Best TWAS P=2.36e-07 · Best GWAS P=3.24e-07 conditioned to 0.141
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | NPC1 | 0.26 | 0.07 | enet | 31 | 0.11 | 3.7e-09 | 4.8 | -5.2 | 2.4e-07 | -0.83 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | NPC1 | 0.16 | 0.10 | lasso | 3 | 0.10 | 3.7e-04 | 4.9 | -5.1 | 2.9e-07 | -0.95 | 0.01 | 0.88 | FALSE |