TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Past tobacco smoking
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chr4:57,080,198-58,531,645
Best TWAS P=3.13e-08 · Best GWAS P=2.3e-08 conditioned to 0.0974
57M
57.2M
57.4M
57.6M
57.8M
58M
58.2M
58.4M
58.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
REST
0.15
0.08
enet
12
0.04
7.4e-03
5.4
5.5
3.1e-08
0.85
0.02
0.97
TRUE
1
GTEx
Nerve Tibial
NOA1
0.08
0.02
enet
5
0.02
1.5e-02
4.4
5.5
4.8e-08
0.61
0.18
0.46
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
C4orf14
0.07
0.05
blup
57
0.06
3.2e-06
-3.6
5.3
1.1e-07
0.51
0.40
0.50
FALSE
3
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
C4orf14
0.13
0.11
lasso
2
0.10
6.2e-05
5.1
5.3
1.3e-07
0.78
0.02
0.87
FALSE