TWAS hub - FUT2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0510	0.0360	5.6e-03	0.006	0.008	-0.002	NA	0.001	8.4e-02	6.1e-02	5.2e-01	NA	2.5e-01
2	TCGA	Breast Invasive Carcinoma	0.0301	0.0136	1.7e-09	0.049	0.050	0.046	NA	0.050	2.8e-10	1.9e-10	7.4e-10	NA	2.0e-10
3	TCGA	Cervical Squamous Cell Carcinoma	0.0960	0.0420	2.3e-05	0.025	0.060	0.032	NA	0.024	2.2e-02	6.8e-04	1.0e-02	NA	2.2e-02
4	TCGA	Colon Adenocarcinoma	0.1830	0.0680	1.9e-12	0.217	0.050	0.185	NA	0.097	1.0e-12	6.8e-04	6.8e-11	NA	3.0e-06
5	TCGA	Esophageal Carcinoma	0.3310	0.1180	1.4e-06	0.268	-0.002	0.146	NA	0.238	4.3e-09	3.8e-01	2.3e-05	NA	3.9e-08
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.1102	0.0364	0.0e+00	0.221	0.217	0.216	NA	0.215	1.9e-24	6.3e-24	7.0e-24	NA	1.0e-23
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0980	0.0510	6.5e-04	0.015	0.048	0.022	NA	0.027	4.6e-02	9.8e-04	2.0e-02	NA	1.1e-02
8	TCGA	Brain Lower Grade Glioma	0.0249	0.0157	3.3e-03	0.037	0.012	0.020	NA	0.031	4.8e-05	1.4e-02	2.3e-03	NA	1.8e-04
9	TCGA	Lung Adenocarcinoma	0.0947	0.0393	1.3e-13	0.125	0.122	0.097	NA	0.121	2.0e-14	4.2e-14	1.9e-11	NA	6.0e-14
10	TCGA	Lung Squamous Cell Carcinoma	0.0489	0.0228	1.1e-06	0.081	0.059	0.069	NA	0.075	1.8e-09	2.7e-07	2.8e-08	NA	6.7e-09
11	TCGA	Ovarian Serous Cystadenocarcinoma	0.0570	0.0350	6.2e-04	0.003	0.048	0.026	NA	0.018	1.8e-01	3.5e-04	6.4e-03	NA	2.0e-02
12	TCGA	Pancreatic Adenocarcinoma	0.0830	0.0450	6.7e-04	0.121	0.040	0.074	NA	0.110	9.1e-06	8.8e-03	5.0e-04	NA	2.5e-05
13	TCGA	Prostate Adenocarcinoma	0.0516	0.0240	7.5e-07	0.060	0.059	0.045	NA	0.046	6.4e-07	8.6e-07	1.5e-05	NA	1.3e-05
14	TCGA	Rectum Adenocarcinoma	0.2590	0.0960	1.4e-05	0.285	0.150	0.210	NA	0.225	2.0e-07	2.3e-04	1.2e-05	NA	5.2e-06
15	TCGA	Stomach Adenocarcinoma	0.1440	0.0510	4.6e-11	0.156	0.126	0.133	NA	0.136	2.2e-11	2.0e-09	8.1e-10	NA	4.9e-10
16	TCGA	Testicular Germ Cell Tumors	0.2210	0.1070	5.3e-06	0.088	0.102	0.125	NA	0.127	5.0e-04	1.9e-04	3.6e-05	NA	3.0e-05
17	TCGA	Thyroid Carcinoma	0.0550	0.0270	1.9e-06	0.042	0.062	0.045	NA	0.045	5.5e-05	1.1e-06	3.2e-05	NA	3.4e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
High cholesterol (Self-reported)	32.4	57.4	65.8	-7.0	-7.6	-7.7	-8.1	-7.7	-7.7	-7.4	-5.5	-7.5	-7.9	-7.6	-7.8	-8.0	-8.0	-8.1	-7.0	-7.8
Cardiovascular Disease	20.1	66.4	79.6	-7.3	-8.1	-8.2	-8.7	-8.2	-8.1	-7.9	-6.5	-8.4	-8.7	-8.2	-8.9	-8.4	-8.4	-8.9	-7.1	-8.1
Crohns Disease (2012)	15.2	24.4	34.6	-3.4	-4.5	-5.1	-5.6	-4.9	-4.9	-4.7	-3.3	-5.2	-5.6	-4.9	-5.7	-5.3	-5.4	-5.9	-4.6	-4.3
Medication: Cholesterol lowering	14.9	23.1	29.1	-4.1	-4.6	-4.7	-5.3	-5.0	-5.1	-5.1	-3.6	-4.6	-5.3	-4.3	-5.3	-5.1	-5.3	-5.4	-3.9	-4.6
Crohns Disease (2017)	14.8	32.4	45.4	-4.1	-5.4	-5.9	-6.5	-6.1	-5.7	-4.6	-4.2	-6.0	-6.4	-5.5	-6.6	-5.6	-6.0	-6.7	-5.4	-5.1
Medication: Simvastatin	14.7	21.6	31.4	-3.2	-4.3	-4.4	-5.3	-5.0	-4.6	-5.2	-3.1	-4.3	-5.6	-4.0	-5.3	-4.9	-5.1	-5.3	-4.2	-4.3
Alcohol intake frequency.	14.6	34.0	40.4	6.4	6.0	6.0	5.8	5.2	6.1	5.9	3.5	5.9	5.8	5.7	6.0	6.3	5.9	6.0	5.8	6.3
Mouth/teeth dental problems: Dentures	14.4	24.2	30.5	-4.1	-4.8	-4.9	-5.3	-5.0	-4.5	-5.3	-5.1	-4.9	-5.4	-4.6	-4.9	-4.8	-5.5	-5.1	-4.3	-4.9
LDL Cholesterol	14.1	22.4	29.7	-4.7	-4.3	-4.7	-4.8	-3.8	-5.0	-4.7	-3.8	-5.3	-4.8	-5.0	-5.3	-5.5	-4.9	-5.3	-3.7	-4.2
Medication for cholesterol	13.8	20.9	26.4	4.0	4.6	4.2	4.9	4.7	4.1	5.1	3.4	4.3	4.9	4.5	4.9	4.5	4.7	5.0	4.9	4.6
Alcohol intake versus 10 years previously	13.4	20.1	23.7	4.4	4.4	4.6	4.7	3.9	4.4	4.9	2.5	4.8	4.8	4.5	4.7	4.8	4.8	4.8	4.2	4.6
Average weekly spirits intake	13.2	16.4	20.2	4.3	4.0	4.0	4.0	3.5	4.0	4.1	3.6	4.1	3.9	4.3	4.2	4.5	4.0	4.1	3.7	4.2
Mouth/teeth dental problems	12.8	19.6	23.5	4.2	4.2	4.3	4.6	4.2	4.4	4.8	3.9	4.5	4.6	4.4	4.8	4.8	4.8	4.8	3.5	4.4
Cholesterol lowering medication	11.6	17.0	25.9	-3.3	-3.9	-3.6	-4.5	-3.9	-3.6	-5.1	-2.6	-4.3	-4.7	-3.9	-4.7	-4.1	-4.5	-4.6	-4.3	-3.8
Medication: Atorvastatin	11.3	13.9	16.9	-3.9	-3.8	-3.7	-3.6	-3.4	-3.9	-3.3	-4.1	-3.8	-3.4	-4.1	-3.8	-3.8	-3.7	-4.0	-3.5	-3.6
Hypertension (Self-reported)	10.4	28.8	32.3	-5.0	-5.5	-5.4	-5.7	-5.5	-5.2	-5.3	-4.5	-5.4	-5.4	-5.3	-5.6	-5.2	-5.7	-5.7	-5.0	-5.5
Medication for cholesterol, blood pressure or diabetes	9.9	16.4	21.8	3.2	3.8	4.2	4.5	4.2	4.2	3.9	2.6	4.2	4.5	3.9	4.6	4.3	4.3	4.7	3.3	3.8
Medication: Bendroflumethiazide	9.9	15.1	19.2	-3.7	-4.1	-3.8	-4.0	-4.4	-4.0	-3.5	-2.9	-3.6	-3.7	-3.8	-4.2	-3.8	-3.8	-4.2	-4.2	-4.1
Serious illness, injury or assault of a close relative in last 2 years	9.8	11.3	17.6	-2.8	-2.9	-3.2	-3.5	-2.8	-2.9	-4.2	-2.4	-3.8	-4.0	-3.1	-3.9	-3.7	-3.7	-3.9	-2.6	-3.0
Systolic Blood Pressure	9.6	48.0	58.7	-7.5	-6.9	-7.0	-6.8	-6.2	-7.1	-7.2	-5.3	-7.2	-6.7	-7.2	-7.1	-7.7	-6.8	-7.0	-6.3	-7.2
Hypothyroidism (self reported)	9.2	21.1	26.1	-4.9	-4.5	-4.5	-4.7	-3.7	-4.8	-5.0	-2.7	-4.9	-4.8	-4.5	-4.9	-5.1	-5.0	-4.8	-3.8	-4.7
Number of children fathered	9.1	10.3	12.8	3.1	3.4	3.2	3.5	3.5	3.1	3.2	2.2	3.0	3.5	3.2	3.3	3.3	2.9	3.2	3.0	3.6
Number of self-reported non-cancer illnesses	9.1	15.8	20.9	-3.5	-3.9	-3.7	-4.3	-3.6	-3.8	-4.6	-2.5	-3.9	-4.5	-3.9	-4.4	-4.2	-4.2	-4.5	-3.6	-3.9
Peak expiratory flow (PEF)	8.8	20.5	26.1	4.0	4.3	4.4	5.1	4.4	4.7	4.8	3.7	4.6	5.1	4.0	5.1	4.6	5.0	5.1	3.5	4.2
Vascular/heart problems diagnosed by doctor	8.1	22.1	27.4	4.1	4.7	4.5	5.1	5.0	4.5	4.9	3.6	4.7	4.9	4.5	5.2	4.6	5.0	5.2	4.4	4.7
Lupus	8.0	12.1	15.8	3.4	3.5	3.5	3.7	3.1	4.0	3.1	2.5	3.7	3.9	3.2	3.8	3.6	3.7	3.8	2.9	3.3
Birth weight	7.9	17.1	21.9	3.6	4.1	4.2	4.2	3.8	4.2	3.8	3.3	4.2	4.3	4.7	4.4	4.4	4.0	4.5	4.7	3.9
Diabetes (father)	7.8	9.6	14.1	2.8	3.3	3.5	3.3	3.8	3.5	1.7	3.4	2.9	2.8	3.1	3.3	3.0	2.6	3.4	2.6	3.1
High blood pressure	7.6	21.3	24.3	-4.3	-4.8	-4.6	-4.9	-4.9	-4.5	-4.5	-3.6	-4.6	-4.6	-4.6	-4.9	-4.4	-4.9	-4.9	-4.4	-4.8
Comparative body size at age 10	7.4	20.3	27.8	3.6	4.5	4.3	4.9	4.7	4.6	4.3	3.1	4.3	4.9	4.3	5.1	4.5	4.2	5.0	5.3	4.4
Triglycerides	7.3	11.9	16.4	-3.0	-3.3	-3.6	-3.6	-3.2	-3.6	-2.8	-3.4	-4.0	-3.9	-3.6	-3.5	-3.5	-3.9	-3.8	-2.8	-3.0
Lung FEV1/FVC ratio	7.2	36.4	46.5	5.3	5.9	6.1	6.7	6.3	6.2	5.6	4.5	6.2	6.6	6.0	6.8	6.3	6.1	6.7	5.0	5.8
Medication: Blood pressure	7.2	13.7	16.3	-3.5	-3.9	-3.4	-3.8	-4.0	-3.3	-3.9	-3.7	-3.4	-3.6	-3.5	-3.9	-3.4	-3.7	-3.8	-3.9	-3.8
Number of treatments/medications taken	7.0	12.5	16.4	-3.4	-3.6	-3.4	-3.7	-3.2	-3.4	-4.0	-2.1	-3.7	-3.9	-3.6	-4.0	-3.7	-3.4	-3.9	-3.1	-3.5
Bipolar Disorder or Schizophrenia	6.7	16.4	19.2	-3.9	-4.2	-4.4	-4.2	-3.9	-4.2	-3.5	-3.0	-4.1	-4.2	-4.3	-4.1	-4.4	-3.7	-4.2	-4.0	-4.4
Medication: Levothyroxine sodium	6.2	10.5	14.7	-3.7	-3.2	-2.9	-3.0	-2.6	-3.3	-3.8	-1.2	-3.3	-3.1	-3.2	-3.7	-3.7	-3.3	-3.5	-3.3	-3.4
Irritable Bowel Disease (IBD)	6.1	14.5	21.7	-2.4	-3.6	-3.9	-4.4	-4.2	-3.7	-2.6	-3.1	-4.2	-4.3	-3.9	-4.6	-3.6	-3.9	-4.7	-3.7	-3.1
Age when periods started (menarche)	5.9	14.1	17.3	-3.4	-3.7	-3.7	-4.0	-3.7	-3.7	-3.9	-2.2	-3.6	-3.9	-3.5	-4.1	-4.0	-4.1	-4.2	-3.7	-3.9
Hypothyroidism/myxoedema (self-reported)	5.9	11.4	14.7	-3.8	-3.4	-3.1	-3.3	-2.6	-3.5	-3.8	-1.2	-3.6	-3.4	-3.4	-3.7	-3.8	-3.6	-3.6	-3.2	-3.5
Schizophrenia (2014)	5.8	12.8	16.2	-3.7	-3.9	-3.8	-3.5	-3.5	-3.7	-2.7	-3.3	-3.5	-3.3	-3.9	-3.4	-3.7	-3.4	-3.5	-3.6	-4.0
Blood Platelet Count	5.8	67.1	85.6	-9.2	-8.3	-7.8	-8.3	-7.3	-8.5	-8.5	-5.7	-8.6	-8.3	-8.2	-8.6	-9.0	-8.2	-8.4	-7.0	-8.7
Waist Hip Ratio (WHR)	5.7	25.7	36.0	-6.0	-5.2	-4.7	-4.9	-4.5	-5.3	-5.8	-3.5	-4.7	-4.8	-4.6	-5.1	-5.6	-5.3	-4.9	-5.3	-5.6
High blood pressure (mother)	5.7	8.0	9.5	-3.1	-2.9	-2.8	-2.8	-2.5	-2.7	-2.8	-2.3	-3.0	-2.8	-3.1	-3.1	-3.0	-2.5	-2.9	-3.0	-2.9
Medication: Blood pressure	5.7	10.0	15.1	-2.2	-3.0	-3.4	-3.5	-3.5	-3.1	-2.8	-2.0	-3.2	-3.5	-3.2	-3.9	-3.3	-3.0	-3.9	-2.6	-2.9
Chronotype (morning person)	5.5	12.8	17.7	3.5	3.8	3.6	3.8	3.5	3.4	3.4	2.0	3.7	3.7	3.7	3.6	3.6	3.6	3.5	4.2	3.8
Bipolar Disorder (2018)	5.4	8.5	10.2	-2.6	-3.0	-3.2	-3.2	-2.7	-3.2	-2.3	-2.4	-3.0	-3.2	-3.0	-3.0	-3.1	-2.9	-3.1	-2.7	-2.8
Comparative height size at age 10	5.2	28.4	40.0	4.8	5.0	5.3	5.8	5.7	5.7	5.0	3.6	5.5	5.5	5.0	6.3	5.7	5.2	6.0	4.9	5.2
Average weekly champagne plus white wine intake	5.1	7.1	9.4	-2.5	-3.1	-2.9	-2.9	-2.8	-2.6	-1.8	-2.4	-2.6	-2.7	-2.8	-2.2	-2.2	-2.7	-2.5	-3.0	-2.9
Illnesses of mother	4.8	6.0	9.9	2.2	2.1	2.1	2.5	2.6	2.2	3.1	2.2	2.5	2.7	2.2	2.7	2.5	2.5	2.6	2.2	2.2
Chest pain or discomfort	4.7	6.8	13.0	-1.1	-2.1	-2.1	-3.1	-3.0	-2.1	-3.3	-1.3	-2.5	-3.5	-2.1	-3.6	-2.6	-2.5	-3.4	-2.1	-2.0
Systolic blood pressure, automated reading	4.6	13.3	16.3	-4.0	-3.6	-3.8	-3.6	-3.0	-3.9	-3.6	-3.0	-3.9	-3.5	-3.8	-3.7	-3.9	-3.7	-3.7	-3.4	-3.7
Ever smoked	4.3	7.6	8.5	2.6	2.9	2.8	2.8	2.5	2.8	2.6	2.6	2.7	2.9	2.7	2.7	2.7	2.9	2.8	2.6	2.8
Hip circumference	4.2	18.2	35.3	5.9	4.4	4.3	3.7	3.2	4.6	4.5	3.0	4.2	3.5	4.7	3.5	5.0	4.1	3.5	4.2	5.0
Friendships satisfaction	4.2	5.2	6.4	-2.3	-2.2	-2.2	-2.2	-2.2	-2.3	-2.4	-2.3	-2.4	-2.2	-2.3	-2.5	-2.5	-2.1	-2.4	-2.0	-2.3
Schizophrenia (2018)	4.1	8.4	11.9	-3.1	-3.2	-3.0	-2.9	-2.8	-2.9	-2.5	-1.9	-2.9	-2.9	-3.2	-2.9	-3.1	-2.5	-2.8	-3.0	-3.5
Medication: Lisinopril	4.1	5.3	6.9	-2.0	-2.3	-2.2	-2.5	-2.6	-2.2	-2.4	-2.6	-2.2	-2.5	-1.6	-2.4	-2.0	-2.5	-2.5	-2.0	-2.3
Alcohol drinker status: Previous	4.1	4.7	6.7	1.6	2.2	2.5	2.5	2.6	2.3	1.6	1.6	2.1	2.4	1.7	2.3	2.0	2.2	2.5	1.7	2.2
Birth weight of first child	4.0	7.3	9.5	2.7	2.5	2.5	2.9	2.2	3.1	2.7	1.7	3.0	3.0	2.6	3.1	3.1	2.9	3.1	1.9	2.4
Medication: Amlodipine	4.0	5.6	8.7	-1.6	-2.5	-2.3	-2.7	-2.6	-2.2	-1.9	-1.7	-2.6	-2.7	-2.4	-3.0	-2.0	-2.2	-2.8	-2.3	-2.1
Age at first live birth	4.0	7.1	9.8	-3.1	-2.7	-2.9	-2.5	-1.8	-2.8	-2.7	-1.6	-3.1	-2.7	-3.0	-2.4	-2.9	-2.8	-2.5	-2.5	-2.8
Illnesses of father: High blood pressure	3.9	4.8	9.0	-1.9	-1.9	-2.1	-2.2	-1.6	-2.0	-3.0	-1.4	-2.4	-2.8	-1.9	-2.4	-2.4	-2.6	-2.4	-1.8	-2.0
Relative age voice broke	3.8	5.7	7.0	-2.1	-2.3	-2.4	-2.5	-2.3	-2.5	-2.2	-2.2	-2.4	-2.6	-2.3	-2.6	-2.5	-2.5	-2.6	-2.2	-2.3
Osteoarthritis (self-reported)	3.8	4.9	6.3	2.0	2.3	2.5	2.4	2.2	2.5	1.3	1.9	2.3	2.3	2.5	2.3	2.2	2.2	2.2	2.3	2.2
Myopia	3.8	5.6	8.5	2.6	2.6	2.7	2.3	2.4	2.5	1.9	2.3	2.2	2.1	2.2	2.0	2.2	2.2	2.1	2.4	2.9
Body Mass Index (BMI) (2010)	3.7	5.0	6.2	2.1	2.2	2.3	2.3	2.3	2.1	2.2	2.0	2.1	2.3	2.3	2.1	2.3	2.2	2.2	2.5	2.4
Alcohol usually taken with meals	3.7	5.9	8.5	-2.5	-2.7	-2.4	-2.5	-2.3	-2.5	-2.2	-1.4	-2.3	-2.5	-2.6	-2.5	-2.5	-2.3	-2.4	-2.9	-2.6
Diastolic blood pressure, automated reading	3.6	11.1	15.0	-3.0	-3.2	-3.4	-3.7	-3.4	-3.5	-3.1	-2.4	-3.7	-3.5	-3.0	-3.9	-3.3	-3.5	-3.8	-2.7	-3.2
Sitting height	3.5	24.7	34.3	5.9	4.9	5.2	4.7	4.0	5.2	5.2	4.1	5.2	4.3	5.2	4.5	5.8	5.2	4.7	4.6	5.5
Arm fat-free mass (right)	3.2	16.5	30.4	5.4	3.6	3.5	3.6	2.8	4.3	5.5	1.5	4.2	3.8	3.9	3.9	5.1	4.2	3.8	3.9	4.4
Age at First Birth	3.1	4.5	8.5	-2.1	-2.5	-2.5	-2.1	-2.4	-2.0	-1.0	-1.9	-2.1	-1.6	-2.6	-1.8	-1.9	-1.8	-1.8	-2.9	-2.6
Relative age of first facial hair	3.1	6.4	8.1	-2.5	-2.7	-2.8	-2.6	-2.3	-2.9	-1.8	-2.5	-2.6	-2.6	-2.5	-2.3	-2.5	-2.6	-2.5	-2.5	-2.7
Arm predicted mass (right)	3.1	15.6	28.5	5.2	3.5	3.5	3.6	2.7	4.1	5.3	1.2	4.2	3.7	3.9	3.9	4.9	4.0	3.7	3.7	4.2
Supplements: Vitamin C	3.1	3.7	4.8	1.7	1.8	2.0	2.1	1.8	2.0	2.1	1.2	1.8	2.1	1.9	2.1	2.2	2.2	2.1	1.8	1.8
Severe depression (siblings)	2.9	3.2	4.6	-1.9	-1.9	-1.7	-1.9	-1.4	-2.0	-1.7	-1.1	-1.8	-2.0	-2.1	-1.9	-2.1	-1.8	-1.9	-1.2	-1.6
Hair/balding pattern: Pattern 4	2.9	7.0	14.6	1.6	2.8	3.0	2.9	3.8	2.6	1.6	2.7	1.7	2.5	2.3	2.8	2.3	2.3	2.9	3.0	2.9
Arm predicted mass (left)	2.9	14.7	27.4	5.2	3.5	3.4	3.3	2.5	3.9	5.2	1.1	4.0	3.4	3.9	3.6	4.8	3.8	3.5	3.9	4.2
Age at last live birth	2.8	4.0	6.1	-2.5	-2.1	-2.3	-1.8	-1.3	-2.1	-2.1	-0.9	-2.0	-1.9	-2.2	-1.8	-2.3	-2.1	-1.9	-1.9	-2.2
Arm fat-free mass (left)	2.8	14.4	27.0	5.2	3.4	3.3	3.3	2.5	3.9	5.2	1.0	4.0	3.4	3.9	3.6	4.8	3.8	3.4	3.6	4.2
Medication for hormone replacement therapy	2.7	3.0	5.0	-2.0	-1.7	-1.8	-1.8	-1.2	-1.8	-1.7	-0.0	-1.7	-1.7	-2.2	-1.7	-2.2	-1.6	-1.7	-1.4	-1.9
Prostate Cancer	2.5	3.5	4.4	-2.1	-2.0	-1.9	-2.0	-1.9	-2.1	-1.6	-1.1	-1.8	-1.9	-2.0	-1.6	-2.0	-1.8	-1.6	-1.9	-2.1
Diabetes (mother)	2.5	3.2	5.4	1.6	2.0	2.2	1.8	1.9	1.9	0.9	2.0	1.6	1.6	2.3	1.5	1.8	1.6	1.7	1.6	1.9
Hair/balding pattern: Pattern 2	2.5	3.2	5.4	1.3	1.6	1.7	1.9	1.5	1.6	2.3	1.2	1.7	2.0	1.8	2.1	2.1	1.7	2.0	1.6	1.7
Pulse wave Arterial Stiffness index	2.5	2.9	5.9	1.9	2.0	2.1	1.6	1.0	1.8	1.2	2.0	1.7	1.7	2.4	1.1	1.9	1.6	1.3	1.2	1.8
Pulse rate, automated reading	2.5	8.0	10.9	-2.7	-2.8	-2.9	-3.2	-3.1	-3.0	-2.4	-1.6	-3.3	-3.0	-2.9	-3.2	-2.7	-2.8	-3.1	-2.3	-2.8
Qualifications: nursing, teaching	2.5	3.8	5.6	1.4	1.9	2.1	2.4	1.9	2.1	1.4	2.1	2.1	2.3	2.0	2.1	2.0	2.1	2.2	1.1	1.6
Primary Biliary Cirrhosis	2.4	3.4	4.2	-1.7	-2.0	-1.9	-1.8	-1.8	-1.8	-1.8	-1.2	-1.7	-1.9	-2.0	-1.9	-1.9	-1.8	-1.9	-2.1	-2.0
Average weekly fortified wine intake	2.4	2.9	4.2	1.2	1.5	1.8	2.0	1.4	1.8	1.5	1.4	1.9	2.0	1.7	1.8	1.9	2.0	1.9	1.4	1.4
Weight	2.4	11.7	25.1	5.0	3.4	3.3	2.8	2.2	3.6	4.2	1.9	3.3	2.8	3.7	2.8	4.2	3.3	2.7	3.5	4.1
Trunk fat-free mass	2.4	13.6	26.0	4.6	3.1	3.1	3.5	2.6	3.8	5.1	0.7	4.1	3.5	3.6	3.9	4.6	3.8	3.7	3.3	3.7
Trunk predicted mass	2.4	13.8	26.3	4.7	3.1	3.1	3.5	2.6	3.8	5.1	0.6	4.1	3.5	3.6	3.9	4.6	3.8	3.7	3.3	3.7
Breastfed as a baby	2.4	3.0	4.4	-1.8	-2.0	-1.9	-1.9	-2.0	-2.1	-1.1	-0.7	-1.5	-1.6	-1.6	-1.7	-1.6	-2.1	-1.8	-1.2	-2.0
Medication: Aspirin	2.4	3.1	5.4	-1.2	-1.7	-1.4	-2.0	-2.0	-1.5	-2.3	-1.6	-1.6	-1.9	-1.5	-2.3	-1.7	-1.8	-2.1	-1.4	-1.5
Medication: Gliclazide	2.4	2.7	4.2	1.4	1.7	1.9	1.8	1.9	1.8	0.8	0.0	1.7	1.7	1.6	1.9	1.5	1.2	1.7	2.0	1.9
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	6.2	-2.5	-1.8	-1.4	-1.5	-0.8	-1.6	-2.0	-1.2	-1.8	-1.4	-1.7	-1.2	-1.7	-2.2	-1.2	-1.1	-2.0
Whole body fat-free mass	2.3	13.0	23.8	4.8	3.2	3.1	3.2	2.5	3.8	4.9	0.9	3.8	3.2	3.5	3.5	4.5	3.6	3.3	3.5	3.9
Pulse rate	2.2	3.7	6.2	-1.3	-1.7	-1.9	-2.3	-2.1	-2.0	-1.7	-0.5	-2.2	-2.2	-1.9	-2.4	-2.0	-2.1	-2.5	-1.6	-1.6
Back pain experienced in last month	2.2	3.3	5.4	2.0	1.6	1.8	1.7	1.2	1.7	2.3	0.8	2.0	1.7	1.8	1.9	2.2	2.1	1.9	1.5	1.9
Basal metabolic rate	2.2	12.4	24.7	5.0	3.2	3.1	3.0	2.3	3.7	4.7	1.2	3.6	3.0	3.6	3.2	4.4	3.5	3.1	3.5	3.9
Medication: Atenolol	2.1	2.6	4.6	-1.2	-1.3	-1.6	-1.7	-1.6	-1.3	-1.8	-2.1	-1.6	-1.5	-1.5	-1.8	-1.8	-1.9	-1.9	-1.0	-1.5
Medication: Ramipril	2.1	2.7	4.0	-1.3	-1.7	-1.5	-1.7	-1.8	-1.6	-1.7	-1.7	-1.4	-1.6	-1.3	-1.7	-1.4	-2.0	-1.9	-1.6	-1.7
Whole body water mass	2.1	11.9	22.9	4.7	3.0	2.9	3.1	2.4	3.6	4.8	0.7	3.6	3.1	3.4	3.4	4.4	3.4	3.2	3.4	3.7
Length of working week for main job	2.0	2.3	3.9	1.3	1.5	1.5	1.5	1.5	1.3	1.1	1.9	1.7	1.4	2.0	1.5	1.4	1.1	1.5	1.8	1.3
HbA1C	1.9	2.1	3.7	1.6	1.6	1.5	1.6	1.3	1.5	1.3	-0.7	1.2	1.1	1.7	1.4	1.6	1.4	1.3	1.9	1.7
Other serious medical condition/disability diagnosed by doctor	1.9	2.4	4.4	-1.3	-1.6	-1.6	-1.8	-1.4	-1.7	-1.5	-1.4	-1.5	-1.9	-1.3	-1.4	-1.6	-2.1	-1.6	-1.0	-1.5
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	3.9	1.7	2.0	1.8	1.5	1.7	1.5	0.2	1.7	1.5	1.0	1.7	0.9	1.0	1.2	1.2	1.2	2.0
Standing height	1.9	18.9	24.6	5.0	4.3	4.3	4.2	3.9	4.7	4.0	3.9	4.7	3.8	4.4	4.5	4.9	4.1	4.5	4.0	4.5
Leg fat-free mass (right)	1.9	10.1	19.4	4.4	3.1	2.8	2.8	2.5	3.5	4.0	1.1	3.1	2.6	3.1	2.9	3.8	3.0	2.7	3.5	3.7
Asthma (self-reported)	1.9	3.9	5.7	2.1	2.1	2.0	1.9	2.2	2.1	2.1	2.2	1.5	1.7	1.6	1.5	2.0	2.4	1.8	1.7	2.3
Illnesses of father: None of the above (group 1)	1.9	2.4	3.0	1.5	1.7	1.6	1.6	1.7	1.7	1.5	1.0	1.6	1.7	1.5	1.6	1.4	1.5	1.6	1.3	1.6
Ever taken oral contraceptive pill	1.9	2.1	6.4	1.2	1.8	1.6	1.5	1.3	1.4	0.3	2.5	1.6	1.4	1.8	0.8	1.0	1.3	1.1	1.3	1.3
Average weekly beer plus cider intake	1.9	2.8	4.2	-0.9	-1.5	-2.0	-2.0	-1.8	-1.8	-0.6	-1.8	-1.9	-1.7	-1.8	-1.9	-1.7	-1.7	-2.0	-1.0	-1.3
Asthma	1.8	3.5	5.4	2.1	2.0	1.9	1.8	1.9	2.0	2.1	2.2	1.5	1.6	1.5	1.4	1.9	2.3	1.7	1.5	2.1
Leg predicted mass (right)	1.8	9.7	18.6	4.3	3.0	2.8	2.7	2.4	3.4	3.9	1.0	3.0	2.6	3.1	2.9	3.8	3.0	2.7	3.4	3.6
Current tobacco smoking	1.7	2.7	4.6	2.0	1.8	1.9	1.6	1.0	1.9	0.7	2.0	2.1	1.3	2.1	1.2	1.5	1.9	1.4	1.2	1.5
Leg predicted mass (left)	1.7	9.1	19.3	4.4	2.8	2.7	2.5	2.1	3.3	3.9	0.9	3.0	2.4	3.1	2.6	3.7	2.9	2.5	3.3	3.5
Forced expiratory volume in 1-second (FEV1)	1.7	5.7	7.9	2.4	2.3	2.2	2.5	2.4	2.6	2.4	2.3	2.4	2.3	2.0	2.8	2.5	2.5	2.7	2.0	2.3
Medication: Aspirin	1.7	2.3	3.8	-1.0	-1.4	-1.1	-1.7	-1.8	-1.2	-1.9	-1.9	-1.3	-1.6	-1.2	-1.9	-1.3	-1.6	-1.8	-1.0	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.5	-1.5	-1.6	-1.4	-1.2	-0.9	-1.5	-1.0	-1.9	-1.4	-1.2	-1.6	-1.4	-1.5	-1.5	-1.4	-1.4	-1.4
Mother’s age at death	1.7	2.1	5.2	-0.1	1.2	1.5	2.0	2.3	1.2	0.9	0.7	1.3	2.2	1.2	1.9	0.9	1.1	1.8	1.4	1.0
Breast Cancer	1.6	3.8	5.5	1.7	2.0	2.3	2.1	2.0	2.1	1.1	0.7	2.3	2.0	2.0	1.9	1.9	1.9	1.9	2.3	2.0
Neuroticism (2016)	1.6	2.3	4.8	-0.8	-1.2	-1.7	-1.9	-1.6	-1.4	-1.7	-0.0	-1.9	-2.2	-1.2	-1.7	-1.4	-1.8	-1.7	-0.9	-1.3
Leg fat-free mass (left)	1.6	8.7	18.6	4.3	2.8	2.6	2.5	2.0	3.2	3.9	0.9	2.9	2.4	3.0	2.6	3.7	2.8	2.4	3.2	3.4
Medication: Lansoprazole	1.6	1.8	3.3	1.5	1.2	1.4	1.4	0.9	1.4	1.5	-0.3	1.5	1.6	1.6	1.1	1.8	1.5	1.2	0.9	1.4
Pulse wave peak to peak time	1.6	1.8	4.1	-1.6	-1.6	-1.7	-1.2	-0.6	-1.4	-0.8	-1.8	-1.3	-1.3	-2.0	-0.7	-1.4	-1.2	-0.9	-0.9	-1.5
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	4.5	-1.5	-1.5	-1.4	-1.5	-1.6	-1.6	-1.1	-1.7	-1.8	-1.4	-1.7	-2.1	-1.7	-1.3	-2.0	-1.3	-1.4
Height	1.5	28.0	36.4	5.8	5.0	5.1	5.2	4.8	5.3	5.2	4.4	5.8	4.8	5.4	5.8	6.0	5.2	5.6	4.8	5.5
Respiratory disease	1.5	3.4	5.5	2.3	1.9	2.0	1.8	1.6	2.1	1.8	1.6	1.8	1.5	1.8	1.4	2.0	2.3	1.6	1.4	2.1
Trunk fat mass	1.5	6.5	16.7	4.1	2.8	2.7	1.7	1.3	2.7	2.4	2.5	2.3	1.7	3.1	1.5	3.0	2.1	1.5	2.7	3.3
Had menopause	1.5	1.9	3.1	0.8	1.3	1.5	1.5	1.6	1.1	0.9	1.2	1.5	1.5	1.4	1.8	1.2	1.4	1.8	1.2	1.2
Exposure to tobacco smoke at home	1.5	1.7	2.8	-1.3	-1.4	-1.6	-1.3	-0.7	-1.2	-1.4	-0.4	-1.4	-1.4	-1.7	-1.1	-1.6	-1.5	-1.3	-1.1	-1.5
Whole body fat mass	1.5	6.4	16.2	4.0	2.8	2.7	1.8	1.3	2.6	2.5	2.3	2.4	1.8	3.1	1.5	3.0	2.2	1.6	2.8	3.2
Family relationship satisfaction	1.5	1.9	4.0	-1.0	-1.2	-1.3	-1.4	-1.2	-1.0	-2.0	-1.3	-1.4	-1.7	-1.4	-1.6	-1.4	-1.2	-1.4	-1.4	-1.1
Smoking status: Current	1.5	2.4	4.1	1.8	1.7	1.8	1.5	1.1	1.8	0.6	1.9	1.9	1.2	2.0	1.2	1.4	1.7	1.3	1.2	1.4
Illnesses of siblings	1.4	2.0	5.2	0.6	0.9	1.1	1.5	1.7	1.0	2.3	1.3	1.1	1.7	0.9	1.9	1.4	1.6	1.8	1.0	0.9
Falls in the last year	1.4	1.9	5.0	1.1	1.4	1.7	1.4	1.3	1.5	0.0	2.2	1.6	0.9	1.4	1.2	1.0	1.5	1.4	1.3	1.3
Pulse wave reflection index	1.4	1.7	3.6	1.7	1.6	1.5	1.1	1.1	1.4	0.7	1.4	1.2	0.8	1.9	0.9	1.4	1.1	1.0	1.5	1.5
Loud music exposure frequency	1.4	1.5	4.5	1.0	1.5	1.1	1.2	2.1	1.3	0.8	1.5	0.3	0.9	0.8	1.0	0.8	0.9	0.9	1.8	1.6
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	3.8	1.9	1.6	1.5	0.9	0.9	1.3	0.9	0.8	0.9	0.6	1.5	0.8	1.4	1.3	0.9	1.9	1.9
Ever had bowel cancer screening	1.4	1.6	3.9	-0.3	-1.2	-1.2	-1.6	-1.2	-1.2	-1.1	-1.3	-1.1	-1.7	-1.1	-1.2	-1.1	-2.0	-1.5	-1.2	-0.9
Osteoporosis (self-reported)	1.4	1.7	3.8	-1.5	-1.5	-1.7	-1.1	-0.7	-1.4	-0.6	-1.2	-1.4	-1.2	-1.9	-0.9	-1.4	-1.1	-1.0	-1.4	-1.4
Leg fat mass (left)	1.4	5.3	14.7	3.8	2.5	2.3	1.6	1.1	2.3	2.7	1.7	2.1	1.6	2.8	1.3	2.8	2.1	1.3	2.5	3.0
Ovarian Cancer	1.3	1.7	3.1	1.0	0.8	1.3	1.6	1.3	1.2	1.8	0.1	1.6	1.6	1.1	1.7	1.5	1.4	1.6	0.5	1.1
Number of incorrect matches in round	1.3	2.1	3.4	1.6	1.7	1.8	1.5	1.8	1.8	-0.0	1.0	1.6	1.1	1.6	1.1	1.1	1.0	1.2	1.7	1.7
Past tobacco smoking	1.3	2.3	3.6	-1.7	-1.6	-1.5	-1.5	-1.5	-1.5	-1.9	-1.1	-1.2	-1.7	-1.4	-1.4	-1.6	-1.5	-1.4	-1.5	-1.9
Fluid intelligence score	1.3	2.8	7.3	-0.9	-1.8	-1.7	-2.0	-2.7	-1.6	-0.8	-0.6	-1.2	-1.9	-1.4	-2.2	-1.3	-1.0	-2.0	-2.0	-1.7
Impedance of arm (right)	1.3	6.2	22.0	-3.0	-1.7	-1.5	-2.2	-1.1	-2.2	-4.7	0.9	-2.4	-2.8	-1.8	-2.5	-3.2	-3.1	-2.3	-1.9	-2.3
Emphysema/chronic bronchitis	1.3	1.4	3.7	-1.1	-1.4	-1.0	-1.2	-1.9	-1.3	-1.0	-0.9	-0.3	-1.0	-0.6	-1.3	-0.9	-1.0	-1.2	-1.7	-1.6
Leg fat mass (right)	1.3	5.1	13.8	3.7	2.4	2.3	1.5	1.0	2.3	2.6	1.6	2.1	1.6	2.7	1.2	2.7	2.1	1.3	2.4	2.9
Guilty feelings	1.3	2.0	4.5	-0.3	-0.8	-1.3	-1.6	-1.6	-1.1	-1.9	-0.6	-1.4	-2.0	-1.1	-2.1	-1.5	-1.5	-2.0	-0.5	-0.8
Unable to work because of sickness or disability	1.3	1.6	3.3	1.8	1.3	1.5	1.2	0.5	1.4	1.0	0.3	1.6	1.0	1.7	0.9	1.5	1.4	1.1	1.1	1.4
Intelligence (Savage-Jansen 2018)	1.2	3.6	6.5	-1.7	-2.0	-1.7	-2.0	-2.1	-1.5	-1.8	-0.1	-1.9	-2.0	-1.9	-2.2	-1.8	-1.3	-2.0	-2.5	-2.1
High blood pressure (siblings)	1.2	1.7	3.1	-0.7	-1.1	-1.3	-1.4	-1.5	-1.1	-1.8	-1.1	-1.0	-1.5	-1.0	-1.4	-1.3	-1.6	-1.5	-1.2	-1.1
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.3	0.8	0.9	1.2	1.2	1.5	0.8	1.3	1.3	1.2	1.3	1.1	1.3	1.3	1.0	1.3	0.8	1.1
Hearing difficulty/problems: Yes	1.1	1.7	2.9	1.5	1.4	1.2	1.5	1.3	1.7	1.0	0.3	1.3	1.3	1.0	1.6	1.4	1.5	1.5	0.8	1.2
Hand grip strength (right)	1.1	3.0	5.7	-0.8	-1.7	-2.2	-1.7	-2.2	-1.7	-0.2	-2.1	-1.3	-1.3	-1.8	-1.9	-1.4	-1.5	-2.0	-2.4	-1.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	3.5	-1.3	-0.6	-0.8	-1.2	-0.6	-1.0	-1.9	-0.6	-1.6	-1.2	-0.9	-1.2	-1.5	-1.3	-1.2	-0.4	-0.8
Alzheimer’s Disease (including proxy)	1.0	1.4	4.3	-1.5	-0.8	-1.0	-1.2	-1.3	-1.1	-2.1	-1.2	-1.0	-0.5	-0.7	-0.9	-1.4	-1.7	-1.1	-0.4	-1.2
Verbal and Numeric Reasoning (VNR)	1.0	2.5	4.5	-1.0	-1.8	-1.5	-1.9	-2.0	-1.3	-1.0	-0.3	-1.6	-1.6	-1.7	-2.1	-1.4	-1.0	-2.0	-2.0	-1.6
Chronic bronchitis/emphysema (father)	1.0	1.2	2.3	-1.3	-0.9	-1.0	-1.1	-0.7	-1.2	-1.1	-0.5	-1.5	-1.1	-1.1	-1.4	-1.2	-0.7	-1.3	-0.9	-0.7
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.0	-2.0	-1.7	-1.4	-1.3	-1.5	-1.4	-1.6	-0.8	-1.3	-1.4	-1.6	-1.2	-1.5	-1.2	-1.1	-1.8	-1.9
Medication: Ventolin 100micrograms inhaler	1.0	1.2	3.4	1.8	1.2	1.1	0.7	0.9	1.1	1.6	1.2	0.4	0.3	0.6	0.2	1.0	1.6	0.5	1.1	1.8
Qualifications: College or University degree	1.0	3.3	4.7	-2.2	-2.1	-1.9	-1.7	-1.8	-2.0	-1.3	-1.5	-1.7	-1.5	-1.9	-1.7	-1.7	-1.7	-1.7	-2.1	-2.1
Medication: Omeprazole	1.0	1.2	2.3	-0.8	-1.0	-1.2	-1.5	-1.1	-1.5	-0.7	-0.6	-1.2	-1.4	-0.9	-1.4	-1.1	-1.3	-1.4	0.0	-0.6
Number of full sisters	1.0	1.2	3.3	0.9	1.4	1.4	0.9	1.4	1.2	-0.0	1.8	0.4	0.4	1.1	0.6	0.6	0.9	0.8	1.5	1.3
Arm fat mass (left)	1.0	4.1	12.7	3.6	2.2	2.0	1.2	0.9	2.1	2.3	1.4	1.8	1.2	2.5	1.0	2.5	1.7	1.0	2.2	2.7
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.4	-1.1	-1.1	-1.1	-1.1	-1.3	-1.1	-0.8	-1.6	-1.1	-0.8	-1.1	-1.2	-1.3	-1.3	-1.3	-0.4	-1.1
Major Depression (MDD)	0.9	1.1	2.5	-0.9	-1.0	-0.9	-1.2	-1.1	-0.9	-1.6	0.7	-0.8	-1.2	-0.8	-0.8	-1.2	-1.2	-0.9	-1.0	-1.3
Lung FVC	0.9	4.8	7.4	-2.2	-2.5	-2.7	-2.2	-2.3	-2.3	-1.5	-1.8	-2.1	-2.0	-2.7	-1.7	-2.3	-2.1	-2.0	-2.0	-2.5
Father’s age at death	0.9	1.2	3.1	0.4	0.7	1.4	1.2	1.3	1.0	0.3	1.7	1.3	1.1	1.1	1.4	1.1	0.7	1.4	0.9	0.7
Blood clot in the leg (DVT)	0.9	1.2	2.8	-1.1	-1.1	-1.1	-1.0	-1.4	-1.1	-0.7	-1.7	-0.9	-0.6	-1.0	-1.1	-1.2	-1.3	-1.2	-0.5	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	4.4	-0.3	-1.1	-1.5	-1.8	-1.4	-1.3	-1.1	-1.0	-1.5	-2.1	-1.4	-1.7	-1.4	-1.7	-1.8	-0.6	-0.8
Mean Putamen Volume	0.8	0.9	3.2	0.0	0.8	1.1	0.9	1.2	0.6	0.4	1.2	0.9	0.6	0.9	1.0	0.4	0.9	1.1	1.8	0.7
Heart attack	0.8	1.0	4.9	0.1	-0.4	-0.3	-0.8	-1.1	-0.2	-2.2	-1.3	-0.4	-1.2	0.0	-1.4	-0.6	-1.1	-1.3	-0.9	-0.5
Depression (self-reported)	0.8	1.0	2.5	0.0	-0.7	-0.6	-1.1	-1.6	-0.9	-1.3	-0.0	-0.0	-1.3	-0.4	-1.5	-1.0	-0.8	-1.5	-1.1	-0.7
Arm fat mass (right)	0.8	3.2	11.2	3.3	1.9	1.8	0.9	0.5	1.9	2.0	1.0	1.6	1.0	2.3	0.7	2.2	1.4	0.7	2.0	2.3
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.1	-1.3	-1.0	-0.8	-0.9	-0.9	-1.0	-1.5	0.5	-0.6	-1.1	-0.8	-1.1	-1.2	-0.8	-0.8	-0.7	-1.2
Medication for pain relief, constipation, heartburn	0.8	1.4	3.3	0.9	1.2	1.0	1.2	1.4	1.3	1.1	1.8	0.9	1.1	0.9	1.5	1.1	0.9	1.4	0.6	1.1
Migraine (self-reported)	0.8	1.0	2.9	1.7	1.2	1.0	0.7	0.6	1.2	0.3	1.5	0.8	0.4	0.9	0.5	0.9	1.1	0.5	1.0	1.3
Leg fat percentage (left)	0.8	2.9	9.0	3.0	1.8	1.7	1.0	0.4	1.6	2.1	1.3	1.6	1.2	2.1	0.8	2.1	1.4	0.8	1.6	2.2
Blood Eosinophil Count	0.7	5.0	7.8	-2.5	-2.0	-2.3	-2.4	-1.5	-2.5	-2.3	-0.9	-2.7	-2.6	-2.4	-2.2	-2.8	-2.4	-2.4	-0.9	-2.1
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.1	0.4	1.0	1.8	1.3	1.0	1.3	0.0	-0.0	1.4	1.2	1.7	1.2	1.3	0.9	1.3	0.6	0.9
Trunk fat percentage	0.7	2.8	9.1	3.0	2.0	1.9	0.7	0.6	1.7	1.0	2.4	1.1	0.6	2.2	0.3	1.9	1.0	0.4	1.9	2.4
Fed-up feelings	0.7	1.2	3.0	1.7	1.5	1.2	0.8	0.9	0.9	0.5	1.1	0.9	0.3	1.2	0.4	0.8	1.1	0.5	1.7	1.6
Hayfever, allergic rhinitis or eczema	0.7	1.5	4.5	1.4	1.7	1.4	1.1	0.9	1.3	0.3	2.1	1.0	0.7	1.4	0.6	0.9	1.5	0.7	0.9	1.4
Waist circumference	0.7	2.4	7.3	2.7	1.6	1.7	0.9	0.5	1.7	1.6	0.8	1.6	1.0	2.2	0.6	2.0	1.3	0.7	1.6	2.0
Allergy	0.7	1.7	4.4	-1.6	-1.6	-1.4	-1.2	-0.9	-1.3	-0.8	-2.1	-1.2	-0.9	-1.6	-0.7	-1.2	-1.5	-0.8	-1.0	-1.4
Number of live births	0.7	1.0	2.6	1.3	0.9	0.7	1.1	0.7	0.9	1.2	0.7	1.6	1.0	1.2	1.1	1.1	1.0	1.0	0.2	0.8
Happiness	0.7	0.9	2.6	-0.1	-0.3	-0.5	-1.1	-0.8	-0.5	-1.6	0.3	-1.1	-1.4	-0.7	-1.6	-1.0	-0.7	-1.3	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	4.0	1.9	1.4	1.1	1.5	1.5	1.5	1.9	1.3	1.5	1.2	1.0	2.0	1.6	1.5	1.8	1.3	1.5
Smoking status: Previous	0.7	1.1	2.5	1.3	1.2	0.9	0.9	0.9	1.0	1.5	0.6	0.6	1.1	1.0	0.7	1.1	0.9	0.8	1.2	1.6
Average weekly red wine intake	0.7	1.0	3.1	-0.7	-0.9	-0.6	-1.1	-1.2	-0.7	-1.8	0.5	-0.4	-1.2	-0.4	-1.1	-0.8	-1.1	-0.9	-1.4	-1.0
Wears glasses or contact lenses	0.7	0.8	1.8	0.4	0.6	1.2	1.0	0.8	0.8	0.5	0.8	1.3	1.2	1.2	1.1	1.0	0.8	0.9	0.5	0.6
Age started oral contraceptive pill	0.7	0.9	1.5	1.1	1.0	0.9	1.1	1.1	1.2	0.3	0.4	1.0	0.8	0.9	1.1	0.8	0.8	1.0	0.8	1.0
Commuting to job workplace: Cycle	0.7	0.9	1.7	-0.7	-0.8	-1.0	-1.0	-1.0	-1.0	-1.2	0.0	-0.5	-1.3	-1.0	-1.0	-1.2	-0.9	-1.0	-0.7	-0.9
Pain experienced in last month	0.7	1.1	4.6	-0.7	-1.1	-1.0	-1.0	-1.5	-0.8	-0.8	-2.1	-0.6	-0.8	-0.5	-0.9	-0.5	-1.2	-0.9	-1.3	-1.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.2	0.1	-0.4	-0.3	-0.7	-1.0	-0.1	-2.0	-1.4	-0.4	-1.1	0.0	-1.3	-0.6	-1.0	-1.2	-0.8	-0.4
Schizophrenia vs Biploar Disorder	0.6	0.7	1.5	-0.6	-0.9	0.0	-0.9	-1.2	-0.7	-0.4	-1.0	-0.8	-0.6	-1.0	-0.9	-0.8	-0.7	-1.0	-1.2	-1.0
Smoking Status	0.6	1.5	2.2	1.4	1.4	1.2	1.4	1.5	1.4	1.1	0.9	1.0	1.2	1.0	1.0	1.1	1.5	1.1	1.0	1.5
Medication: Metformin	0.6	0.9	1.9	0.4	0.8	1.4	1.1	1.3	1.0	0.3	0.0	0.8	1.0	1.1	1.1	1.1	0.6	1.1	0.5	1.1
Serious illness, injury or assault to yourself	0.6	0.8	1.9	-0.3	-0.6	-0.7	-0.9	-0.6	-0.7	-1.3	-0.2	-0.8	-1.2	-0.9	-1.4	-1.0	-0.8	-1.3	-0.7	-0.5
Nervous feelings	0.6	1.0	1.9	-0.8	-0.6	-1.1	-1.1	-0.8	-0.8	-1.3	-0.2	-1.4	-1.3	-1.2	-0.9	-1.3	-1.1	-1.1	-0.5	-0.8
Impedance of arm (left)	0.6	2.9	14.4	-2.0	-0.7	-0.6	-1.2	-0.3	-1.1	-3.8	2.0	-1.5	-1.8	-1.0	-1.6	-2.2	-2.0	-1.4	-1.2	-1.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.8	-0.8	-1.0	-0.9	-0.8	-1.0	-1.0	-0.7	-1.3	-0.4	-0.7	-0.6	-0.7	-0.8	-1.0	-0.8	-0.9	-0.9
Body fat percentage	0.6	2.4	8.0	2.8	1.8	1.7	0.6	0.5	1.6	1.1	2.1	1.1	0.6	2.0	0.3	1.8	1.0	0.4	1.7	2.2
Leg fat percentage (right)	0.6	2.2	7.8	2.8	1.6	1.5	0.7	0.2	1.4	1.7	1.2	1.4	1.0	2.0	0.4	1.8	1.3	0.5	1.4	1.9
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.5	0.8	1.0	0.9	0.9	0.7	0.9	0.9	0.8	0.6	0.8	0.8	0.8	0.9	1.2	0.8	1.2	1.0
Fractured/broken bones in last 5 years	0.6	0.8	4.1	2.0	0.3	0.2	0.2	-0.9	0.8	1.5	-0.7	1.1	0.3	0.5	0.3	1.3	0.8	0.2	-0.0	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	2.2	-1.1	-0.4	-0.6	-0.6	-0.3	-0.7	-1.5	-0.6	-0.6	-0.7	-0.5	-0.5	-1.1	-1.0	-0.7	-0.1	-0.8
Blood Red Count	0.5	4.4	6.2	1.8	2.0	2.4	2.2	2.1	2.4	1.5	1.1	2.3	2.1	2.0	2.3	2.4	2.0	2.5	2.0	2.0
Sensitivity / hurt feelings	0.5	0.9	2.0	-1.1	-0.7	-1.1	-0.9	-0.7	-0.8	-1.3	-0.1	-1.4	-1.2	-1.0	-0.8	-1.1	-1.0	-0.9	-0.6	-1.0
Vitamin and mineral supplements	0.5	0.6	1.7	-0.4	-0.6	-0.8	-1.1	-1.0	-1.3	-0.2	-0.6	-0.6	-1.0	-0.3	-0.9	-0.7	-1.2	-0.9	0.1	-0.3
Medication: Co-codamol	0.5	0.6	2.3	0.5	0.2	0.3	0.6	-0.0	0.5	1.5	-1.0	0.6	1.0	0.4	1.0	1.0	0.9	0.9	0.1	0.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.0	0.6	0.7	0.9	0.8	0.5	0.9	0.3	0.7	1.0	0.9	0.7	0.8	0.6	0.7	0.8	0.6	0.6
Supplements: Glucosamine	0.5	0.6	1.7	0.2	0.5	0.5	0.7	1.3	0.6	0.9	1.2	0.1	0.8	0.3	0.9	0.7	0.8	0.9	1.1	0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	5.5	-0.3	-0.8	-0.9	-0.5	-0.9	-0.6	0.9	-2.3	-0.4	-0.0	-0.8	-0.3	-0.2	-0.1	-0.4	-0.5	-0.5
Body mass index (BMI)	0.5	2.2	7.7	2.8	1.4	1.2	0.7	0.3	1.4	2.4	-0.0	1.1	1.0	1.7	0.6	2.0	1.3	0.5	1.7	1.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.3	1.8	0.7	0.5	-0.0	-0.4	0.8	0.2	0.4	1.0	-0.1	1.3	0.3	1.0	-0.2	0.1	0.7	0.8
Overall health rating	0.5	1.2	4.6	-0.4	-0.5	-0.4	-1.2	-0.9	-0.6	-2.1	-0.2	-1.0	-1.6	-0.6	-1.6	-1.2	-1.4	-1.5	-0.2	-0.5
Ulcerative Colitis (UC)	0.4	0.8	2.7	-0.3	-0.8	-0.8	-0.9	-0.9	-0.8	0.3	-1.6	-1.1	-0.9	-1.0	-0.9	-0.6	-0.7	-1.0	-0.7	-0.4
Fasting Glucose	0.4	0.5	3.4	-0.2	-0.4	-0.7	-0.6	0.0	-0.6	-0.6	-1.8	-0.6	-0.7	-0.5	-0.6	-0.7	-0.8	-0.6	-0.5	-0.3
Angina	0.4	0.5	2.5	1.6	0.8	0.8	0.0	-0.3	0.8	-0.7	0.2	0.6	-0.3	0.9	-0.6	0.4	0.1	-0.5	0.4	0.8
Pain all over the body in last month	0.4	0.5	1.3	-0.5	-0.7	-0.7	-0.6	-0.6	-0.5	-0.4	0.4	-0.8	-0.5	-1.1	-0.7	-0.8	-0.4	-0.6	-1.0	-0.7
Diabetes (self-reported)	0.4	0.7	1.9	0.2	0.8	1.4	0.9	1.1	1.0	-0.5	0.1	0.8	0.7	1.1	0.9	0.7	0.5	0.9	0.4	0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	0.6	1.0	0.5	0.7	1.2	0.6	-0.3	1.2	0.4	0.3	0.7	0.6	0.1	0.2	0.4	0.8	0.8
Hair/balding pattern: Pattern 3	0.4	0.7	2.2	0.3	-0.9	-1.1	-0.9	-1.5	-0.6	-0.0	-1.0	-0.0	-0.6	-0.7	-0.8	-0.4	-0.7	-1.0	-1.1	-0.7
Tense / ‘highly strung’	0.4	0.7	1.7	0.1	-0.6	-0.8	-1.1	-1.0	-0.6	-0.9	-1.2	-0.6	-1.3	-0.8	-0.9	-0.8	-0.9	-1.0	-0.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.7	0.3	0.9	0.6	0.5	1.0	0.3	-0.1	1.6	0.3	0.2	0.6	0.1	-0.1	0.4	0.3	1.4	0.7
Headache pain in last month	0.4	0.6	2.5	0.8	1.1	0.7	0.7	0.9	0.7	-0.1	1.6	0.7	0.2	0.6	0.7	0.4	0.8	0.7	0.5	0.8
Gout (self-reported)	0.4	0.5	2.4	-1.6	-0.7	-0.6	-0.3	-0.3	-0.7	-1.2	-0.8	-0.2	-0.4	-0.4	-0.2	-0.9	-0.5	-0.2	-0.1	-1.1
Neck or shoulder pain in last month	0.4	0.5	1.6	1.2	1.0	0.6	0.5	1.0	0.8	0.3	1.3	0.3	0.1	0.5	0.2	0.4	0.7	0.4	0.8	1.1
Angina (self-reported)	0.4	0.6	3.1	1.8	0.9	0.9	0.2	-0.2	1.0	-0.5	0.4	0.7	-0.1	1.0	-0.5	0.6	0.3	-0.3	0.6	1.0
Medication: Allopurinol	0.4	0.5	1.5	-1.2	-0.8	-0.8	-0.5	-0.6	-0.8	-0.4	-1.2	-0.5	-0.3	-0.9	-0.5	-0.9	-0.2	-0.4	-0.1	-0.9
Heart disease (mother)	0.4	0.4	1.7	-0.5	-0.6	-0.6	-0.7	-0.9	-0.8	-0.3	-1.3	-0.5	-0.6	-0.6	-0.7	-0.6	-0.7	-0.6	-0.1	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.8	-0.7	0.5	0.5	0.8	1.3	0.3	-0.0	0.6	-0.1	0.5	-0.2	0.8	-0.1	0.6	0.9	1.1	0.4
Eye problems/disorders: Glaucoma	0.4	0.5	1.3	0.0	0.5	0.7	0.9	1.1	0.6	0.3	0.6	0.8	0.9	0.9	1.1	0.7	0.4	1.0	0.5	0.3
Impedance of whole body	0.4	2.2	10.2	-1.7	-0.5	-0.4	-1.1	-0.3	-1.1	-3.2	2.3	-1.2	-1.5	-0.8	-1.4	-1.8	-1.6	-1.1	-1.1	-1.1
Neuroticism (Nagel 2018)	0.3	0.6	2.0	0.1	-0.3	-0.7	-1.0	-1.1	-0.5	-1.2	-0.3	-0.8	-1.4	-0.5	-1.1	-0.7	-0.7	-1.0	0.0	-0.3
Rheumatoid Arthritis	0.3	0.3	1.2	1.1	0.7	0.5	0.4	0.4	1.0	-0.4	1.1	0.3	-0.2	0.4	0.2	0.5	0.3	0.3	-0.2	0.6
Heel T-Score	0.3	2.4	4.0	0.6	1.3	1.8	1.7	1.5	1.5	1.4	0.6	1.4	1.9	1.6	2.0	1.7	1.4	1.8	2.0	1.3
BMI	0.3	2.0	5.2	2.3	1.4	1.4	0.9	0.8	1.4	1.8	0.1	0.9	1.0	1.6	0.7	1.8	1.4	0.7	2.0	1.9
Allergy or Eczema	0.3	0.8	3.0	1.4	1.2	0.8	0.5	0.1	0.8	0.2	1.7	0.6	-0.1	1.1	-0.1	0.7	1.2	0.2	0.3	1.0
Hair Pigment	0.3	7.8	9.5	2.8	2.6	2.8	2.8	2.3	2.8	2.8	2.8	3.1	3.0	3.0	2.8	3.0	2.8	3.0	2.4	2.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	0.9	0.7	0.6	0.3	-0.1	0.4	0.4	-0.1	0.4	0.3	0.9	-0.1	0.5	0.5	0.0	1.3	0.8
Impedance of leg (right)	0.3	1.5	4.7	-1.4	-0.7	-0.5	-1.1	-0.9	-1.2	-2.2	1.5	-0.8	-1.2	-0.7	-1.2	-1.4	-1.2	-0.9	-1.4	-1.2
Maternal smoking around birth	0.3	0.4	1.7	-0.5	-0.8	-0.6	-0.5	-0.0	-0.7	0.2	-1.3	-0.8	-0.4	-1.0	-0.4	-0.5	-0.8	-0.5	-0.7	-0.3
Qualifications: None of the above	0.3	0.6	1.3	0.7	0.9	1.0	0.8	0.9	0.8	0.5	0.5	0.7	0.8	0.8	0.8	0.6	0.5	0.7	1.1	1.0
Noisy workplace	0.3	0.3	2.3	-0.1	0.7	0.2	0.5	0.9	0.4	0.0	0.2	0.0	0.5	0.2	0.8	-0.1	-0.1	0.5	1.5	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	-0.3	0.5	0.8	0.7	0.5	0.4	-0.3	1.2	0.7	0.4	0.7	0.6	0.2	0.5	0.8	1.1	0.2
Prospective memory result	0.3	0.4	1.5	-0.3	0.0	-0.2	0.6	0.8	0.0	1.2	-0.9	0.0	0.9	-0.2	1.1	0.5	0.2	0.8	-0.0	0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.8	-0.6	-0.9	-0.6	-0.7	-0.7	-0.7	-0.7	-0.6	-0.5	-0.8	-0.4	-0.5	-0.3	-0.6	-0.4	-0.9	-0.9
Eye problems/disorders: None of the above	0.3	0.3	0.7	0.7	0.6	0.4	0.4	-0.1	0.8	0.6	0.4	0.4	0.5	0.5	0.7	0.8	0.8	0.6	0.2	0.4
Medication: Ibuprofen	0.3	0.3	1.5	-1.2	-0.4	0.1	-0.1	-0.3	-0.5	-1.2	1.0	0.0	-0.4	0.0	-0.2	-0.7	-0.3	-0.1	0.1	-0.8
Suffer from ‘nerves’	0.3	0.4	1.2	1.1	0.7	0.4	0.5	0.2	0.7	0.3	-0.3	0.9	0.2	0.6	0.9	0.7	0.7	0.7	0.7	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.5	-0.3	0.2	0.3	0.9	0.5	0.2	0.9	0.3	0.7	1.2	0.2	1.0	0.5	0.6	0.9	-0.0	0.1
Arm fat percentage (left)	0.3	1.3	5.4	2.3	1.3	1.2	0.3	0.1	1.1	0.8	1.3	0.7	0.3	1.6	-0.1	1.3	0.6	-0.0	1.2	1.6
Diabetes diagnosed by doctor	0.3	0.5	1.5	0.4	0.8	1.2	0.7	0.9	0.9	-0.7	-0.4	0.7	0.4	1.0	0.6	0.7	0.2	0.6	0.4	0.8
Commuting to job workplace: Walk	0.3	0.4	1.2	-0.8	-0.6	-0.9	-0.2	-0.3	-0.6	0.7	-1.0	-0.5	-0.1	-1.1	0.1	-0.4	0.3	0.1	-0.3	-0.6
Risk taking	0.3	0.4	1.7	-0.8	-0.8	-0.7	-0.6	-0.2	-0.6	0.4	-1.3	-0.7	-0.2	-0.8	0.0	-0.3	-0.6	-0.2	-0.3	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	0.6	0.7	0.8	0.4	-0.2	0.5	0.1	0.7	0.8	0.6	1.1	0.3	0.6	0.6	0.5	0.6	0.4
Supplements: Calcium	0.3	0.4	0.9	-0.7	-0.8	-0.8	-0.6	-0.7	-0.5	-0.0	0.4	-0.6	-0.3	-0.9	-0.5	-0.4	-0.3	-0.5	-0.8	-0.8
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	-1.0	-1.0	-0.6	-0.2	-0.3	-0.5	-0.2	-0.9	-0.1	0.1	-0.6	0.0	-0.4	-0.5	0.1	-1.1	-1.1
Depression (Nagel 2018)	0.2	0.3	0.9	0.7	-0.1	-0.2	-0.7	-0.9	-0.3	0.1	-0.9	-0.3	-0.8	0.3	-0.8	0.2	-0.4	-0.7	0.7	0.2
Reaction Time	0.2	0.4	2.2	-0.1	-0.1	-0.0	-0.6	-0.5	-0.1	-1.5	0.2	-0.5	-0.8	-0.2	-1.0	-0.6	-0.9	-1.0	0.3	-0.1
HDL Cholesterol	0.2	0.3	1.1	0.2	-0.2	0.0	0.2	-0.7	-0.1	1.0	-0.7	1.1	0.8	0.4	0.4	0.5	0.6	0.4	-0.2	-0.2
Ulcerative Colitis	0.2	0.4	0.8	-0.3	-0.2	-0.4	-0.6	-0.6	-0.4	-0.9	-0.2	-0.8	-0.7	-0.6	-0.9	-0.8	-0.4	-0.9	-0.4	-0.3
Blood White Count	0.2	1.7	4.1	-1.6	-1.0	-0.9	-1.4	-1.0	-1.6	-1.1	-1.1	-2.0	-1.5	-0.9	-1.8	-1.4	-0.9	-1.6	-0.4	-0.9
Neuroticism	0.2	0.4	1.8	0.3	-0.0	-0.3	-0.7	-0.7	-0.2	-1.4	0.4	-0.3	-1.1	0.1	-0.8	-0.4	-0.6	-0.7	-0.2	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.7	-0.1	0.2	0.4	0.7	0.5	0.3	0.5	-0.3	0.7	0.8	0.4	0.8	0.5	0.4	0.8	0.2	0.1
Supplements: Zinc	0.2	0.2	0.8	-0.9	-0.3	-0.4	0.1	0.3	-0.3	-0.2	-0.3	-0.6	0.0	-0.7	-0.0	-0.5	-0.3	0.0	0.0	-0.4
Taking other prescription medications	0.2	0.3	0.8	-0.9	-0.7	-0.3	-0.5	-0.1	-0.6	-0.9	-0.3	-0.3	-0.7	-0.4	-0.4	-0.5	-0.5	-0.4	-0.3	-0.6
Multivitamins +/- minerals	0.2	0.2	0.7	-0.3	0.2	0.4	0.9	0.3	0.8	-0.3	0.2	0.4	0.7	-0.0	0.4	0.2	0.8	0.6	-0.3	-0.3
Impedance of leg (left)	0.2	1.0	4.0	-1.1	-0.3	-0.2	-0.7	-0.4	-0.9	-2.0	1.9	-0.6	-0.9	-0.4	-0.8	-1.1	-1.0	-0.5	-1.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	1.0	0.4	0.4	0.2	-0.6	0.6	0.5	0.4	0.7	0.1	0.7	-0.1	0.5	0.7	0.0	0.5	0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.0	0.6	-0.4	-0.5	-0.8	-1.0	-0.2	-0.1	0.7	-0.1	-0.9	-0.4	-0.3	-0.2	-0.3	-0.4	-0.5	-0.3
Financial difficulties in last 2 years	0.2	0.2	0.7	0.8	0.4	0.4	-0.2	-0.2	0.3	-0.3	0.9	0.3	-0.5	0.3	-0.5	-0.1	0.5	-0.3	0.3	0.5
Arm fat percentage (right)	0.2	0.7	4.1	2.0	1.0	0.8	-0.1	-0.2	0.7	0.4	0.8	0.3	-0.1	1.3	-0.4	0.9	0.1	-0.4	0.9	1.3
Worrier / anxious feelings	0.2	0.3	1.7	0.1	0.3	-0.2	-0.3	0.2	-0.0	-1.2	1.3	-0.6	-0.9	-0.1	-0.4	-0.4	-0.2	-0.3	0.3	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	1.1	0.9	-0.2	-0.2	-0.3	-1.1	-0.1	0.9	0.0	0.7	-0.3	0.4	0.2	0.6	0.3	-0.0	-0.1	-0.0
Medication: Paracetamol	0.2	0.4	1.7	0.8	0.4	0.3	0.6	0.2	0.5	1.3	-0.5	0.6	0.8	0.2	0.4	0.7	1.1	0.5	0.1	0.6
Number of full brothers	0.2	0.3	1.6	0.9	0.5	0.2	0.2	-0.1	0.2	1.3	-0.1	0.3	0.4	0.5	-0.0	0.4	0.5	0.1	0.9	0.7
Worry too long after embarrassment	0.2	0.4	1.4	0.1	-0.2	-0.8	-0.7	-0.5	-0.3	-0.7	0.5	-0.9	-1.2	-0.7	-0.6	-0.6	-0.8	-0.7	-0.2	-0.3
Wheeze or whistling in the chest in last year	0.2	0.3	1.4	1.2	0.5	0.7	-0.1	-0.2	0.4	-0.2	0.9	0.4	-0.5	0.5	-0.8	0.1	0.6	-0.5	0.4	0.7
Health satisfaction	0.2	0.3	1.2	0.8	0.6	0.6	0.2	0.1	0.4	0.1	-0.5	0.3	0.3	0.7	0.0	0.4	0.1	-0.0	1.1	0.9
Shortness of breath walking on level ground	0.2	0.2	0.6	0.7	0.5	0.7	0.1	-0.3	0.5	-0.5	-0.6	0.2	0.2	0.7	-0.6	0.3	0.1	-0.3	0.3	0.6
Medication: Seretide 50 evohaler	0.2	0.2	0.8	0.3	-0.1	-0.7	-0.5	-0.3	-0.2	0.2	0.4	-0.5	-0.6	-0.9	-0.3	-0.5	-0.0	-0.5	-0.4	-0.2
Mean time to correctly identify matches	0.2	0.3	2.4	0.1	0.2	0.2	-0.3	-0.1	0.1	-1.5	-0.1	-0.2	-0.6	0.2	-0.6	-0.3	-0.8	-0.7	0.5	0.2
Had major operations	0.2	0.3	0.7	0.8	0.7	0.5	0.3	0.1	0.7	-0.3	0.6	0.6	0.0	0.8	0.3	0.4	0.1	0.4	0.6	0.5
Leg pain on walking	0.2	0.2	1.0	0.8	0.1	0.1	0.1	-0.8	0.5	0.4	-0.2	1.0	0.4	0.4	0.6	0.5	0.1	0.3	0.1	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	0.3	-0.1	-0.4	-0.7	-0.4	-0.7	-0.1	-0.7	-0.3	-0.7	0.1	-0.4	-0.3	-0.6	-0.6	0.7	0.3
Illnesses of father: Heart disease	0.2	0.3	0.6	0.1	-0.4	-0.5	-0.6	-0.8	-0.2	-0.8	-0.2	-0.5	-0.8	-0.3	-0.7	-0.2	-0.3	-0.7	-0.2	-0.4
Illnesses of siblings: Diabetes	0.2	0.2	2.0	0.1	0.2	0.5	-0.2	-0.4	0.1	-1.4	0.5	0.3	-0.5	0.5	-0.5	-0.4	-0.5	-0.4	-0.0	-0.0
Long-standing illness, disability or infirmity	0.2	0.4	1.3	0.2	-0.3	-0.4	-0.8	-0.5	-0.2	-0.7	-0.3	-1.0	-1.1	-0.5	-0.7	-0.5	-0.6	-0.9	-0.2	-0.1
Eye problems/disorders: Cataract	0.2	0.2	0.5	0.5	0.3	0.4	0.5	0.2	0.3	0.7	-0.5	0.5	0.7	0.4	0.0	0.5	0.3	0.0	0.3	0.5
Breast cancer (self-reported)	0.2	0.2	0.9	-1.0	-0.4	-0.4	0.1	0.8	-0.3	-0.6	-0.8	-0.2	0.1	-0.5	0.4	-0.5	-0.1	0.3	-0.2	-0.5
Hearing aid user	0.2	0.2	2.1	0.5	-0.1	-0.4	-0.1	-0.3	0.1	0.3	-1.4	0.2	-0.0	0.4	0.5	0.5	-0.1	0.2	-0.4	-0.0
Financial situation satisfaction	0.2	0.3	0.9	0.2	0.4	-0.0	-0.4	-0.1	-0.1	-1.0	-0.3	-0.4	-0.7	-0.1	-0.7	-0.7	-0.2	-0.6	0.9	0.3
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	-1.1	-0.5	-0.0	-0.1	-0.0	-0.5	-0.5	-0.1	-0.4	0.1	-0.3	-0.3	-0.4	-0.4	-0.2	-0.1	-0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.3	-0.5	-0.6	-0.8	-0.7	-0.3	-0.4	0.2	0.0	-1.2	-0.4	-1.0	-0.1	-0.4	-0.5	-0.2	-0.0	-0.5
Ever depressed for a whole week	0.2	0.3	1.1	0.2	-0.3	-0.4	-0.5	-1.1	-0.2	-0.5	0.8	-0.1	-0.5	-0.2	-0.6	-0.3	-0.4	-0.6	-0.6	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.5	-0.1	-0.3	-0.5	-0.7	-0.4	-0.7	-0.4	-0.2	-0.5	-0.7	-0.0	-0.7	-0.3	-0.6	-0.7	0.3	0.0
Heart disease (siblings)	0.2	0.2	0.8	0.8	0.5	0.2	-0.1	-0.5	0.3	0.2	-0.5	-0.1	-0.2	0.3	-0.5	0.3	0.4	-0.2	0.9	0.7
Depressed Affect (Nagel 2018)	0.1	0.2	1.4	1.2	0.6	0.4	0.1	-0.2	0.3	0.4	-0.2	0.2	-0.0	0.5	-0.2	0.5	0.4	-0.1	0.6	0.8
Worry (Nagel 2018)	0.1	0.1	0.8	0.5	0.5	0.1	-0.1	-0.2	0.2	-0.9	0.4	0.0	-0.6	0.2	-0.1	-0.1	0.0	-0.1	0.6	0.3
Alzheimer’s Disease (in father)	0.1	0.1	0.4	-0.0	0.1	0.2	0.2	-0.3	0.1	-0.1	-0.6	0.3	0.2	0.4	0.2	0.2	-0.0	0.2	0.5	0.1
Hand grip strength (left)	0.1	0.3	0.9	0.0	-0.4	-0.8	-0.5	-1.0	-0.5	0.2	-0.5	-0.1	-0.2	-0.4	-0.8	-0.4	-0.3	-0.8	-0.9	-0.4
Ever had hysterectomy (womb removed)	0.1	0.1	1.2	0.4	0.0	-0.1	-0.2	-0.1	0.1	0.1	-1.1	-0.1	-0.1	-0.0	-0.1	0.1	-0.3	-0.3	0.3	0.2
Townsend deprivation index at recruitment	0.1	0.2	0.5	-0.2	-0.1	-0.2	-0.4	-0.1	-0.2	-0.5	0.5	-0.6	-0.6	-0.7	-0.7	-0.7	0.0	-0.6	-0.1	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.8	0.7	-0.1	-0.3	-0.5	-0.9	-0.2	0.2	-0.7	-0.1	-0.7	0.1	-0.3	0.0	-0.2	-0.3	0.2	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.5	0.5	0.4	0.5	0.3	-0.1	0.3	0.1	-0.3	0.6	0.3	0.6	-0.1	0.3	0.4	0.1	0.7	0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.4	-0.5	-0.1	-0.1	0.1	0.5	0.0	0.4	-0.6	-0.5	0.2	-0.6	0.3	-0.2	-0.1	0.3	0.5	-0.2
Stomach or abdominal pain in last month	0.1	0.1	0.4	-0.2	0.3	0.1	0.0	-0.2	-0.1	-0.5	0.6	0.2	-0.0	0.3	-0.2	-0.3	0.0	-0.1	0.6	-0.1
Had other major operations	0.1	0.1	1.0	1.0	0.2	-0.2	-0.1	-0.1	0.3	0.4	-0.6	0.4	-0.3	0.3	0.2	0.3	-0.1	-0.0	0.4	0.3
Forced vital capacity (FVC)	0.1	0.4	1.5	0.7	0.3	0.2	0.6	0.5	0.7	1.2	0.8	0.5	0.6	0.0	1.1	0.8	0.8	0.9	0.2	0.4
Neuroticism score	0.1	0.2	0.8	0.9	0.7	0.2	-0.0	-0.1	0.4	-0.7	0.7	-0.0	-0.6	0.3	-0.2	0.0	-0.1	-0.2	0.3	0.5
Time employed in main current job	0.1	0.1	0.4	-0.1	-0.4	-0.5	0.1	-0.0	-0.1	0.6	0.1	0.2	0.4	0.0	0.4	0.3	-0.1	0.2	-0.5	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	-0.1	-0.1	-0.1	-0.5	-0.5	-0.3	-0.6	0.6	-0.7	-0.7	-0.3	-0.9	-0.4	-0.2	-0.6	-0.2	-0.1
Glaucoma (self-reported)	0.1	0.1	0.5	-0.7	-0.1	0.1	0.0	0.7	-0.1	-0.3	-0.3	-0.3	0.1	0.0	0.3	-0.2	-0.4	0.2	0.3	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.3	1.1	0.0	-0.7	-1.0	-0.5	-0.5	-0.5	0.6	0.0	-0.4	-0.6	-1.1	0.1	-0.2	-0.3	-0.2	-0.6	-0.5
Exposure to tobacco smoke outside home	0.1	0.2	0.9	0.2	0.5	-0.2	0.1	0.6	0.0	0.0	0.7	-0.1	-0.1	-0.0	0.6	-0.2	-0.1	0.3	1.0	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.5	-0.1	-0.4	-0.2	-0.3	-0.2	0.5	0.1	0.4	-0.2	-0.1	0.3	0.1	-0.1	0.1	-0.2	0.0
Knee pain experienced in last month	0.1	0.2	0.4	-0.3	0.2	0.5	0.6	0.6	0.3	-0.2	0.4	0.6	0.6	0.1	0.4	-0.1	0.3	0.4	0.5	0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	0.4	0.3	0.0	0.2	-0.2	0.3	-0.1	-0.4	0.5	0.2	0.4	0.2	0.3	0.3	0.1	0.3	0.2
Mood swings	0.1	0.2	0.6	0.8	0.4	0.5	0.2	-0.1	0.2	0.5	-0.3	0.3	0.1	0.5	0.1	0.5	0.4	0.1	0.5	0.5
Loneliness, isolation	0.1	0.1	0.3	0.2	0.3	0.3	0.4	0.2	0.3	0.3	0.3	0.5	0.4	0.4	0.3	0.2	0.5	0.4	0.4	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.3	-0.3	-0.4	-0.4	-0.6	0.0	-0.1	-0.4	0.1	-0.4	0.0	0.1	0.1	-0.5	-0.1	-0.1	-0.3
Mineral and other dietary supplements	0.1	0.2	0.7	0.8	0.6	0.4	0.2	-0.3	0.1	-0.3	-0.5	0.8	0.1	0.8	-0.2	0.1	0.1	-0.2	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	-0.8	-0.4	-0.5	-0.3	-0.3	-0.6	-0.3	0.3	-0.2	-0.5	-0.5	0.3	-0.5	-0.2	0.1	-0.2	-0.7
Miserableness	0.1	0.1	0.2	0.1	-0.0	-0.4	-0.3	0.0	-0.3	0.1	-0.4	-0.5	-0.5	-0.4	-0.3	-0.3	-0.2	-0.3	-0.2	0.1
Commuting to job workplace: Public transport	0.1	0.1	0.6	0.3	-0.0	-0.1	-0.0	-0.8	0.5	-0.2	-0.6	0.3	-0.1	0.2	-0.1	0.2	0.2	-0.0	-0.5	-0.3
Medication: Paracetamol	0.1	0.2	1.3	-0.1	-0.5	-0.4	-0.2	-0.5	-0.4	0.5	-1.2	-0.2	-0.0	-0.5	-0.4	-0.1	0.2	-0.3	-0.7	-0.2
Alcohol drinker status: Never	0.1	0.1	0.3	0.3	0.2	0.2	0.3	-0.4	0.3	0.2	-0.5	0.5	0.4	0.3	0.3	0.5	0.5	0.3	-0.2	0.1
Number of operations (self-reported)	0.1	0.1	0.9	0.4	-0.1	-0.1	0.0	-0.1	0.3	0.7	-0.9	0.5	0.2	0.1	0.5	0.3	0.3	0.4	-0.0	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.4	0.7	-0.3	-0.6	-0.9	-0.8	-0.5	-0.8	-0.4	-0.0	-0.4	-0.8	-0.7	-0.8	-0.6	-0.5	-0.7	-0.5	-0.6
Pack years adult smoking proportion	0.0	0.1	0.3	-0.1	-0.2	0.2	-0.0	-0.1	-0.1	-0.3	0.5	0.6	-0.1	0.2	-0.0	-0.1	0.0	0.1	-0.2	-0.3
Hearing difficulty/problems with background noise	0.0	0.0	0.1	0.3	0.1	-0.3	-0.1	-0.1	-0.1	0.0	-0.3	-0.2	-0.3	-0.0	-0.1	-0.2	-0.2	-0.2	0.3	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.2	0.0	0.0	0.2	0.2	-0.1	-0.0	0.3	-0.5	0.2	0.4	0.1	-0.1	0.1	0.2	-0.0	0.3	0.2
Lung cancer (father)	0.0	0.0	0.2	0.1	0.2	-0.2	-0.0	0.2	-0.2	0.1	0.4	-0.0	0.0	-0.2	-0.2	-0.4	0.0	-0.0	0.1	0.1
Irritability	0.0	0.1	0.3	-0.2	-0.2	-0.0	-0.2	-0.3	-0.2	-0.5	-0.5	0.0	-0.4	-0.0	0.0	-0.0	-0.5	-0.1	-0.2	-0.2
Pack years of smoking	0.0	0.1	0.4	0.0	-0.0	0.3	0.1	0.0	0.0	-0.2	0.6	0.6	0.1	0.4	0.2	0.2	0.1	0.2	-0.0	-0.1

Hub : Genes

FUT2

Models

Trait associations