Best TWAS P=9.88e-08 · Best GWAS P=1.54e-07 conditioned to 0.113
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | DHX40 | 0.24 | 0.13 | lasso | 10 | 0.18 | 2.6e-08 | 5.2 | 5.2 | 1.5e-07 | 0.98 | 0.02 | 0.98 | FALSE |
2 | GTEx | Thyroid | DHX40 | 0.07 | 0.04 | lasso | 7 | 0.03 | 1.7e-03 | 5.2 | 5.2 | 2.0e-07 | 0.99 | 0.02 | 0.92 | FALSE |
3 | YFS | Blood | DHX40 | 0.01 | 0.01 | lasso | 8 | 0.01 | 1.6e-03 | 4.5 | -5.3 | 9.9e-08 | -0.81 | 0.05 | 0.88 | TRUE |