TWAS hub - C1orf170

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.204	0.0526	0.0e+00	0.206	0.180	0.204	NA	0.213	6.8e-23	5.1e-20	1.1e-22	NA	8.2e-24
2	TCGA	Pheochromocytoma and Paraganglioma	0.144	0.0550	6.1e-05	0.163	0.093	0.138	NA	0.057	5.2e-07	1.5e-04	3.8e-06	NA	2.6e-03
3	TCGA	Prostate Adenocarcinoma	0.223	0.0574	0.0e+00	0.239	0.232	0.245	NA	0.245	1.0e-24	6.3e-24	2.1e-25	NA	1.9e-25
4	TCGA	Testicular Germ Cell Tumors	0.156	0.0770	6.0e-03	0.047	0.001	0.016	NA	0.025	9.3e-03	2.9e-01	9.0e-02	NA	4.5e-02
5	TCGA	Thyroid Carcinoma	0.070	0.0270	5.1e-06	0.062	0.070	0.066	NA	0.073	1.2e-06	2.4e-07	5.4e-07	NA	1.3e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Alcohol intake versus 10 years previously	13.3	19.9	32.0	5.6	5.7	5.6	1.0	1.8
High blood pressure (mother)	6.6	9.3	16.1	3.8	4.0	3.9	0.0	0.3
Alcohol intake frequency.	6.3	14.7	25.0	4.8	5.0	4.8	0.8	1.4
Medication: Bendroflumethiazide	6.2	9.3	13.2	3.6	3.6	3.6	1.8	2.1
Number of operations (self-reported)	5.8	8.7	14.1	-3.7	-3.8	-3.7	-0.9	-1.1
Illnesses of father: High blood pressure	5.6	6.9	9.7	3.1	3.1	3.0	2.0	1.6
Financial situation satisfaction	5.3	6.6	9.6	-2.9	-3.1	-2.9	-1.6	-2.1
Falls in the last year	4.9	6.7	8.9	-3.0	-2.8	-2.8	-2.4	-1.7
Mother’s age at death	4.1	5.2	7.9	2.8	2.7	2.7	1.3	1.1
Other serious medical condition/disability diagnosed by doctor	4.0	5.2	5.7	-2.3	-2.2	-2.3	2.2	2.4
Hair/balding pattern: Pattern 3	3.9	5.8	9.7	3.1	3.1	3.1	-0.2	-0.3
Medication: Blood pressure	3.9	7.4	8.8	2.9	3.0	2.8	2.2	2.6
Medication: Ramipril	3.8	4.9	8.9	2.8	3.0	2.8	-0.3	0.4
Heel bone mineral density (BMD) T-score, automated (right)	3.7	8.5	23.7	1.0	0.5	0.9	-4.1	-4.9
Lupus	3.6	5.5	9.5	-2.9	-3.1	-3.0	-0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	3.5	7.9	22.4	1.0	0.6	0.9	-3.9	-4.7
Hypertension (Self-reported)	3.3	9.0	13.0	3.4	3.6	3.5	1.7	2.3
Medication for hormone replacement therapy	3.2	3.5	4.5	-1.9	-2.1	-2.1	1.8	1.4
Illnesses of mother	3.2	4.0	6.4	-2.4	-2.5	-2.5	0.9	0.9
Medication for cholesterol	2.8	4.3	7.8	-1.6	-1.4	-1.3	-2.8	-2.7
Basal cell carcinoma (self-reported)	2.8	3.3	5.7	-1.6	-1.4	-1.5	2.4	2.1
Hypothyroidism (self reported)	2.6	6.0	10.1	-3.2	-3.1	-3.2	0.5	0.2
High blood pressure	2.6	7.3	10.1	3.0	3.2	3.1	1.7	2.2
Number of full sisters	2.6	3.1	5.2	-2.2	-2.3	-2.2	0.9	-0.0
Vascular/heart problems diagnosed by doctor	2.6	7.1	9.1	-2.8	-3.0	-2.9	-2.1	-2.3
Waist Hip Ratio (WHR)	2.4	10.9	18.7	4.0	4.3	4.2	0.4	1.3
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	4.1	1.8	1.9	2.0	-1.4	-1.0
Lung FEV1/FVC ratio	2.2	11.2	14.5	3.4	3.8	3.5	2.6	3.2
Relative age of first facial hair	2.2	4.5	7.3	-2.7	-2.7	-2.6	-0.6	-0.8
Medication: Levothyroxine sodium	2.2	3.8	6.6	-2.4	-2.5	-2.6	0.1	-0.5
Diabetes (self-reported)	2.2	3.4	5.3	-1.8	-1.7	-1.7	-1.6	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.5	8.0	-2.8	-2.6	-2.7	0.2	0.4
Ever had prostate specific antigen (PSA) test	2.2	2.5	3.6	1.6	1.7	1.7	-1.9	-0.7
Cardiovascular Disease	2.1	6.8	8.3	2.5	2.9	2.7	2.0	2.9
Worry too long after embarrassment	2.1	3.6	6.1	2.5	2.4	2.4	-0.4	0.4
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	3.1	-1.7	-1.8	-1.8	0.8	0.6
Prospective memory result	1.9	2.4	5.1	0.9	0.9	0.8	2.3	2.1
Comparative body size at age 10	1.9	5.2	8.9	2.9	3.0	2.9	0.2	0.8
Had major operations	1.9	2.3	3.5	-1.9	-1.7	-1.7	-1.2	-0.8
Supplements: Fish oil (including cod liver oil)	1.9	2.5	5.3	1.0	0.7	0.8	-2.3	-2.3
Risk taking	1.9	2.8	4.8	1.8	2.2	2.1	0.5	0.9
Heel T-Score	1.8	14.7	48.9	-0.6	-1.6	-1.0	-4.6	-7.0
Townsend deprivation index at recruitment	1.8	2.5	4.0	-2.0	-1.9	-1.9	-0.7	-0.9
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	3.1	-1.2	-1.3	-1.3	1.8	1.7
Osteoporosis (self-reported)	1.8	2.2	8.0	-0.0	0.4	0.2	1.7	2.8
Eye problems/disorders: Glaucoma	1.8	2.1	4.9	0.7	0.7	0.8	-2.2	-2.0
Unable to work because of sickness or disability	1.8	2.3	3.0	-1.7	-1.7	-1.7	1.1	1.2
Chronic bronchitis/emphysema (father)	1.7	1.9	3.3	-1.8	-1.8	-1.8	-0.2	-0.0
Neuroticism	1.6	3.9	5.3	2.2	2.3	2.3	1.2	1.6
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	3.3	-1.1	-1.1	-1.0	-1.8	-1.5
Exposure to tobacco smoke at home	1.6	1.8	3.3	-1.8	-1.6	-1.8	0.3	0.0
Qualifications: College or University degree	1.6	5.0	8.1	1.8	1.7	1.6	2.9	2.8
Breast cancer (self-reported)	1.6	1.9	4.6	-1.0	-0.9	-0.9	1.4	2.1
Age started oral contraceptive pill	1.6	2.0	3.3	1.8	1.7	1.8	0.8	0.3
Commuting to job workplace: Cycle	1.6	2.0	3.2	-1.7	-1.8	-1.8	-0.2	-0.8
Average weekly fortified wine intake	1.5	1.7	3.6	0.9	0.7	0.8	-1.9	-1.8
Heart disease (mother)	1.5	1.8	3.1	1.6	1.8	1.7	0.1	0.2
Suffer from ‘nerves’	1.5	2.3	2.7	1.5	1.5	1.6	-1.6	-1.3
Illnesses of father: Heart disease	1.5	2.1	2.6	1.6	1.5	1.5	-1.1	-1.4
Breast Cancer	1.4	3.3	8.1	0.4	0.7	0.5	2.7	2.9
Tense / ‘highly strung’	1.4	2.3	3.3	1.8	1.8	1.8	0.9	1.1
Birth weight of first child	1.4	2.6	4.1	2.0	2.0	2.0	0.8	0.5
Hypothyroidism/myxoedema (self-reported)	1.4	2.6	4.4	-2.0	-2.0	-2.1	0.1	-0.8
High blood pressure (siblings)	1.4	2.0	3.6	1.8	1.9	1.8	0.4	0.5
Medication: Blood pressure	1.4	2.4	3.0	1.4	1.6	1.4	1.6	1.7
Frequency of depressed mood in last 2 weeks	1.3	1.9	3.1	-1.8	-1.6	-1.7	0.4	0.8
Medication: Metformin	1.3	1.8	3.0	-1.7	-1.7	-1.7	-0.0	-0.5
Number of incorrect matches in round	1.3	2.2	3.0	1.5	1.7	1.7	1.1	1.3
Mouth/teeth dental problems: Dentures	1.3	2.2	3.7	1.9	1.9	1.9	0.7	0.1
Long-standing illness, disability or infirmity	1.3	2.0	6.4	-0.5	-0.3	-0.4	1.8	2.5
Qualifications: nursing, teaching	1.3	2.0	3.5	1.9	1.7	1.8	-0.2	0.1
Irritability	1.3	2.2	6.5	-0.6	-0.5	-0.6	1.8	2.6
Pack years of smoking	1.3	1.9	3.0	1.6	1.7	1.7	0.7	0.6
Neuroticism (Nagel 2018)	1.2	2.8	4.2	1.9	2.0	1.9	0.9	1.3
Sitting height	1.2	8.7	15.6	-3.7	-4.0	-3.8	-0.4	-0.2
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	2.7	1.3	1.5	1.4	0.8	1.6
Number of full brothers	1.2	1.5	2.1	-1.1	-1.3	-1.4	-0.7	-1.5
Diabetes diagnosed by doctor	1.2	2.0	2.6	-1.6	-1.4	-1.5	-1.1	-1.4
Illnesses of father: None of the above (group 1)	1.2	1.4	2.5	-1.6	-1.5	-1.5	0.2	0.6
Ever taken oral contraceptive pill	1.2	1.4	2.1	-1.5	-1.2	-1.3	0.9	0.8
Pack years adult smoking proportion	1.1	1.6	2.6	1.5	1.6	1.6	0.7	0.6
Illnesses of siblings	1.1	1.6	2.5	-1.6	-1.6	-1.6	0.6	0.2
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.3	-1.4	-1.5	-1.5	0.3	0.2
Loneliness, isolation	1.1	1.5	4.4	-0.8	-0.4	-0.6	1.4	2.1
Wears glasses or contact lenses	1.1	1.3	3.3	0.3	0.2	0.3	-1.8	-1.7
Commuting to job workplace: Public transport	1.1	1.4	2.4	-1.5	-1.5	-1.5	0.1	-0.1
Medication: Lisinopril	1.1	1.5	2.5	1.6	1.4	1.4	0.4	0.9
Diastolic blood pressure, automated reading	1.1	3.5	8.1	0.7	0.7	0.6	2.8	2.8
Smoking Status	1.0	2.3	3.3	-1.6	-1.8	-1.7	-1.2	-1.2
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.6	0.3	0.1	0.2	1.9	1.7
Current tobacco smoking	1.0	1.7	2.4	-1.6	-1.6	-1.5	-0.9	-0.7
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	5.0	-0.1	0.2	0.1	1.3	2.2
Time employed in main current job	1.0	1.1	1.8	1.2	1.3	1.3	-0.7	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.6	-1.5	-1.6	-1.6	-0.3	-0.1
Pulse wave reflection index	1.0	1.2	2.8	-0.6	-0.7	-0.6	-1.7	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.1	-1.4	-1.4	-1.4	0.0	-0.0
Medication: Aspirin	1.0	1.3	1.8	1.1	1.0	1.0	1.4	1.2
Medication: Atorvastatin	1.0	1.2	2.1	-1.5	-1.3	-1.4	0.6	0.4
Worry (Nagel 2018)	0.9	2.0	2.9	1.6	1.7	1.6	0.7	1.1
Average weekly spirits intake	0.9	1.2	1.7	-1.3	-1.1	-1.1	-0.5	-1.2
Medication: Co-codamol	0.9	1.0	3.1	0.1	0.3	0.2	1.3	1.8
Qualifications: CSEs or equivalent	0.9	1.2	1.6	-1.2	-1.2	-1.1	-1.0	-0.9
Nervous feelings	0.9	1.6	2.3	1.3	1.5	1.4	0.8	1.1
Neuroticism score	0.9	1.8	2.5	1.3	1.4	1.4	1.1	1.6
Glaucoma (self-reported)	0.9	1.1	2.8	0.2	0.1	0.3	-1.7	-1.6
Forced vital capacity (FVC), Best measure	0.9	3.3	4.7	-2.1	-2.2	-2.1	-1.5	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	1.8	1.3	1.4	1.3	0.2	0.3
Number of self-reported non-cancer illnesses	0.9	1.5	2.2	1.1	1.3	1.3	0.9	1.5
Ever depressed for a whole week	0.9	1.1	1.4	-1.0	-1.1	-1.2	0.8	1.1
Alzheimer’s Disease (in father)	0.8	0.9	1.0	1.0	1.0	0.9	0.7	1.0
Blood Red Count	0.8	7.9	13.8	3.5	3.6	3.7	-0.7	-0.3
Systolic Blood Pressure	0.8	4.2	10.9	-0.1	0.1	-0.1	3.1	3.3
Systolic blood pressure, automated reading	0.8	2.2	5.7	-0.1	-0.2	-0.3	2.4	2.3
Severe depression (siblings)	0.8	0.9	3.0	-0.1	-0.2	0.0	-1.2	-1.7
Multivitamins +/- minerals	0.8	1.0	3.0	0.3	0.4	0.3	1.3	1.7
Hearing difficulty/problems with background noise	0.8	1.3	1.6	1.2	1.3	1.2	0.9	1.0
Forced vital capacity (FVC)	0.8	3.0	4.2	-1.6	-1.8	-1.6	-2.0	-1.6
Length of working week for main job	0.8	0.9	1.6	-1.2	-1.2	-1.3	-0.2	-0.2
Exposure to tobacco smoke outside home	0.8	1.1	3.2	-0.0	0.2	0.2	-1.8	-1.5
Medication for pain relief, constipation, heartburn	0.8	1.3	2.9	-0.7	-0.8	-0.8	-1.4	-1.7
Mean time to correctly identify matches	0.8	1.6	2.6	1.6	1.6	1.6	0.2	0.2
Medication: Paracetamol	0.8	1.3	3.6	0.3	0.3	0.3	1.6	1.9
Height	0.7	13.3	21.9	-4.3	-4.7	-4.4	-2.0	-1.8
Type 2 Diabetes (T2D) (2018)	0.7	1.4	1.7	-1.2	-1.1	-1.1	-1.2	-1.3
Hand grip strength (right)	0.7	2.0	5.1	-0.6	-0.3	-0.4	2.1	2.3
Worrier / anxious feelings	0.7	1.3	1.8	1.3	1.3	1.2	0.6	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.6	0.3	0.5	0.4	1.3	1.9
Smoking status: Previous	0.7	1.1	1.3	-1.0	-1.1	-1.1	-1.0	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.1	-0.6	-0.5	-0.6	0.8	1.4
Eye problems/disorders: Cataract	0.7	0.8	1.1	-1.1	-0.7	-0.9	0.5	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.5	0.2	0.3	0.2	1.2	1.6
Mineral and other dietary supplements	0.7	0.9	1.3	-1.1	-0.9	-1.0	0.8	0.9
Medication: Aspirin	0.7	0.9	1.9	0.5	0.5	0.5	1.3	1.4
Cholesterol lowering medication	0.7	1.0	2.1	0.6	0.7	0.6	1.4	1.4
Alzheimer’s Disease (including proxy)	0.6	0.8	1.5	1.2	1.1	1.1	-0.4	-0.0
BMI	0.6	3.6	5.1	1.8	1.7	1.6	2.3	2.0
Waist circumference	0.6	2.0	2.9	1.7	1.7	1.7	0.9	0.9
Financial difficulties in last 2 years	0.6	0.8	1.1	-1.0	-1.0	-0.9	-1.1	-0.1
Mouth/teeth dental problems	0.6	0.9	1.9	-0.8	-0.7	-0.7	-1.4	-0.9
Noisy workplace	0.6	0.8	2.1	-0.1	-0.3	-0.2	-1.3	-1.5
Standing height	0.6	6.3	10.7	-3.2	-3.3	-3.2	0.3	0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.1	-0.3	-0.1	-0.1	1.2	1.5
Blood clot in the leg (DVT)	0.6	0.8	1.2	-1.1	-1.1	-1.0	0.7	0.6
Medication: Paracetamol	0.6	0.9	2.9	-0.2	-0.1	-0.1	1.3	1.7
Commuting to job workplace: Car/motor vehicle	0.6	0.6	1.0	0.9	0.8	0.8	-1.0	-0.4
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	-0.1	-0.3	-0.2	-1.0	-1.6
Average weekly beer plus cider intake	0.6	0.8	1.3	-1.0	-1.1	-1.1	-0.4	-0.5
Supplements: Calcium	0.6	0.7	1.4	0.6	0.7	0.6	0.8	1.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	0.9	-1.0	-1.0	-0.9	0.8	0.7
Depressed Affect (Nagel 2018)	0.5	1.1	1.4	1.0	1.2	1.1	0.8	0.9
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	0.7	0.6	0.7	-1.1	-0.8
Ulcerative Colitis (UC)	0.5	0.9	2.8	0.0	-0.4	-0.4	1.7	1.1
Hearing difficulty/problems: Yes	0.5	0.8	2.1	0.3	0.3	0.2	1.5	1.2
Maternal smoking around birth	0.5	0.7	1.2	-1.0	-1.0	-1.1	0.2	0.3
Serious illness, injury or assault to yourself	0.5	0.6	1.0	-1.0	-0.9	-0.9	-0.4	0.0
Stomach or abdominal pain in last month	0.5	0.6	1.8	0.2	0.2	0.1	1.0	1.4
Past tobacco smoking	0.5	0.9	1.1	0.9	1.0	1.0	0.8	1.0
Qualifications: None of the above	0.5	1.1	3.0	-0.5	-0.5	-0.4	-1.4	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.0	-0.8	-1.0	-0.9	-0.4	-0.5
Peak expiratory flow (PEF)	0.5	1.1	1.4	1.1	1.1	1.2	-1.2	-0.7
Pulse wave peak to peak time	0.5	0.6	1.7	0.2	0.4	0.3	1.1	1.3
Emphysema/chronic bronchitis	0.5	0.5	1.0	0.5	0.5	0.5	0.9	1.0
Medication: Ibuprofen	0.5	0.6	1.2	-0.4	-0.4	-0.4	-1.0	-1.1
Overall health rating	0.5	1.1	3.4	-0.5	-0.4	-0.5	1.2	1.8
Knee pain experienced in last month	0.5	0.7	1.7	-0.6	-0.6	-0.6	-1.3	-0.9
Illnesses of siblings: Diabetes	0.5	0.6	2.0	-0.1	-0.1	0.0	-1.0	-1.4
Friendships satisfaction	0.5	0.6	0.9	-0.9	-0.8	-0.9	0.3	0.7
Smoking status: Current	0.5	0.8	0.9	-1.0	-1.0	-0.9	-0.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.4	1.2	1.1	1.2	-0.9	-0.4
Average weekly champagne plus white wine intake	0.5	0.7	2.1	0.1	-0.0	-0.1	1.4	1.2
Ever smoked	0.5	0.9	1.8	-0.5	-0.6	-0.5	-1.3	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.5	0.6	0.8	0.8	0.8	0.7	0.7
Irritable Bowel Disease (IBD)	0.4	1.0	2.8	0.0	-0.8	-0.8	1.7	1.1
Blood Eosinophil Count	0.4	2.7	4.5	-2.1	-2.0	-2.1	0.7	0.6
Blood Platelet Count	0.4	4.5	8.0	-2.6	-2.8	-2.7	0.3	-0.1
Lung FVC	0.4	1.9	5.2	0.2	0.1	0.2	-2.3	-2.1
Leg fat-free mass (left)	0.4	2.0	2.4	-1.4	-1.4	-1.4	1.3	1.5
Relative age voice broke	0.4	0.5	0.8	-0.8	-0.9	-0.8	-0.3	-0.7
Age when periods started (menarche)	0.4	1.0	2.2	0.5	0.7	0.8	-1.5	-1.2
Medication: Atenolol	0.4	0.5	0.9	0.5	0.6	0.5	0.6	1.0
Leg predicted mass (left)	0.4	2.2	2.4	-1.5	-1.5	-1.5	1.3	1.6
Had other major operations	0.4	0.5	0.6	-0.7	-0.7	-0.8	0.7	0.5
Trunk fat-free mass	0.4	2.3	2.8	-1.6	-1.7	-1.7	1.1	1.4
Pulse rate	0.4	0.7	1.0	-0.8	-0.8	-0.8	-0.6	-1.0
Asthma	0.4	0.8	1.5	-1.2	-1.1	-1.0	-0.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.4	0.8	-0.5	-0.5	-0.4	-0.9	-0.9
Depression (self-reported)	0.4	0.5	1.4	0.1	0.1	0.1	1.2	1.0
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	-0.5	-0.7	-0.5	-0.8	-0.9
Trunk predicted mass	0.4	2.4	2.9	-1.7	-1.7	-1.7	1.1	1.5
Hair/balding pattern: Pattern 4	0.4	1.0	1.8	1.3	1.2	1.3	0.3	-0.3
Birth weight	0.4	0.9	2.1	0.5	0.3	0.3	-1.4	-1.4
Comparative height size at age 10	0.4	2.3	4.0	-1.9	-2.0	-1.9	-0.4	0.1
Age at last live birth	0.4	0.6	1.7	-0.2	-0.3	-0.2	-1.3	-1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	-0.2	-0.1	-0.2	1.3	0.9
Whole body fat-free mass	0.4	2.0	2.4	-1.4	-1.5	-1.5	1.2	1.5
Whole body water mass	0.4	2.2	2.5	-1.5	-1.5	-1.5	1.2	1.6
Arm fat mass (left)	0.4	1.4	2.6	1.0	0.9	0.8	1.6	1.5
Guilty feelings	0.4	0.6	2.0	-0.2	-0.0	-0.1	1.0	1.4
Depression (Nagel 2018)	0.3	0.5	0.8	-0.9	-0.8	-0.9	-0.1	0.4
Ovarian Cancer	0.3	0.3	0.6	-0.8	-0.7	-0.7	-0.1	-0.5
Hand grip strength (left)	0.3	0.8	1.9	0.2	0.5	0.4	1.2	1.4
Number of treatments/medications taken	0.3	0.5	1.8	0.2	0.3	0.2	0.7	1.3
Ever had hysterectomy (womb removed)	0.3	0.3	0.7	-0.6	-0.8	-0.7	-0.0	-0.3
Vitamin and mineral supplements	0.3	0.4	1.3	-0.0	-0.1	0.0	-0.9	-1.1
Diabetes (father)	0.3	0.3	0.4	0.6	0.6	0.7	0.5	0.5
Diabetes (mother)	0.3	0.4	0.6	0.7	0.8	0.8	0.4	0.5
Trunk fat percentage	0.3	1.1	1.6	1.3	1.1	1.1	1.0	0.6
Fed-up feelings	0.3	0.5	1.1	-0.5	-0.3	-0.4	1.1	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.3	-0.4	-0.3	-0.3	0.7	1.2
Body mass index (BMI)	0.3	1.3	1.6	1.3	1.1	1.1	1.3	0.9
Hair/balding pattern: Pattern 2	0.3	0.4	0.6	-0.6	-0.6	-0.7	0.6	0.8
Pain all over the body in last month	0.3	0.3	0.5	-0.3	-0.5	-0.4	-0.7	-0.7
Fluid intelligence score	0.3	0.7	1.8	-0.5	-0.6	-0.6	1.3	0.9
Impedance of arm (right)	0.3	1.2	2.0	-1.4	-1.4	-1.4	-0.3	-0.3
Arm fat percentage (right)	0.3	1.2	2.7	0.8	0.6	0.6	1.6	1.3
Father’s age at death	0.3	0.4	1.0	0.6	0.3	0.5	-0.4	-1.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.2	-0.2	-0.2	-0.1	-1.8	-1.1
Gout (self-reported)	0.3	0.4	0.8	-0.4	-0.5	-0.4	-0.9	-0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.6	-0.7	-0.4	-0.5	0.4	0.8
Body fat percentage	0.3	1.2	1.7	1.3	1.2	1.2	1.1	0.6
Age at first live birth	0.3	0.6	1.0	1.0	1.0	0.9	-0.4	0.2
Eye problems/disorders: None of the above	0.3	0.4	0.5	0.7	0.7	0.6	0.5	0.5
Medication: Omeprazole	0.3	0.4	0.5	0.7	0.7	0.7	0.2	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	-0.3	-0.2	-0.2	-1.1	-0.5
Whole body fat mass	0.3	1.1	2.2	0.9	0.7	0.7	1.5	1.2
Leg pain on walking	0.3	0.4	1.0	-0.1	-0.1	-0.0	-0.9	-1.0
Leg fat-free mass (right)	0.3	1.7	2.0	-1.2	-1.3	-1.3	1.2	1.4
Arm fat percentage (left)	0.3	1.4	2.4	1.1	1.0	0.9	1.6	1.2
Asthma (self-reported)	0.3	0.5	1.0	-1.0	-0.9	-0.8	-0.3	-0.2
Leg predicted mass (right)	0.3	1.7	1.9	-1.2	-1.4	-1.3	1.2	1.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.6	-0.8	-0.8	-0.7	0.1	0.1
Basal metabolic rate	0.3	1.8	2.4	-1.2	-1.3	-1.3	1.3	1.6
Leg fat percentage (left)	0.3	1.0	1.7	1.3	1.2	1.2	0.7	0.1
Reaction Time	0.2	0.3	0.5	0.7	0.7	0.7	-0.2	-0.4
Neuroticism (2016)	0.2	0.2	0.6	0.0	-0.6	-0.5	-0.8	-0.1
Chronotype (morning person)	0.2	0.4	0.6	0.8	0.7	0.6	0.8	0.2
Supplements: Glucosamine	0.2	0.3	0.5	-0.5	-0.6	-0.6	0.1	-0.7
Trunk fat mass	0.2	0.8	1.4	0.9	0.7	0.7	1.2	0.9
Had menopause	0.2	0.3	0.5	0.7	0.4	0.5	-0.4	-0.7
Allergy	0.2	0.6	1.2	1.1	0.9	0.9	-0.2	-0.4
Medication: Simvastatin	0.2	0.2	0.4	0.6	0.6	0.6	-0.1	-0.2
Weight	0.2	0.8	2.0	-0.1	-0.3	-0.3	1.4	1.4
Number of live births	0.2	0.3	0.4	-0.7	-0.5	-0.6	-0.2	0.5
Happiness	0.2	0.3	0.5	-0.7	-0.7	-0.7	0.2	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	0.4	0.3	0.3	1.2	0.8
Medication: Lansoprazole	0.2	0.3	0.5	0.4	0.3	0.2	-0.7	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.2	-0.1	-0.0	0.0	-1.5	-0.8
Impedance of arm (left)	0.2	0.8	1.3	-1.1	-1.1	-1.1	-0.4	-0.5
Arm fat mass (right)	0.2	1.0	2.3	0.6	0.4	0.4	1.5	1.3
Breastfed as a baby	0.2	0.3	0.9	0.0	0.0	-0.0	0.9	0.8
Loud music exposure frequency	0.2	0.2	0.2	0.3	0.4	0.4	-0.4	-0.5
Headache pain in last month	0.2	0.4	0.9	-0.7	-0.5	-0.6	0.4	0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.7	-0.2	-0.5	-0.4	-0.8	-0.8
Leg fat percentage (right)	0.2	0.7	0.9	0.9	0.9	0.9	0.9	0.4
Shortness of breath walking on level ground	0.2	0.3	1.0	0.2	0.4	0.3	-1.0	-0.1
Neck or shoulder pain in last month	0.2	0.3	0.8	-0.6	-0.2	-0.3	-0.9	-0.5
Medication: Seretide 50 evohaler	0.2	0.3	0.4	-0.7	-0.5	-0.5	0.3	0.5
Leg fat mass (right)	0.2	0.7	1.8	0.5	0.4	0.4	1.4	1.1
Family relationship satisfaction	0.2	0.2	0.3	0.5	0.5	0.5	0.1	0.3
Supplements: Vitamin C	0.2	0.2	0.3	0.6	0.4	0.4	0.4	0.4
Average weekly red wine intake	0.2	0.3	0.6	-0.7	-0.6	-0.7	-0.3	-0.1
Mood swings	0.2	0.3	0.5	0.5	0.7	0.7	-0.2	0.6
Ever had bowel cancer screening	0.2	0.2	0.4	-0.1	-0.6	-0.5	-0.6	0.0
Osteoarthritis (self-reported)	0.2	0.2	0.9	-0.1	-0.2	-0.1	-0.4	-0.9
Hearing aid user	0.2	0.3	0.4	0.5	0.5	0.4	-0.6	-0.7
High cholesterol (Self-reported)	0.2	0.4	0.6	0.7	0.8	0.7	-0.6	-0.2
Alcohol drinker status: Never	0.2	0.2	0.3	0.5	0.5	0.4	0.4	0.6
Arm fat-free mass (left)	0.2	1.2	2.7	-0.7	-0.8	-0.8	1.3	1.6
Leg fat mass (left)	0.2	0.7	1.5	0.8	0.6	0.7	1.2	0.9
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.8	-0.3	-0.4	-0.4	0.9	0.6
Blood White Count	0.1	0.7	2.5	0.0	0.1	0.0	1.0	1.6
Respiratory disease	0.1	0.3	0.4	-0.7	-0.5	-0.5	0.4	0.6
Tanning	0.1	0.9	1.6	-1.3	-1.2	-1.2	0.1	0.2
Sensitivity / hurt feelings	0.1	0.2	0.6	0.3	0.3	0.4	0.5	0.8
Angina	0.1	0.1	0.1	0.2	0.4	0.3	-0.1	0.2
Supplements: Zinc	0.1	0.1	0.3	-0.3	-0.2	-0.3	0.4	0.5
Taking other prescription medications	0.1	0.2	0.4	-0.5	-0.4	-0.4	0.1	0.7
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	0.2	0.1	0.2	-0.6	-0.3
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.3	0.3	0.5	0.5	0.2	0.4
Impedance of leg (left)	0.1	0.5	1.4	0.2	0.2	0.2	-1.1	-1.2
Alcohol usually taken with meals	0.1	0.2	0.3	0.5	0.6	0.6	-0.4	0.2
Heart attack	0.1	0.1	0.2	0.3	0.3	0.3	0.3	0.5
Hip circumference	0.1	0.6	1.0	-0.8	-1.0	-1.0	0.5	0.4
Medication: Cholesterol lowering	0.1	0.2	0.8	-0.3	-0.2	-0.1	-0.3	-0.9
Lung cancer (father)	0.1	0.1	0.2	0.1	0.2	0.2	0.4	0.4
Medication: Amlodipine	0.1	0.1	0.1	-0.4	-0.3	-0.3	-0.3	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.4	-0.1	-0.0	-0.0	0.0	-0.6
Arm fat-free mass (right)	0.1	0.4	0.8	-0.4	-0.5	-0.4	0.8	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.1	0.0	0.2	-0.6	-0.3
Wheeze or whistling in the chest in last year	0.1	0.2	0.7	0.1	0.4	0.4	0.4	0.9
Number of children fathered	0.1	0.2	0.5	0.2	0.1	0.2	0.7	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.4	-0.5	-0.4	-0.1	0.0
Health satisfaction	0.1	0.1	0.3	0.2	0.3	0.3	-0.1	0.6
Medication: Allopurinol	0.1	0.1	0.2	0.5	0.4	0.5	0.0	-0.2
Arm predicted mass (right)	0.1	0.3	0.6	-0.4	-0.5	-0.5	0.7	0.8
Pulse rate, automated reading	0.1	0.2	0.4	-0.7	-0.4	-0.5	0.1	0.3
Chest pain or discomfort	0.1	0.2	0.5	-0.1	0.1	0.1	0.7	0.7
Medication: Gliclazide	0.1	0.1	0.3	0.3	0.3	0.3	0.6	0.3
Miserableness	0.1	0.2	0.3	-0.5	-0.5	-0.5	0.5	0.3
Fractured/broken bones in last 5 years	0.1	0.2	0.6	0.0	0.2	0.0	0.4	0.7
Myopia	0.1	0.2	0.6	0.2	0.0	0.1	0.3	0.8
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.3	0.4	0.4	0.4	0.5	0.5
Heart disease (siblings)	0.1	0.1	0.3	-0.3	-0.4	-0.3	-0.3	-0.5
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.1	0.2	0.1	0.4	0.3
Impedance of whole body	0.1	0.5	1.2	-0.2	-0.2	-0.2	-1.0	-1.1
Arm predicted mass (left)	0.1	0.7	1.2	-0.7	-0.8	-0.7	0.9	1.1
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.2	0.0	-0.1	-0.0	0.1	0.4
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2017)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.1	0.1	0.1	0.0	-0.3	-0.3
Age at First Birth	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Allergy or Eczema	0.0	0.1	0.3	-0.1	0.0	-0.0	-0.6	-0.0
Hair Pigment	0.0	0.9	1.8	-0.7	-1.0	-1.0	-0.5	-1.3
Impedance of leg (right)	0.0	0.2	0.5	-0.3	-0.2	-0.2	-0.7	-0.7
Ever highly irritable/argumentative for 2 days	0.0	0.1	0.1	0.2	0.3	0.2	0.3	0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	0.0	-0.0	-0.1	-0.3	0.2
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.2	0.1	0.1	0.2	0.4	0.1
Angina (self-reported)	0.0	0.0	0.1	-0.0	0.2	0.1	0.0	0.3
Migraine (self-reported)	0.0	0.0	0.1	-0.2	-0.2	-0.3	-0.0	-0.0
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.0	-0.0	-0.1	0.1	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.1	0.2	0.3	0.1	-0.0	0.2
Back pain experienced in last month	0.0	0.0	0.2	-0.3	0.0	-0.0	-0.4	-0.0
Pain experienced in last month	0.0	0.0	0.1	0.1	-0.1	-0.1	0.3	-0.2

Hub : Genes

C1orf170

Models

Trait associations