Best TWAS P=3.13e-08 · Best GWAS P=2.3e-08 conditioned to 0.0974
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | NOA1 | 0.08 | 0.02 | enet | 5 | 0.02 | 1.5e-02 | 4.4 | 5.5 | 4.8e-08 | 0.61 | 0.18 | 0.46 | FALSE |
| 2 | GTEx | Testis | REST | 0.15 | 0.08 | enet | 12 | 0.04 | 7.4e-03 | 5.4 | 5.5 | 3.1e-08 | 0.85 | 0.02 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C4orf14 | 0.13 | 0.11 | lasso | 2 | 0.10 | 6.2e-05 | 5.1 | 5.3 | 1.3e-07 | 0.78 | 0.02 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C4orf14 | 0.07 | 0.05 | blup | 57 | 0.06 | 3.2e-06 | -3.6 | 5.3 | 1.1e-07 | 0.51 | 0.40 | 0.50 | FALSE |