Best TWAS P=7.47e-08 · Best GWAS P=1.55e-07 conditioned to 0.436
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | PSRC1 | 0.18 | 0.14 | lasso | 3 | 0.14 | 2.4e-09 | -4.8 | -5.2 | 2.4e-07 | 0.95 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | SORT1 | 0.23 | 0.16 | lasso | 4 | 0.16 | 4.6e-08 | -5.1 | -5.4 | 7.5e-08 | 0.92 | 0.01 | 0.99 | TRUE |