Best TWAS P=2.52e-09 · Best GWAS P=2.02e-10 conditioned to 0.0156
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | RP5-1029K10.2 | 0.20 | 0.00 | enet | 49 | 0.06 | 0.00229 | 5.5 | 5.2 | 2.5e-07 | 0.34 | 0.05 | 0.47 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 0.00026 | 5.5 | -5.8 | 5.3e-09 | -0.90 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF652 | 0.06 | 0.03 | lasso | 4 | 0.02 | 0.00165 | 5.4 | -5.1 | 3.1e-07 | -0.76 | 0.16 | 0.66 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 0.00249 | 6.4 | -6.0 | 2.5e-09 | -0.87 | 0.01 | 0.97 | TRUE |