[Hub]/) : Traits : Alcohol intake versus 10 years previously :

chr1:752,566-1,907,912

Best TWAS P=1.54e-08 · Best GWAS P=4.21e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-54O7.17 0.28 0.28 lasso 3 0.30 3.8e-17 -4.3 5.2 2.6e-07 -0.83 0.11 0.88 FALSE
2 GTEx Breast Mammary Tissue (Female) UBE2J2 0.14 0.00 lasso 4 0.00 4.6e-01 -5.5 -5.5 5.1e-08 0.95 0.01 0.64 FALSE
3 GTEx Esophagus Gastroesophageal Junction RP11-54O7.17 0.24 0.07 enet 10 0.06 4.0e-03 -5.5 5.5 4.7e-08 -0.93 0.00 0.97 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic RP11-54O7.17 0.23 0.10 enet 16 0.14 3.1e-08 -5.5 5.3 9.8e-08 -0.88 0.00 1.00 FALSE
5 GTEx Skin Sun Exposed Lower leg RP11-54O7.17 0.19 0.07 lasso 6 0.12 9.4e-10 -4.3 5.3 1.5e-07 -0.82 0.01 0.98 FALSE
6 GTEx Spleen RP11-54O7.17 0.31 0.22 enet 6 0.20 6.8e-06 -5.5 5.6 2.2e-08 -0.94 0.00 0.98 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma C1orf170 0.20 0.21 lasso 5 0.21 8.2e-24 -5.5 5.6 2.1e-08 -0.99 0.00 1.00 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C1orf170 0.14 0.16 enet 5 0.14 3.9e-06 -5.5 5.7 1.5e-08 -0.98 0.00 1.00 TRUE
9 The Cancer Genome Atlas Prostate Adenocarcinoma C1orf170 0.22 0.24 lasso 4 0.24 1.9e-25 -5.5 5.6 1.9e-08 -0.99 0.00 1.00 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma PLEKHN1 0.04 0.01 lasso 5 0.02 4.7e-03 -4.3 5.2 2.5e-07 -0.79 0.00 0.76 FALSE