TWAS
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Usage
Models
Genes
Traits
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Traits
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Past tobacco smoking
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chr5:86,867,897-88,427,942
Best TWAS P=1.05e-07 · Best GWAS P=5.03e-07 conditioned to 0.38
86.8M
87M
87.2M
87.4M
87.6M
87.8M
88M
88.2M
88.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
TMEM161B-AS1
0.17
0.00
lasso
5
0.00
0.632
4.8
5.3
1.1e-07
0.86
0.03
0.66
TRUE
1
GTEx
Esophagus Muscularis
TMEM161B-AS1
0.19
0.04
lasso
9
0.02
0.019
4.8
5.1
3.1e-07
0.90
0.04
0.93
FALSE