Best TWAS P=2.26e-08 · Best GWAS P=9.98e-09 conditioned to 0.00226
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | POC5 | 0.17 | 0.16 | lasso | 5 | 0.15 | 5.2e-18 | -5.2 | 5.4 | 6.1e-08 | -0.90 | 0.02 | 0.98 | FALSE |
| 2 | METSIM | Adipose | POLK | 0.05 | 0.01 | enet | 16 | 0.03 | 4.3e-05 | -4.7 | -5.6 | 2.3e-08 | 0.58 | 0.35 | 0.63 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | POLK | 0.03 | 0.01 | lasso | 7 | 0.02 | 3.9e-03 | -4.4 | -5.2 | 1.8e-07 | 0.81 | 0.22 | 0.69 | FALSE |