Best TWAS P=8.07e-08 · Best GWAS P=1.58e-06 conditioned to 0.704
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | ORMDL3 | 0.24 | 0.09 | enet | 21 | 0.07 | 7.8e-06 | 4.6 | 5.3 | 1.1e-07 | 0.81 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Lung | ORMDL3 | 0.16 | 0.13 | enet | 15 | 0.14 | 1.6e-10 | 4.6 | 5.3 | 1.3e-07 | 0.91 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | GSDMB | 0.08 | 0.08 | blup | 40 | 0.09 | 6.6e-09 | 4.7 | 5.4 | 8.1e-08 | 0.86 | 0.01 | 0.97 | TRUE |