Best TWAS P=1.71e-08 · Best GWAS P=1.51e-06 conditioned to 0.969
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | CDK2AP1 | 0.17 | 0.10 | enet | 18 | 0.11 | 4.6e-07 | 4.4 | -5.2 | 2.0e-07 | -0.78 | 0.03 | 0.94 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | RILPL2 | 0.09 | 0.09 | blup | 43 | 0.08 | 3.1e-05 | 4.5 | 5.6 | 1.7e-08 | 0.85 | 0.01 | 0.97 | TRUE |