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chr19:48,464,978-49,935,001

Best TWAS P=7.18e-11 · Best GWAS P=1.16e-10 conditioned to 0.253

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	RASIP1	0.20	0.11	lasso	4	0.10	2.4e-04	5.3	-5.3	1.4e-07	0.84	0.03	0.93	FALSE
2	GTEx	Cells Transformed fibroblasts	RASIP1	0.19	0.14	lasso	6	0.20	6.1e-15	-6.0	-6.5	7.2e-11	0.92	0.02	0.98	TRUE
3	GTEx	Esophagus Mucosa	RASIP1	0.13	0.13	lasso	4	0.13	9.0e-09	5.7	-5.7	1.2e-08	0.92	0.04	0.96	FALSE
4	GTEx	Heart Left Ventricle	MAMSTR	0.26	0.18	lasso	6	0.21	3.4e-11	4.2	-5.4	5.8e-08	0.92	0.02	0.98	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	RASIP1	0.15	0.04	lasso	6	0.08	2.9e-05	-6.4	-5.5	4.1e-08	0.87	0.01	0.99	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	NTN5	0.19	0.07	lasso	5	0.08	2.5e-05	-5.7	-6.3	3.6e-10	0.89	0.04	0.95	FALSE
7	GTEx	Skin Sun Exposed Lower leg	RASIP1	0.21	0.13	enet	19	0.17	1.1e-13	5.5	-6.1	1.1e-09	0.92	0.01	0.99	FALSE
8	GTEx	Skin Sun Exposed Lower leg	NTN5	0.11	0.09	enet	18	0.05	6.2e-05	-6.0	-5.8	7.3e-09	0.82	0.02	0.98	FALSE
9	GTEx	Testis	RASIP1	0.29	0.20	lasso	8	0.30	7.5e-14	5.7	-6.3	3.3e-10	0.96	0.03	0.97	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FUT2	0.05	0.01	blup	52	0.01	6.1e-02	-6.3	6.4	2.0e-10	-0.94	0.01	0.84	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	FUT2	0.03	0.05	blup	54	0.05	1.9e-10	-6.0	6.0	2.2e-09	-0.84	0.05	0.95	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	NTN5	0.02	0.01	enet	11	0.01	7.6e-04	-5.6	-6.0	1.4e-09	0.68	0.01	0.91	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	RASIP1	0.02	0.02	blup	56	0.03	3.8e-07	-5.6	-6.3	3.4e-10	0.92	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FUT2	0.10	0.02	blup	55	0.06	6.8e-04	-5.6	6.0	2.1e-09	-0.83	0.07	0.89	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	FUT2	0.18	0.22	enet	12	0.18	6.8e-11	-5.7	5.8	5.5e-09	-0.81	0.13	0.87	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	SEC1	0.05	0.04	enet	11	0.01	8.5e-02	-5.7	5.4	6.5e-08	-0.73	0.02	0.85	FALSE
17	The Cancer Genome Atlas	Esophageal Carcinoma	FUT2	0.33	0.27	lasso	3	0.24	3.9e-08	5.1	5.2	1.6e-07	-0.67	0.15	0.84	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FUT2	0.11	0.22	blup	52	0.22	6.3e-24	-5.9	6.1	1.4e-09	-0.86	0.04	0.96	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FUT2	0.10	0.01	blup	51	0.05	9.8e-04	-5.8	5.9	2.8e-09	-0.82	0.03	0.83	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAMSTR	0.04	0.04	blup	47	0.06	3.9e-07	5.3	-5.7	1.1e-08	0.83	0.15	0.84	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	NTN5	0.05	0.04	lasso	2	0.02	6.7e-04	-5.6	-5.6	2.4e-08	0.82	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	FUT2	0.09	0.12	blup	52	0.12	4.2e-14	-5.6	5.9	2.9e-09	-0.85	0.10	0.90	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FUT2	0.05	0.08	lasso	2	0.08	6.7e-09	-5.8	5.8	6.3e-09	-0.79	0.09	0.91	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FUT2	0.06	0.00	blup	53	0.05	3.5e-04	-6.3	5.7	1.3e-08	-0.86	0.01	0.90	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FUT2	0.08	0.12	lasso	4	0.11	2.5e-05	-6.0	6.0	1.6e-09	-0.78	0.03	0.92	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	IZUMO1	0.16	0.17	lasso	7	0.15	1.4e-06	5.8	-5.8	5.2e-09	0.86	0.12	0.86	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	FUT2	0.05	0.06	blup	52	0.06	8.6e-07	-5.9	6.3	3.0e-10	-0.91	0.03	0.97	FALSE
28	The Cancer Genome Atlas	Rectum Adenocarcinoma	FUT2	0.26	0.28	lasso	10	0.22	5.2e-06	-5.6	5.9	3.7e-09	-0.86	0.06	0.90	FALSE
29	The Cancer Genome Atlas	Soft Tissue Sarcoma	RASIP1	0.05	0.06	blup	54	0.04	1.4e-03	5.1	-5.6	2.2e-08	0.77	0.04	0.49	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	FUT2	0.14	0.16	lasso	8	0.14	4.9e-10	-6.0	6.0	2.7e-09	-0.80	0.05	0.95	FALSE
31	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FUT2	0.22	0.09	lasso	8	0.13	3.0e-05	4.0	5.8	8.5e-09	-0.71	0.05	0.92	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	FUT2	0.06	0.04	blup	54	0.06	1.1e-06	5.1	6.3	2.9e-10	-0.88	0.03	0.97	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	NTN5	0.11	0.07	blup	43	0.09	2.6e-09	-5.6	-5.9	3.3e-09	0.75	0.02	0.98	FALSE