[Hub]/) : Traits : Past tobacco smoking :

chr3:84,317,575-86,808,226

Best TWAS P=8.7e-17 · Best GWAS P=2.12e-17 conditioned to 0.0393

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose CADM2 0.05 0.06 lasso 10 0.06 1.3e-09 -6.9 -6.6 3.3e-11 0.67 0.95 0.05 FALSE
2 The Cancer Genome Atlas Brain Lower Grade Glioma CADM2 0.06 0.00 blup 339 0.00 2.7e-01 5.6 6.8 7.3e-12 -0.46 0.07 0.06 FALSE
3 The Cancer Genome Atlas Lung Adenocarcinoma CADM2 0.08 0.04 lasso 4 0.05 2.1e-06 -8.1 -8.3 8.7e-17 0.93 0.03 0.96 TRUE
4 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CADM2 0.05 0.03 lasso 3 0.04 5.0e-05 -8.1 -8.0 1.7e-15 0.94 0.05 0.95 FALSE
5 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CADM2 0.14 0.05 blup 339 0.09 2.7e-04 -8.3 -6.2 6.0e-10 0.84 0.06 0.76 FALSE
6 The Cancer Genome Atlas Thyroid Carcinoma CADM2 0.05 0.00 blup 339 0.02 3.2e-03 -2.6 -6.4 1.8e-10 0.67 0.04 0.51 FALSE