-2.4	-2.2	-2.2	-3.2	-1.7	-2.0	-2.9	-2.7	-2.1
Deep venous thrombosis (DVT) (self-reported)	4.6	5.9	8.7	0.1	-2.6	-2.9	-1.7	-2.6	-1.9	-2.1	-2.6	-2.5	-1.9	-2.1	-2.8	-2.9	-2.9	-3.0	-2.9
Hair/balding pattern: Pattern 4	3.8	9.2	16.4	0.8	2.6	3.2	1.7	3.8	3.4	2.4	3.4	2.1	3.0	4.0	1.9	2.4	4.0	3.7	3.8
Frequency of depressed mood in last 2 weeks	3.6	5.1	9.4	-1.1	-2.7	-1.5	-2.5	-1.7	-1.4	-2.8	-2.6	-1.4	-2.2	-2.4	-2.4	-2.6	-2.9	-3.1	-1.7
Illnesses of father: High blood pressure	3.6	4.4	12.5	-1.2	-1.1	-2.1	-0.9	-2.7	-3.5	-0.9	-1.3	-2.8	-2.0	-3.5	-1.1	-1.0	-2.4	-2.2	-1.9
Nervous feelings	3.5	6.6	11.7	1.2	2.2	2.7	1.3	3.3	3.1	1.3	3.0	3.3	1.7	3.4	2.2	2.4	3.0	3.1	1.9
Hair/balding pattern: Pattern 2	3.5	4.4	7.5	-2.4	-1.7	-2.0	-2.2	-1.7	-2.7	-1.5	-2.0	-2.3	-1.8	-2.5	-2.0	-1.9	-2.7	-2.1	-1.3
Wears glasses or contact lenses	3.4	3.9	7.0	-1.1	2.3	1.7	1.3	2.2	0.9	2.3	2.6	2.6	1.4	2.2	1.0	1.6	2.2	2.6	2.0
Emphysema/chronic bronchitis	3.3	3.7	7.8	0.5	-1.7	-2.3	-0.5	-2.4	-2.2	-1.7	-1.9	-1.4	-1.9	-2.6	-0.4	-1.2	-2.3	-2.4	-2.8
HbA1C	3.0	3.3	6.3	-1.1	-1.5	-1.4	-1.7	-1.0	-2.3	-1.9	-1.1	-0.8	-2.5	-2.4	-2.4	-1.9	-2.4	-1.9	-1.7
Waist Hip Ratio (WHR)	2.9	13.1	22.9	1.5	3.8	4.1	3.2	4.4	3.1	3.8	4.5	1.9	3.1	4.2	2.1	3.2	4.8	4.4	3.5
Forced vital capacity (FVC), Best measure	2.9	10.7	17.2	-2.9	-3.6	-3.7	-3.5	-4.0	-1.5	-3.6	-4.2	-2.6	-3.1	-2.8	-2.3	-3.2	-3.7	-4.0	-2.4
Fractured/broken bones in last 5 years	2.7	3.4	7.1	-1.2	-1.8	-2.1	-1.4	-2.6	-2.0	-1.4	-2.0	-1.3	-1.2	-2.2	-1.6	-1.9	-2.1	-2.7	-1.5
Townsend deprivation index at recruitment	2.6	3.7	13.5	-3.7	-2.5	-1.4	-1.2	-1.2	-1.3	-1.9	-2.1	-2.0	0.1	-1.4	-2.0	-2.5	-1.6	-2.5	0.0
Had menopause	2.6	3.2	6.5	-1.3	-2.5	-1.5	-2.1	-2.1	-0.6	-2.4	-2.4	-0.8	-1.6	-1.1	-1.8	-2.0	-1.8	-2.0	-1.2
Forced vital capacity (FVC)	2.5	9.8	16.8	-3.1	-3.3	-3.6	-4.1	-3.4	-1.5	-3.5	-3.9	-1.5	-3.3	-2.7	-2.4	-3.1	-3.6	-3.5	-2.0
Qualifications: A levels/AS levels or equivalent	2.5	5.6	13.7	0.3	3.0	1.4	1.3	3.1	1.6	2.5	2.6	3.7	1.1	2.5	1.6	2.2	2.7	3.4	1.9
Breastfed as a baby	2.5	3.1	7.3	-0.8	-1.7	-2.5	-1.9	-2.2	-1.2	-1.8	-2.7	-1.8	-1.7	-2.2	-0.4	-0.7	-2.0	-1.9	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.7	7.1	-1.6	-1.5	-1.9	-0.8	-1.6	-1.2	-1.1	-1.3	-2.7	-0.4	-1.9	-1.5	-1.8	-2.2	-2.2	-1.1
Fluid intelligence score	2.4	4.9	10.1	-0.0	2.9	1.1	1.9	1.9	1.9	2.2	2.1	3.2	1.2	2.3	2.6	2.8	2.9	2.8	1.4
Risk taking	2.4	3.5	10.1	-3.2	-2.6	-2.0	-2.8	-1.1	0.9	-2.3	-2.7	0.3	-1.1	-0.6	-1.1	-2.0	-1.6	-1.7	0.7
Depression (Nagel 2018)	2.3	3.5	7.4	-1.3	-2.4	-1.3	-2.3	-1.1	-0.9	-2.7	-2.3	-1.1	-1.8	-1.7	-2.2	-2.1	-2.0	-2.3	-0.7
Intelligence (Savage-Jansen 2018)	2.3	7.0	15.9	-0.6	2.4	1.6	2.1	2.6	3.0	2.2	2.5	4.0	2.5	3.4	1.8	1.9	3.6	3.1	2.9
Ovarian Cancer	2.3	3.1	14.1	0.8	-0.2	-0.9	0.1	-2.3	-2.6	-0.5	-0.7	-1.3	-2.4	-2.5	-0.1	-0.2	-2.3	-1.4	-3.8
Schizophrenia (2014)	2.3	5.1	13.8	-2.7	-2.7	-2.4	-2.5	-3.4	-0.2	-2.2	-2.7	-3.7	-0.5	-1.4	-1.4	-1.9	-1.6	-2.7	0.3
Heel T-Score	2.3	18.0	31.7	4.5	4.6	5.4	3.5	4.7	2.6	3.9	4.7	5.6	1.5	3.2	5.5	5.0	4.2	4.7	1.0
Hand grip strength (right)	2.3	6.3	14.5	-1.9	-1.9	-3.8	-3.1	-2.7	-2.1	-2.4	-3.0	-1.5	-2.9	-3.2	-1.1	-1.1	-3.0	-2.6	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.2	8.9	1.4	2.0	2.8	1.2	2.9	2.1	1.7	2.6	3.0	1.5	2.3	2.4	2.2	2.7	2.5	2.2
Commuting to job workplace: Cycle	2.3	2.7	11.6	-3.4	-2.2	-0.8	-1.8	-1.7	-0.1	-2.0	-1.7	-0.2	-1.2	-0.8	-1.4	-2.1	-1.4	-1.8	-0.0
Hypothyroidism (self reported)	2.2	5.2	18.0	3.3	1.8	4.2	0.9	2.7	1.8	1.1	2.6	2.4	0.1	1.8	2.0	2.5	2.1	2.5	0.7
Average weekly beer plus cider intake	2.2	3.2	7.1	-1.4	-2.6	-1.9	-1.6	-1.5	-0.7	-1.8	-2.2	-1.2	-0.7	-1.3	-1.8	-2.7	-2.1	-2.5	-0.9
Unable to work because of sickness or disability	2.2	2.9	6.2	-2.4	-2.3	-1.7	-0.8	-1.9	-1.1	-1.9	-2.5	-1.1	-0.6	-2.1	-0.1	-1.1	-1.8	-2.4	-0.7
Average weekly fortified wine intake	2.1	2.5	13.0	0.5	1.4	1.6	-0.4	2.8	0.7	0.5	1.9	3.6	-1.4	0.6	1.1	1.8	0.8	1.6	0.0
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.3	7.7	-2.0	-2.8	-1.3	-1.3	-1.1	-0.0	-2.4	-2.3	-1.1	-0.9	-1.0	-2.2	-2.6	-2.1	-2.5	-0.8
Happiness	2.1	2.5	4.8	1.1	1.9	1.1	1.6	1.0	1.4	1.8	1.9	1.1	1.7	1.6	2.2	1.6	1.7	1.7	1.2
Age at first live birth	2.1	3.7	9.0	2.3	2.1	3.0	0.8	1.8	1.1	1.1	2.1	2.8	-0.3	1.5	2.6	2.2	1.8	2.3	0.4
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	6.1	1.3	2.2	2.0	1.6	1.3	-0.0	1.9	1.5	0.7	0.8	0.9	1.4	2.5	1.5	2.3	0.9
Schizophrenia (2018)	1.9	3.9	11.5	-2.8	-2.2	-2.0	-1.8	-2.9	-0.7	-1.6	-2.6	-3.4	-0.4	-1.4	-0.7	-1.3	-1.4	-2.3	0.0
Mean Putamen Volume	1.9	2.2	8.8	1.7	-1.5	0.0	-0.2	-1.0	-0.8	-1.7	-1.3	-1.0	-2.0	-1.6	-0.3	-1.0	-1.8	-1.7	-3.0
Lupus	1.9	2.9	7.5	2.7	1.1	2.0	1.4	1.3	2.2	1.4	1.7	1.1	1.7	2.1	1.4	1.2	2.0	1.6	1.3
Lung FEV1/FVC ratio	1.9	9.4	18.6	2.9	4.2	2.7	4.3	3.1	0.6	4.2	4.2	2.0	2.2	2.1	2.5	3.4	2.9	3.7	0.5
Hypothyroidism/myxoedema (self-reported)	1.9	3.6	12.7	3.2	1.4	3.6	0.6	2.1	1.7	0.9	2.3	1.6	0.1	1.6	1.7	2.0	1.8	2.0	0.8
Migraine (self-reported)	1.9	2.4	6.9	-0.2	0.8	1.7	0.1	1.5	2.0	0.4	1.4	2.6	0.2	1.4	2.6	2.2	1.6	1.5	1.1
Type 2 Diabetes (T2D) (2012)	1.8	2.1	5.7	-1.2	-1.3	-0.8	-2.4	-0.6	-0.5	-1.9	-1.6	-0.5	-1.9	-0.6	-2.1	-2.0	-1.8	-1.1	-0.6
Respiratory disease	1.8	4.0	9.1	-0.2	-2.6	-1.1	-3.0	-1.9	-1.4	-2.8	-2.0	-0.8	-2.4	-2.6	-1.4	-1.4	-2.3	-2.6	-1.1
Pulse rate	1.8	3.1	9.8	1.8	2.6	1.6	1.1	1.6	-0.6	1.8	2.2	1.0	0.7	-0.1	2.8	3.1	1.2	1.9	0.2
Bipolar Disorder or Schizophrenia	1.6	3.9	15.4	-3.1	-2.3	-1.9	-1.2	-2.9	0.1	-1.9	-2.8	-3.9	0.1	-0.9	-0.4	-1.1	-1.0	-2.1	0.1
Verbal and Numeric Reasoning (VNR)	1.6	3.7	15.4	-0.8	2.3	1.0	0.9	1.9	1.5	1.6	1.6	3.9	0.8	1.6	2.1	2.3	2.0	2.4	1.6
Age at First Birth	1.6	2.3	4.2	0.1	1.8	1.2	0.4	1.8	1.1	1.7	1.5	1.3	1.2	1.6	1.3	1.8	1.7	2.0	2.0
Blood Platelet Count	1.6	18.2	30.5	2.1	5.3	2.8	5.5	5.4	1.9	5.3	5.2	3.4	4.5	3.8	3.8	4.2	4.6	5.2	2.3
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	7.5	1.7	1.2	1.1	1.4	0.8	0.8	1.0	1.1	1.7	0.2	0.7	2.7	2.5	1.3	1.6	0.1
Ever used hormone-replacement therapy (HRT)	1.6	2.0	4.1	0.2	-2.0	-1.2	-1.0	-1.3	-1.1	-1.4	-1.7	-1.2	-1.0	-1.1	-2.0	-2.0	-1.7	-1.5	-1.1
Stomach or abdominal pain in last month	1.6	2.0	3.7	-1.9	-1.5	-1.5	-1.2	-0.7	-1.9	-1.5	-1.6	-0.8	-1.1	-1.5	-1.5	-1.3	-1.6	-1.5	-0.4
High blood pressure (mother)	1.6	2.3	4.3	0.5	1.5	1.0	1.1	1.6	1.3	1.7	1.6	1.2	1.6	1.6	1.6	1.6	2.1	1.7	1.9
Impedance of arm (right)	1.6	7.7	16.4	0.5	2.4	1.5	2.2	1.9	3.3	2.9	2.3	1.1	3.6	4.0	2.3	2.3	3.7	3.3	4.0
Ever depressed for a whole week	1.6	2.0	4.8	-1.2	2.2	-0.4	0.9	0.1	-1.2	2.1	1.4	0.8	1.4	0.2	1.5	1.8	1.9	1.4	1.7
Pain experienced in last month	1.6	2.7	7.7	2.8	1.6	2.5	0.5	2.2	1.2	1.3	1.4	0.9	0.7	1.5	0.9	1.6	1.7	2.0	1.5
Major Depression (MDD)	1.5	1.8	7.3	-1.4	-0.6	-2.2	0.4	-1.3	-1.4	-0.1	-1.2	-2.7	1.1	-1.2	-1.8	-1.3	-0.5	-1.3	0.2
Reaction Time	1.5	2.9	6.0	0.5	-2.2	-1.8	-1.5	-1.8	-0.2	-2.3	-2.4	-1.4	-1.6	-1.3	-1.7	-1.9	-1.8	-1.9	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	6.2	1.9	1.8	2.5	0.8	1.9	1.7	1.3	2.2	1.8	1.3	1.8	2.2	1.8	2.3	1.8	2.0
Pulse wave Arterial Stiffness index	1.5	1.7	4.5	1.1	-1.2	0.0	-0.6	-0.8	-1.2	-1.6	-0.8	0.4	-1.9	-1.6	-1.2	-1.1	-1.9	-1.4	-2.1
Knee pain experienced in last month	1.5	2.3	8.9	-1.0	-1.1	-1.8	-0.5	-1.1	-1.6	-1.1	-1.2	0.5	-1.9	-1.9	-0.6	-1.1	-2.1	-1.6	-3.0
Loneliness, isolation	1.5	2.1	5.8	0.6	-1.7	-0.7	-0.2	-0.8	-0.8	-1.7	-1.3	-0.2	-1.8	-1.6	-1.4	-1.7	-2.4	-1.8	-2.0
Asthma (self-reported)	1.5	2.9	6.1	0.1	-1.8	-0.9	-2.1	-1.6	-1.9	-2.0	-1.4	-1.1	-2.1	-2.5	-1.2	-1.1	-2.1	-2.2	-1.5
Tinnitus: Yes, now most or all of the time	1.5	1.8	5.4	2.3	1.3	0.0	1.3	1.6	0.7	1.7	2.3	1.0	1.3	1.0	-0.2	0.5	1.1	1.3	1.3
Coronary Artery Disease (CAD)	1.4	1.7	5.2	0.7	1.4	1.9	1.1	0.8	0.6	1.3	1.4	-0.7	1.4	0.5	2.3	1.9	1.3	1.0	0.9
Mouth/teeth dental problems: Dentures	1.4	2.4	7.6	0.7	-1.1	-0.3	-1.2	-1.6	-2.1	-1.7	-1.5	-0.4	-2.8	-2.3	-0.9	-0.7	-1.9	-1.5	-1.4
Mean time to correctly identify matches	1.4	2.6	6.1	-0.4	-2.2	-1.5	-2.0	-1.6	0.2	-2.3	-2.5	-1.0	-1.6	-0.9	-1.9	-1.9	-1.6	-1.7	-0.5
Impedance of whole body	1.4	6.9	16.0	0.6	1.9	1.5	2.4	1.7	3.3	2.6	2.0	0.6	4.0	4.0	1.6	1.6	3.6	2.9	3.9
Chronotype (morning person)	1.3	3.1	20.1	4.5	1.3	1.3	2.0	0.8	1.5	0.7	1.6	1.5	0.4	1.4	2.2	1.5	1.3	1.4	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.3	7.3	-1.5	-2.0	-2.4	-1.8	-2.7	-1.2	-2.0	-2.4	-1.9	-2.0	-2.0	-1.0	-1.7	-2.6	-2.6	-2.2
Impedance of arm (left)	1.3	6.0	15.4	0.3	1.6	1.1	1.9	1.6	3.5	2.2	1.8	1.0	3.4	3.9	1.5	1.4	3.3	2.7	3.8
Chronic bronchitis/emphysema (mother)	1.3	1.5	8.2	2.3	0.1	1.0	1.7	-1.2	-0.5	0.1	-0.0	-1.2	-0.3	-0.9	1.4	0.5	-0.7	-0.6	-2.9
High blood pressure (siblings)	1.3	1.9	4.0	-0.3	-1.1	-1.1	-1.5	-1.1	-2.0	-1.1	-1.4	-1.7	-1.6	-1.8	-1.4	-0.9	-1.8	-1.2	-0.8
Number of full brothers	1.3	1.6	3.1	-1.8	-1.4	-1.6	-1.1	-0.6	-1.1	-1.7	-1.6	-1.0	-0.6	-1.3	-1.4	-1.1	-1.4	-1.2	-0.2
Family relationship satisfaction	1.3	1.5	3.5	1.2	1.7	1.6	1.9	-0.1	0.4	1.6	1.4	-0.0	0.7	0.5	1.6	1.8	1.0	1.4	0.4
Alcohol drinker status: Never	1.3	1.5	5.1	-1.0	-1.1	-1.1	-1.4	-0.1	-1.1	-1.5	-1.2	-0.4	-2.3	-1.4	-0.3	-0.5	-1.4	-1.2	-1.7
Prostate Cancer	1.2	1.7	4.7	0.4	2.2	0.4	2.2	0.5	-0.9	1.9	1.9	0.1	0.8	-0.1	1.3	1.9	0.8	1.5	-1.1
Hand grip strength (left)	1.2	3.3	7.7	0.1	-0.9	-2.8	-1.7	-2.5	-1.8	-1.4	-1.8	-1.9	-1.9	-2.5	0.1	-0.1	-2.1	-1.9	-2.1
Diabetes (father)	1.2	1.5	8.8	-0.5	0.4	-3.0	0.4	-0.7	-2.7	0.8	-0.1	-0.9	0.4	-1.7	-1.3	-0.7	-0.7	-0.3	0.1
Medication: Levothyroxine sodium	1.2	2.0	7.3	2.7	0.8	2.7	0.2	1.5	0.9	0.4	1.7	1.4	-0.6	0.9	1.5	1.7	1.2	1.3	0.0
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	4.6	0.2	-1.5	-1.2	-2.1	-0.6	0.1	-2.0	-1.3	-0.0	-1.7	-1.0	-0.2	-0.6	-1.3	-1.4	-0.7
Osteoarthritis (self-reported)	1.2	1.5	6.6	0.8	-0.4	1.2	-1.3	-0.3	-1.5	-1.1	-0.4	1.8	-2.6	-1.2	-0.6	-0.6	-1.3	-0.5	-1.5
Irritability	1.2	2.0	7.5	-0.3	0.1	1.0	0.9	1.8	2.7	0.1	0.7	2.4	1.4	2.3	0.6	0.2	1.7	1.1	1.3
Ever had prostate specific antigen (PSA) test	1.2	1.4	5.6	-0.1	-0.4	-0.6	-0.5	-1.7	-0.9	-0.5	-1.1	-0.6	-2.2	-1.5	0.1	-0.2	-1.3	-1.1	-2.4
Current tobacco smoking	1.1	1.7	4.6	-1.0	-2.1	-1.5	-1.2	0.2	1.5	-1.8	-2.0	-1.2	0.2	0.0	-1.1	-1.7	-0.8	-1.3	1.0
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	7.0	1.4	0.8	0.9	1.1	0.3	0.5	0.5	-0.1	0.4	-0.4	-0.3	2.6	2.4	0.7	0.5	-1.1
Illnesses of siblings	1.1	1.5	8.4	-0.3	0.2	-0.3	0.5	0.4	2.9	0.4	0.6	1.9	1.1	1.9	1.4	0.5	1.6	0.6	1.0
Medication: Amlodipine	1.1	1.5	5.1	0.6	1.2	-0.5	0.8	1.4	1.3	1.4	1.3	1.4	1.2	2.3	0.0	-0.0	1.3	1.4	1.6
Pulse wave peak to peak time	1.1	1.2	3.9	-1.2	1.0	-0.4	0.4	0.5	1.0	1.3	0.5	-0.5	1.6	1.3	0.9	1.0	1.6	1.1	2.0
Handedness (chirality/laterality): Left-handed	1.1	1.3	5.1	-0.4	0.2	0.5	1.2	0.8	1.5	0.9	1.0	0.4	2.2	1.7	1.0	0.2	1.6	0.5	1.7
Illnesses of father: None of the above (group 1)	1.1	1.3	3.9	1.6	0.5	2.0	0.7	1.0	1.9	0.4	0.7	0.1	1.4	1.6	0.9	0.3	1.2	0.8	0.8
Diastolic blood pressure, automated reading	1.1	3.3	7.8	1.5	2.6	0.3	2.8	0.5	-0.6	2.8	2.1	-1.6	1.7	0.3	2.6	2.6	1.6	1.5	-0.2
Bipolar Disorder (2011)	1.0	0.9	3.4	-1.3	-1.5	-1.1	-0.8	-1.6	-0.5	-1.5	-1.8	0.0	-0.9	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	1.0	1.6	4.6	-1.3	-1.6	-1.5	-2.0	-1.9	-0.1	-1.2	-2.1	-1.3	-0.7	-0.6	-0.7	-0.9	-0.9	-1.1	0.5
Maternal smoking around birth	1.0	1.5	3.9	1.5	-1.4	-1.9	0.5	-1.0	0.1	-1.2	-1.3	-2.0	-0.1	-0.4	-1.1	-1.5	-1.0	-1.5	-1.2
Qualifications: CSEs or equivalent	1.0	1.3	3.3	0.3	-0.4	-1.2	-0.4	-1.6	-1.8	-0.2	-0.1	-1.8	-0.8	-1.3	-0.5	-1.2	-1.5	-1.6	-1.4
Heart attack	1.0	1.3	2.5	1.2	-1.6	0.3	-0.7	-0.7	-0.3	-1.6	-1.3	-0.6	-1.5	-0.9	-1.0	-1.2	-1.2	-1.4	-1.4
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	5.6	-1.3	-1.6	-2.4	-2.2	-2.2	-1.2	-1.8	-2.0	-1.1	-2.1	-1.8	-0.8	-1.4	-2.3	-2.2	-1.9
Exposure to tobacco smoke at home	1.0	1.2	3.2	-1.4	-1.5	-0.2	-1.0	-0.3	0.7	-1.4	-1.6	-0.3	-0.1	0.3	-1.6	-1.8	-0.4	-1.4	-0.1
Comparative body size at age 10	1.0	2.9	9.0	-0.6	-1.1	-0.7	-2.7	-0.8	-1.8	-1.6	-1.3	1.0	-3.0	-2.2	-0.5	-0.9	-2.6	-1.6	-1.9
Commuting to job workplace: Car/motor vehicle	1.0	1.2	4.2	-0.2	-1.7	-0.0	-1.7	-1.4	0.8	-1.4	-2.1	-0.5	-1.0	-0.3	-0.3	-0.8	-0.9	-1.1	-0.6
Average weekly champagne plus white wine intake	1.0	1.4	4.4	-0.0	0.5	1.1	0.0	1.3	2.1	0.7	0.5	1.2	1.4	1.9	0.7	0.6	1.4	1.2	1.7
Age started oral contraceptive pill	1.0	1.3	7.4	-0.8	0.5	-1.3	0.2	-1.7	-2.7	0.4	-0.0	-1.4	-0.4	-1.9	-0.2	0.3	-0.8	-0.4	-0.8
Alzheimer’s Disease (including proxy)	0.9	1.3	4.9	-2.2	-0.5	-1.3	-0.6	-1.0	-1.5	-0.6	-1.5	-0.1	-1.2	-1.2	-1.2	-0.6	-1.2	-0.6	-1.3
Irritable Bowel Disease (IBD)	0.9	2.1	6.2	-0.0	1.6	0.5	1.4	2.0	0.7	1.7	1.8	0.4	2.5	1.3	-0.1	0.8	1.6	1.5	2.0
Ulcerative Colitis (UC)	0.9	1.7	6.8	-0.1	1.6	-0.2	1.8	0.7	0.1	1.9	1.4	-0.6	2.6	1.0	0.3	0.8	1.7	1.1	1.6
Alcohol usually taken with meals	0.9	1.5	3.5	0.3	1.9	0.9	0.8	0.8	0.8	1.6	1.8	0.9	1.0	0.9	1.1	1.6	1.5	1.7	0.9
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.9	-1.7	1.3	0.7	0.3	0.5	-0.5	1.2	0.9	1.7	0.8	0.6	0.4	0.5	1.3	1.0	1.4
Pain all over the body in last month	0.9	1.0	3.7	-1.5	0.1	-0.7	-1.9	-0.8	-1.7	-0.3	-0.6	-0.7	-0.8	-1.7	0.2	0.4	-0.8	-0.8	-0.2
Medication: Ramipril	0.9	1.1	3.3	0.8	-0.8	-1.4	-0.0	-0.6	-1.8	-0.9	-1.2	-0.0	-1.2	-1.4	-1.3	-1.0	-0.9	-0.8	-1.1
Asthma	0.9	1.7	3.6	0.0	-1.5	-0.7	-1.9	-1.2	-1.3	-1.7	-1.1	-0.8	-1.7	-1.9	-0.7	-0.7	-1.5	-1.7	-1.0
Tense / ‘highly strung’	0.9	1.5	6.7	-0.8	0.5	1.0	0.9	1.0	1.1	0.8	1.2	0.6	2.1	1.7	-0.3	-0.1	1.4	1.0	2.6
Medication: Seretide 50 evohaler	0.9	1.0	2.5	1.6	0.5	0.1	0.8	1.0	1.1	0.8	0.3	1.3	1.4	1.4	0.8	0.4	1.4	1.0	0.9
Smoking status: Current	0.9	1.5	4.3	-0.7	-2.1	-1.2	-1.3	0.3	1.6	-1.9	-2.0	-0.9	0.0	0.1	-0.8	-1.5	-0.7	-1.2	0.8
Financial situation satisfaction	0.9	1.1	3.5	-0.4	-1.7	-0.4	-0.9	-0.9	0.5	-1.6	-1.1	-0.2	-0.7	-0.7	-0.2	-1.1	-1.0	-1.9	-1.3
Hearing difficulty/problems: Yes	0.8	1.2	3.4	0.4	-1.3	-0.3	-1.8	-0.3	-0.9	-1.5	-0.5	0.2	-1.3	-1.1	-1.9	-1.4	-1.1	-1.1	0.2
Impedance of leg (right)	0.8	4.1	14.4	0.5	1.0	1.2	2.6	0.7	2.2	2.0	1.3	-0.6	3.8	3.1	0.7	0.5	2.8	1.8	3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.6	-1.1	-1.6	-0.3	-0.7	-0.2	0.1	-1.6	-1.2	-1.1	-0.5	-0.3	-1.3	-1.5	-0.9	-1.3	-0.1
Multivitamins +/- minerals	0.8	1.0	4.8	-1.1	0.3	-1.3	1.1	-2.2	-1.3	0.9	-0.1	-1.5	0.7	-0.4	-0.3	-0.8	-0.3	-0.4	-1.1
Impedance of leg (left)	0.8	4.0	13.0	0.5	1.3	1.1	2.7	0.9	1.9	2.1	1.4	-0.2	3.6	2.9	0.8	0.8	2.7	2.0	2.9
Hearing difficulty/problems with background noise	0.8	1.3	2.8	-0.8	-1.4	-0.2	-1.4	-0.3	-1.4	-1.7	-0.6	-0.3	-1.1	-1.4	-1.5	-1.3	-1.4	-1.0	-0.5
Qualifications: None of the above	0.8	1.7	4.8	1.6	-0.9	0.9	-0.7	-0.4	-1.6	-1.1	-0.8	-0.6	-2.2	-2.0	-0.4	-0.5	-1.8	-1.2	-2.0
Peak expiratory flow (PEF)	0.8	1.9	5.6	0.4	-0.3	-1.0	-1.8	-1.2	-2.2	-0.9	-1.0	-0.8	-2.2	-2.4	-0.0	0.0	-1.5	-1.3	-1.6
Medication: Paracetamol	0.8	1.4	3.7	-1.7	-0.8	-1.4	-0.8	-1.3	-1.9	-0.6	-0.8	-1.5	-0.8	-1.9	-0.3	-0.2	-1.4	-0.9	-0.7
Arm fat-free mass (right)	0.8	4.1	7.8	-0.6	-2.0	-1.0	-1.9	-1.3	-1.5	-2.5	-2.0	-0.5	-2.7	-2.4	-2.0	-1.9	-2.8	-2.4	-2.7
Health satisfaction	0.8	1.0	2.8	0.6	0.3	0.9	0.4	1.2	1.4	0.3	1.1	1.7	1.0	1.4	0.8	0.5	1.1	0.9	1.3
Arm predicted mass (right)	0.8	3.9	7.3	-0.8	-2.0	-1.0	-2.0	-1.3	-1.4	-2.4	-2.1	-0.5	-2.5	-2.3	-2.0	-2.0	-2.7	-2.4	-2.5
Comparative height size at age 10	0.8	4.4	10.9	-1.2	-3.0	-1.1	-2.4	-1.8	0.0	-3.2	-3.3	-0.4	-2.0	-1.3	-1.6	-2.1	-2.4	-2.5	-1.9
Back pain experienced in last month	0.8	1.1	5.2	-2.3	-0.3	-1.3	0.5	-1.7	-1.3	0.0	-0.5	-1.1	0.1	-1.5	-0.1	-0.3	-1.0	-0.9	-0.6
Mineral and other dietary supplements	0.8	1.0	3.7	-0.2	-1.2	0.3	-1.3	1.1	0.7	-1.7	-0.8	0.9	-0.9	-0.2	-1.9	-1.1	-0.7	-0.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.6	0.1	-0.7	-1.1	-0.4	-1.7	-1.9	-0.9	-1.0	-1.0	-2.0	-1.9	-0.3	-0.4	-1.4	-1.4	-2.1
Supplements: Fish oil (including cod liver oil)	0.8	1.1	6.8	0.0	0.2	-0.4	1.0	-2.1	-1.0	0.8	-0.5	-2.6	0.6	-0.6	1.2	0.1	-0.2	-0.4	-0.8
Schizophrenia vs Biploar Disorder	0.7	0.9	2.9	-0.8	-1.3	-1.7	-1.7	-0.9	-0.0	-1.0	-1.0	-0.4	-0.5	-0.5	-0.5	-1.1	-0.7	-1.1	0.2
Crohns Disease (2017)	0.7	1.5	6.0	0.2	1.2	1.4	0.7	2.4	1.1	1.1	1.7	1.1	1.5	1.1	0.0	0.8	0.9	1.3	1.4
LDL Cholesterol	0.7	1.1	3.3	-0.8	1.6	-0.1	0.8	0.5	-0.4	1.8	1.4	0.5	1.3	0.7	0.6	1.1	1.1	1.4	1.2
Severe depression (siblings)	0.7	0.7	3.2	-1.8	-1.0	-0.4	-1.7	0.0	0.4	-0.8	-0.9	0.3	-0.2	-0.0	-0.4	-0.2	-0.6	-0.5	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.5	-1.4	-1.1	-0.7	-0.7	-0.4	-0.4	-1.3	-0.8	-0.2	-1.0	-1.1	-0.8	-1.3	-1.6	-1.5	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	2.5	-1.4	-0.6	-0.2	-0.5	-1.2	-1.6	-0.3	-0.4	-1.1	-0.4	-1.1	-1.4	-0.9	-0.7	-0.7	0.4
Depression (self-reported)	0.7	0.9	3.5	0.1	1.2	0.7	0.5	1.2	0.1	0.8	1.4	1.9	0.7	0.3	1.0	1.2	0.6	0.7	0.7
Illnesses of mother	0.7	0.9	2.3	0.0	-1.4	-0.1	-0.5	-0.6	0.2	-1.3	-0.9	-1.5	-0.3	-0.2	-1.2	-1.5	-1.2	-1.2	-0.4
Pulse wave reflection index	0.7	0.8	3.5	-0.6	-1.3	0.1	-0.5	-1.0	0.5	-1.0	-0.7	0.3	-0.6	0.1	-1.4	-1.9	-0.7	-1.1	-0.6
Worry too long after embarrassment	0.7	1.1	6.2	2.3	0.5	0.7	0.9	-0.4	-0.1	0.7	0.9	-0.6	-0.1	-0.3	2.5	1.2	-0.1	0.0	-1.2
Qualifications: College or University degree	0.7	2.1	6.2	-2.3	0.6	0.5	0.3	1.3	1.6	0.8	0.7	1.0	1.5	1.9	0.9	1.2	2.0	1.7	2.5
Alcohol intake frequency.	0.7	1.7	4.2	-0.7	2.0	0.8	-0.2	1.6	0.5	1.2	2.0	1.3	-0.2	0.6	1.3	2.1	1.3	1.6	1.0
Age at last live birth	0.7	0.9	4.0	1.4	1.0	1.3	1.1	0.2	0.2	0.7	0.8	1.0	-0.4	0.1	2.0	1.2	0.2	0.8	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.4	-0.9	-0.4	-1.6	-0.6	-0.5	-1.3	-0.7	-0.2	0.2	-0.9	-1.2	-1.2	-0.8	-1.2	-0.8	-0.4
Ever had bowel cancer screening	0.7	0.8	2.7	1.2	0.5	0.1	0.0	-0.1	-1.5	0.1	-0.4	-0.1	-1.6	-1.4	0.4	0.8	-0.9	0.3	-1.4
Mother’s age at death	0.7	0.9	3.4	0.1	1.4	0.8	0.3	0.6	-0.1	0.9	1.1	1.2	-0.2	0.2	1.1	1.9	0.7	1.6	0.2
Medication: Atorvastatin	0.7	0.9	3.2	0.6	0.9	-0.0	1.8	0.4	0.4	1.2	1.1	0.2	1.5	1.0	0.8	0.6	1.1	1.0	0.2
Basal cell carcinoma (self-reported)	0.7	0.8	4.5	-2.1	-0.5	0.4	-0.4	-0.3	-1.4	-0.2	-0.8	-0.6	-0.4	-0.7	-1.6	-1.1	-0.8	-0.3	-0.3
Worry (Nagel 2018)	0.6	1.3	3.2	0.9	0.5	1.2	0.9	1.4	1.8	0.2	1.5	1.0	1.0	1.8	1.0	0.7	1.2	1.2	0.8
Blood White Count	0.6	4.2	12.9	1.1	2.7	1.4	0.7	3.6	0.9	2.1	2.6	1.2	2.0	1.9	-0.1	1.1	2.2	2.5	3.0
Cardiovascular Disease	0.6	1.8	5.3	0.6	1.9	0.5	2.3	1.9	-0.4	2.0	2.0	1.2	1.5	0.7	0.6	0.8	1.1	1.2	0.5
Average weekly spirits intake	0.6	0.7	1.9	-1.4	-0.8	0.1	-1.4	-0.3	-1.2	-0.7	-0.8	0.1	-0.6	-0.9	-1.2	-0.6	-0.9	-0.3	0.4
Medication for hormone replacement therapy	0.6	0.7	1.7	0.2	-1.3	-0.2	-1.0	0.1	1.3	-1.1	-1.0	0.7	-0.5	0.7	-0.8	-1.3	-0.5	-0.8	-0.3
Vitamin and mineral supplements	0.6	0.9	3.6	1.0	-0.3	1.1	-0.5	1.8	1.3	-0.7	0.1	1.9	-0.3	0.7	-0.4	0.1	0.3	0.3	1.1
Supplements: Glucosamine	0.6	0.7	3.0	1.7	0.9	0.2	0.3	-0.6	-1.7	0.5	0.6	0.0	-1.2	-0.8	0.4	0.7	-0.2	0.5	-1.0
Financial difficulties in last 2 years	0.6	0.8	6.5	-2.6	-0.7	-1.0	-0.2	-0.4	-0.6	-0.3	-0.4	-1.0	0.2	-0.6	-0.8	-0.9	-0.8	-1.0	-0.4
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.3	-1.5	0.6	0.6	-0.4	0.8	-0.8	0.9	0.3	1.1	0.4	-0.2	-0.0	1.2	0.5	1.2	1.5
Hip circumference	0.6	2.7	8.8	-0.6	-0.7	-1.7	-0.3	-1.5	-3.0	-0.6	-0.9	-0.5	-1.4	-2.2	-2.4	-1.9	-2.2	-1.5	-1.8
Noisy workplace	0.6	0.7	3.1	1.2	0.2	1.5	0.8	1.4	0.4	-0.2	0.6	1.8	-0.5	0.2	0.2	0.1	-0.3	0.4	-1.1
Birth weight of first child	0.6	1.1	4.9	0.3	0.5	0.5	-1.1	0.1	-0.5	-0.4	0.2	1.9	-2.2	-0.9	0.9	0.9	-0.9	0.1	-1.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.2	-0.5	-1.3	-0.2	-1.0	0.1	2.0	-1.3	-0.7	-0.4	0.7	1.2	-0.9	-1.0	0.1	-0.3	1.4
Wheeze or whistling in the chest in last year	0.6	1.1	4.2	0.6	-1.1	-1.2	0.1	-1.2	-0.6	-0.8	-1.6	-2.0	-0.6	-1.2	-0.0	-0.4	-1.2	-1.3	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	4.0	0.1	-0.0	-1.2	-0.3	-0.4	-2.0	-0.4	-0.4	-0.3	-0.8	-1.3	-0.7	-0.6	-1.2	-0.4	-0.6
Medication for pain relief, constipation, heartburn	0.6	1.1	5.2	2.3	0.4	0.7	0.3	0.6	1.9	-0.1	0.1	0.8	0.3	1.4	1.5	1.0	1.1	0.7	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.2	0.1	1.1	-0.3	0.6	-0.0	-1.4	1.5	1.1	-0.4	0.8	-0.6	1.1	1.3	0.5	0.6	0.5
Number of full sisters	0.6	0.8	1.7	0.5	-0.7	-0.5	-0.1	-1.2	-0.9	-0.4	-0.6	-1.1	-0.7	-1.2	0.1	-0.6	-1.0	-1.3	-1.3
Medication: Aspirin	0.6	0.9	3.6	-0.2	-1.3	-0.3	-1.4	-0.3	-0.1	-0.7	-0.8	0.0	-0.5	-0.5	-1.9	-1.6	-1.0	-1.0	0.1
Hypertension (Self-reported)	0.6	1.6	7.1	0.9	1.5	0.1	2.7	1.0	-0.2	2.2	1.4	0.5	2.1	0.9	-0.1	0.1	1.1	1.0	0.7
Illnesses of siblings: Diabetes	0.6	0.8	5.0	2.2	0.4	0.6	1.0	0.6	-1.3	0.1	0.3	-0.9	-0.1	-0.7	0.9	0.9	-0.0	0.3	-1.0
Friendships satisfaction	0.6	0.7	2.1	1.4	0.6	1.4	1.1	0.0	1.0	0.4	0.9	0.6	0.3	0.6	1.3	0.6	0.7	0.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	0.3	-0.9	0.7	-0.1	-0.1	-1.0	-1.1	-0.4	0.3	-1.0	-0.9	-0.7	-1.2	-1.1	-0.9	-1.3
Whole body water mass	0.6	3.3	7.7	-0.9	-1.7	-0.9	-2.2	-0.9	-1.1	-2.3	-1.8	0.2	-2.8	-2.1	-1.5	-1.5	-2.5	-2.1	-2.3
Medication: Lisinopril	0.6	0.7	3.1	1.1	0.7	0.7	1.8	-0.5	-0.9	1.1	0.4	-0.7	0.8	-0.9	0.9	0.6	-0.2	-0.1	-0.8
Number of operations (self-reported)	0.6	0.9	4.0	0.8	0.2	1.1	0.9	-0.0	-1.3	0.1	-0.0	-0.4	-1.8	-1.3	0.3	0.5	-0.8	-0.1	-2.0
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.0	1.3	-1.4	0.5	-0.4	-0.4	0.3	-1.3	-1.1	-0.3	-1.0	-0.3	-0.6	-1.0	-0.6	-1.1	-1.0
Bipolar Disorder (2018)	0.5	0.7	3.5	-1.3	-0.9	-0.8	0.3	-1.0	1.0	-1.0	-1.2	-1.9	0.6	0.3	0.2	-0.0	0.2	-0.5	0.1
Alzheimer’s Disease (in mother)	0.5	0.5	4.0	-2.0	0.0	-1.2	-0.5	-0.2	-0.8	-0.1	-0.7	0.4	-0.5	-0.3	-1.0	-0.2	-0.2	0.0	-0.1
Rheumatoid Arthritis	0.5	0.7	1.8	1.4	0.7	1.0	1.2	0.3	0.3	0.9	1.2	-0.2	0.7	0.2	1.2	0.7	0.5	0.4	-0.3
Hair Pigment	0.5	13.9	21.6	-2.2	-4.0	-3.4	-3.1	-4.3	-3.5	-3.6	-4.1	-2.5	-3.5	-3.9	-3.7	-4.3	-4.3	-4.7	-3.7
Sensitivity / hurt feelings	0.5	0.8	5.8	1.4	0.5	0.6	-0.0	-0.8	0.4	0.5	0.9	0.2	-0.3	-0.0	2.4	1.5	0.3	0.2	-0.6
Relative age of first facial hair	0.5	1.1	6.0	2.5	0.0	1.3	-0.3	1.0	0.8	-0.4	0.6	1.6	-1.5	0.2	0.5	0.7	-0.3	0.5	-1.0
Relative age voice broke	0.5	0.8	1.6	1.2	0.9	0.5	0.0	1.0	1.1	0.8	1.0	1.3	0.0	0.8	0.9	1.2	0.7	1.3	0.1
Diabetes (self-reported)	0.5	0.8	2.2	-0.3	-0.5	-0.3	-1.1	-0.6	-1.5	-0.6	-0.7	-0.9	-1.5	-1.4	-0.3	0.2	-1.1	-0.6	-0.8
Prospective memory result	0.5	0.6	2.7	-0.9	-0.8	0.1	-0.2	-0.4	-0.4	-0.7	-0.7	-0.8	-1.4	-0.5	-0.6	-0.5	-0.9	-0.7	-1.6
Loud music exposure frequency	0.5	0.6	6.1	-2.5	0.1	-1.2	-0.7	-0.7	-0.3	0.1	0.1	0.7	0.0	-0.1	0.2	-0.4	0.1	-0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.5	0.3	-1.0	-0.3	-0.9	-1.2	-0.2	-1.1	-1.2	-0.1	-1.1	-0.7	-0.3	-0.5	-0.5	-1.0	-0.7
Leg fat percentage (right)	0.5	1.7	6.7	2.3	1.1	0.4	2.6	0.3	-1.6	1.9	1.5	-0.8	1.9	0.1	-0.9	-0.6	0.4	0.4	0.1
Shortness of breath walking on level ground	0.5	0.6	3.1	0.2	-0.9	-0.1	-0.4	0.9	0.8	-0.8	-0.7	0.9	0.5	0.7	-1.8	-1.4	-0.0	-0.2	0.5
Eye problems/disorders: None of the above	0.5	0.6	2.5	-0.3	-0.3	0.1	0.6	-1.1	-0.7	-0.3	-0.7	-1.4	-0.4	-0.8	1.0	0.4	-0.2	-0.7	-1.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.7	-0.8	0.4	-1.3	1.2	-0.5	-1.3	0.4	0.3	-1.1	0.9	-0.3	-0.4	-0.7	0.0	-0.0	0.1
Had major operations	0.5	0.6	2.4	-1.5	0.5	0.3	1.0	0.5	0.5	0.8	0.2	1.0	0.4	-0.0	1.4	1.1	0.4	0.4	0.0
Illnesses of father: Heart disease	0.5	0.7	3.5	-0.2	0.9	-0.0	0.3	0.8	0.8	0.9	1.1	1.9	-0.0	0.9	0.5	0.5	1.0	0.8	0.5
Whole body fat-free mass	0.5	2.9	7.2	-0.7	-1.5	-0.7	-2.1	-0.7	-0.9	-2.2	-1.7	0.4	-2.7	-1.9	-1.4	-1.3	-2.3	-1.9	-2.2
Average weekly red wine intake	0.5	0.7	1.8	0.2	0.7	0.2	1.0	0.9	0.6	0.9	0.9	0.6	1.3	1.2	-0.2	-0.1	1.1	1.0	0.8
Long-standing illness, disability or infirmity	0.5	0.8	1.7	0.1	-1.2	-0.6	0.3	-0.9	-0.8	-0.9	-0.6	0.2	-0.5	-1.0	-0.6	-1.3	-1.3	-1.3	-0.9
Diabetes diagnosed by doctor	0.5	0.8	2.6	-0.3	-0.7	-0.1	-1.3	-0.3	-1.5	-0.9	-0.7	-0.2	-1.6	-1.4	-1.1	-0.3	-1.2	-0.6	-0.4
Medication for cholesterol	0.5	0.8	2.4	-1.0	0.1	0.7	-0.9	-0.8	-1.0	-0.6	-0.2	-0.4	-1.2	-1.6	1.3	1.4	-0.3	-0.1	-0.7
Osteoporosis (self-reported)	0.5	0.7	1.8	-0.9	-0.5	-1.2	-0.7	-1.1	-0.5	-0.8	-1.4	-1.0	-0.9	-0.7	0.4	0.3	-0.5	-0.5	-0.8
Leg predicted mass (right)	0.5	2.5	7.7	-0.7	-1.2	-0.7	-2.3	-0.4	-0.8	-2.0	-1.4	0.9	-2.8	-1.9	-1.1	-1.0	-2.2	-1.6	-1.9
Commuting to job workplace: Public transport	0.5	0.6	1.7	0.3	0.3	0.4	0.5	0.7	1.0	0.5	0.8	1.1	1.0	0.4	0.3	0.8	0.7	0.7	1.3
Medication: Blood pressure	0.5	1.0	3.1	0.8	-0.4	-1.0	1.1	0.8	0.6	0.3	0.2	1.2	1.1	1.3	-1.7	-1.8	0.4	0.2	0.8
Leg fat percentage (left)	0.5	1.7	6.8	2.2	1.2	0.1	2.6	0.4	-2.0	2.0	1.5	-0.5	1.6	-0.3	-0.8	-0.3	0.3	0.5	-0.1
Myopia	0.5	0.8	4.0	-2.0	-0.8	-1.2	-0.9	-0.6	-0.4	-0.8	-0.9	0.3	-0.7	-0.5	-0.6	-0.6	-0.8	-0.8	-0.7
Cholesterol lowering medication	0.5	0.7	5.2	-0.7	-0.2	-0.6	-0.3	-0.1	-1.3	-0.1	-0.1	0.1	-0.1	-0.6	-2.3	-1.5	-0.9	-0.4	0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	5.7	-2.4	0.1	-1.0	0.6	-0.8	0.0	0.3	-0.2	-0.0	0.7	0.1	-0.9	-0.8	0.0	-0.2	0.2
Supplements: Calcium	0.5	0.5	1.6	-0.1	1.2	0.8	0.2	0.3	-0.7	0.8	1.2	0.6	0.1	-0.1	0.8	1.2	0.4	0.9	0.5
Arm predicted mass (left)	0.5	2.4	4.9	-0.4	-1.2	-0.6	-1.6	-0.9	-1.5	-1.7	-1.4	-0.2	-2.2	-2.1	-1.5	-1.2	-2.2	-1.8	-2.1
Crohns Disease (2012)	0.4	0.7	2.1	-0.1	-0.9	1.1	-0.5	1.2	0.8	-1.0	-0.1	1.3	-0.4	0.4	-1.4	-1.2	-0.3	-0.3	0.0
Primary Biliary Cirrhosis	0.4	0.6	2.8	-0.1	-0.5	0.1	1.2	-0.4	0.8	-0.0	0.0	-0.5	1.7	0.9	-1.2	-1.1	0.3	0.0	0.8
Triglycerides	0.4	0.7	2.3	1.5	1.1	-0.7	1.1	0.6	-1.4	1.1	0.9	-0.6	0.3	-0.5	-0.3	0.3	-0.0	0.6	-0.6
Ulcerative Colitis	0.4	0.6	2.6	-0.1	0.9	-0.4	1.1	0.4	0.5	1.0	0.9	-0.4	1.6	0.5	0.2	0.4	1.0	0.3	1.1
Diabetes (mother)	0.4	0.6	1.3	0.0	-0.5	-1.1	-0.1	-0.0	-1.0	-0.4	-0.8	-0.7	-0.2	-1.2	-1.0	-0.7	-0.9	-0.9	-0.9
Leg fat-free mass (left)	0.4	2.1	5.6	-0.4	-1.3	-0.6	-2.1	-0.5	-0.7	-1.9	-1.3	0.5	-2.4	-1.6	-1.3	-1.2	-2.0	-1.6	-1.7
Taking other prescription medications	0.4	0.6	2.0	1.2	0.3	1.4	0.8	0.4	0.1	0.3	1.3	1.4	0.1	-0.1	0.7	0.4	0.3	0.2	-0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.4	1.5	-0.1	1.5	1.2	0.6	0.6	0.0	0.1	0.5	-0.2	0.3	0.0	0.0	0.0	0.3	-1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.2	-0.1	0.4	1.1	0.7	0.7	0.4	0.3	0.4	-0.9	0.6	0.6	0.9	0.8	0.6	0.9	0.7
High blood pressure	0.4	1.0	5.2	0.1	1.1	-0.5	2.3	0.3	-1.1	1.9	0.9	-0.0	1.6	0.2	-0.8	-0.6	0.3	0.5	0.5
Sitting height	0.4	3.0	13.0	-0.2	1.0	1.6	-0.7	2.4	2.8	-0.1	0.9	3.6	0.4	2.4	0.7	1.0	1.6	1.9	1.9
Leg predicted mass (left)	0.4	2.0	5.5	-0.4	-1.1	-0.6	-2.0	-0.4	-0.7	-1.8	-1.2	0.6	-2.4	-1.6	-1.2	-1.1	-2.0	-1.5	-1.7
Mouth/teeth dental problems	0.4	0.6	1.8	-0.4	1.0	-0.1	0.7	0.8	0.6	1.4	0.4	-0.3	1.3	0.8	0.1	0.3	1.0	0.9	0.6
Allergy	0.4	0.9	2.8	-0.9	0.6	0.3	0.5	0.7	1.4	0.7	0.6	0.6	1.5	1.7	-0.3	-0.5	1.1	0.7	1.6
Trunk fat-free mass	0.4	2.5	6.5	-0.8	-1.5	-0.6	-1.9	-0.8	-0.7	-2.2	-1.7	0.3	-2.5	-1.7	-1.2	-1.2	-2.1	-1.7	-2.0
Time employed in main current job	0.4	0.5	1.5	-0.8	-0.7	-1.2	-0.5	-0.6	1.2	-0.9	-0.9	0.4	-0.4	0.7	-0.6	-0.6	0.2	0.1	0.1
Father’s age at death	0.4	0.5	1.5	-0.8	1.1	-0.8	0.2	0.5	-0.8	1.0	0.7	0.3	0.2	0.0	0.5	1.2	0.5	1.0	0.5
Worrier / anxious feelings	0.4	0.8	3.5	1.8	0.6	1.0	1.9	0.5	0.6	0.5	1.0	-0.3	0.7	1.0	0.6	0.1	0.7	0.8	-0.4
Number of live births	0.4	0.6	1.9	0.3	-0.7	-0.6	-0.3	-1.0	-0.3	-0.3	-0.9	-1.4	-0.4	-1.0	-0.2	-0.4	-1.1	-1.0	-0.9
Medication: Lansoprazole	0.4	0.4	1.7	-0.6	-0.9	-0.2	-0.6	-0.7	0.1	-0.6	-0.6	-0.9	-0.2	0.1	-1.1	-1.3	-0.5	-0.5	0.3
Lung cancer (father)	0.4	0.4	1.1	0.4	-0.6	0.7	-1.1	1.0	1.0	-1.1	0.1	0.7	-0.6	0.3	-0.3	-0.5	-0.2	-0.4	0.7
Trunk predicted mass	0.4	2.5	6.4	-0.8	-1.5	-0.6	-1.9	-0.8	-0.8	-2.2	-1.7	0.3	-2.5	-1.8	-1.2	-1.2	-2.1	-1.8	-2.1
Length of working week for main job	0.4	0.4	2.8	-0.6	-0.1	0.1	0.1	0.6	1.7	-0.2	-0.3	0.2	0.3	1.2	0.6	0.4	0.6	0.3	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.6	-1.9	-0.0	-0.1	0.3	0.6	-0.5	0.4	0.2	-0.7	1.0	0.3	-0.8	-0.7	0.1	0.1	1.3
Headache pain in last month	0.4	0.7	5.6	-2.4	-0.0	-0.2	0.1	0.1	0.8	-0.1	0.7	0.3	1.1	0.8	-0.1	-0.3	0.7	0.4	1.1
Medication: Blood pressure	0.4	0.7	3.6	-1.0	0.9	-0.9	0.8	-0.5	-1.9	1.2	0.3	0.6	-0.3	-1.0	0.1	0.3	-0.2	-0.0	-0.9
Medication: Omeprazole	0.4	0.5	4.4	-2.1	-0.0	-0.9	0.8	-0.3	0.7	0.1	-0.2	-0.1	0.9	0.6	-0.6	-0.4	0.6	0.1	0.5
Suffer from ‘nerves’	0.4	0.6	1.9	-0.6	-0.7	-0.1	-1.1	-0.3	-0.3	-1.3	0.1	1.1	-1.4	-0.6	-0.2	-0.5	-0.7	-0.8	-0.7
Leg fat-free mass (right)	0.4	2.2	7.0	-0.5	-1.1	-0.6	-2.1	-0.3	-0.8	-1.8	-1.2	0.9	-2.6	-1.8	-1.0	-0.8	-2.1	-1.5	-1.9
Commuting to job workplace: Walk	0.4	0.4	2.2	1.0	0.8	0.3	-0.2	1.5	-0.7	0.0	0.7	0.2	-0.2	-0.2	0.3	0.6	-0.3	0.8	0.3
Eye problems/disorders: Cataract	0.4	0.5	4.3	-0.0	-0.2	-0.9	-0.6	0.1	-0.4	-0.0	0.1	-0.4	-0.5	0.1	-2.1	-1.3	-0.5	-0.1	0.2
Guilty feelings	0.4	0.7	2.5	0.5	-0.5	0.0	-0.2	-0.3	0.2	-0.8	-0.7	-0.8	-1.4	-0.9	0.8	-0.1	-1.2	-0.9	-1.6
Ever taken oral contraceptive pill	0.4	0.4	1.4	-0.4	0.3	-1.1	0.3	-0.4	-0.2	0.8	-0.3	-1.1	1.2	-0.1	0.7	0.4	0.4	-0.3	1.1
Hearing aid user	0.4	0.5	2.8	1.7	-0.2	-0.4	1.0	0.2	-0.6	-0.5	-0.3	0.6	-0.5	-0.5	-0.6	-0.1	-0.5	0.1	-1.3
Pain type(s) experienced in last month: Hip pain	0.4	0.6	2.6	-1.1	0.0	0.1	-0.1	-0.3	-1.6	0.2	0.2	0.1	-0.7	-1.3	0.2	-0.0	-1.3	-0.6	-0.9
High cholesterol (Self-reported)	0.4	0.8	2.2	1.1	1.5	0.6	1.3	0.9	-1.2	1.2	1.2	0.5	-0.0	-0.2	-0.4	0.2	0.1	0.8	-0.8
Medication: Paracetamol	0.4	0.7	1.2	-0.9	-1.0	-1.1	-0.9	-0.8	-1.0	-0.9	-1.0	-1.1	-0.3	-1.0	-0.3	-0.5	-0.7	-0.7	-0.0
Basal metabolic rate	0.4	2.0	4.8	-0.5	-1.1	-0.6	-1.7	-0.5	-1.1	-1.7	-1.3	0.4	-2.2	-1.8	-1.3	-1.2	-2.0	-1.6	-1.8
Arm fat-free mass (left)	0.4	2.2	4.8	-0.5	-1.1	-0.7	-1.7	-0.7	-1.4	-1.7	-1.4	-0.1	-2.2	-2.0	-1.5	-1.1	-2.1	-1.7	-2.0
Heart disease (siblings)	0.4	0.5	3.9	-0.2	0.7	2.0	1.1	0.2	-1.0	0.7	0.8	-0.3	0.6	-0.3	-0.5	-0.2	-0.3	0.1	-0.1
Breast Cancer	0.3	0.8	3.3	-0.3	-0.5	-1.1	-1.1	-0.4	-0.8	-0.9	-0.7	0.1	-1.8	-0.9	-0.9	-0.8	-1.1	-0.6	-1.0
Systolic Blood Pressure	0.3	1.4	5.2	-0.6	0.9	-1.0	2.2	-0.1	-0.3	1.4	0.3	-2.3	2.2	0.7	0.0	0.1	1.0	0.5	0.6
Allergy or Eczema	0.3	0.9	3.1	-0.0	1.2	1.6	0.4	1.1	-0.2	1.1	0.9	0.7	0.1	0.1	1.0	1.8	0.6	1.3	0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.9	0.0	-0.6	-0.9	-0.3	-0.4	-0.9	-0.7	-0.8	-0.6	-0.9	-0.9	-0.8	-0.3	-0.8	-0.7	-0.8
Systolic blood pressure, automated reading	0.3	1.0	6.1	-0.7	0.5	-1.3	1.0	-0.6	-0.4	1.3	0.2	-2.5	1.7	0.4	0.0	0.1	0.6	0.2	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.8	-0.1	0.7	0.7	-0.2	-0.1	0.1	0.7	0.7	0.1	0.7	0.5	0.4	0.6	0.7	0.5	1.3
Trunk fat percentage	0.3	1.2	3.2	1.7	1.4	0.2	1.3	0.8	-0.8	1.8	1.5	0.4	1.3	0.5	-0.8	-0.1	0.7	0.9	1.1
Fed-up feelings	0.3	0.6	2.2	0.6	-0.8	0.3	0.6	0.2	1.5	-0.7	-0.6	-1.3	1.0	0.9	-0.2	-0.9	-0.1	-0.5	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.3	0.1	0.9	1.2	0.4	0.8	-0.7	0.5	0.7	0.7	-0.7	-0.4	0.7	1.5	0.2	0.9	-0.4
Medication: Atenolol	0.3	0.4	1.2	0.1	0.7	-0.9	0.7	0.1	-0.8	1.1	0.8	0.1	0.6	-0.3	-0.8	-0.2	0.4	0.4	0.5
Neuroticism score	0.3	0.7	2.3	1.5	-0.0	1.5	0.9	0.5	1.4	-0.1	0.7	0.2	0.5	0.8	1.3	0.5	0.4	0.3	-0.2
Arm fat percentage (right)	0.3	1.2	3.7	1.4	1.6	-0.5	1.3	0.6	-1.8	1.9	1.6	0.1	1.1	-0.3	-0.4	0.2	0.4	0.8	0.8
Glaucoma (self-reported)	0.3	0.3	1.0	-0.0	-0.4	0.5	-0.8	0.5	0.7	-0.9	-0.1	-0.2	0.1	0.3	-0.9	-0.5	-0.3	-0.1	1.0
Body fat percentage	0.3	1.1	3.2	1.8	1.2	-0.1	1.6	0.4	-1.4	1.8	1.4	-0.1	1.4	0.0	-1.0	-0.4	0.3	0.5	0.6
Exposure to tobacco smoke outside home	0.3	0.3	0.8	0.0	-0.9	0.2	-0.1	-0.2	-0.0	-0.8	-0.7	-0.7	-0.6	-0.2	-0.9	-0.6	-0.4	-0.9	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.3	-0.2	0.2	1.1	0.5	-0.2	0.2	0.2	0.1	0.8	-0.0	-1.3	-1.2	-0.5	-0.3	0.2
Neck or shoulder pain in last month	0.3	0.5	1.6	-0.5	-1.3	-0.9	-1.2	-0.3	0.4	-0.8	-0.9	-0.1	-0.2	-0.3	-0.2	-0.5	-0.6	-1.0	0.3
Medication: Allopurinol	0.3	0.4	2.9	-1.7	0.8	-0.0	0.4	0.4	-0.4	0.8	0.6	0.5	0.6	0.0	0.1	0.0	0.5	0.6	0.6
Chest pain or discomfort	0.3	0.5	1.6	0.2	-1.1	-0.4	-0.3	-0.2	0.3	-0.8	-1.1	-0.5	0.4	0.1	-1.0	-1.3	-0.4	-0.8	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.9	1.2	0.4	0.3	0.7	0.8	1.4	-0.1	0.0	1.4	-0.1	0.8	0.2	0.1	0.5	0.3	-0.8
Mood swings	0.3	0.5	2.8	-0.0	-0.9	1.1	-0.1	0.2	1.7	-0.9	-0.3	0.1	0.4	1.0	0.9	-0.3	-0.0	-0.3	0.1
Qualifications: nursing, teaching	0.3	0.5	3.2	-0.2	0.6	0.0	-1.0	0.6	0.4	0.1	0.5	1.8	-1.0	0.9	-0.4	-0.0	0.8	0.6	0.4
Breast cancer (self-reported)	0.3	0.4	0.8	-0.7	0.9	-0.3	0.4	0.1	-0.6	0.9	0.7	-0.7	0.5	0.1	0.1	0.5	0.6	0.6	0.9
Eye problems/disorders: Glaucoma	0.3	0.3	1.1	-0.8	-0.3	-0.3	-0.9	-0.3	-0.1	-0.5	-0.4	-0.3	-0.2	-0.6	-0.6	-0.4	-0.6	-0.3	1.0
Medication: Bendroflumethiazide	0.3	0.4	1.8	0.0	-0.5	-1.2	0.5	-0.8	-0.7	-0.3	-0.2	-0.1	0.3	-0.2	-0.4	-1.3	-0.2	-0.7	-0.5
Alcohol drinker status: Previous	0.3	0.3	1.5	-0.9	0.2	-1.1	-0.8	-0.2	-0.1	0.1	-0.4	-0.1	0.2	-0.0	-0.3	-0.3	0.1	0.1	1.2
Depressed Affect (Nagel 2018)	0.2	0.5	1.8	-0.3	-1.3	0.2	-0.3	-0.1	0.9	-1.3	-0.9	-0.4	0.3	0.3	-0.5	-1.1	-0.7	-0.7	-0.1
Neuroticism (Nagel 2018)	0.2	0.5	2.8	0.5	-0.3	0.9	0.6	0.5	1.7	-0.3	0.5	0.5	0.5	1.0	1.1	0.2	0.3	0.2	-0.1
Alzheimer’s Disease (in father)	0.2	0.3	2.9	-1.7	-0.1	-0.1	-0.1	-0.4	-0.4	0.1	-0.5	-0.7	0.1	-0.3	-0.1	0.2	-0.3	-0.0	-0.1
Neuroticism (2016)	0.2	0.4	1.0	0.8	0.3	0.2	0.2	0.7	0.7	0.1	0.9	1.0	0.6	0.8	-0.3	-0.3	0.3	0.4	0.7
Blood Eosinophil Count	0.2	1.4	4.0	1.9	0.8	1.6	1.1	1.5	1.2	0.7	1.8	2.0	0.3	1.3	-0.2	-0.3	0.7	0.7	-0.4
Blood Red Count	0.2	1.8	6.5	1.5	2.5	1.2	1.1	0.8	-1.0	2.0	1.8	1.1	-0.4	0.0	0.9	1.8	0.5	1.5	-0.6
BMI	0.2	1.2	6.4	0.9	1.2	-0.5	0.3	-0.1	-2.5	0.8	0.9	0.8	-0.9	-1.7	-0.4	-0.1	-1.2	-0.4	-1.8
Height	0.2	3.2	20.2	-0.6	-1.3	1.5	-1.0	0.5	4.5	-1.7	-1.0	2.6	-0.6	3.2	-0.9	-0.9	1.0	0.5	1.2
Neuroticism	0.2	0.4	1.6	1.1	-0.4	0.9	0.9	0.3	1.3	-0.2	0.3	0.4	0.7	0.9	0.8	-0.1	0.3	-0.1	-0.3
Ever had hysterectomy (womb removed)	0.2	0.3	2.2	1.5	-0.1	0.1	-0.0	0.8	0.3	0.1	0.5	-0.2	0.3	0.1	-0.9	-0.3	0.2	0.0	0.5
Angina	0.2	0.2	2.2	1.5	-0.4	0.6	0.2	0.3	0.5	-0.0	-0.2	0.1	0.3	0.1	-0.1	-0.2	0.2	-0.3	0.3
Supplements: Zinc	0.2	0.3	0.8	0.4	0.9	0.2	0.7	0.3	-0.1	0.8	0.8	0.3	0.4	0.3	0.5	0.2	0.4	0.6	-0.3
Body mass index (BMI)	0.2	1.0	6.0	1.0	0.2	-0.7	0.2	-0.2	-2.4	0.3	0.3	-0.1	-0.5	-1.6	-1.2	-0.8	-1.1	-0.7	-0.9
Waist circumference	0.2	0.7	4.5	0.4	0.6	0.5	0.9	-0.0	-2.1	0.7	0.7	-0.1	-0.5	-1.0	-1.5	-0.6	-0.6	-0.1	-0.7
Number of incorrect matches in round	0.2	0.3	1.4	-0.3	0.3	0.9	0.9	0.2	-0.1	0.3	0.3	-0.2	0.0	0.8	-1.2	-0.5	0.2	0.3	0.5
Medication: Simvastatin	0.2	0.3	1.5	1.2	0.0	0.3	0.6	1.0	-0.2	-0.0	-0.0	1.0	-0.4	-0.1	-0.9	-0.5	-0.2	-0.1	-0.6
Alcohol intake versus 10 years previously	0.2	0.3	3.2	-1.8	-0.3	-0.9	-0.0	-0.2	-0.3	-0.1	-0.3	0.1	0.1	-0.1	-0.7	-0.3	-0.2	-0.5	0.2
Hair/balding pattern: Pattern 3	0.2	0.4	1.5	1.0	-0.3	-0.3	0.4	-1.2	-0.2	0.0	-0.2	-1.1	0.3	-0.1	-0.6	-0.8	-0.3	-0.5	-0.5
Medication: Cholesterol lowering	0.2	0.3	0.8	0.9	0.7	0.7	0.9	0.3	-0.2	0.8	0.2	0.6	0.1	0.0	0.8	0.5	0.4	0.3	-0.8
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.5	-0.5	-0.3	-0.7	0.2	-0.4	-0.6	0.1	-0.2	-0.6	0.7	-0.4	-0.4	-0.5	-0.6	-0.5	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	0.8	-0.5	0.8	-0.0	-0.2	0.2	0.6	0.5	0.2	0.4	0.0	0.3	0.8	0.9	0.4	0.6	-0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.7	0.4	-0.3	0.7	-0.2	0.2	0.6	-0.4	0.0	1.3	0.1	0.4	-0.1	0.1	0.3	0.1	-0.1
Gout (self-reported)	0.2	0.3	2.1	-1.4	-0.0	-0.3	0.2	-0.6	-0.3	0.1	-0.2	-0.3	0.5	-0.5	-0.2	-0.5	0.2	-0.4	0.6
Birth weight	0.2	0.4	1.9	-0.5	0.2	1.0	-0.1	0.9	0.5	-0.4	-0.2	1.0	-0.6	0.3	1.4	0.6	0.2	0.3	-0.4
Number of children fathered	0.2	0.2	0.5	0.3	-0.1	-0.7	-0.7	-0.7	0.3	-0.2	-0.5	-0.6	0.1	-0.0	0.6	0.1	0.2	-0.5	0.1
Angina (self-reported)	0.2	0.2	2.6	1.6	-0.2	0.6	0.0	0.4	0.3	0.0	-0.2	0.3	-0.0	-0.1	-0.1	-0.0	0.0	-0.2	0.1
Medication: Ibuprofen	0.2	0.2	0.7	-0.4	-0.6	-0.1	-0.5	-0.8	-0.2	-0.4	-0.4	-0.4	-0.2	-0.3	-0.8	-0.6	-0.1	-0.6	0.5
Heart disease (mother)	0.2	0.2	1.0	-1.0	0.4	0.6	0.4	0.2	-0.1	0.6	-0.0	0.8	0.2	0.2	-0.6	-0.2	0.1	0.4	-0.4
Leg fat mass (right)	0.2	0.7	2.7	1.6	0.2	-0.2	1.3	-0.0	-1.4	0.8	0.5	-0.5	0.8	-0.5	-1.3	-1.0	-0.4	-0.3	-0.4
Overall health rating	0.2	0.5	2.3	0.9	-0.7	-0.2	1.5	0.2	0.9	-0.2	-0.3	-0.5	1.4	0.5	0.5	-0.5	0.0	-0.4	0.3
Leg pain on walking	0.2	0.3	2.2	0.4	-0.6	0.2	0.1	0.2	0.6	-0.5	0.3	1.5	-0.1	0.4	-0.5	-0.8	-0.5	-0.1	0.1
Supplements: Vitamin C	0.2	0.3	0.9	-0.6	0.8	-0.1	0.2	-0.2	-0.6	0.6	0.3	-0.1	-0.6	-0.5	0.8	1.0	-0.1	0.3	-0.6
Arm fat percentage (left)	0.2	0.8	3.5	1.1	1.0	-0.8	0.9	0.3	-1.9	1.3	1.1	0.0	0.7	-0.6	-1.0	-0.4	-0.1	0.2	0.4
Medication: Aspirin	0.2	0.3	1.3	-0.1	-0.6	-0.0	-1.1	0.1	0.4	-0.1	-0.2	0.3	-0.1	0.0	-1.1	-0.8	-0.3	-0.3	0.8
Medication: Gliclazide	0.2	0.2	0.9	-0.6	-0.2	-0.0	-0.6	-0.1	-0.8	-0.5	-0.0	0.5	-0.6	-0.5	-1.0	-0.4	-0.6	-0.1	0.1
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	0.6	0.1	0.5	0.7	0.1	-1.1	0.4	0.5	0.5	-0.3	-0.9	-0.1	0.2	-0.5	-0.2	-0.3
Miserableness	0.2	0.4	1.4	0.4	-0.2	0.7	0.8	0.7	1.2	-0.3	-0.0	-0.0	1.2	1.0	0.8	0.2	0.6	0.4	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	3.3	-0.5	-0.5	0.0	-1.8	-0.4	0.6	-1.3	-0.6	-0.2	-1.1	-0.3	0.8	0.7	-0.2	-0.2	-0.3
Leg fat mass (left)	0.2	0.8	3.1	1.6	0.3	-0.4	1.2	-0.1	-1.8	0.7	0.5	-0.5	0.6	-0.8	-1.3	-0.9	-0.6	-0.4	-0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.7	0.2	-0.2	-0.8	0.3	-0.0	-0.3	-0.2	-0.0	0.4	-0.3	-0.5	0.1	0.1	-0.2	-0.1	-0.9
Tanning	0.1	0.8	3.4	0.3	-1.5	-0.1	-0.4	-0.6	1.8	-1.2	-1.2	-0.5	0.2	0.6	-0.3	-1.0	-0.4	-0.9	-0.2
Number of treatments/medications taken	0.1	0.2	0.7	0.6	-0.1	-0.1	0.9	-0.2	-0.3	0.3	0.6	0.0	0.5	-0.2	-0.3	-0.5	0.0	-0.3	0.0
Medication: Metformin	0.1	0.2	0.8	0.2	0.2	0.9	0.2	0.1	-0.5	-0.0	0.3	0.3	-0.8	-0.7	-0.2	0.2	-0.3	-0.0	-0.4
Pack years adult smoking proportion	0.1	0.2	0.5	-0.3	-0.7	-0.4	0.4	-0.1	0.5	-0.3	-0.7	-0.1	0.2	-0.0	-0.5	-0.7	0.1	-0.4	0.1
Serious illness, injury or assault to yourself	0.1	0.2	1.0	-0.6	0.2	-1.0	0.2	0.2	-0.1	0.1	0.2	0.7	0.7	0.1	-0.1	-0.4	0.3	-0.0	0.4
Trunk fat mass	0.1	0.6	2.4	1.6	0.8	0.1	0.8	0.5	-1.0	1.0	0.9	0.6	0.5	-0.0	-1.0	-0.5	0.0	0.3	0.3
Had other major operations	0.1	0.2	0.8	0.8	0.0	0.1	0.1	-0.1	-0.4	-0.1	0.1	-0.9	-0.4	-0.4	0.1	0.2	-0.1	-0.3	-0.7
Weight	0.1	0.6	1.7	0.5	-0.2	-0.2	-0.2	-0.2	-1.3	-0.4	-0.2	0.5	-0.8	-1.1	-1.3	-1.0	-1.1	-0.8	-1.0
Falls in the last year	0.1	0.2	0.4	0.0	-0.3	0.5	-0.4	-0.1	0.1	-0.5	-0.5	0.3	-0.7	-0.3	0.5	0.3	-0.1	-0.7	-0.6
Arm fat mass (right)	0.1	0.6	3.7	1.0	0.8	-0.6	0.5	0.1	-1.9	0.9	0.8	0.0	0.1	-1.0	-0.8	-0.2	-0.5	-0.1	-0.1
Standing height	0.1	1.2	6.4	-0.7	-1.0	0.7	-1.1	0.1	2.5	-1.6	-1.2	1.7	-0.9	1.2	-0.3	-0.4	-0.2	-0.2	-0.1
Whole body fat mass	0.1	0.6	2.2	1.5	0.7	-0.0	0.8	0.2	-1.4	0.9	0.8	0.1	0.4	-0.5	-1.2	-0.6	-0.3	-0.0	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.4	0.6	-0.5	0.2	0.0	0.2	0.6	-0.6	0.6	1.2	-0.1	0.6	0.1	-0.5	0.2	0.1	0.2
Arm fat mass (left)	0.1	0.5	3.2	0.9	0.7	-0.6	0.4	0.3	-1.8	0.8	0.8	0.5	0.0	-0.9	-0.9	-0.4	-0.5	-0.0	-0.1
Pack years of smoking	0.1	0.2	0.6	0.5	-0.7	0.2	0.5	-0.0	0.8	-0.3	-0.5	0.1	-0.0	0.3	-0.2	-0.6	0.2	-0.2	-0.1

Hub : Genes

MSH6

Models

Trait associations