Best TWAS P=1.38e-08 · Best GWAS P=9.81e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | DPP3 | 0.04 | 0.05 | lasso | 2 | 0.05 | 1.9e-05 | -5.7 | -5.7 | 1.4e-08 | 1.00 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | B3GNT1 | 0.02 | 0.02 | blup | 30 | 0.02 | 7.5e-04 | -5.0 | 5.2 | 2.0e-07 | -0.51 | 0.01 | 0.94 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CNIH2 | 0.03 | 0.00 | enet | 4 | 0.02 | 6.4e-03 | 4.9 | -5.2 | 2.1e-07 | 0.36 | 0.02 | 0.65 | TRUE |