TWAS hub - SEC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0460	0.0152	1.6e-09	0.047	0.054	0.055	NA	0.051	5.2e-10	3.0e-11	2.2e-11	NA	8.9e-11
2	TCGA	Colon Adenocarcinoma	0.0500	0.0290	7.6e-03	0.040	-0.005	0.010	NA	0.000	2.3e-03	8.4e-01	8.5e-02	NA	3.4e-01
3	TCGA	Glioblastoma Multiforme	0.2570	0.0970	1.1e-03	-0.009	0.067	0.019	NA	0.011	8.7e-01	4.3e-03	8.3e-02	NA	1.5e-01
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.1430	0.0455	4.1e-10	0.134	0.101	0.123	NA	0.131	7.7e-15	1.8e-11	1.1e-13	NA	1.6e-14
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1160	0.0500	1.1e-03	0.052	0.067	0.047	NA	0.054	6.3e-04	1.1e-04	1.1e-03	NA	4.7e-04
6	TCGA	Brain Lower Grade Glioma	0.1579	0.0483	6.8e-12	0.112	0.098	0.069	NA	0.109	1.2e-12	3.4e-11	2.5e-08	NA	2.1e-12
7	TCGA	Ovarian Serous Cystadenocarcinoma	0.1860	0.0710	4.2e-04	0.057	0.049	0.050	NA	0.042	1.0e-04	2.9e-04	2.8e-04	NA	8.2e-04
8	TCGA	Prostate Adenocarcinoma	0.0566	0.0240	2.6e-04	0.054	0.045	0.055	NA	0.050	2.6e-06	1.6e-05	1.8e-06	NA	5.6e-06
9	TCGA	Soft Tissue Sarcoma	0.3070	0.0860	4.0e-08	0.166	0.171	0.169	NA	0.174	4.3e-10	2.1e-10	2.7e-10	NA	1.4e-10
10	TCGA	Thyroid Carcinoma	0.2340	0.0550	1.5e-14	0.152	0.144	0.138	NA	0.140	1.2e-14	6.7e-14	2.6e-13	NA	1.5e-13

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
High cholesterol (Self-reported)	7.1	12.5	47.9	3.2	-6.9	2.6	3.3	2.2	4.4	0.6	3.3	2.4	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	6.7	8.7	14.4	-3.6	-0.4	-2.3	-3.8	-3.3	-3.3	-0.4	-3.5	-2.9	-3.3
Bilateral oophorectomy (both ovaries removed)	6.5	7.5	10.6	2.3	-1.7	2.5	3.0	2.3	3.0	2.6	3.0	3.3	3.3
Alcohol intake frequency.	6.4	14.8	29.2	-3.8	5.4	-2.6	-4.0	-3.1	-5.0	-1.7	-4.2	-4.0	-3.2
Ever used hormone-replacement therapy (HRT)	5.6	7.2	15.2	-3.9	0.7	-3.1	-2.8	-2.9	-2.8	-0.1	-3.0	-2.7	-2.6
Medication: Simvastatin	5.4	7.9	28.3	1.9	-5.3	2.1	2.4	1.6	3.0	2.6	2.4	2.3	2.7
Peak expiratory flow (PEF)	5.3	12.2	25.4	-3.3	5.0	-4.0	-2.6	-3.7	-3.6	-2.3	-3.0	-3.0	-3.6
LDL Cholesterol	5.2	8.2	20.6	0.0	-4.3	4.5	0.0	3.8	4.3	0.0	0.0	0.0	3.2
Waist Hip Ratio (WHR)	5.1	23.0	30.0	5.0	-5.5	4.2	4.6	4.8	5.5	4.5	4.8	4.6	4.4
Comparative height size at age 10	4.9	27.1	40.3	-5.3	4.8	-4.7	-5.9	-5.0	-6.4	-2.9	-5.9	-5.4	-5.0
Blood White Count	4.8	35.4	50.0	6.2	-1.2	4.8	7.1	6.1	6.7	4.5	7.0	7.0	6.3
Age when periods started (menarche)	4.7	11.2	19.2	4.4	-3.3	3.2	3.4	3.2	4.1	0.2	3.7	3.2	3.1
Fractured/broken bones in last 5 years	4.5	5.7	11.2	-2.0	0.7	-2.3	-2.4	-2.0	-2.6	-3.3	-2.7	-3.3	-1.3
Serious illness, injury or assault of a close relative in last 2 years	4.3	4.9	15.4	2.0	-3.9	2.9	1.4	1.8	2.1	0.5	1.6	1.5	2.5
Alcohol drinker status: Previous	4.0	4.5	7.2	-2.2	2.7	-1.3	-1.9	-1.9	-2.6	-1.9	-2.3	-2.5	-1.5
Hypothyroidism (self reported)	3.9	8.9	23.5	2.9	-4.8	2.8	2.5	2.7	3.4	2.4	2.7	2.5	2.5
Prospective memory result	3.8	4.7	11.1	-2.6	0.9	-1.8	-2.0	-1.5	-2.1	-1.6	-2.3	-2.6	-3.3
Comparative body size at age 10	3.8	10.4	18.7	-4.0	4.3	-2.0	-3.2	-2.9	-4.0	-0.2	-3.5	-3.0	-3.2
Cholesterol lowering medication	3.5	5.1	20.3	2.3	-4.5	1.9	1.9	1.6	2.3	-0.1	1.8	1.1	2.5
Lupus	3.1	4.7	9.0	-1.3	3.0	-2.7	-2.0	-1.7	-2.6	-1.6	-2.1	-2.2	-1.8
Medication: Cholesterol lowering	3.1	4.8	25.0	0.9	-5.0	1.6	1.6	1.0	2.2	2.0	1.4	1.2	2.1
Crohns Disease (2017)	3.0	6.5	25.4	2.3	-5.0	2.9	0.0	2.1	3.0	1.0	2.2	2.0	1.7
Forced expiratory volume in 1-second (FEV1)	3.0	10.0	13.5	-3.6	2.5	-3.3	-2.9	-3.7	-3.5	-1.9	-3.3	-3.2	-3.3
Hypothyroidism/myxoedema (self-reported)	3.0	5.9	11.8	2.7	-3.4	1.9	2.4	2.3	3.0	0.7	2.5	2.2	2.1
Cardiovascular Disease	2.9	9.7	65.8	0.8	-8.1	1.9	2.0	0.8	2.9	2.4	1.6	1.1	2.0
Average weekly spirits intake	2.9	3.6	10.3	-1.8	3.2	-2.2	-1.5	-2.1	-2.2	0.2	-1.5	-1.0	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.9	9.4	14.2	-3.8	1.2	-3.3	-2.9	-3.8	-3.4	-1.6	-3.3	-3.1	-3.3
Number of self-reported non-cancer illnesses	2.9	5.0	23.2	1.5	-4.8	0.8	2.2	0.9	2.4	0.7	1.9	1.3	2.5
Forced vital capacity (FVC), Best measure	2.8	10.2	16.9	-3.8	-0.5	-3.4	-3.1	-4.1	-3.2	-2.2	-3.4	-3.2	-3.4
Number of children fathered	2.8	3.2	9.9	-1.6	3.1	-1.3	-1.5	-1.2	-2.1	-0.7	-1.6	-1.6	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.8	3.3	6.4	-2.2	0.7	-0.5	-2.5	-2.3	-2.1	0.8	-2.2	-1.4	-2.1
Suffer from ‘nerves’	2.8	4.4	7.7	-2.3	0.3	-1.3	-2.7	-2.2	-2.7	-0.9	-2.8	-2.6	-1.3
Illnesses of father: High blood pressure	2.8	3.5	5.3	2.0	-2.2	2.3	1.5	1.9	2.0	0.1	1.7	1.6	2.2
Blood Platelet Count	2.7	31.6	59.6	6.3	-7.7	5.9	5.2	5.7	6.3	3.3	5.2	4.2	5.1
Hearing difficulty/problems: Yes	2.7	4.2	7.5	-2.3	0.7	-2.4	-2.2	-2.7	-2.3	-1.0	-2.2	-2.1	-1.5
Alcohol intake versus 10 years previously	2.7	4.0	19.5	-1.4	4.4	-2.1	-1.5	-1.0	-2.2	-0.2	-1.5	-1.3	-1.4
Diastolic blood pressure, automated reading	2.7	8.5	18.0	2.5	-4.2	2.3	3.1	2.8	3.2	1.8	2.7	2.4	3.3
Chronotype (morning person)	2.6	5.9	14.8	-2.9	3.8	-0.6	-2.5	-1.5	-3.1	-0.9	-2.7	-2.4	-2.0
Forced vital capacity (FVC)	2.6	10.0	15.6	-3.6	1.0	-3.4	-3.0	-4.0	-3.2	-2.5	-3.3	-3.3	-3.3
Pulse wave peak to peak time	2.6	3.1	5.1	-2.1	-1.1	-1.7	-1.9	-2.2	-1.6	-1.1	-1.9	-1.7	-1.9
Triglycerides	2.5	4.1	12.6	0.0	-3.5	2.9	0.0	2.5	3.0	0.0	0.0	0.0	2.0
Sitting height	2.4	16.8	26.2	-4.2	4.7	-3.4	-4.5	-4.4	-5.1	-2.4	-4.4	-4.1	-3.1
Mouth/teeth dental problems	2.2	3.4	17.2	-0.8	4.1	-2.0	-1.1	-1.3	-1.7	-1.4	-1.0	-0.8	-1.6
Pack years of smoking	2.2	3.3	5.2	-1.9	-0.3	-1.6	-2.2	-1.9	-2.2	0.1	-2.3	-2.3	-1.6
Systolic Blood Pressure	2.0	9.8	46.6	1.3	-6.8	1.9	2.7	1.6	3.4	2.9	2.3	2.2	2.4
Hair/balding pattern: Pattern 3	2.0	3.0	6.6	-2.2	-1.6	-2.2	-1.7	-2.6	-1.6	0.2	-1.8	-1.6	-0.8
Birth weight of first child	2.0	3.6	10.8	-1.0	3.3	-2.2	-1.5	-1.3	-1.7	-2.5	-1.3	-1.5	-1.4
Osteoarthritis (self-reported)	2.0	2.6	5.8	-2.4	1.6	-1.7	-1.3	-1.4	-2.0	0.8	-1.8	-1.5	-1.0
Verbal and Numeric Reasoning (VNR)	1.9	4.6	8.0	2.8	-1.6	1.0	2.5	1.2	2.8	0.9	2.8	2.7	1.7
Height	1.9	36.7	54.9	-6.7	4.5	-5.4	-7.2	-6.5	-7.4	-3.2	-6.9	-6.0	-5.4
Systolic blood pressure, automated reading	1.9	5.4	17.8	1.4	-4.2	1.3	2.3	1.9	2.6	2.3	2.0	2.1	1.9
Mouth/teeth dental problems: Dentures	1.9	3.3	26.0	0.5	-5.1	1.2	0.3	0.7	1.1	-0.2	0.1	-0.4	1.7
Pulse wave Arterial Stiffness index	1.9	2.3	4.1	1.8	1.5	1.4	1.5	2.0	1.2	0.8	1.6	1.3	1.6
Standing height	1.9	19.3	29.5	-4.6	3.8	-3.8	-5.1	-4.8	-5.4	-2.6	-5.0	-4.5	-3.6
Qualifications: College or University degree	1.9	5.9	11.2	3.3	-0.8	2.0	2.7	2.8	3.1	-0.7	2.9	2.4	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	6.2	-2.5	-1.5	-0.6	-1.1	-1.4	-1.1	2.4	-1.3	-0.5	-0.9
Relative age of first facial hair	1.8	3.6	6.1	1.9	-1.9	1.8	2.4	2.0	2.5	0.4	2.1	1.6	1.5
Relative age voice broke	1.8	2.7	5.6	1.2	-2.4	2.2	1.5	1.6	1.7	1.3	1.4	1.3	1.4
Medication: Levothyroxine sodium	1.8	3.0	10.3	1.8	-3.2	1.2	1.4	1.5	2.0	0.7	1.5	1.3	1.5
Medication for cholesterol	1.8	2.7	22.1	0.2	4.7	-0.1	0.2	0.5	-0.3	1.2	0.4	1.2	-1.1
Medication: Gliclazide	1.8	2.0	3.8	-1.9	0.8	-0.6	-1.9	-1.1	-1.9	1.0	-1.9	-1.2	-1.0
Ever taken oral contraceptive pill	1.8	2.0	2.8	1.5	1.6	1.1	1.7	1.4	1.3	0.7	1.7	1.5	1.3
Myopia	1.8	2.6	5.6	-2.1	1.1	-0.8	-1.7	-1.7	-2.4	0.4	-2.0	-1.7	-1.4
Lung FEV1/FVC ratio	1.7	8.5	35.9	-1.9	6.0	-3.2	-2.1	-1.8	-3.1	-1.7	-2.2	-2.2	-2.4
Handedness (chirality/laterality): Left-handed	1.7	2.0	3.8	-1.8	-0.0	-1.3	-1.9	-1.5	-1.7	-0.0	-1.8	-1.5	-0.7
Medication: Bendroflumethiazide	1.7	2.6	13.4	1.5	-3.7	0.6	1.5	1.2	1.8	-0.1	1.2	0.3	1.4
Irritability	1.7	2.9	5.4	-1.8	-0.6	-1.3	-2.3	-1.8	-1.9	-0.6	-2.2	-2.1	-1.1
Pack years adult smoking proportion	1.6	2.4	4.2	-1.7	-0.3	-1.4	-1.9	-1.7	-1.9	0.0	-2.0	-2.1	-1.2
Qualifications: None of the above	1.6	3.4	9.4	-3.1	0.7	-0.8	-1.7	-2.1	-2.1	1.1	-2.1	-1.7	-1.7
Exposure to tobacco smoke at home	1.6	1.8	3.5	-1.0	-1.9	-0.4	-1.5	-0.9	-1.1	-1.2	-1.4	-1.6	-1.7
Medication for cholesterol, blood pressure or diabetes	1.6	2.7	20.3	0.1	4.5	-0.7	-1.1	-0.1	-1.3	-1.4	-0.7	-0.5	-0.8
Medication: Omeprazole	1.6	1.9	4.2	-1.9	-2.0	0.5	-1.1	-1.0	-1.0	2.0	-1.2	-0.8	-1.1
Average weekly red wine intake	1.6	2.3	4.8	2.1	-0.7	0.9	1.6	1.0	1.9	-0.1	1.9	1.5	2.2
Reaction Time	1.5	2.9	5.9	-2.1	-0.9	0.4	-2.0	-1.6	-2.1	0.2	-2.3	-2.4	-0.9
Number of treatments/medications taken	1.5	2.8	17.5	-1.7	-4.2	-0.1	-0.7	-1.4	-0.6	0.9	-1.2	-1.3	-0.6
Supplements: Zinc	1.5	1.7	3.6	-1.9	0.4	-0.7	-1.6	-1.4	-1.3	-0.3	-1.6	-1.3	-1.4
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	3.2	1.8	-0.7	-0.1	1.7	1.6	1.6	-0.2	1.7	1.3	1.3
Worrier / anxious feelings	1.5	2.9	5.0	-2.0	-1.1	0.0	-2.2	-2.1	-2.1	0.0	-2.2	-1.8	-1.4
Tense / ‘highly strung’	1.5	2.4	4.7	-1.7	-1.3	-0.8	-2.2	-1.4	-1.7	-0.9	-2.0	-1.9	-0.7
Birth weight	1.5	3.3	19.7	-1.4	4.4	-1.4	-1.5	-0.8	-1.9	0.2	-1.3	-0.8	-1.0
Pain experienced in last month	1.5	2.6	4.1	1.8	-0.8	1.2	1.6	1.5	2.0	1.1	1.8	1.7	2.0
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	2.6	1.4	-1.5	1.3	1.3	1.5	1.6	0.7	1.3	1.0	1.3
Medication: Atenolol	1.4	1.7	2.5	1.1	-0.9	1.2	1.5	1.5	1.6	1.0	1.4	1.3	1.3
Arm fat-free mass (right)	1.4	7.3	13.3	-2.6	3.6	-3.3	-2.1	-2.7	-2.9	-2.6	-2.2	-2.3	-2.4
Mineral and other dietary supplements	1.4	1.9	3.8	1.6	1.0	1.5	1.4	1.7	1.3	0.1	1.4	1.2	2.0
Financial situation satisfaction	1.4	1.8	6.5	0.5	-1.3	2.2	0.3	1.1	0.5	2.5	0.6	1.2	0.9
Severe depression (siblings)	1.3	1.5	3.0	-1.4	-1.6	0.0	-1.7	-1.3	-1.1	-0.3	-1.5	-1.2	-0.7
Financial difficulties in last 2 years	1.3	1.8	3.7	1.9	-0.8	1.5	1.3	1.2	1.3	0.8	1.6	1.4	1.0
Neuroticism score	1.3	2.8	4.9	-1.9	-0.6	-0.2	-2.1	-1.7	-2.1	-0.4	-2.2	-2.2	-1.5
Medication: Lansoprazole	1.3	1.5	4.8	-1.9	1.4	-2.2	-0.7	-1.5	-0.9	0.7	-0.8	-0.4	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.1	-1.3	-0.2	-1.4	-1.6	-1.3	-1.6	-0.9	-1.8	-2.0	-1.2
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.6	-1.0	1.3	-1.5	-1.6	-0.7	-1.3	-1.1	-1.3	-1.1	-1.5
Irritable Bowel Disease (IBD)	1.2	2.8	8.8	1.8	-3.0	1.8	0.0	1.6	2.1	-0.2	1.6	1.3	1.2
Rheumatoid Arthritis	1.2	1.7	3.8	-0.9	0.1	-0.9	0.0	-1.5	-1.5	-1.9	-1.5	-1.7	-1.1
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.7	-1.6	0.7	-0.7	-0.9	-1.2	-1.3	0.4	-1.2	-1.3	-1.4
Hearing difficulty/problems with background noise	1.2	1.9	3.5	-1.7	-0.4	-0.8	-1.9	-1.5	-1.6	0.4	-1.8	-1.5	-1.4
Had menopause	1.2	1.5	3.8	-1.9	1.4	-1.1	-1.0	-1.1	-1.4	0.4	-1.3	-1.1	-0.9
Fluid intelligence score	1.2	2.6	5.1	1.7	-1.8	0.1	1.6	0.5	2.1	0.7	2.0	2.3	1.6
Pulse rate	1.2	2.1	7.3	1.3	-2.7	1.8	1.2	0.8	1.4	0.7	1.2	1.2	1.2
Blood clot in the leg (DVT)	1.2	1.5	4.3	0.5	-0.7	0.8	1.2	0.9	1.4	2.1	1.1	1.5	1.3
Glaucoma (self-reported)	1.2	1.5	2.5	1.2	-0.0	1.0	1.2	1.6	1.3	0.5	1.3	1.5	1.6
Age at first live birth	1.2	2.1	5.2	1.6	-2.3	1.6	1.2	0.9	1.8	-1.0	1.4	1.1	1.1
Arm predicted mass (right)	1.2	6.2	12.8	-2.5	3.6	-3.1	-1.8	-2.4	-2.6	-2.2	-2.0	-2.0	-2.1
Number of full sisters	1.2	1.5	4.2	1.0	0.1	2.0	1.3	0.6	0.9	1.7	1.2	1.4	0.5
Mood swings	1.2	2.2	5.3	-2.3	-0.3	-1.2	-1.6	-1.7	-1.7	1.1	-1.8	-1.4	-0.8
Medication: Atorvastatin	1.2	1.5	8.5	0.4	-2.9	0.6	1.1	0.8	1.4	-0.6	0.7	0.1	1.1
Ever depressed for a whole week	1.2	1.4	2.2	-1.2	-0.6	-1.2	-1.2	-1.5	-1.2	-0.6	-1.3	-1.5	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.3	-1.6	-1.5	0.1	-1.1	-1.0	-0.9	2.1	-1.1	-0.5	-0.8
Length of working week for main job	1.1	1.2	2.9	-1.7	1.3	-0.7	-0.9	-0.9	-1.2	1.2	-1.1	-0.8	-0.9
Neck or shoulder pain in last month	1.1	1.6	2.9	-1.7	-0.4	-0.8	-1.5	-1.2	-1.7	-0.3	-1.6	-1.3	-1.2
Chest pain or discomfort	1.1	1.6	11.4	-0.8	-3.4	0.6	-0.1	-0.9	0.2	1.3	-0.1	0.1	0.9
Average weekly champagne plus white wine intake	1.1	1.6	6.7	1.6	-1.5	0.7	0.6	0.9	1.2	-2.6	0.8	-0.0	0.3
Mother’s age at death	1.1	1.4	4.0	1.4	2.0	0.9	0.8	1.9	0.8	0.4	1.0	1.1	0.3
Medication: Blood pressure	1.1	2.1	11.4	-1.2	-3.4	-0.8	-0.7	-1.0	-0.4	-0.9	-1.2	-1.8	0.6
Medication: Lisinopril	1.1	1.4	3.8	0.8	-1.9	1.1	1.2	1.1	1.3	0.2	0.9	0.5	2.0
Breast Cancer	1.0	2.4	4.5	-1.8	2.1	-1.1	-2.0	-1.5	-1.9	-0.5	-1.7	-1.3	-0.2
Trunk predicted mass	1.0	5.4	12.0	-2.1	3.5	-3.2	-1.6	-1.9	-2.3	-2.3	-1.8	-2.0	-1.8
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.0	1.7	-0.3	0.8	1.2	1.4	1.6	-0.2	1.5	1.5	1.6
Age at last live birth	1.0	1.4	2.9	1.3	-1.7	0.5	1.1	0.6	1.6	-0.0	1.3	1.3	1.3
Knee pain experienced in last month	1.0	1.5	2.9	-1.4	0.4	-1.0	-1.4	-0.9	-1.5	-0.7	-1.6	-1.7	-1.1
Hypertension (Self-reported)	1.0	2.9	25.3	-0.3	-5.0	0.0	0.3	-0.4	0.7	-0.8	-0.2	-1.0	1.0
Ever had bowel cancer screening	1.0	1.2	2.5	-1.2	-1.6	-0.4	-1.1	-1.1	-0.9	-0.7	-1.2	-1.4	-0.7
Commuting to job workplace: Walk	1.0	1.0	3.5	-1.0	0.7	-0.7	-1.1	-1.0	-0.8	-0.8	-0.9	-0.7	-1.9
Intelligence (Savage-Jansen 2018)	0.9	2.8	6.2	2.5	-2.0	0.3	0.0	1.0	2.3	-0.0	2.2	2.1	1.3
Smoking Status	0.9	2.1	3.6	1.7	1.6	1.3	1.9	1.7	1.4	-0.5	1.8	1.4	0.5
Lung FVC	0.9	4.4	8.5	-2.9	-2.0	-2.4	-1.5	-2.8	-1.5	-0.0	-2.0	-2.1	-2.2
Neuroticism	0.9	2.1	3.8	-1.7	-1.1	-0.2	-1.8	-1.4	-1.7	-0.4	-1.9	-2.0	-0.8
Vitamin and mineral supplements	0.9	1.2	2.6	1.0	-0.4	1.6	0.7	1.4	1.1	1.4	0.9	1.3	0.8
Diabetes (father)	0.9	1.1	7.4	0.1	2.7	0.0	-0.4	0.1	-0.8	-1.2	-0.3	-0.5	-0.6
Diabetes (mother)	0.9	1.1	2.4	1.1	1.6	1.5	0.8	1.4	0.4	0.8	0.8	0.6	0.9
Average weekly fortified wine intake	0.9	1.0	6.4	-0.0	2.5	-1.1	-0.3	-0.3	-0.6	-1.2	-0.3	-0.7	-0.4
High blood pressure	0.9	2.4	19.0	-0.7	-4.4	-0.5	-0.1	-1.0	0.2	-0.8	-0.6	-1.3	0.5
Trunk fat-free mass	0.9	5.4	11.8	-2.1	3.4	-3.2	-1.6	-2.0	-2.3	-2.3	-1.8	-1.9	-1.8
Time employed in main current job	0.9	1.1	2.9	-0.6	0.8	-1.6	-0.7	-0.7	-0.5	-1.7	-0.6	-0.8	-1.5
Happiness	0.9	1.1	3.8	-1.2	-1.9	0.7	-0.9	-0.8	-1.0	1.0	-1.1	-0.9	-0.7
Illnesses of mother	0.9	1.1	7.2	-0.2	2.7	-0.7	-0.3	-0.4	-0.6	-0.7	-0.1	-0.0	-1.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	6.6	-1.3	0.3	0.8	-0.6	-0.7	-0.7	2.6	-0.6	0.3	-0.8
Headache pain in last month	0.9	1.5	2.9	-1.1	0.2	-0.7	-1.7	-1.3	-1.6	-0.9	-1.5	-1.3	-1.2
Chronic bronchitis/emphysema (mother)	0.9	1.0	1.6	0.9	-1.1	-0.3	1.2	1.2	1.3	1.0	1.1	1.0	0.5
Number of full brothers	0.9	1.1	2.6	0.8	0.0	1.2	1.3	1.1	0.9	1.6	1.1	1.0	0.2
Eye problems/disorders: None of the above	0.9	1.1	1.7	-0.4	0.4	-1.0	-1.1	-1.1	-1.1	-1.3	-1.0	-1.3	-1.3
Vascular/heart problems diagnosed by doctor	0.9	2.6	22.3	0.6	4.7	0.0	-0.2	0.7	-0.4	0.4	0.4	1.1	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	3.5	0.2	-0.9	0.8	0.8	0.5	1.1	1.9	0.9	1.4	1.1
Worry (Nagel 2018)	0.8	1.8	3.8	-1.9	-0.7	0.1	0.0	-1.7	-1.8	0.3	-1.9	-1.7	-0.8
High blood pressure (mother)	0.8	1.1	4.9	1.0	-2.2	0.6	0.7	0.7	0.9	-1.3	0.4	-0.3	0.9
Nervous feelings	0.8	1.5	2.5	-1.3	-1.4	0.2	-1.4	-1.1	-1.4	0.0	-1.6	-1.5	-1.5
Hair/balding pattern: Pattern 2	0.8	1.0	5.8	0.7	2.4	-0.7	0.1	0.8	-0.2	-1.3	0.1	-0.4	-0.9
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	2.3	-1.0	-1.5	-1.3	-0.2	-1.5	-0.5	0.0	-0.4	-0.6	-1.1
Arm fat percentage (right)	0.8	3.3	5.0	2.2	-0.5	1.9	2.0	2.1	1.7	0.8	2.0	1.8	2.2
Qualifications: A levels/AS levels or equivalent	0.8	1.7	5.1	2.3	-0.9	1.3	0.7	1.3	1.4	-0.9	1.2	1.0	1.6
Depression (self-reported)	0.8	0.9	2.8	1.0	-1.2	1.1	0.7	0.8	0.8	0.5	0.7	0.6	1.7
Hair/balding pattern: Pattern 4	0.8	1.9	6.8	-1.7	2.6	0.3	-1.1	-1.3	-1.6	0.4	-1.2	-0.7	-1.4
Ever highly irritable/argumentative for 2 days	0.8	0.9	1.7	-1.3	-0.2	-0.9	-1.1	-0.9	-1.2	0.2	-1.2	-1.3	-0.5
Medication: Amlodipine	0.8	1.1	5.1	-0.7	-2.3	-0.2	-0.5	-1.0	-0.5	-1.1	-0.8	-1.2	-0.3
High blood pressure (siblings)	0.8	1.1	2.0	-1.4	-1.1	-0.7	-1.1	-0.9	-0.9	-1.3	-1.2	-1.3	0.1
Medication: Blood pressure	0.8	1.3	10.2	-0.0	-3.2	0.4	0.9	-0.1	1.0	0.6	0.6	0.4	0.5
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.5	0.7	-0.6	0.9	1.6	1.0	1.6	0.6	1.4	1.2	1.2
Wears glasses or contact lenses	0.8	0.9	2.1	-1.5	1.0	-1.4	-0.8	-1.4	-0.9	0.2	-0.9	-0.5	0.2
Age at First Birth	0.7	1.1	3.5	-0.7	-0.8	-1.1	-0.8	-1.2	-0.4	-0.7	-0.9	-1.1	-1.9
Primary Biliary Cirrhosis	0.7	1.0	3.8	-0.7	-1.9	-0.4	0.0	-0.9	-0.9	-0.6	-1.3	-1.3	-0.4
Alcohol usually taken with meals	0.7	1.1	3.0	1.0	-1.7	0.3	1.0	0.6	1.3	-1.3	1.0	0.5	0.5
Pain all over the body in last month	0.7	0.7	3.4	-0.9	-0.6	-0.3	-0.3	-1.4	-0.4	-0.1	-0.4	-0.5	-1.8
Lung cancer (father)	0.7	0.8	2.2	-1.4	-0.2	-0.4	-0.8	-0.8	-0.9	0.7	-0.9	-0.7	-1.5
Medication: Ventolin 100micrograms inhaler	0.7	1.0	2.9	0.9	0.9	1.7	0.9	0.5	0.7	-0.2	1.2	1.4	-0.2
Exposure to tobacco smoke outside home	0.7	0.9	2.6	-1.6	-0.0	0.0	-0.9	-0.8	-1.0	0.1	-1.0	-0.7	-1.5
Mean time to correctly identify matches	0.7	1.3	3.2	-1.4	-0.6	0.9	-1.2	-0.8	-1.4	0.4	-1.6	-1.8	-0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.9	3.3	-1.2	0.7	-1.8	-0.1	-1.3	-0.4	0.8	-0.2	-0.0	-0.8
Medication: Aspirin	0.7	1.0	4.0	0.2	-1.5	1.0	0.7	0.3	0.7	0.8	0.5	0.3	2.0
Illnesses of siblings: Diabetes	0.7	0.9	4.4	0.1	-1.0	0.8	0.3	0.3	0.2	2.1	0.2	0.3	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.6	3.3	-1.8	-1.7	-0.0	-1.3	-1.4	-1.2	-0.6	-1.5	-1.3	-0.6
Whole body fat-free mass	0.7	4.1	9.7	-1.9	3.1	-2.7	-1.4	-1.9	-2.0	-2.0	-1.5	-1.6	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.9	-1.0	-0.2	-1.0	-0.7	-1.4	-0.5	-0.0	-0.7	-0.8	-1.2
Friendships satisfaction	0.7	0.9	2.4	0.6	-1.5	1.2	0.7	1.0	1.2	-0.0	0.8	0.8	0.7
Back pain experienced in last month	0.7	1.0	4.6	-0.1	2.1	-1.1	-0.3	0.3	-0.8	-1.6	-0.4	-0.9	-0.1
Medication: Aspirin	0.7	0.9	3.7	0.1	-1.9	0.9	0.7	0.0	0.7	0.7	0.4	0.2	1.8
Whole body water mass	0.7	3.8	8.8	-1.8	3.0	-2.6	-1.3	-1.8	-2.0	-2.0	-1.4	-1.5	-1.5
Guilty feelings	0.7	1.1	5.1	-1.0	-2.3	0.8	-1.0	-0.8	-0.8	0.6	-1.0	-0.9	0.2
Arm fat-free mass (left)	0.7	3.4	10.2	-1.6	3.2	-2.4	-1.1	-1.5	-1.9	-1.8	-1.3	-1.4	-1.3
Arm predicted mass (left)	0.7	3.3	10.0	-1.7	3.2	-2.3	-1.2	-1.5	-1.9	-1.6	-1.4	-1.4	-1.2
Neuroticism (Nagel 2018)	0.6	1.3	2.6	-1.4	-1.4	0.1	0.0	-1.3	-1.4	0.0	-1.6	-1.6	-0.3
Mean Putamen Volume	0.6	0.7	4.4	-1.0	0.2	-0.2	-0.5	-0.7	-0.4	2.1	-0.3	0.2	-0.6
Fasting Glucose	0.6	0.7	1.7	0.2	-1.0	0.5	0.7	0.4	0.9	1.3	0.9	1.2	0.6
Ever had hysterectomy (womb removed)	0.6	0.7	2.1	-1.5	0.2	-0.8	-0.7	-0.7	-0.9	-0.6	-1.0	-1.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.6	0.7	0.5	1.2	0.5	1.0	0.2	1.3	0.5	0.7	1.0
Angina	0.6	0.8	3.9	0.4	-0.2	1.1	1.1	0.4	0.6	0.3	0.8	0.5	2.0
Multivitamins +/- minerals	0.6	0.8	1.9	-0.5	0.4	-1.3	-0.6	-0.8	-0.8	-1.4	-0.8	-1.2	-0.3
Hip circumference	0.6	2.5	10.4	-1.1	3.2	-1.3	-1.2	-1.1	-2.0	-1.3	-1.2	-1.2	-0.7
Noisy workplace	0.6	0.8	2.4	-1.3	0.3	-0.0	-0.8	-0.2	-0.7	1.6	-0.8	-0.3	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.0	-1.0	0.4	-0.1	-0.8	-0.6	-0.9	1.4	-0.9	-0.8	-0.9
Breastfed as a baby	0.6	0.7	4.5	-0.6	-2.1	-0.1	-0.5	-0.5	-0.3	0.8	-0.7	-0.6	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.8	4.8	0.4	-2.2	0.3	-0.2	0.3	0.5	1.4	0.1	0.4	0.2
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.2	-0.6	-0.9	0.5	-1.1	-0.5	-0.8	0.5	-1.0	-0.9	-1.0
Medication for pain relief, constipation, heartburn	0.6	1.0	4.3	1.1	1.9	0.1	0.3	0.5	0.4	-2.1	0.6	0.4	-0.6
Pulse rate, automated reading	0.6	1.8	8.2	1.4	-2.9	1.7	0.9	0.8	1.2	-0.3	0.8	0.2	1.2
Smoking status: Previous	0.6	0.9	2.0	0.8	0.8	0.9	1.4	1.1	0.9	0.2	1.3	1.2	0.4
Loneliness, isolation	0.6	0.9	1.4	-1.1	-0.3	-1.1	-1.0	-0.8	-1.1	0.8	-1.2	-1.0	-0.7
Qualifications: nursing, teaching	0.6	1.0	5.1	0.1	2.2	-0.8	-0.9	0.4	-0.9	-1.2	-0.7	-0.7	-0.3
Eye problems/disorders: Cataract	0.6	0.7	1.7	0.7	0.8	0.5	1.3	1.1	0.8	-0.4	0.9	0.5	1.0
Breast cancer (self-reported)	0.6	0.7	1.7	-1.3	0.2	-1.2	-0.7	-1.1	-0.6	-0.8	-0.7	-0.7	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.7	-1.6	-0.7	-1.4	-0.8	-1.6	-1.0	0.6	-1.1	-0.8	-1.2
Commuting to job workplace: Public transport	0.6	0.7	3.8	1.1	0.5	0.2	-0.5	0.9	-0.1	-1.9	-0.2	-0.6	0.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.9	-1.2	-1.2	-0.7	-0.6	-1.1	-0.5	0.5	-0.6	-0.1	-1.4
Ever smoked	0.6	1.0	8.8	-0.6	3.0	0.2	0.1	-0.1	-0.6	-0.0	-0.0	-0.0	-0.8
Basal metabolic rate	0.6	3.2	8.1	-1.6	2.8	-2.3	-1.2	-1.7	-1.9	-1.7	-1.3	-1.4	-1.3
Alzheimer’s Disease (in father)	0.5	0.6	1.3	0.5	0.3	0.3	0.8	0.7	0.7	1.1	0.7	0.6	1.1
Medication for hormone replacement therapy	0.5	0.6	3.5	-0.7	-1.9	-0.5	-0.0	-0.9	0.0	0.2	-0.2	-0.2	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.2	-0.9	-0.7	0.0	-1.1	-0.5	-0.9	0.6	-1.0	-0.8	-0.7
Qualifications: CSEs or equivalent	0.5	0.7	1.7	-0.8	-0.3	-0.4	-0.9	-0.7	-0.9	0.2	-1.0	-0.9	-1.3
Waist circumference	0.5	1.7	3.3	1.5	0.4	1.0	1.4	1.5	1.1	0.8	1.5	1.3	1.8
Medication: Ramipril	0.5	0.7	2.2	-1.1	-1.5	-0.6	-0.6	-0.7	-0.4	-0.1	-0.9	-1.0	0.1
Health satisfaction	0.5	0.7	2.6	-1.6	0.2	0.1	-0.4	-0.5	-0.9	1.2	-0.9	-0.8	-0.4
Angina (self-reported)	0.5	0.6	3.7	0.2	-0.1	0.9	0.9	0.1	0.4	0.2	0.6	0.3	1.9
Medication: Ibuprofen	0.5	0.6	2.5	-0.8	-0.2	0.2	-0.5	-0.4	-0.6	1.6	-0.7	-0.8	-0.9
Heart disease (mother)	0.5	0.6	1.7	-1.3	-0.4	-0.1	-0.8	-0.8	-0.8	0.3	-1.0	-1.0	-0.4
Supplements: Vitamin C	0.5	0.6	4.4	-0.6	2.1	-0.9	-0.0	-0.6	-0.4	0.2	-0.1	-0.1	-0.5
Number of operations (self-reported)	0.5	0.8	3.3	-0.4	0.7	-1.2	-0.5	-0.5	-0.5	-1.8	-0.5	-1.0	-0.4
Supplements: Calcium	0.5	0.6	2.1	-0.7	-0.9	-1.5	0.2	-1.4	-0.1	-0.4	-0.1	-0.3	-0.4
Basal cell carcinoma (self-reported)	0.5	0.6	3.7	-0.7	-0.0	-1.9	-0.1	-0.4	-0.2	-0.5	-0.3	-0.6	-0.8
Ovarian Cancer	0.4	0.5	2.0	-0.5	1.4	-0.9	-0.3	0.1	-0.5	-1.0	-0.3	-0.5	-0.4
Neuroticism (2016)	0.4	0.6	4.3	-0.3	-2.1	1.0	-0.6	-0.5	-0.1	0.4	-0.3	-0.1	-0.4
Blood Eosinophil Count	0.4	2.8	9.3	-0.5	-2.7	1.9	1.4	-0.2	1.4	3.0	1.1	1.7	0.3
BMI	0.4	2.4	3.8	1.2	0.7	1.4	1.9	1.7	1.4	1.5	1.8	1.9	1.7
Leg fat-free mass (left)	0.4	1.9	5.4	-1.2	2.3	-1.6	-0.9	-1.2	-1.5	-1.5	-1.0	-1.0	-1.0
Hand grip strength (right)	0.4	1.0	2.5	1.4	-0.9	-0.7	0.7	0.8	1.2	-1.6	1.0	0.8	0.6
Fed-up feelings	0.4	0.8	1.7	-1.1	0.3	0.2	-1.0	-0.9	-1.3	0.9	-1.1	-0.9	-0.2
Serious illness, injury or assault to yourself	0.4	0.4	1.7	-0.8	-1.3	0.0	0.8	-0.9	0.4	0.5	0.3	0.1	0.5
Body mass index (BMI)	0.4	1.6	3.4	1.4	0.7	0.7	1.8	1.5	1.2	0.2	1.7	1.4	1.1
Impedance of leg (left)	0.4	2.0	5.1	-1.3	-1.0	0.2	-2.2	-1.4	-1.7	0.9	-2.0	-1.4	-0.8
Leg predicted mass (left)	0.4	2.0	5.6	-1.2	2.4	-1.6	-1.0	-1.3	-1.5	-1.5	-1.0	-1.0	-1.0
Past tobacco smoking	0.4	0.7	2.5	-0.6	-1.6	-0.8	-1.0	-1.0	-0.6	0.3	-0.9	-0.9	0.0
Heart attack	0.4	0.5	1.9	-0.5	-1.4	-0.5	-0.1	-0.2	0.1	1.0	-0.1	-0.1	1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	0.7	-0.0	1.2	0.1	0.8	0.3	1.1	0.4	0.9	0.0
Impedance of arm (right)	0.4	1.8	7.3	0.4	-2.7	2.1	-0.9	0.4	0.0	1.7	-0.5	-0.0	1.3
Father’s age at death	0.4	0.5	1.2	0.7	1.1	0.4	-0.7	-0.0	-0.6	-1.1	-0.5	-0.8	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.7	-1.0	-0.6	0.3	-0.6	-0.9	-1.0	-0.3	-1.0	-1.3	-0.8
Medication: Paracetamol	0.4	0.7	1.3	-1.0	-0.2	-1.1	-0.7	-0.9	-1.0	0.2	-0.9	-0.8	-0.7
Leg fat percentage (right)	0.4	1.4	2.3	1.5	0.5	0.9	1.4	1.5	1.0	0.7	1.4	1.3	1.4
Wheeze or whistling in the chest in last year	0.4	0.7	4.1	-0.6	-1.2	0.5	-0.3	-0.6	-0.3	2.0	-0.1	0.5	0.2
Medication: Seretide 50 evohaler	0.4	0.4	1.7	0.9	-0.8	0.0	0.5	0.0	0.5	-1.3	0.7	0.5	-0.3
Overall health rating	0.4	0.8	3.2	-0.1	-1.8	1.4	0.1	0.1	-0.0	1.1	-0.2	-0.5	0.9
Leg fat-free mass (right)	0.4	2.4	6.5	-1.5	2.6	-1.7	-1.1	-1.5	-1.7	-1.4	-1.1	-1.1	-1.3
Arm fat percentage (left)	0.4	1.6	2.8	1.7	-0.0	1.4	1.4	1.4	1.1	0.6	1.4	1.3	1.5
Osteoporosis (self-reported)	0.4	0.5	1.7	-0.3	-1.3	-0.6	-0.3	-0.5	-0.1	-0.7	-0.4	-0.5	-1.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.5	0.9	1.2	0.3	0.0	0.9	0.2	0.8	0.5	0.7	-0.5
Leg predicted mass (right)	0.4	2.3	6.2	-1.5	2.5	-1.7	-1.0	-1.4	-1.6	-1.4	-1.1	-1.0	-1.2
Miserableness	0.4	0.6	1.0	-1.0	-0.8	0.1	-0.8	-0.6	-0.8	1.0	-0.9	-0.5	-1.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.1	-0.7	0.8	-0.3	-0.6	-0.6	-1.1	-0.4	-0.9	-1.0	-0.5
Unable to work because of sickness or disability	0.4	0.5	1.1	1.0	1.0	0.5	0.4	0.9	0.2	0.1	0.5	0.2	1.0
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	-0.7	-1.3	-0.6	-0.2	-0.3	-0.0	1.0	-0.3	-0.2	1.1
Depressed Affect (Nagel 2018)	0.3	0.7	1.7	-1.3	-0.5	-0.4	0.0	-0.9	-1.2	0.9	-1.2	-0.8	-0.0
Alzheimer’s Disease (including proxy)	0.3	0.5	1.4	-0.2	-1.2	0.4	-0.2	0.7	0.2	1.2	-0.1	0.3	1.1
Body Mass Index (BMI) (2010)	0.3	0.4	3.5	0.0	1.9	-0.3	0.0	-0.3	-0.8	0.0	0.0	0.0	-0.4
HbA1C	0.3	0.4	1.9	-0.1	1.4	-0.0	0.2	0.3	0.1	0.7	0.3	0.7	0.7
Blood Red Count	0.3	2.4	4.1	-1.0	1.9	-1.2	-1.9	-1.1	-2.0	-1.8	-1.8	-1.9	-0.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.2	-0.1	0.6	1.1	-0.5	0.5	-0.4	0.9	-0.4	-0.2	0.5
Current tobacco smoking	0.3	0.5	2.2	0.7	1.5	0.5	0.5	0.6	0.1	-0.1	0.5	0.3	0.9
Stomach or abdominal pain in last month	0.3	0.4	1.8	-0.4	-0.4	0.3	-0.8	-0.2	-0.6	1.4	-0.7	-0.5	-0.1
Chronic bronchitis/emphysema (father)	0.3	0.3	1.5	-0.8	-1.2	0.6	0.2	-0.2	-0.2	0.7	-0.3	-0.2	-0.3
Illnesses of siblings	0.3	0.5	1.9	0.9	1.4	-0.3	0.2	0.4	0.2	0.0	0.5	0.6	-1.1
Weight	0.3	1.2	5.8	-0.8	2.4	-1.1	-0.6	-0.8	-1.3	-0.9	-0.7	-0.7	-0.6
Number of live births	0.3	0.4	2.0	0.1	1.4	-1.0	0.4	0.0	0.3	-0.1	0.4	0.5	-0.3
Asthma	0.3	0.5	1.5	-0.6	0.9	-0.5	-0.3	-1.2	-0.7	0.3	-0.2	0.2	-1.2
Impedance of arm (left)	0.3	1.5	3.9	-0.7	-1.7	1.3	-2.0	-0.8	-1.2	0.9	-1.5	-1.0	0.1
Shortness of breath walking on level ground	0.3	0.3	1.1	0.3	-0.3	0.5	0.5	0.7	0.3	1.0	0.3	0.1	1.1
Family relationship satisfaction	0.3	0.4	1.6	-0.2	-1.3	0.5	-0.1	0.1	-0.0	-1.2	-0.2	-0.7	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-0.8	0.2	0.1	-0.3	-1.2	-0.7	1.0	-0.5	-0.2	0.2
Diabetes diagnosed by doctor	0.3	0.4	2.4	-0.5	-0.3	-0.0	-0.5	0.1	-0.5	1.6	-0.5	-0.3	0.8
Eye problems/disorders: Glaucoma	0.3	0.4	0.9	0.5	0.5	-0.0	0.5	0.6	0.6	0.7	0.6	0.9	0.8
Alcohol drinker status: Never	0.3	0.4	1.7	0.1	0.9	-0.1	-0.6	-0.1	-0.4	-1.3	-0.4	-0.6	-0.1
Average weekly beer plus cider intake	0.3	0.4	2.3	-0.8	-1.5	0.1	-0.3	-0.3	-0.1	0.3	-0.3	-0.1	-0.9
Commuting to job workplace: Cycle	0.3	0.4	1.0	-0.1	-1.0	0.8	-0.7	-0.4	-0.4	-0.5	-0.6	-0.6	-0.2
Impedance of whole body	0.3	1.6	4.2	-0.8	-1.4	1.1	-2.1	-1.1	-1.4	1.0	-1.6	-1.1	-0.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.7	-0.5	-0.9	0.1	-0.4	0.4	-0.2	0.2	-0.4	0.0	0.7
Ulcerative Colitis (UC)	0.2	0.5	1.1	1.0	0.0	0.3	0.0	1.1	0.8	-1.0	0.7	0.4	0.4
Prostate Cancer	0.2	0.3	1.9	0.5	-1.4	-0.1	0.0	0.5	0.7	-0.0	0.4	0.0	0.5
Heel T-Score	0.2	1.3	4.1	1.3	2.0	0.3	1.3	1.1	0.9	0.1	1.1	0.8	1.3
Respiratory disease	0.2	0.5	1.5	-0.6	1.2	-0.7	-0.7	-1.0	-0.9	-0.1	-0.5	-0.1	-0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.6	0.3	0.5	-0.2	0.2	0.8	0.1	1.2	0.2	0.2	1.3
Sensitivity / hurt feelings	0.2	0.4	1.3	-0.2	-1.1	0.3	-0.2	-0.4	-0.4	-0.8	-0.6	-1.0	-0.6
Medication: Co-codamol	0.2	0.2	1.0	0.2	1.0	-0.7	0.2	0.3	-0.0	-0.4	0.1	-0.2	-0.1
Impedance of leg (right)	0.2	1.1	2.9	-0.7	-1.3	0.4	-1.7	-0.9	-1.2	0.8	-1.5	-1.1	-0.2
Townsend deprivation index at recruitment	0.2	0.3	0.5	-0.4	-0.6	0.7	-0.4	-0.2	-0.5	-0.2	-0.5	-0.5	-0.7
Maternal smoking around birth	0.2	0.3	0.9	-0.5	-0.3	-0.7	0.8	-0.3	0.5	-1.0	0.4	-0.0	-0.6
Taking other prescription medications	0.2	0.3	0.6	-0.7	-0.8	-0.6	-0.3	-0.5	-0.4	0.4	-0.5	-0.6	-0.3
Hayfever, allergic rhinitis or eczema	0.2	0.3	0.8	-0.0	0.8	0.7	0.4	0.1	0.1	0.8	0.5	0.9	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.9	-0.4	-0.1	-0.6	-0.6	-0.8	-0.6	1.0	-0.5	-0.3	-0.2
Had other major operations	0.2	0.2	1.8	-0.1	0.3	0.1	-0.3	0.0	-0.2	-1.3	-0.3	-0.5	-0.1
Allergy	0.2	0.5	1.7	-0.1	-0.7	-0.5	-0.7	-0.2	-0.3	-1.3	-0.7	-1.1	-0.5
Diabetes (self-reported)	0.2	0.4	2.0	-0.5	0.0	-0.6	-0.4	-0.1	-0.5	1.4	-0.4	-0.4	0.4
Arm fat mass (right)	0.2	0.7	1.4	1.0	0.7	0.7	0.8	1.0	0.4	0.2	0.8	0.8	1.2
Pulse wave reflection index	0.2	0.3	0.8	-0.3	0.9	0.5	-0.4	0.2	-0.5	0.8	-0.3	-0.0	0.4
Loud music exposure frequency	0.2	0.2	0.6	0.2	0.6	0.6	0.6	0.4	0.1	0.4	0.4	0.5	-0.8
Gout (self-reported)	0.2	0.3	1.6	0.1	-0.4	-0.5	-0.6	0.6	-0.1	1.3	-0.3	-0.2	-0.0
Worry too long after embarrassment	0.2	0.4	1.1	-0.4	-0.7	0.3	-0.5	-0.7	-0.5	-1.1	-0.5	-0.6	-0.8
Emphysema/chronic bronchitis	0.2	0.2	0.6	0.6	-0.5	-0.2	0.4	0.5	0.6	-0.2	0.4	-0.3	0.8
Leg pain on walking	0.2	0.3	1.8	-0.2	0.4	-1.4	-0.2	-0.4	-0.2	-0.4	-0.2	-0.4	-0.1
Illnesses of father: Heart disease	0.2	0.3	1.0	-0.3	-0.4	-0.3	0.0	-0.7	0.0	-1.0	-0.0	-0.2	1.0
Long-standing illness, disability or infirmity	0.2	0.4	2.9	-0.3	-1.7	0.1	0.2	-0.2	0.0	0.8	0.0	-0.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.0	-0.2	-1.0	0.2	-0.0	0.1	-0.1	-0.6	-0.3	-0.7	0.0
Asthma (self-reported)	0.2	0.3	1.1	-0.3	1.1	-0.2	-0.0	-0.8	-0.4	0.4	0.1	0.6	-0.7
Smoking status: Current	0.2	0.3	1.8	0.4	1.3	0.3	0.1	0.4	-0.1	0.0	0.2	0.2	0.5
Hearing aid user	0.2	0.3	1.4	-0.4	-0.5	-1.2	-0.4	-0.3	-0.3	0.0	-0.4	-0.3	0.2
Leg fat percentage (left)	0.2	0.6	0.9	1.0	0.7	0.5	0.8	0.9	0.4	0.5	0.9	0.8	0.8
Heart disease (siblings)	0.2	0.3	0.8	-0.9	0.0	0.3	-0.2	-0.6	-0.6	0.7	-0.5	-0.5	0.3
Depression (Nagel 2018)	0.1	0.2	0.4	-0.6	-0.4	0.5	0.0	-0.4	-0.4	0.5	-0.5	-0.2	0.6
HDL Cholesterol	0.1	0.2	1.5	0.0	0.9	-1.2	0.0	-0.1	-0.4	0.0	0.0	0.0	-0.2
Allergy or Eczema	0.1	0.2	1.6	-0.3	0.3	0.1	-0.1	-0.4	-0.2	1.3	0.0	0.5	-0.1
Hair Pigment	0.1	1.7	4.8	-1.1	2.2	-2.0	-0.8	-1.4	-1.2	-0.3	-0.8	-0.5	-1.3
Tanning	0.1	1.7	3.0	-1.6	-0.8	-1.2	-1.4	-1.7	-1.2	-1.1	-1.4	-1.2	-0.7
Hand grip strength (left)	0.1	0.2	1.3	0.1	0.1	-0.9	-0.1	-0.1	0.0	-1.1	-0.1	-0.2	-0.1
Medication: Metformin	0.1	0.2	0.6	0.3	0.8	0.3	0.4	0.5	0.1	0.2	0.3	-0.0	0.7
Trunk fat percentage	0.1	0.2	0.7	0.1	0.1	0.9	-0.3	-0.1	-0.5	0.6	-0.1	0.2	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.2	-0.1	0.1	0.3	0.3	0.6	-0.0	0.5	-0.0	-0.2	1.1
Supplements: Glucosamine	0.1	0.1	0.5	-0.2	0.2	-0.2	-0.2	-0.2	-0.4	-0.7	-0.2	-0.2	-0.5
Trunk fat mass	0.1	0.4	1.3	-0.5	1.2	-0.1	-0.8	-0.7	-1.1	0.0	-0.6	-0.4	-0.0
Number of incorrect matches in round	0.1	0.2	0.5	0.1	0.0	0.6	-0.6	0.3	-0.6	0.4	-0.4	0.0	0.7
Falls in the last year	0.1	0.2	0.6	-0.5	0.7	0.1	0.1	-0.6	-0.3	0.8	-0.1	-0.2	-0.4
Body fat percentage	0.1	0.4	1.1	0.7	0.1	1.0	0.4	0.5	0.1	0.7	0.5	0.7	1.0
Migraine (self-reported)	0.1	0.1	0.4	-0.2	0.6	0.6	-0.2	-0.2	-0.4	-0.6	-0.1	0.0	-0.2
Medication: Allopurinol	0.1	0.1	0.3	0.1	-0.0	-0.5	-0.1	0.6	0.2	0.3	0.1	0.1	-0.4
Whole body fat mass	0.1	0.3	1.6	-0.3	1.3	0.1	-0.4	-0.3	-0.9	0.1	-0.4	-0.2	0.2
Leg fat mass (right)	0.1	0.4	1.3	0.7	1.1	0.5	0.7	0.7	0.1	0.2	0.6	0.6	0.7
Had major operations	0.1	0.1	0.3	0.2	-0.2	-0.3	-0.1	0.4	-0.2	-0.2	-0.2	-0.5	0.2
Arm fat mass (left)	0.1	0.4	0.7	0.7	0.8	0.6	0.6	0.6	0.1	0.1	0.6	0.6	0.7
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.9	-0.2	-0.1	-0.1	-0.4	0.1	-0.4	-0.1	-0.6	-0.9	0.3
Medication: Paracetamol	0.1	0.1	0.3	-0.0	-0.5	-0.2	0.5	0.1	0.2	0.5	0.2	0.1	0.2
Risk taking	0.1	0.2	0.9	-0.3	0.1	-0.6	0.1	0.0	0.1	-1.0	-0.1	-0.4	-0.7
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.7	-0.1	0.8	-0.0	-0.1	-0.0	-0.3	0.4	-0.2	-0.6	0.2
Age started oral contraceptive pill	0.1	0.2	0.6	-0.2	0.7	-0.7	-0.2	-0.1	-0.3	-0.6	-0.2	-0.3	0.3
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.4	-0.1	0.3	0.4	0.1	0.4	-0.1	0.1	-0.1	-0.2	0.6
Leg fat mass (left)	0.0	0.2	1.3	0.3	1.1	0.3	0.2	0.3	-0.3	0.2	0.2	0.3	0.3

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